References
- Miller KD, Nogueira L, Mariotto AB, Rowland JH, Yabroff KR, Alfano CM, Jemal A, Kramer JL, Siegel RL. Cancer treatment and survivorship statistics, 2019. CA A Cancer J Clin. 2019;69(5):363–85. doi:https://doi.org/10.3322/caac.21565
- Noronha V, Patil VM, Joshi A, Menon N, Chougule A, Mahajan A, Janu A, Purandare N, Kumar R, More S, et al. Gefitinib versus gefitinib plus pemetrexed and carboplatin chemotherapy in EGFR-mutated lung cancer. J Clin Oncol. 2020;38(2):124–36. doi:https://doi.org/10.1200/JCO.19.01154
- Gao L, Li HR, Jin C, Jiang JH, Ding JY. Strategies to overcome acquired resistance to EGFR TKI in the treatment of non-small cell lung cancer. Clin Transl Oncol. 2019;21(10):1287–301. doi:https://doi.org/10.1007/s12094-019-02075-1
- Franek J, Cappelleri JC, Larkin-Kaiser KA, Wilner KD, Sandin R. Systematic review and network meta-analysis of first-line therapy for advanced EGFR-positive non-small-cell lung cancer. Future Oncol. 2019;15(24):2857–71. doi:https://doi.org/10.2217/fon-2019-0270
- Hou S-z, Xu S-j, Jiang D-x, Chen S-x, Wang L-l, Huang S, Lai X-p. Effect of the flavonoid fraction of Lithocarpus polystachyus Rehd. on spontaneously hypertensive and normotensive rats. J Ethnopharmacol. 2012;143(2):441–7. doi:https://doi.org/10.1016/j.jep.2012.06.016
- Wang J, Huang Y, Li K, Chen Y, Vanegas D, McLamore ES, Shen Y. Leaf extract from Lithocarpus polystachyus Rehd. promote glycogen synthesis in T2DM mice. PLoS One. 2016;11(11):e0166557. doi:https://doi.org/10.1371/journal.pone.0166557
- Sun Y, Li W, Liu Z. Preparative isolation, quantification and antioxidant activity of dihydrochalcones from sweet tea (Lithocarpus polystachyus Rehd). J Chromatogr B Analyt Technol Biomed Life Sci. 2015;1002:372–8. doi:https://doi.org/10.1016/j.jchromb.2015.08.045
- Fan X, Zhang Y, Dong H, Wang B, Ji H, Liu X. Trilobatin attenuates the LPS-mediated inflammatory response by suppressing the NF-κB signaling pathway. Food Chem. 2015;166:609–15. doi:https://doi.org/10.1016/j.foodchem.2014.06.022
- Wang L, Liu M, Yin F, Wang Y, Li X, Wu Y, Ye C, Liu J. Trilobatin, a novel SGLT1/1 inhibitor, selectively induces the proliferation of human hepatoblastoma cells. Molecules. 2019;24(18):3390. doi:https://doi.org/10.3390/molecules24183390
- Qin X, Xing YF, Zhou Z, Yao Y. Dihydrochalcone compounds isolated from crabapple leaves showed anticancer effects on human cancer cell lines. Molecules. 2015;20(12):21193–203. doi:https://doi.org/10.3390/molecules201219754
- Fei S-J, Zhang X-C, Dong S, Cheng H, Zhang Y-F, Huang L, Zhou H-Y, Xie Z, Chen Z-H, Wu Y-L, et al. Targeting mTOR to overcome epidermal growth factor receptor tyrosine kinase inhibitor resistance in non-small cell lung cancer cells. PLoS One. 2013;8(7):e69104. doi:https://doi.org/10.1371/journal.pone.0069104
- Zhou J, Hu Q, Zhang X, Zheng J, Xie B, Xu Z, Zhang W. Sensitivity to chemotherapeutics of NSCLC cells with acquired resistance to EGFR-TKIs is mediated by T790M mutation or epithelial-mesenchymal transition. Oncol Rep. 2018;39(4):1783–92. doi:https://doi.org/10.3892/or.2018.6242
- Zhang F, Wang J, Wang X, Wei N, Liu H, Zhang X. CD146-mediated acquisition of stemness phenotype enhances tumour invasion and metastasis after EGFR-TKI resistance in lung cancer. Clin Respir J. 2019;13(1):23–33. doi:https://doi.org/10.1111/crj.12976
- Wang Y, Lian YM, Ge CY. MiR-145 changes sensitivity of non-small cell lung cancer to gefitinib through targeting ADAM19. Eur Rev Med Pharmacol Sci. 2019;23:5831–9.
- Zhang W, Dong Y-Z, Du X, Peng X-N, Shen Q-M. MiRNA-153-3p promotes gefitinib-sensitivity in non-small cell lung cancer by inhibiting ATG5 expression and autophagy. Eur Rev Med Pharmacol Sci. 2019;23(6):2444–52. doi:https://doi.org/10.26355/eurrev_201903_17391
- Tanner KG, Kyte J. Dimerization of the extracellular domain of the receptor for epidermal growth factor containing the membrane-spanning segment in response to treatment with epidermal growth factor. J Biol Chem. 1999;274(50):35985–90. doi:https://doi.org/10.1074/jbc.274.50.35985
- Li Y-Q, Liu Y-S, Ying X-W, Zhou H-B, Wang Z, Wu S-C, Yan J-P, Jing Y-T, Yang Y. Lentivirus-mediated disintegrin and metalloproteinase 17 RNA interference reversed the acquired resistance to gefitinib in lung adenocarcinoma cells in vitro. Biotechnol Prog. 2018;34(1):196–205. doi:https://doi.org/10.1002/btpr.2564
- Sun X, Kaufman PD. Ki-67: more than a proliferation marker. Chromosoma. 2018;127(2):175–86. doi:https://doi.org/10.1007/s00412-018-0659-8
- Pathmanathan N, Balleine RL. Ki67 and proliferation in breast cancer. J Clin Pathol. 2013;66(6):512–6. doi:https://doi.org/10.1136/jclinpath-2012-201085
- Farooqi AA, Qureshi MZ, Khalid S, Attar R, Martinelli C, Sabitaliyevich UY, Nurmurzayevich SB, Taverna S, Poltronieri P, Xu B, et al. Regulation of cell signaling pathways by berberine in different cancers: searching for missing pieces of an incomplete jig-saw puzzle for an effective cancer therapy. Cancers (Basel). 2019;11(4):478. doi:https://doi.org/10.3390/cancers11040478
- Shangguan W-J, Li H, Zhang Y-H. Induction of G2/M phase cell cycle arrest and apoptosis by ginsenoside Rf in human osteosarcoma MG‑63 cells through the mitochondrial pathway. Oncol Rep. 2014;31(1):305–13. doi:https://doi.org/10.3892/or.2013.2815
- Zuo H-j, Liu S, Yan C, Li L-m, Pei X-f. In vitro and in vivo evaluation of antitumor activity of Ligustrum robustum, a Chinese herbal tea. Chin J Integr Med. 2019;25(6):425–30. doi:https://doi.org/10.1007/s11655-018-2983-5
- Radhika NK, Sreejith PS, Asha VV. Cytotoxic and apoptotic activity of Cheilanthes farinose (Forsk.) Kaulf. against human hepatoma, Hep3B cells. J Ethnopharmacol. 2010;128(1):166–71. doi:https://doi.org/10.1016/j.jep.2010.01.002
- Robertson JD, Orrenius S. Role of mitochondria in toxic cell death. Toxicology. 2002;181–182:491–6. doi:https://doi.org/10.1016/S0300-483X(02)00464-X
- Cui M, Zhang Y, Liu S, Xie W, Ji M, Lou H, Li X. 1-oxoeudesm-11(13)-ene-12, 8a-lactone-induced apoptosis via ROS generation and mitochondria activation in MCF-7 cells. Arch Pharm Res. 2011;34(8):1323–9. doi:https://doi.org/10.1007/s12272-011-0812-x
- Cory S, Adams JM. The Bcl2 family: regulators of the cellular life-or-death switch. Nat Rev Cancer. 2002;2(9):647–56. doi:https://doi.org/10.1038/nrc883
- Alam M, Takahashi R, Afify S, Oo A, Kumon K, Nawara H, Khayrani A, Du J, Zahra M, Seno A, et al. Exogenous crypto-1 suppresses self-renewal of cancer stem cell model. IJMS. 2018;19(11):3345. doi:https://doi.org/10.3390/ijms19113345
- Arrigoni E, Galimberti S, Petrini M, Danesi R, Paolo AD. ATP-binding cassette transmembrane transporters and their epigenetic control in cancer: an overview. Expert Opin Drug Metab Toxicol. 2016;12(12):1419–32. doi:https://doi.org/10.1080/17425255.2016.1215423
- Dai P-C, Liu D-L, Zhang L, Ye J, Wang Q, Zhang H-W, Lin X-H, Lai G-X. Astragaloside IV sensitizes non-small cell lung cancer cells to gefitinib potentially via regulation of SIRT6. Tumour Biol. 2017;39(4):101042831769755. doi:https://doi.org/10.1177/1010428317697555
- Han S-Y, Zhao W, Sun H, Zhou N, Zhou F, An G, Li P-P. Marsdenia tenacissima extract enhances gefitinib efficacy in non-small cell lung cancer xenografts. Phytomedicine. 2015;22(5):560–7. doi:https://doi.org/10.1016/j.phymed.2015.03.001
- Ko J-L, Lin C-H, Chen H-C, Hung W-H, Chien P-J, Chang H-Y, Wang B-Y. Effects and mechanisms of betulinic acid on improving EGFR TKI-resistance of lung cancer cells. Environ Toxicol. 2018;33(11):1153–9. doi:https://doi.org/10.1002/tox.22621
- Li F, Zhang J, Arfuso F, Chinnathambi A, Zayed ME, Alharbi SA, Kumar AP, Ahn KS, Sethi G. NF-κB in cancer therapy. Arch Toxicol. 2015;89(5):711–31. doi:https://doi.org/10.1007/s00204-015-1470-4
- Ji K, Sun X, Liu Y, Du L, Wang Y, He N, Wang J, Xu C, Liu Q. Regulation of apoptosis and radiation sensitization in lung cancer cells via the sirt1/NF-κB/Smac pathway. Cell Physiol Biochem. 2018;48(1):304–16. doi:https://doi.org/10.1159/000491730
- Wagner L, Marschall V, Karl S, Cristofanon S, Zobel K, Deshayes K, Vucic D, Debatin K-M, Fulda S. Smac mimetic sensitizes glioblastoma cells to temozolomide-induced apoptosis in a RIP1- and NF-κB-dependent manner. Oncogene. 2013;32(8):988–97. doi:https://doi.org/10.1038/onc.2012.108
- Zhang L, Chinnathambi A, Alharbi SA, Veeraraghavan VP, Mohan SK, Zhang G. Punicalagin promotes the apoptosis in human cervical cancer (ME-180) cells through mitochondrial pathway and by inhibiting the NF-kB signaling pathway. Saudi J Biol Sci. 2020;27(4):1100–6. doi:https://doi.org/10.1016/j.sjbs.2020.02.015
- Carolina GT, Javier GC, Karla VS, Edna AMT, Gisela CC, et al. NF-κB participates in the stem cell phenotype of ovarian cancer cells. Arch Med Res. 2017;48:343–51.