Bioactive Peptides as Therapeutic Adjuvants for Cancer

References

• Holohan C, Van Schaeybroeck S, Longley DB, Johnston PG. Cancer drug resistance: an evolving paradigm. Nat Rev Cancer. 2013; 13(10):714–26. doi:10.1038/nrc3599
   PubMed Web of Science ®Google Scholar
• Witt CM, Balneaves LG, Cardoso MJ, Cohen L, Greenlee H, Johnstone P, Kücük O, Mailman J, Mao JJ. A comprehensive definition for integrative oncology. JNCI Monogr. 2017; 2017(52). doi:10.1093/jncimonographs/lgx012
   Google Scholar
• Singh BP, Vij S, Hati S. Functional significance of bioactive peptides derived from soybean. Peptides. 2014; 54:171–9. doi:10.1016/j.peptides.2014.01.022
   PubMed Web of Science ®Google Scholar
• Fields F, Falla TJ, Rodan K, Bush L. Bioactive peptides: signaling the future. J Cosmet Dermatol. 2009;8(1):8–13. doi:10.1111/j.1473-2165.2009.00416.x
   PubMed Web of Science ®Google Scholar
• Blackadar CB. Historical review of the causes of cancer. World J Clin Oncol. 2016; 7(1):54. v7.i1.54 doi:10.5306/wjco
   PubMed Web of Science ®Google Scholar
• Tanaka T, Shimizu M, Kochi T, Moriwaki H. Chemical-induced carcinogenesis. J Exp Clin Med. 2013; 5(6):203–9. doi:10.1016/j.jecm.2013.10.009
   Google Scholar
• Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 68(6):394–424. 2018; doi:10.3322/caac.21492
   PubMed Web of Science ®Google Scholar
• Qureshi M, Zelinski E, Carlson LE. Cancer and complementary therapies: current trends in survivors' interest and use. Integr Cancer Ther. 2018; 17(3):844–53. doi:10.1177/1534735418762496
   PubMed Web of Science ®Google Scholar
• National Center for Complementary and Integrative Health. 2018. Complementary, Alternative or Integrative, What’s in a name? Retrieved from https://nccih.nih.gov/health/integrative-health.
   Google Scholar
• Viscardo-Gutierrez DL, Zavala-Gonzales JC. Bioactive peptides: little giants in health. Rev. Soc. Peruana Med. Int. 2016; 29 (4)
   Google Scholar
• Cicero AFG, Fogacci F, Colletti A. Potential role of bioactive peptides in prevention and treatment of chronic diseases: a narrative review. Br J Pharmacol. 2017; 174(11):1378–94. doi:10.1111/bph.13608
   PubMed Web of Science ®Google Scholar
• Chalamaiah M, Yu W, Wu J. Immunomodulatory and anticancer protein hydrolysates (peptides) from food proteins: A review. Food Chem. 2018; 245:205–22. doi:10.1016/j.foodchem.2017.10.087
   PubMed Web of Science ®Google Scholar
• Blanco-Míguez A, Gutiérrez-Jácome A, Pérez-Pérez M, Pérez-Rodríguez G, Catalán-García S, Fdez-Riverola F, Lourenço A, Sánchez B. From amino acid sequence to bioactivity: The biomedical potential of antitumor peptides. Protein Sci. 2016; 25(6):1084–95. doi:10.1002/pro.2927
   PubMed Web of Science ®Google Scholar
• Luna Vital DA, González de Mejía E, Dia VP, Loarca-Piña G. Peptides in common bean fractions inhibit human colorectal cancer cells. Food Chem. 2014; 157:347–55. doi:10.1016/j.foodchem.2014.02.050
   PubMed Web of Science ®Google Scholar
• Song R, Wei R, Luo H, Yang Z. Isolation and identification of an antiproliferative peptide derived from heated products of peptic hydrolysates of half-fin anchovy (Setipinna taty). J Funct Foods. 2014; 10:104–11. doi:10.1016/j.jff.2014.06.010
   Web of Science ®Google Scholar
• Umayaparvathi S, Meenakshi S, Vimalraj V, Arumugam M, Sivagami G, Balasubramanian T. Antioxidant activity and anticancer effect of bioactive peptide from enzymatic hydrolysate of oyster (Saccostrea cucullata). Biomed Prev Nutr. 2014; 4(3):343–53. doi:10.1016/j.bionut.2014.04.006
   Google Scholar
• Chalamaiah M, Jyothirmayi T, Diwan PV, Dinesh Kumar B. Antiproliferative, ACE-inhibitory and functional properties of protein hydrolysates from rohu (Labeo rohita) roe (egg) prepared by gastrointestinal proteases. J Food Sci Technol. 2015; 52(12):8300–7. doi:10.1007/s13197-015-1969-y
   PubMed Web of Science ®Google Scholar
• Chi C-F, Hu F-Y, Wang B, Li T, Ding G-F. Antioxidant and anticancer peptides from the protein hydrolysate of blood clam (Tegillarca granosa) muscle. J Funct Foods. 2015; 15:301–13. doi:10.1016/j.jff.2015.03.045
   Web of Science ®Google Scholar
• Su L, Shi Y, Yan M, Xi Y, Su X. Anticancer bioactive peptides suppress human colorectal tumor cell growth and induce apoptosis via modulating the PARP-p53-Mcl-1 signaling pathway. Acta Pharmacol Sin. 2015; 36(12):1514–9. doi:10.1038/aps.2015.80
   PubMed Web of Science ®Google Scholar
• Xue Z, Wen H, Zhai L, Yu Y, Li Y, Yu W, Cheng A, Wang C, Kou X. Antioxidant activity and anti-proliferative effect of a bioactive peptide from chickpea (Cicer arietinum L.). Food Res Int. 2015; 77:75–81. doi:10.1016/j.foodres.2015.09.027
   Web of Science ®Google Scholar
• Zheng Q, Qiu D, Liu X, Zhang L, Cai S, Zhang X. Antiproliferative effect of Dendrobium catenatum Lindley polypeptides against human liver, gastric and breast cancer cell lines. Food Funct. 2015; 6(5):1489–95. doi:10.1039/c5fo00060b
   PubMed Web of Science ®Google Scholar
• Shi D, Hou X, Wang L, Gao Y, Wu D, Xi X, Zhou M, Kwok H, Duan J, Chen T, et al. Two Novel Dermaseptin-Like Antimicrobial Peptides with Anticancer Activities from the Skin Secretion of Pachymedusa dacnicolor. Toxins. 2016; 8(5):144. doi:10.3390/toxins8050144
   PubMed Web of Science ®Google Scholar
• Theansungnoen T, Maijaroen S, Jangpromma N, Yaraksa N, Daduang S, Temsiripong T, Daduang J, Klaynongsruang S. Cationic antimicrobial peptides derived from crocodylus siamensis leukocyte extract, revealing anticancer activity and apoptotic induction on human cervical cancer cells. Protein J. 2016; 35(3):202–11. doi:10.1007/s10930-016-9662-1
   PubMed Web of Science ®Google Scholar
• Yang J-I, Tang J-Y, Liu Y-S, Wang H-R, Lee S-Y, Yen C-Y, Chang H-W. Roe protein hydrolysates of giant grouper (epinephelus lanceolatus) inhibit cell proliferation of oral cancer cells involving apoptosis and oxidative stress. Biomed Res Int. 2016; 2016:8305073–12. doi:10.1155/2016/8305073
   PubMed Web of Science ®Google Scholar
• Sae-Leaw T, O'Callaghan YC, Benjakul S, O'Brien NM. Antioxidant, immunomodulatory and antiproliferative effects of gelatin hydrolysates from seabass (Lates calcarifer) skins. Int J Food Sci Technol. 2016; 51(7):1545–51. doi:10.1111/ijfs.13123
   Web of Science ®Google Scholar
• Wang L, Zhang J, Yuan Q, Xie H, Shi J, Ju X. Separation and purification of an anti-tumor peptide from rapeseed (Brassica campestris L.) and the effect on cell apoptosis. Food Funct. 2016; 7(5):2239–48. doi:10.1039/c6fo00042h
   PubMed Web of Science ®Google Scholar
• Pan X, Zhao Y-Q, Hu F-Y, Chi C-F, Wang B. anticancer activity of a hexapeptide from skate (raja porosa) cartilage protein hydrolysate in HeLa cells. Mar Drugs. 2016; 14(8):153. doi:10.3390/md14080153
   PubMed Web of Science ®Google Scholar
• Wang Z, Zhang X. Isolation and identification of anti-proliferative peptides fromSpirulina platensisusing three-step hydrolysis. J Sci Food Agric. 2017; 97(3):918–22. doi:10.1002/jsfa.7815
   PubMed Web of Science ®Google Scholar
• Sun Y, Hu X, Li W. Antioxidant, antitumor and immunostimulatory activities of the polypeptide from Pleurotus eryngii mycelium. Int J Biol Macromol. 2017; 97:323–30. doi:10.1016/j.ijbiomac.2017.01.043
   PubMed Web of Science ®Google Scholar
• Tada N, Horibe T, Haramoto M, Ohara K, Kohno M, Kawakami K. A single replacement of histidine to arginine in EGFR-lytic hybrid peptide demonstrates the improved anticancer activity. Biochem Biophys Res Commun. 2011; 407(2):383–8. doi:10.1016/j.bbrc.2011.03.030
   PubMed Web of Science ®Google Scholar
• JumeriKim SM. Antioxidant and anticancer activities of enzymatic hydrolysates of solitary tunicate (Styela clava). Food Sci Biotechnol. 2011; 20(4):1075–85. doi:10.1007/s10068-011-0146-y
   Web of Science ®Google Scholar
• Broere F, Apasov SG, Sitkovsky MV, Eden V. W. A2 T cell subsets and T cell-mediated immunity. In: Principles of Immunopharmacology. Basel: Birkhäuser; 2011. 15–27. doi:10.1007/978-3-0346-0136-8_2
   Google Scholar
• Wang Y-K, He H-L, Wang G-F, Wu H, Zhou B-C, Chen X-L, Zhang Y-Z. Oyster (Crassostrea gigas) hydrolysates produced on a plant scale have antitumor activity and immunostimulating effects in BALB/c mice. Mar Drugs. 2010; 8(2):255–68. doi:10.3390/md8020255
   PubMed Web of Science ®Google Scholar
• Chalamaiah M, Hemalatha R, Jyothirmayi T, Diwan PV, Uday Kumar P, Nimgulkar C, Dinesh Kumar B. Immunomodulatory effects of protein hydrolysates from Rohu (Labeo rohita) egg (roe) in BALB/c mice. Food Res Int. 2014;62:1054–61. doi:10.1016/j.foodres.2014.05.050
   Web of Science ®Google Scholar
• Mallet J-F, Duarte J, Vinderola G, Anguenot R, Beaulieu M, Matar C. The immunopotentiating effects of shark-derived protein hydrolysate. Nutrition. 2014; 30(6):706–12. doi:10.1016/j.nut.2013.10.025
   PubMed Web of Science ®Google Scholar
• Chalamaiah M, Hemalatha R, Jyothirmayi T, Diwan PV, Bhaskarachary K, Vajreswari A, Ramesh Kumar R, Dinesh Kumar B. Chemical composition and immunomodulatory effects of enzymatic protein hydrolysates from common carp (Cyprinus carpio) egg. Nutrition. 2015; 31(2):388–98. doi:10.1016/j.nut.2014.08.006
   PubMed Web of Science ®Google Scholar
• Ahn C-B, Cho Y-S, Je J-Y. Purification and anti-inflammatory action of tripeptide from salmon pectoral fin byproduct protein hydrolysate. Food Chem. 2015; 168:151–6. doi:10.1016/j.foodchem.2014.05.112
   PubMed Web of Science ®Google Scholar
• Karnjanapratum S, O'Callaghan YC, Benjakul S, O'Brien N. Antioxidant, immunomodulatory and antiproliferative effects of gelatin hydrolysate from unicorn leatherjacket skin. J Sci Food Agric. 2016; 96(9):3220–6. doi:10.1002/jsfa.7504
   PubMed Web of Science ®Google Scholar
• Hou H, Fan Y, Wang S, Si L, Li B. Immunomodulatory activity of Alaska pollock hydrolysates obtained by glutamic acid biosensor – Artificial neural network and the identification of its active central fragment. J Funct Foods. 2016; 24:37–47. doi:10.1016/j.jff.2016.03.033
   Web of Science ®Google Scholar
• Ma J-J, Mao X-Y, Wang Q, Yang S, Zhang D, Chen S-W, Li Y-H. Effect of spray drying and freeze drying on the immunomodulatory activity, bitter taste and hygroscopicity of hydrolysate derived from whey protein concentrate. LWT Food Sci Technol. 2014; 56(2):296–302. doi:10.1016/j.lwt.2013.12.019
   Web of Science ®Google Scholar
• Rodríguez-Carrio J, Fernández A, Riera FA, Suárez A. Immunomodulatory activities of whey β-lactoglobulin tryptic-digested fractions. Int Dairy J. 2014; 34(1):65–73. doi:10.1016/j.idairyj.2013.07.004
   Web of Science ®Google Scholar
• Montoya-Rodríguez A, de Mejía EG, Dia VP, Reyes-Moreno C, Milán-Carrillo J. Extrusion improved the anti-inflammatory effect of amaranth (Amaranthus hypochondriacus) hydrolysates in LPS-induced human THP-1 macrophage-like and mouse RAW 264.7 macrophages by preventing activation of NF-κB signaling. Mol Nutr Food Res. 2014; 58(5):1028–41. doi:10.1002/mnfr.201300764
   PubMed Web of Science ®Google Scholar
• Lozano-Ojalvo D, Molina E, López-Fandiño R. Hydrolysates of egg white proteins modulate T- and B-cell responses in mitogen-stimulated murine cells. Food Funct. 2016; 7(2):1048–56. doi:10.1039/c5fo00614g
   PubMed Web of Science ®Google Scholar
• Xu Z, Mao T-M, Huang L, Yu Z-C, Yin B, Chen M-L, Cheng Y-H. Purification and identification immunomodulatory peptide from rice protein hydrolysates. Food Agric Immunol. 2019; 30(1):150–62. doi:10.1080/09540105.2018.1553938
   Web of Science ®Google Scholar
• Ling-Ling L, Bin L, Hui-Fang J, Qun M, Ling-Zhi W. Immunomodulatory activity of small molecular (≤3 kDa) Coix glutelin enzymatic hydrolysate. CyTA J Food. 2016; 15(1):1–48. doi:10.1080/19476337.2016.1201147
   Web of Science ®Google Scholar
• Millán-Linares M, del C, Bermúdez B, Yust M, del M, Millán F, Pedroche J. Anti-inflammatory activity of lupine (Lupinus angustifolius L.) protein hydrolysates in THP-1-derived macrophages. J Funct Foods. 2014;8:224–33. doi:10.1016/j.jff.2014.03.020
   Web of Science ®Google Scholar
• Huang D, Yang L, Wang C, Ma S, Cui L, Huang S, Sheng X, Weng Q, Xu M. Immunostimulatory activity of protein hydrolysate from oviductus ranae on macrophage in vitro. Evid Based Complement Alternat Med. 2014; 2014:180234–11. doi:10.1155/2014/180234
   PubMed Web of Science ®Google Scholar
• He XQ, Cao WH, Pan GK, Yang L, Zhang CH. Enzymatic hydrolysis optimization of Paphia undulata and lymphocyte proliferation activity of the isolated peptide fractions. J Sci Food Agric. 2015; 95(7):1544–53. doi:10.1002/jsfa.6859
   PubMed Web of Science ®Google Scholar
• Toopcham T, Mes JJ, Wichers HJ, Yongsawatdigul J. Immunomodulatory activity of protein hydrolysates derived from Virgibacillus halodenitrificans SK1-3-7 proteinase. Food Chem. 2017; 224:320–8. doi:10.1016/j.foodchem.2016.12.041
   PubMed Web of Science ®Google Scholar
• Meram C, Wu J. Anti-inflammatory effects of egg yolk livetins (α, β, and γ-livetin) fraction and its enzymatic hydrolysates in lipopolysaccharide-induced RAW 264.7 macrophages. Food Res Int. 2017; 100:449–59. doi:10.1016/j.foodres.2017.07.032
   PubMed Web of Science ®Google Scholar
• Chan-Zapata I, Arana-Argáez VE, Torres-Romero JC, Segura-Campos MR. Anti-inflammatory effects of the protein hydrolysate and peptide fractions isolated from Salvia hispanica L. seeds. Food Agric Immunol. 2019; 30(1):786–803. doi:10.1080/09540105.2019.1632804
   Web of Science ®Google Scholar
• Laviada‐Castillo RE, Segura‐Campos MR, Chan‐Zapata I, Torres‐Romero JC, Guillermo‐Cordero JL, Arana‐Argáez VE. Immunosuppressive effects of protein derivatives from Mucuna pruriens on a streptozotocin‐induced type 1 diabetes murine model. J Food Biochem. 2019;43(5):e12834. doi:10.1111/jfbc.12834
   PubMed Web of Science ®Google Scholar
• Wu W, Zhang M, Sun C, Brennan M, Li H, Wang G, Lai F, Wu H. Enzymatic preparation of immunomodulatory hydrolysates from defatted wheat germ (Triticum Vulgare) globulin. Int J Food Sci Technol. 2016; 51(12):2556–66. doi:10.1111/ijfs.13238
   Web of Science ®Google Scholar
• Vogel HJ, Schibli DJ, Jing W, Lohmeier-Vogel EM, Epand RF, Epand RM. Towards a structure-function analysis of bovine lactoferricin and related tryptophan- and arginine-containing peptides. Biochem Cell Biol. 2002; 80(1):49–63. doi:10.1139/o01-213
   PubMed Web of Science ®Google Scholar
• Wagle JR, Ansevin AT, Dessens SE, Nishioka K. Specific translocation of tuftsin (Thr-Lys-Pro-Arg), a natural immunomodulating peptide, into the nuclei of human monocytes. Biochem Biophys Res Commun. 1989; 159(3):1147–53. doi:10.1016/0006-291X(89)92229-8
   PubMed Web of Science ®Google Scholar
• Lau JL, Dunn MK. Therapeutic peptides: Historical perspectives, current development trends, and future directions. Bioorg Med Chem. 2018;26(10):2700–7. doi:10.1016/j.bmc.2017.06.052
   PubMed Web of Science ®Google Scholar
• Felício MR, Silva ON, Gonçalves S, Santos NC, Franco OL. Peptides with dual antimicrobial and anticancer activities. Front Chem. 2017;5:5doi:10.3389/fchem.2017.00005
   PubMed Web of Science ®Google Scholar
• Renukuntla J, Vadlapudi AD, Patel A, Boddu SHS, Mitra AK. Approaches for enhancing oral bioavailability of peptides and proteins. Int J Pharm. 2013;447(1-2):75–93. doi:10.1016/j.ijpharm.2013.02.030
   PubMed Web of Science ®Google Scholar
• Wang L, Dong C, Li X, Han W, Su X. Anticancer potential of bioactive peptides from animal sources (Review). Oncol Rep. 2017;38(2):637–51. doi:10.3892/or.2017.5778
   PubMed Web of Science ®Google Scholar
• Wu D, Gao Y, Qi Y, Chen L, Ma Y, Li Y. Peptide-based cancer therapy: Opportunity and challenge. Cancer Lett. 2014;351(1):13–22. doi:10.1016/j.canlet.2014.05.002
   PubMed Web of Science ®Google Scholar
• Matsuo AL, Juliano MA, Figueiredo CR, Batista WL, Tanaka AS, Travassos LR. A new phage-display tumor-homing peptide fused to antiangiogenic peptide generates a novel bioactive molecule with antimelanoma activity. Mol Cancer Res. 2011;9(11):1471–8. ‐ doi:10.1158/1541-7786.MCR-10-0501
   PubMed Web of Science ®Google Scholar
• Marqus S, Pirogova E, Piva TJ. Evaluation of the use therapeutic peptides for cancer treatment. J Biomed Sci. 2017; 24(1):21 doi:10.1186/s12929-017-0328-x
   PubMed Web of Science ®Google Scholar
• Fisher E, Pavlenko K, Vlasov A, Ramenskaya G. Peptide-based therapeutics for oncology. Pharm Med. 2019;33(1):9–20. doi:10.1007/s40290-018-0261-7
   PubMed Web of Science ®Google Scholar
• McGregor DP. Discovering and improving novel peptide therapeutics. Curr Opin Pharmacol. 2008; 8(5):616–9. doi:10.1016/j.coph.2008.06.002
   PubMed Web of Science ®Google Scholar
• Berkowitz SA, Engen JR, Mazzeo JR, Jones GB. Analytical tools for characterizing biopharmaceuticals and the implications for biosimilars. Nat Rev Drug Discov. 2012;11(7):527–40. doi:10.1038/nrd3746
   PubMed Web of Science ®Google Scholar
• Chakrabarti S, Guha S, Majumder K. Food-Derived Bioactive Peptides in Human Health: Challenges and Opportunities. Nutrients. 2018; 10(11):1738. doi:10.3390/nu10111738
   PubMed Web of Science ®Google Scholar