The Anti-Tumor Effects of Oenothera odorata Extract Are Mediated by Inhibition of Glycolysis and Cellular Respiration in Cancer Cells

References

• Hoelder S, Clarke PA, Workman P. Discovery of small molecule cancer drugs: successes, challenges and opportunities. Mol Oncol. 2012;6(2):155–176. doi:https://doi.org/10.1016/j.molonc.2012.02.004
   PubMed Web of Science ®Google Scholar
• Coussens NP, Braisted JC, Peryea T, Sittampalam GS, Simeonov A, Hall MD. Small-molecule screens: a gateway to cancer therapeutic agents with case studies of food and drug administration-approved drugs. Pharmacol Rev. 2017;69(4):479–496. doi:https://doi.org/10.1124/pr.117.013755
   PubMed Web of Science ®Google Scholar
• Ferlay J, Soerjomataram I, Dikshit R, Eser S, Mathers C, Rebelo M, Parkin DM, Forman D, Bray F. Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. Int J Cancer. 2015;136(5):E359–E386. doi:https://doi.org/10.1002/ijc.29210
   PubMed Web of Science ®Google Scholar
• Siegel RL, Miller KD, Jemal A. Cancer statistics, 2016. CA Cancer J Clin. 2016;66(1):7–30. doi:https://doi.org/10.3322/caac.21332
   PubMed Web of Science ®Google Scholar
• Mishra BB, Tiwari VK. Natural products: an evolving role in future drug discovery. Eur J Med Chem. 2011;46(10):4769–4807. doi:https://doi.org/10.1016/j.ejmech.2011.07.057
   PubMed Web of Science ®Google Scholar
• Alves-Silva JM, Romane A, Efferth T, Salgueiro L. North African medicinal plants traditionally used in cancer therapy. Front Pharmacol. 2017;8:383. doi:https://doi.org/10.3389/fphar.2017.00383
   PubMed Web of Science ®Google Scholar
• Tariq A, Sadia S, Pan K, Ullah I, Mussarat S, Sun F, Abiodun OO, Batbaatar A, Li Z, Song D, et al. A systematic review on ethnomedicines of anti-cancer plants. Phytother Res. 2017;31(2):202–264. doi:https://doi.org/10.1002/ptr.5751
   PubMed Web of Science ®Google Scholar
• Nwodo JN, Ibezim A, Simoben CV, Ntie-Kang F. Exploring cancer therapeutics with natural products from african medicinal plants, part ii: alkaloids, terpenoids and flavonoids. Anticancer Agents Med Chem. 2016;16(1):108–127. doi:https://doi.org/10.2174/1871520615666150520143827
   PubMed Web of Science ®Google Scholar
• Sharma M, Agrawal SK, Sharma PR, Chadha BS, Khosla MK, Saxena AK. Cytotoxic and apoptotic activity of essential oil from Ocimumviride towards COLO 205 cells. Food Chem Toxicol. 2010;48(1):336–344. doi:https://doi.org/10.1016/j.fct.2009.10.021
   PubMed Web of Science ®Google Scholar
• Katz L, Baltz RH. Natural product discovery: past, present, and future. J Ind Microbiol Biotechnol. 2016;43(2–3):155–176. doi:https://doi.org/10.1007/s10295-015-1723-5
   PubMed Web of Science ®Google Scholar
• Bernardini S, Tiezzi A, Laghezza Masci V, Ovidi E. Natural products for human health: an historical overview of the drug discovery approaches. Nat Prod Res. 2018;32(16):1926–1950. doi:https://doi.org/10.1080/14786419.2017.1356838
   PubMed Web of Science ®Google Scholar
• Newman DJ, Cragg GM. Natural products as sources of new drugs from 1981 to 2014. J Nat Prod. 2016;79(3):629–661. doi:https://doi.org/10.1021/acs.jnatprod.5b01055
   PubMed Web of Science ®Google Scholar
• Guo Z. The modification of natural products for medical use. Acta Pharm Sin B. 2017;7(2):119–136. doi:https://doi.org/10.1016/j.apsb.2016.06.003
   PubMed Web of Science ®Google Scholar
• Yao H, Liu J, Xu S, Zhu Z, Xu J. The structural modification of natural products for novel drug discovery. Expert Opin Drug Discov. 2017;12(2):121–140. doi:https://doi.org/10.1080/17460441.2016.1272757
   PubMed Web of Science ®Google Scholar
• Horrobin DF. Nutritional and medical importance of gamma-linolenic acid. Prog Lipid Res. 1992;31(2):163–194. doi:https://doi.org/10.1016/0163-7827(92)90008-7
   PubMed Web of Science ®Google Scholar
• Jack AM, Keegan A, Cotter MA, Cameron NE. Effects of diabetes and evening primrose oil treatment on responses of aorta, corpus cavernosum and mesenteric vasculature in rats. Life Sci. 2002;71(16):1863–1877. doi:https://doi.org/10.1016/s0024-3205(02)01912-4
   PubMedGoogle Scholar
• Kim GY, Lee YM, Kwon JH, Jun HS, Chou J. Glycogen storage disease type Ib neutrophils exhibit impaired cell adhesion and migration. Biochem Biophys Res Commun. 2017;482(4):569–74. doi:https://doi.org/10.1016/j.bbrc.2016.11.075
   PubMedGoogle Scholar
• Van den Bossche J, Baardman J, de Winther MP. Metabolic characterization of polarized M1 and M2 bone marrow-derived macrophages using real-time extracellular flux analysis. J Vis Exp. 2015;105:e53424. doi:https://doi.org/10.3791/53424
   Google Scholar
• Koppenol WH, Bounds PL, Dang CV. Otto Warburg's contributions to current concepts of cancer metabolism. Nat Rev Cancer. 2011;11(5):325–337. doi:https://doi.org/10.1038/nrc3038
   PubMed Web of Science ®Google Scholar
• Alfarouk KO. Tumor metabolism, cancer cell transporters, and microenvironmental resistance. J Enzyme Inhib Med Chem. 2016;31(6):859–866. doi:https://doi.org/10.3109/14756366.2016.1140753
   PubMed Web of Science ®Google Scholar
• Hevesi Toth B, Blazics B, Kery A. Polyphenol composition and antioxidant capacity of Epilobium species. J Pharm Biomed Anal. 2009;49(1):26–31. doi:https://doi.org/10.1016/j.jpba.2008.09.047
   PubMedGoogle Scholar
• Basu A, Krishnamurthy S. Cellular responses to Cisplatin-induced DNA damage. J Nucleic Acids. 2010;2010:1–16. doi:https://doi.org/10.4061/2010/201367
   Google Scholar
• Giard DJ, Aaronson SA, Todaro GJ, Arnstein P, Kersey JH, Dosik H, Parks WP. In vitro cultivation of human tumors: establishment of cell lines derived from a series of solid tumors. J Natl Cancer Inst. 1973;51(5):1417–1423. doi:https://doi.org/10.1093/jnci/51.5.1417
   PubMedGoogle Scholar
• Zhao F, Klimecki WT. Culture conditions profoundly impact phenotype in BEAS-2B, a human pulmonary epithelial model. J Appl Toxicol. 2015;35(8):945–951. doi:https://doi.org/10.1002/jat.3094
   PubMed Web of Science ®Google Scholar
• Hwang E, Sim S, Park SH, Song KD, Lee H-K, Heo T-H, Jun HS, Kim S-J. Anti-proliferative effect of Zea mays L. cob extract on rat C6 glioma cells through regulation of glycolysis, mitochondrial ROS, and apoptosis. Biomed Pharmacother. 2018;98:726–732. doi:https://doi.org/10.1016/j.biopha.2017.12.115
   PubMedGoogle Scholar
• Oberoi HS, Nukolova NV, Laquer FC, Poluektova LY, Huang J, Alnouti Y, Yokohira M, Arnold LL, Kabanov AV, Cohen SM, et al. Cisplatin-loaded core cross-linked micelles: comparative pharmacokinetics, antitumor activity, and toxicity in mice. Int J Nanomed. 2012;7:2557–2571. doi:https://doi.org/10.2147/IJN.S29145
   PubMed Web of Science ®Google Scholar
• Tadagavadi RK, Gao G, Wang WW, Gonzalez MR, Reeves WB. Dendritic cell protection from cisplatin nephrotoxicity is independent of neutrophils. Toxins (Basel). 2015;7(8):3245–56. doi:https://doi.org/10.3390/toxins7083245
   PubMed Web of Science ®Google Scholar
• Gali-Muhtasib H, Hmadi R, Kareh M, Tohme R, Darwiche N. Cell death mechanisms of plant-derived anticancer drugs: beyond apoptosis. Apoptosis. 2015;20(12):1531–1562. doi:https://doi.org/10.1007/s10495-015-1169-2
   PubMed Web of Science ®Google Scholar
• Nahata A, Saxena A, Suri N, Saxena AK, Dixit VK. Sphaeranthus indicus induces apoptosis through mitochondrial-dependent pathway in HL-60 cells and exerts cytotoxic potential on several human cancer cell lines. Integr Cancer Ther. 2013;12(3):236–47. doi:https://doi.org/10.1177/1534735412451997
   PubMedGoogle Scholar