References
- Rawla P, Sunkara T, Barsouk A. Epidemiology of colorectal cancer: Incidence, mortality, survival, and risk factors. Prz Gastroenterol. 2019;14(2):89–103. doi:https://doi.org/10.5114/pg.2018.81072
- Hong Y, Rao Y. Current status of nanoscale drug delivery systems for colorectal cancer liver metastasis. Biomed Pharmacother. 2019;114:108764 doi:https://doi.org/10.1016/j.biopha.2019.108764
- Padma VV. An overview of targeted cancer therapy. Biomedicine (Taipei)). 2015;5(4):19 doi:https://doi.org/10.7603/s40681-015-0019-4
- Jain V, Jain S, Mahajan S. Nanomedicines based drug delivery systems for anti-cancer targeting and treatment. Curr Drug Deliv. 2015;12(2):177–91. doi:https://doi.org/10.2174/1567201811666140822112516
- Sánchez-López E, Guerra M, Dias-Ferreira J, Lopez-Machado A, Ettcheto M, Cano A, Espina M, Camins A, Garcia ML, Souto EB. Current applications of nanoemulsions in cancer therapeutics. Nanomaterials. 2019;9(6):821. doi:https://doi.org/10.3390/nano9060821
- Huang R-FS, Wei Y-J, Inbaraj BS, Chen B-H. Inhibition of colon cancer cell growth by nanoemulsion carrying gold nanoparticles and lycopene. Int J Nanomedicine. 2015;10:2823–46. doi:https://doi.org/10.2147/IJN.S79107
- Zhu Z, Min T, Zhang X, Wen Y. Microencapsulation of thymol in poly (lactide-co-glycolide)(PLGA): physical and antibacterial properties. Materials. 2019;12(7):1133. doi:https://doi.org/10.3390/ma12071133
- Kooti W, Servatyari K, Behzadifar M, Asadi-Samani M, Sadeghi F, Nouri B, Zare Marzouni H. Effective medicinal plant in cancer treatment, part 2: review study. J Evid Based Complement Altern Med. 2017;22(4):982–95. doi:https://doi.org/10.1177/2156587217696927
- Al-Menhali A, Al-Rumaihi A, Al-Mohammed H, Al-Mazrooey H, Al-Shamlan M, AlJassim M, Al-Korbi N, Eid AH. Thymus vulgaris (thyme) inhibits proliferation, adhesion, migration, and invasion of human colorectal cancer cells. J Med Food. 2015;18(1):54–9. doi:https://doi.org/10.1089/jmf.2013.3121
- Bairwa R, Sodha R, Rajawat B. Trachyspermum ammi. Pharmacogn Rev. 2012;6(11):56–60. doi:https://doi.org/10.4103/0973-7847.95871
- Danhier F, Ansorena E, Silva JM, Coco R, Breton AL, Préat V. PLGA-based nanoparticles: an overview of biomedical applications. J Control Release. 2012;161(2) 505–22. doi:https://doi.org/10.1016/j.jconrel.2012.01.043
- Pistritto G, Trisciuoglio D, Ceci C, Garufi A, D'Orazi G. Apoptosis as anticancer mechanism: function and dysfunction of its modulators and targeted therapeutic strategies. Aging (Albany NY)). 2016;8(4):603–19. doi:https://doi.org/10.18632/aging.100934
- Sznarkowska A, Kostecka A, Meller K, Bielawski KP. Inhibition of cancer antioxidant defense by natural compounds. Oncotarget. 2017;8(9):15996–6016. doi:https://doi.org/10.18632/oncotarget.13723
- Rajasekar J, Perumal MK, Vallikannan B. A critical review on anti-angiogenic property of phytochemicals. J Nutr Biochem. 2019;71:1–15. doi:https://doi.org/10.1016/j.jnutbio.2019.04.006
- Hafezi Ghahestani Z, Alebooye Langroodi F, Mokhtarzadeh A, Ramezani M, Hashemi M. Evaluation of anti-cancer activity of PLGA nanoparticles containing crocetin. Artif Cells Nanomed Biotechnol. 2017;45(5):955–60. doi:https://doi.org/10.1080/21691401.2016.1198359
- Benzie IF, Strain JJ. The ferric reducing ability of plasma (FRAP) as a measure of “antioxidant power”: the FRAP assay. Anal Biochem. 1996;239(1):70–6. doi:https://doi.org/10.1006/abio.1996.0292
- Rajurkar NS, Hande S. Estimation of phytochemical content and antioxidant activity of some selected traditional Indian medicinal plants. Indian J Pharm Sci. 2011;73(2):146–51. doi:https://doi.org/10.4103/0250-474x.91574
- Li P, Huo L, Su W, Lu R, Deng C, Liu L, Deng Y, Guo N, Lu C, He C. Free radical-scavenging capacity, antioxidant activity and phenolic content of Pouzolzia zeylanica. J Serb Chem Soc. 2011;76(5):709–17. doi:https://doi.org/10.2298/JSC100818063L
- Sanaeimehr Z, Javadi I, Namvar F. Antiangiogenic and antiapoptotic effects of green-synthesized zinc oxide nanoparticles using Sargassum muticum algae extraction. Cancer Nanotechnol. 2018;9(1):3 doi:https://doi.org/10.1186/s12645-018-0037-5
- Stetefeld J, McKenna SA, Patel TR. Dynamic light scattering: a practical guide and applications in biomedical sciences. Biophys Rev. 2016;8(4):409–27. doi:https://doi.org/10.1007/s12551-016-0218-6
- Salopek B, Krasic D, Filipovic S. Measurement and application of zeta-potential. Rudarsko-geolosko-naftni zbornik. 1992;4(1):147.
- Ur Rashid H, Xu Y, Muhammad Y, Wang L, Jiang J. Research advances on anticancer activities of matrine and its derivatives: An updated overview. Eur J Med Chem. 2019;161(1):205–38. doi:https://doi.org/10.1016/j.ejmech.201.10.037
- Reza KH. Nanoemulsion as a novel transdermal drug delivery system. Int J Pharm Sci Res. 2011;2(8):1938.
- Ashfaq UA, Riaz M, Yasmeen E, Yousaf MZ. Recent advances in nanoparticle-based targeted drug-delivery systems against cancer and role of tumor microenvironment. Crit Rev™ Therapeut Drug Carrier Syst. 2017;34(4):317–353.
- Cragg GM, Newman DJ. Plants as a source of anti-cancer agents. J Ethnopharmacol. 2005;100(1-2):72–9. doi:https://doi.org/10.1016/j.jep.2005.05.011
- Fazelifar P, Tabrizi MH, Rafiee A. The Arachis hypogaea essential oil nanoemulsion as an efficient safe apoptosis inducer in human lung cancer cells (A549). Nutrition and Cancer. 2020;25(6):1–9.
- Khatamian N, Homayouni Tabrizi M, Ardalan P, Yadamani S, Darchini Maragheh A. Synthesis of Carum Carvi essential oil nanoemulsion, the cytotoxic effect, and expression of caspase 3 gene. J Food Biochem. 2019;43(8):e12956. doi:https://doi.org/10.1111/jfbc.12956
- Maragheh AD, Tabrizi MH, Karimi E, Seyedi SMR, Khatamian N. Producing the sour cherry pit oil nanoemulsion and evaluation of its anti-cancer effects on both breast cancer murine model and MCF-7 cell line. J Microencapsul. 2019;36(4):399–409. doi:https://doi.org/10.1080/02652048.2019.1638460
- Naeim P, Ahari H, Ataei M. Study of the antifungal effects of nanoemulsion and essential oils of Trachyspermum ammi on the Aspergillus niger and the survey of it, s antioxidant effects on shelf life of hamburger. J Comparat Pathobiol. 2019;16(1):2777–2786.
- Tabatabai MB, Mirjalili M, Yazdiyan F, Hekmatimoghaddam S. Antibacterial activity and cytotoxicity of nanoliposomic and nanoniosomic essential oil of Trachyspermum copticum. Proc Natl Acad Sci, India, Sect B Biol Sci. 2019;89(3):1109–16. doi:https://doi.org/10.1007/s40011-018-1025-6
- Sivropoulou A, Papanikolaou E, Nikolaou C, Kokkini S, Lanaras T, Arsenakis M. Antimicrobial and cytotoxic activities of origanum essential oils. J Agric Food Chem. 1996;44(5):1202–5. doi:https://doi.org/10.1021/jf950540t
- Valenti D, De Logu A, Loy G, Sinico C, Bonsignore L, Cottiglia F, Garau D, Fadda AM. Liposome-incorporated Santolina insularis essential oil: preparation, characterization and in vitro antiviral activity. J Liposome Res. 2001;11(1):73–90. doi:https://doi.org/10.1081/LPR-100103171
- Dawane JS, Pandit VA. Understanding redox homeostasis and its role in cancer. J Clin Diagn Res. 2012;6(10):1796–802. doi:https://doi.org/10.7860/JCDR/2012/4947.2654
- DeBerardinis RJ, Lum JJ, Hatzivassiliou G, Thompson CB. The biology of cancer: metabolic reprogramming fuels cell growth and proliferation. Cell Metab. 2008;7(1):11–20. doi:https://doi.org/10.1016/j.cmet.2007.10.002
- Zhao Y, Adjei AA. Targeting angiogenesis in cancer therapy: moving beyond vascular endothelial growth factor. Oncologist. 2015;20(6):660–73. doi:https://doi.org/10.1634/theoncologist.2014-0465
- Rice-Evans C, Miller N, Paganga G. Antioxidant properties of phenolic compounds. Trends Plant Sci. 1997;2(4):152–9. doi:https://doi.org/10.1016/S1360-1385(97)01018-2
- Botelho MA, Barros G, Queiroz DB, Carvalho CF, Gouvea J, Patrus L, Bannet M, Patrus D, Rego A, Silva I, et al. Nanotechnology in phytotherapy: antiinflammatory effect of a nanostructured thymol gel from Lippia sidoides in acute periodontitis in rats. Phytother Res. 2016;30(1):152–9. doi:https://doi.org/10.1002/ptr.5516
- Deng L, Taxipalati M, Sun P, Que F, Zhang H. Phase behavior, microstructural transition, antimicrobial and antioxidant activities of a water-dilutable thymol microemulsion. Colloids Surf B Biointerfaces. 2015;136:859–66. doi:https://doi.org/10.1016/j.colsurfb.2015.10.031
- Güvenç M, Cellat M, Gökçek İ, Yavaş İ, Yurdagül Özsoy Ş. Effects of thymol and carvacrol on sperm quality and oxidant/antioxidant balance in rats. Arch Physiol Biochem. 2019;125(5):396–403. doi:https://doi.org/10.1080/13813455.2018.1476979
- Skopychenko M. Thymol-veronal test in cancer of the internal organs. Med Zhurnal. 1954;24(2):88–91.
- Juret P. Prognostic significance of the thymol test of MacLagan in cancer of the breast. Its paradoxal fluctuations in the course of the development of the disease. in Ann Biol Clin. 1961;19(1):175–82.
- Salehi B, Zucca P, Sharifi‐Rad M, Pezzani R, Rajabi S, Setzer WN, Varoni EM, Iriti M, Kobarfard F, Sharifi‐Rad J. Phytotherapeutics in cancer invasion and metastasis. Phytother Res. 2018;32(8):1425–49. doi:https://doi.org/10.1002/ptr.6087
- Kang S-H, Kim Y-S, Kim E-K, Hwang J-W, Jeong J-H, Dong X, Lee J-W, Moon S-H, Jeon B-T, Park P-J. Anticancer effect of thymol on AGS human gastric carcinoma cells. J Microbiol Biotechnol. 2016;26(1):28–37. doi:https://doi.org/10.4014/jmb.1506.06073
- Islam MT, Khalipha AB, Bagchi R, Mondal M, Smrity SZ, Uddin SJ, Shilpi JA, Rouf R. Anticancer activity of thymol: A literature-based review and docking study with Emphasis on its anticancer mechanisms . IUBMB Life. 2019;71(1):9–19. doi:https://doi.org/10.1002/iub.1935
- Hou J, Zhang Y, Zhu Y, Zhou B, Ren C, Liang S, Guo Y. α-Pinene induces apoptotic cell death via caspase activation in human ovarian cancer cells. Med Sci Monit. 2019;25:6631–8. doi:https://doi.org/10.12659/MSM.916419
- da Silva JKR, Pinto LC, Burbano RM, Montenegro RC, Andrade EHA, Maia JGS. Composition and cytotoxic and antioxidant activities of the oil of Piper aequale Vahl. Lipids Health Dis. 2016;15(1):174. doi:https://doi.org/10.1186/s12944-016-0347-8
- Van Ba H, Hwang I. Role of caspase-9 in the effector caspases and genome expressions, and growth of bovine skeletal myoblasts. Dev Growth Differ. 2014;56(2):131–42. doi:https://doi.org/10.1111/dgd.12098
- Kulsoom B, Shamsi TS, Afsar NA, Memon Z, Ahmed N, Hasnain SN. Bax, Bcl-2, and Bax/Bcl-2 as prognostic markers in acute myeloid leukemia: are we ready for Bcl-2-directed therapy? CMAR. 2018;Volume 10:403–16. doi:https://doi.org/10.2147/CMAR.S154608
- Demirci F, Paper DH, Franz G, Başer KHC. Investigation of the Origanum onites L. essential oil using the chorioallantoic membrane (CAM) assay. J Agric Food Chem. 2004;52(2):251–4. doi:https://doi.org/10.1021/jf034850k