An Analysis of Environment-, Individual-, and Tumor-Related Factors Impacting Hypovitaminosis D in Patients with Malignant Tumors

References

• Pludowski P, Holick MF, Pilz S, Wagner CL, Hollis BW, Grant WB, Shoenfeld Y, Lerchbaum E, Llewellyn DJ, Kienreich K, et al. Vitamin D effects on musculoskeletal health, immunity, autoimmunity, cardiovascular disease, cancer, fertility, pregnancy, dementia and mortality-a review of recent evidence. Autoimmun Rev. 2013;12(10):976–89. doi:10.1016/j.autrev.2013.02.004.
   PubMed Web of Science ®Google Scholar
• Zmijewski MA. Vitamin D and human health. Int J Mol Sci. 2019;20(1):145. doi:10.3390/ijms20010145.
   PubMed Web of Science ®Google Scholar
• Lucock M, Jones P, Martin C, Yates Z, Veysey M, Furst J, Beckett E. Photobiology of vitamins. Nutr Rev. 2018;76(7):512–25. doi:10.1093/nutrit/nuy013.
   PubMed Web of Science ®Google Scholar
• Pludowski P, Holick MF, Grant WB, Konstantynowicz J, Mascarenhas MR, Haq A, Povoroznyuk V, Balatska N, Barbosa AP, Karonova T, et al. Vitamin D supplementation guidelines. J Steroid Biochem Mol Biol. 2018;175:125–35. doi:10.1016/j.jsbmb.2017.01.021.
   PubMed Web of Science ®Google Scholar
• Haq A, Wimalawansa SJ, Pludowski P, Anouti F. Clinical practice guidelines for vitamin D in the United Arab Emirates. J Steroid Biochem Mol Biol. 2018;175:4–11. doi:10.1016/j.jsbmb.2016.09.021.
   PubMed Web of Science ®Google Scholar
• Okazaki R, Ozono K, Fukumoto S, Inoue D, Yamauchi M, Minagawa M, Michigami T, Takeuchi Y, Matsumoto T, Sugimoto T, et al. Assessment criteria for vitamin D deficiency/insufficiency in Japan: Proposal by an expert panel supported by the research program of intractable diseases, Ministry of Health, Labour and Welfare, Japan, the Japanese society for bone and mineral research and the Japan Endocrine Society [Opinion]. J Bone Miner Metab. 2017;35(1):1–5. doi:10.1007/s00774-016-0805-4.
   PubMed Web of Science ®Google Scholar
• Holick MF, Binkley NC, Bischoff-Ferrari HA, Gordon CM, Hanley DA, Heaney RP, Murad MH, Weaver CM. Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2011;96(7):1911–30. doi:10.1210/jc.2011-0385.
   PubMed Web of Science ®Google Scholar
• Krist AH, Davidson KW, Mangione CM, Cabana M, Caughey AB, Davis EM, Donahue KE, Doubeni CA, Epling JW, Kubik M, US Preventive Services Task Force, et al. Screening for vitamin D deficiency in adults: US Preventive Services Task Force recommendation statement. JAMA. 2021;325(14):1436–42. doi:10.1001/jama.2021.3069.
   PubMed Web of Science ®Google Scholar
• Ross AC, Taylor CL, Yaktine AL, Del Valle HB. Dietary reference intakes for calcium and vitamin D. Washington (DC): National Academies Press (US); 2011.
   Google Scholar
• Holick MF, Biancuzzo RM, Chen TC, Klein EK, Young A, Bibuld D, Reitz R, Salameh W, Ameri A, Tannenbaum AD, et al. Vitamin D2 is as effective as vitamin D3 in maintaining circulating concentrations of 25-hydroxyvitamin D. J Clin Endocrinol Metab. 2008;93(3):677–81. doi:10.1210/jc.2007-2308.
   PubMed Web of Science ®Google Scholar
• Martineau AR, Thummel KE, Wang Z, Jolliffe DA, Boucher BJ, Griffin SJ, Forouhi NG, Hitman GA. Differential effects of oral boluses of vitamin D2 vs vitamin D3 on vitamin D metabolism: a randomized controlled trial. J Clin Endocrinol Metab. 2019;104(12):5831–9. doi:10.1210/jc.2019-00207.
   PubMed Web of Science ®Google Scholar
• Heaney RP, Recker RR, Grote J, Horst RL, Armas LAG. Vitamin D(3) is more potent than vitamin D(2) in humans. J Clin Endocrinol Metab. 2011;96(3):E447–E452. doi:10.1210/jc.2010-2230.
   PubMed Web of Science ®Google Scholar
• Cesareo R, Attanasio R, Caputo M, Castello R, Chiodini I, Falchetti A, Guglielmi R, Papini E, Santonati A, Scillitani A, et al. Italian association of clinical endocrinologists (AME) and Italian chapter of the American Association of Clinical Endocrinologists (AACE) position statement: clinical management of vitamin D deficiency in adults. Nutrients 2018;10(5):546. doi:10.3390/nu10050546.
   PubMed Web of Science ®Google Scholar
• Carlberg C, Velleuer E. Vitamin D and the risk for cancer: a molecular analysis. Biochem Pharmacol. 2022;196:114735. doi:10.1016/j.bcp.2021.114735.
   PubMed Web of Science ®Google Scholar
• Negri M, Gentile A, de Angelis C, Montò T, Patalano R, Colao A, Pivonello R, Pivonello C. Vitamin D-induced molecular mechanisms to potentiate cancer therapy and to reverse drug-resistance in cancer cells. Nutrient. 2020;12(6):1798. doi:10.3390/nu12061798.
   PubMed Web of Science ®Google Scholar
• Yuan C, Sato K, Hollis BW, Zhang S, Niedzwiecki D, Ou F-S, Chang I-W, O’Neil BH, Innocenti F, Lenz H-J, et al. Plasma 25-hydroxyvitamin D Levels and survival in patients with advanced or metastatic colorectal cancer: findings from CALGB/SWOG 80405 (alliance). Clin Cancer Res. 2019;25(24):7497–505. doi:10.1158/1078-0432.CCR-19-0877.
   PubMed Web of Science ®Google Scholar
• Sawada N, Inoue M, Iwasaki M, Yamaji T, Shimazu T, Sasazuki S, Tsugane S. Plasma 25-hydroxy vitamin D and subsequent prostate cancer risk in a nested case-control study in Japan: the JPHC study. Eur J Clin Nutr. 2017;71(1):132–6. doi:10.1038/ejcn.2016.184.
   PubMed Web of Science ®Google Scholar
• Estébanez N, Gómez-Acebo I, Palazuelos C, Llorca J, Dierssen-Sotos T. Vitamin D exposure and risk of breast cancer: a meta-analysis. Sci Rep. 2018;8(1):9039. doi:10.1038/s41598-018-27297-1.
   PubMedGoogle Scholar
• Yao S, Kwan ML, Ergas IJ, Roh JM, Cheng T-YD, Hong C-C, McCann SE, Tang L, Davis W, Liu S, et al. Association of serum level of vitamin D at diagnosis with breast cancer survival: a case-cohort analysis in the pathways study. JAMA Oncol. 2017;3(3):351–7. doi:10.1001/jamaoncol.2016.4188.
   PubMed Web of Science ®Google Scholar
• Skaaby T, Husemoen LLN, Thuesen BH, Pisinger C, Jørgensen T, Roswall N, Larsen SC, Linneberg A. Prospective population-based study of the association between serum 25-hydroxyvitamin-D Levels and the incidence of specific types of cancer. Cancer Epidemiol Biomarkers Prev. 2014;23(7):1220–9. doi:10.1158/1055-9965.EPI-14-0007.
   PubMed Web of Science ®Google Scholar
• Bochen F, Balensiefer B, Körner S, Bittenbring JT, Neumann F, Koch A, Bumm K, Marx A, Wemmert S, Papaspyrou G, et al. Vitamin D deficiency in head and neck cancer patients: prevalence, prognostic value and impact on immune function. Oncoimmunology. 2018;7(9):e1476817. doi:10.1080/2162402X.2018.1476817.
   PubMed Web of Science ®Google Scholar
• Zhang Y, Fang F, Tang J, Jia L, Feng Y, Xu P, Faramand A. Association between vitamin D supplementation and mortality: systematic review and meta-analysis. BMJ. 2019;366:l4673. doi:10.1136/bmj.l4673.
   PubMedGoogle Scholar
• Keum N, Lee DH, Greenwood DC, Manson JE, Giovannucci E. Vitamin D supplementation and total cancer incidence and mortality: a meta-analysis of randomized controlled trials. Ann Oncol. 2019;30(5):733–43. doi:10.1093/annonc/mdz059.
   PubMed Web of Science ®Google Scholar
• Manson JE, Cook NR, Lee I-M, Christen W, Bassuk SS, Mora S, Gibson H, Gordon D, Copeland T, D’Agostino D, VITAL Research Group, et al. Vitamin D supplements and prevention of cancer and cardiovascular disease. N Engl J Med. 2019;380(1):33–44. doi:10.1056/NEJMoa1809944.
   PubMed Web of Science ®Google Scholar
• Podgorska E, Drzal A, Matuszak Z, Swakon J, Slominski A, Elas M, Urbanska K. Calcitriol and calcidiol can sensitize melanoma cells to low − LET proton beam irradiation. Int J Mol Sci. 2018;19(8):2236. doi:10.3390/ijms19082236.
   PubMed Web of Science ®Google Scholar
• Zeichner SB, Koru-Sengul T, Shah N, Liu Q, Markward NJ, Montero AJ, Glück S, Silva O, Ahn ER. Improved clinical outcomes associated with vitamin D supplementation during adjuvant chemotherapy in patients with HER2+ nonmetastatic breast cancer. Clin Breast Cancer. 2015;15(1):e1–e11. doi:10.1016/j.clbc.2014.08.001.
   PubMedGoogle Scholar
• Morita M, Okuyama M, Akutsu T, Ohdaira H, Suzuki Y, Urashima M. Vitamin D supplementation regulates postoperative serum levels of PD-L1 in patients with digestive tract cancer and improves survivals in the highest quintile of PD-L1: A post hoc analysis of the Amaterasu randomized controlled trial. Nutrients. 2021;13(6):1987. doi:10.3390/nu13061987.
   PubMed Web of Science ®Google Scholar
• Kondrup J, Johansen N, Plum LM, Bak L, Larsen IH, Martinsen A, Andersen JR, Baernthsen H, Bunch E, Lauesen N, et al. Incidence of nutritional risk and causes of inadequate nutritional care in hospitals. Clin Nutr. 2002;21(6):461–8. doi:10.1054/clnu.2002.0585.
   PubMed Web of Science ®Google Scholar
• Kondrup J, Allison SP, Elia M, Vellas B, Plauth M. ESPEN guidelines for nutrition screening 2002. Clin Nutr. 2003;22(4):415–21. doi:10.1016/s0261-5614(03)00098-0.
   PubMed Web of Science ®Google Scholar
• van Schoor N, Lips P. Global overview of vitamin D status. Endocrinol Metab Clin North Am. 2017;46(4):845–70. doi:10.1016/j.ecl.2017.07.002.
   PubMed Web of Science ®Google Scholar
• Yu S, Fang H, Han J, Cheng X, Xia L, Li S, Liu M, Tao Z, Wang L, Hou L, et al. The high prevalence of hypovitaminosis D in China: a multicenter vitamin D status survey. Medicine (Baltimore). 2015;94(8):e585. doi:10.1097/MD.0000000000000585.
   PubMed Web of Science ®Google Scholar
• Chandler PD, Buring JE, Manson JE, Giovannucci EL, Moorthy MV, Zhang S, Lee IM, Lin JH. Circulating vitamin D Levels and risk of colorectal cancer in women. Cancer Prev Res (Phila). 2015;8(8):675–82. doi:10.1158/1940-6207.CAPR-14-0470.
   PubMed Web of Science ®Google Scholar
• Ortiz-Sánchez C, Encarnación-Medina J, Vergne R, Padilla L, Matta J. Circulating vitamin D levels and DNA repair capacity in four molecular subtypes of women with breast cancer. Int J Mol Sci. 2020;21(18):6880. doi:10.3390/ijms21186880.
   PubMed Web of Science ®Google Scholar
• Al-Ghafari AB, Balamash KS, Al Doghaither HA. Relationship between serum vitamin D and calcium levels and vitamin D receptor gene polymorphisms in colorectal cancer. Biomed Res Int. 2019;2019:8571541. doi:10.1155/2019/8571541.
   PubMed Web of Science ®Google Scholar
• Lucas RM, Ponsonby A-L, Dear K, Valery PC, Taylor B, van der Mei I, McMichael AJ, Pender MP, Chapman C, Coulthard A, et al. Vitamin D status: multifactorial contribution of environment, genes and other factors in healthy Australian adults across a latitude gradient. J Steroid Biochem Mol Biol. 2013;136:300–8. doi:10.1016/j.jsbmb.2013.01.011.
   PubMed Web of Science ®Google Scholar
• Yan X, Zhang N, Cheng S, Wang Z, Qin Y. Gender differences in vitamin D status in China. Med Sci Monit. 2019;25:7094–9. doi:10.12659/MSM.916326.
   PubMed Web of Science ®Google Scholar
• Yao Y, Fu S, Li N, Hu F, Zhang H, Zhu Q, Luan F, Zhang F, Zhao Y, He Y, et al. Sex, residence and fish intake predict vitamin D status in Chinese centenarians. J Nutr Health Aging. 2019;23(2):165–71. doi:10.1007/s12603-018-1126-1.
   PubMed Web of Science ®Google Scholar
• Yoshimura N, Muraki S, Oka H, Morita M, Yamada H, Tanaka S, Kawaguchi H, Nakamura K, Akune T. Profiles of vitamin D insufficiency and deficiency in Japanese men and women: Association with biological, environmental, and nutritional factors and coexisting disorders: The ROAD study. Osteoporos Int. 2013;24(11):2775–87. doi:10.1007/s00198-013-2372-z.
   PubMed Web of Science ®Google Scholar
• Yu S, Zhang R, Zhou W, Cheng X, Cheng Q, Xia L, Xie S, Yin Y, Sun D, Su W, et al. Is it necessary for all samples to quantify 25OHD2 and 25OHD3 using LC-MS/MS in clinical practice? Clin Chem Lab Med. 2018;56(2):273–7. doi:10.1515/cclm-2017-0520.
   PubMed Web of Science ®Google Scholar
• Suzuki T, Kwon J, Kim H, Shimada H, Yoshida Y, Iwasa H, Yoshida H. Low serum 25-hydroxyvitamin D levels associated with falls among Japanese community-dwelling elderly. J Bone Miner Res. 2008;23(8):1309–17. doi:10.1359/jbmr.080328.
   PubMed Web of Science ®Google Scholar
• Janssen HCJP, Emmelot-Vonk MH, Verhaar HJJ, van der Schouw YT. Determinants of vitamin D status in healthy men and women aged 40-80 years. Maturitas. 2013;74(1):79–83. doi:10.1016/j.maturitas.2012.10.008.
   PubMed Web of Science ®Google Scholar
• Chin K-Y, Ima-Nirwana S, Ngah W. Vitamin D is significantly associated with total testosterone and sex hormone-binding globulin in Malaysian men. Aging Male. 2015;18(3):175–9. doi:10.3109/13685538.2015.1034686.
   PubMed Web of Science ®Google Scholar
• Tak YJ, Lee JG, Kim YJ, Park NC, Kim SS, Lee S, Cho BM, Kong EH, Jung DW, Yi YH, et al. Serum 25-hydroxyvitamin D Levels and testosterone deficiency in middle-aged Korean men: a cross-sectional study. Asian J Androl. 2015;17(2):324–8. doi:10.4103/1008-682X.142137.
   PubMed Web of Science ®Google Scholar
• Vimaleswaran KS, Berry DJ, Lu C, Tikkanen E, Pilz S, Hiraki LT, Cooper JD, Dastani Z, Li R, Houston DK, Genetic Investigation of Anthropometric Traits-GIANT Consortium, et al. Causal relationship between obesity and vitamin D status: Bi-directional Mendelian randomization analysis of multiple cohorts. PLoS Med. 2013;10(2):e1001383. doi:10.1371/journal.pmed.1001383.
   PubMed Web of Science ®Google Scholar
• Vanlint S. Vitamin D and obesity. Nutrients. 2013;5(3):949–56. doi:10.3390/nu5030949.
   PubMed Web of Science ®Google Scholar
• Rosenstreich SJ, Rich C, Volwiler W. Deposition in and release of vitamin D3 from body fat: Evidence for a storage site in the rat. J Clin Invest. 1971;50(3):679–87. doi:10.1172/JCI106538.
   PubMed Web of Science ®Google Scholar
• Greenlee H, White E, Patterson RE, Kristal AR, Vitamins and Lifestyle (VITAL) Study Cohort. Supplement use among cancer survivors in the vitamins and lifestyle (VITAL) study cohort. J Altern Complement Med. 2004;10(4):660–6. doi:10.1089/acm.2004.10.660.
   PubMed Web of Science ®Google Scholar
• Zhao J, Wang H, Zhang Z, Zhou X, Yao J, Zhang R, Liao L, Dong J. Vitamin D deficiency as a risk factor for thyroid cancer: a meta-analysis of case-control studies. Nutrition. 2019;57:5–11. doi:10.1016/j.nut.2018.04.015.
   PubMed Web of Science ®Google Scholar
• Urashima M, Ohdaira H, Akutsu T, Okada S, Yoshida M, Kitajima M, Suzuki Y. Effect of vitamin D supplementation on relapse-free survival among patients with digestive tract cancers: the Amaterasu randomized clinical trial. JAMA. 2019;321(14):1361–9. doi:10.1001/jama.2019.2210.
   PubMed Web of Science ®Google Scholar