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Articles

Demodex folliculorum and Demodex brevis (Acari: Demodecidae) and their association with facial and non-facial pathologies

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Pages 396-403 | Received 28 Dec 2020, Accepted 13 Apr 2021, Published online: 12 May 2021

References

  • Akilov OE, Butov YS, Mumcuoglu KY. 2005. A clinico-pathological approach to the classification of human demodicosis. Journal der Deutschen Dermatologischen Gesellschaft. 3:607–614.
  • Akilov OE, Mumcuoglu KY. 2004. Immune response in demodicosis. Journal of the European Academy of Dermatology and Venereology: JEADV. 18:440–444.
  • Ando T, Homma R, Ino Y, Ito G, Miyahara A, Yanagihara T, Kimura H, Ikeda S, Yamakawa H, Iwaki M, et al. 1993. Trypsin-like protease of mites: purification and characterization of trypsin-like protease from mite faecal extract Dermatophagoides farinae. Relationship between trypsin-like protease and Der f III. Clinical Experimental Allergy. 23:777–784. doi:10.1111/j.1365-2222.1993.tb00366.x
  • Arici MK, Sűmer Z, Toker MI, Erdoğan H, Topalkara A, Akbulut M. 2005. The prevalence of Demodex folliculorum in blepharitis patients and the normal population. Ophthalmic Epidemiology. 12:287–290.
  • Aşkin U, Seçkin D. 2010. Comparison of the two techniques for measurement of the density of Demodex folliculorum: standardized skin surface biopsy and direct microscopic examination. The British Journal of Dermatology. 162:1124–1126.
  • Aydingöz IE, Dervent B, Güney O. 2000. Demodex folliculorum in pregnancy. International Journal of Dermatology. 39:743–745.
  • Aylesworth R, Vance JC. 1982. Demodex folliculorum and Demodex brevis in cutaneous biopsies. Journal of the American Academy of Dermatology. 7:583–589.
  • Ayres S Jr. 1961. Demodectic eruptions (demodicidosis) in the human. 30 years’ experience with 2 commonly unrecognized entities: pityriasis folliculorum (Demodex) and acne rosacea (Demodex type). Archives of Dermatology. 83:816–827.
  • Bagdad JD, Nielson KL, Bulger RJ. 1972. Reversible abnormalities in phagocytic function in poorly controlled diabetic patients. The American Journal of the Medical Sciences. 263:451–456.
  • Baima B, Sticherling M. 2002. Demodicidosis revisited. Acta dermato-venereologica. 82:3–6.
  • Barrio J, Lecona M, Hernanz JM, Sánchez M, Gurbindo MD, Lázaro P, Barrio JL. 1996. Rosacea like demodicosis in an HIV positive child. Dermatology. 192:143–145.
  • Benk Silfeler D, Keskin Kurt R, Kaya OA, Yengil E, Hamamci B, Okyay AG, Beyazit A. 2015. Demodex folliculorum in polycystic ovary syndrome patients. European Review for Medical and Pharmacological Sciences. 19:1141–1145.
  • Bielenin I, Białczyk E. 1993. Infestations of demodicids (Demodicidae, Acarina) and their economic, sanitary and epidemiological significance (in Polish with English abstract). Przeglad Zoologiczny. 37:187–197.
  • Bonnar E, Eustace P, Powell FC. 1993. The Demodex mite population in rosacea. Journal of the American Academy of Dermatology. 28:443–448.
  • Brattig NW. 2004. Pathogenesis and host responses in human onchocerciasis: impact of Onchocerca filariae and Wolbachia endobacteria. Microbes And Infection/Institut Pasteur. 6:113–128.
  • Cardwell LA, Alinia H, Tuchayi SM, Feldman SR. 2016. New developments in the treatment of rosacea – role of once daily ivermectin cream. Clinical, Cosmetic and Investigational Dermatology. 9:71–77.
  • Casas C, Paul C, Lahfa M, Livideanu B, Lejeune O, Alvarez-Georges S, Saint-Martory C, Degouy A, Mengeaud V, Ginisty H, et al. 2012. Quantification of Demodex folliculorum by PCR in rosacea and its relationship to skin innate immune activation. Experimental Dermatology. 21:906–910. doi:10.1111/exd.12030
  • Chen W, Plewig G. 2014. Human demodicosis: revisit and a proposed classification. The British Journal of Dermatology. 170:1219–1225.
  • Clyti E, Sayavong K, Chanthavisouk K. 2005. Demodecidosis in a patient infected by HIV: successful treatment with ivermectin. Annales de dermatologie et de venereologie. 132:459–461.
  • Craig JP, Tomlinson A. 1997. Importance of the lipid layer in human tear film stability and evaporation. Optometry and Vision Science: Official Publication of the American Academy of Optometry. 74:8–13.
  • Czepita D, Kuzna-Grygiel W, Czepita M, Grobelny A. 2007. Demodex folliculorum and Demodex brevis as a cause of chronic marginal blepharitis. Annales Academiae Medicae Stetinensis. 53:63e7.
  • Czepita D, Kuźna-Grygiel W, Kosik-Bogacka D. 2005a. Demodex as an etiological factor in chronic blepharitis (in Polish with English abstract). Klin Oczna. 107:722–724.
  • Czepita D, Kuźna-Grygiel W, Kosik-Bogacka D. 2005b. Investigations on the occurrence as well as the role of Demodex folliculorum and Demodex brevis in the pathogenesis of blepharitis (in Polish with English abstract). Klin Oczna. 107:80–82.
  • Damian D, Rogers M. 2003. Demodex infestation in a child with leukaemia: treatment with ivermectin and permethrin. International Journal of Dermatology. 42:724–726.
  • De Rojas M, Riazzo C, Callejon R, Guevara D, Cutillas C. 2012. Molecular study on three morphotypes of Demodex mites (Acarina: Demodicidae) from dogs. Parasitology Research. 111:2165–2172.
  • Desch C, Nutting WB. 1972. Demodex folliculorum (Simon) and D. brevis Akbulatova of man: redescription and reevaluation. The Journal of Parasitology. 58:169–177.
  • Diaz-Perez JL. 1994. Demodex mites in rosacea. Journal of the American Academy of Dermatology. 30:812–813.
  • Dolenc-Voljc M, Pohar M, Lunder T. 2005. Density of Demodex folliculorum in perioral dermatitis. Acta dermato-venereologica. 85:211–215.
  • El-Bassiouni SO, Ahmed JA, Younis AI, Ismail MA, Saadawi AN, Bassiouni SO. 2005. A study on Demodex folliculorum mite density and immune response in patients with facial dermatoses. Journal of the Egyptian Society of Parasitology. 35:899–910.
  • Elston CA, Elston DM. 2014. Demodex mites. Clinics in Dermatology. 32:739–743.
  • Enginyurt O, Karaman U, Cetin F, Ozer A. 2015. The prevalence of Demodex species and its relationship with the metabolic syndrome in women of Malatya Province, Turkey. Jundishapur Journal of Microbiology. 8:e24322.
  • Eser A, Erpolat S, Kaygusuz I, Balci H, Kosus A. 2017. Investigation of Demodex folliculorum frequency in patients with polycystic ovary syndrome. Anais Brasileiros De Dermatologia. 92:807–810.
  • Firat PY, Gecit I, Depecik F, Karadan M, Karci E, Karaman U, Calik S. 2010. Demodex spp. positivity among laboratory staff, kitchen staff, cleaning workers and nurses working in a state hospital. Turkiye Parazitol Dergisi. 34:164–167.
  • Fischer K, Walton S. 2014. Parasitic mites of medical and veterinary importance–is there a common research agenda? International Journal for Parasitology. 44:955–967.
  • Flores I, Mora C, Rivera E, Donnelly R, Montealegre F. 2003. Cloning and molecular characterization of a cDNA from Blomia tropicalis homologous to dust mite group 3 allergens (trypsin-like proteases). International Archives of Allergy and Immunology. 130:12–16.
  • Forton F, Germaux MA, Brasseur T, De Liever A, Laporte M, Mathys C, Sass U, Stene -J-J, Thibaut S, Tytgat M, et al. 2005. Demodicosis and rosacea: epidemiology and significance in daily dermatologic practice. Journal of the American Academy of Dermatology. 52:74–87. doi:10.1016/j.jaad.2004.05.034
  • Forton F, Seys B. 1993. Density of Demodex folliculorum in rosacea: a case-control study using standardized skin surface biopsy. The British Journal of Dermatology. 128:650–659.
  • Forton F, Seys B, Marchal JL, Song AM. 1998. Demodex folliculorum and topical treatment: acaricidal action evaluated by standardized skin surface biopsy. The British Journal of Dermatology. 138:461–466.
  • Fulk G, Clifford C. 1990. A case report of demodicosis. Journal of the American Optometric Association. 61:637–639.
  • Fulk GW, Murphy B, Robins MD. 1996. Pilocarpine gel for the treatment of demodicosis–a case series. Optometry and Vision Science: Official Publication of the American Academy of Optometry. 73:742–745.
  • Gao YY, Xu DL, Huang L, Wang R, Tseng SC. 2012. Treatment of ocular itching associated with ocular demodicosis by 5% tea tree oil ointment. Cornea. 31:14e7.
  • Geerling G, Tauber J, Baudouin C, Goto E, Matsumoto Y, O’Brien T, Rolando M, Tsubota K, Nichols KK. 2011. The international workshop on meibomian gland dysfunction: report of the sub-committee on management and treatment of meibomian gland dysfunction. Investigative Ophthalmology & Visual Science. 52:2050–2064.
  • Gerber PA, Kukova G, Buhren BA, Homey B. 2011. Density of Demodex folliculorum in patients receiving epidermal growth factor receptor inhibitors. Dermatology. 222:144–147.
  • Gerkowicz M, Baltaziak L, Puacz E. 2005. Chronic blepharitis caused by mite Demodex folliculorum (in Polish with English abstract). Klin Oczna. 107:376–378.
  • Grobelny A, Czepita D, Kuźna-Grygiel W. 2006. Prevalence of eyelids demodicidosis in the home for the elderly in Borne Sulinowo (in Polish). Proceedings of the 8th Symposium of the Ergophthalmological Section as well as 11th Symposium of the Section on Prevention of Blindness and Low Vision Rehabilitation of the Polish Ophthalmological Society; Lublin; p. 97.
  • Grosshans EM, Kremer M, Maleville J. 1974. Demodex folliculorum and the histogenesis of granulomatous rosacea. Hautarzt. 25:166–177.
  • Holzchuh FG, Hida RY, Moscovici BK, Villa Albers MB, Santo RM, Kara-José N, Holzchuh R. 2011. Clinical treatment of ocular Demodex folliculorum by systemic ivermectin. American Journal of Ophthalmology. 151:1030–1034.e1.
  • Housman E, Reynolds RV. 2014. Polycystic ovary syndrome: a review for dermatologists: Part I. Diagnosis and manifestations. Journal of the American Academy of Dermatology. 71:847.e1–847.e10.
  • Hsu CK, Hsu MM, Lee JY. 2009. Demodicosis: a clinicopathological study. Journal of the American Academy of Dermatology. 60:453–462.
  • Hu Q, Wang Y. 2001. Investigation on the prevalence of human Demodex among 2248 medical students in inner Mongolia. Zhongguo Ji Sheng Chong Xue Yu Ji Shen Chon Bing Za Zhi. 19:239–240.
  • Humiczewska M, Kuźna W, Hermach U. 1994. Frequency of occurrence of symptomatic and asymptomatic eyelids demodecosis among the inhabitants of Szczecin (in Polish with English abstract). Wiad Parazytol. 40:69–71.
  • Intahphuak S, Khonsung P, Panthong A. 2010. Anti-inflammatory, analgesic, and anti-pyretic activities of virgin coconut oil. Le Pharmacien Biologiste. 48:151–157.
  • Ionescu MA, Joly F, Bombard E, Robert G, Lefeuvre L, Bohbot M. 2015. TLR-2, cathelicidin-LL37 and kallikrein-5 targeting in rosacea: in tubo, ex vivo and in vivo studies. Journal of the American Academy of Dermatology. 72:65.
  • Jimenez-Acosta F, Planas L, Penneys N. 1989. Demodex mites contain immunoreactive lipase. Archives of Dermatology. 125:1436–1437.
  • Jing X, Shuling G, Ying L. 2005. Environmental scanning electron microscopy observation of the ultrastructure of Demodex. Microscopy Research and Technique. 68:284–289.
  • Jones L, Downie LE, Korb D, Benitez-del-castillo JM, Dana R, Deng SX, Craig JP. 2017. TFOS DEWS II management and therapy report. The Ocular Surface. 15:575–628.
  • Juliandri J, Wang X, Liu Z, Zhang J, Xu Y, Yuan C. 2019. Global rosacea treatment guidelines and expert consensus points: the differences. Journal of Cosmetic Dermatology. 18:960.
  • Junk AK, Lukacs A, Kampik A. 1998. Topical administration of metronidazole gel as an effective therapy alternative in chronic Demodex blepharitis—a case report. Klin Monatsbl Augenheilkd. 213:48–50.
  • Kamoun B, Fourati M, Feki J, Mlik M, Karray F, Trigui A, Ellouze S, Hammami B, Chaabouni M, Ayadi A. 1999. Blépharite à Démodex: mythe ou réalité? [Blepharitis due to Demodex: myth or reality?]. Journal Francais D’ophtalmologie. 22:525–527.
  • Karabay EA, Çerman AA. 2020. Infestação por Demodex folliculorum em dermatoses faciais comuns: acne vulgar, rosácea, dermatite seborreica. Anais Brasileiros De Dermatologia. 95:187–193.
  • Karincaoglu Y, Bayram N, Aycan O, Esrefoglu M. 2004. The clinical importance of Demodex folliculorum presenting with nonspecific facial signs and symptoms. The Journal of Dermatology. 31:618–626.
  • Karincaoglu Y, Seyhan ME, Bayram N, Aycan O, Taskapan H. 2005. Incidence of Demodex folliculorum in patients with end stage chronic renal failure. Renal Failure. 27:495–499.
  • Kemal M, Sümer Z, Toker MI, Erdoğan H, Topalkara A, Akbulut M. 2005. The prevalence of Demodex folliculorum in blepharitis patients and the normal population. Ophthalmic Epidemiology. 12:287–290.
  • Kenyon F, Knox D. 2002. The proteinases of Psoroptes ovis, the sheep scab mite: their diversity and substrate specificity. Veterinary Parasitology. 105:317–325.
  • Kim MS, Kim BS, Koh WS, Lee SS, Seo SL, Chun DK, Park SM. 2001. Rosacea: clinical study of 67 cases. Annals of Dermatology. 13:39–43.
  • Kiuchi K. 2018. Better detection of Demodex mites by Löffler’s alkaline methylene blue staining in patients with blepharitis. Clinical Ophthalmology. 12:727–731.
  • Koo H, Kim TH, Kim KW, Wee SW, Chun YS, Kim JC. 2012. Ocular surface discomfort and Demodex: effect of tea tree oil eyelid scrub in Demodex blepharitis. Journal of Korean Medical Science. 27:1574e9.
  • Kubanov A, Gallyamova Y, Kravchenko A. 2019. Clinical picture, diagnosis and treatment of rosacea, complicated by Demodex mites. Dermatology Reports. 11:7675.
  • Kuzna-Grygiel W, Kosik-Bogacka D, Czepita D. 2003. Demodex folliculorum and Demodex brevis in the etiology of blepharitis (in Polish). Proceedings of the XVI Meeting of the Polish Society of Epidemiologists and Infectious Diseases Doctors; Białystok; p. 28–32.
  • Kwiatkowska-Kawecka Z. 1982. A case of Demodex blepharitis from Poland (in Polish with English abstract). Wiadomosci Parazytologiczne. 28:123–124.
  • Lacey N, Delaney S, Kavanagh K, Powell FC. 2007. Mite-related bacterial antigens stimulate inflammatory cells in rosacea. The British Journal of Dermatology. 157:474–481.
  • Lacey N, Raghallaigh SN, Powell FC. 2011. Demodex mites–commensals, parasites or mutualistic organisms. Dermatology. 222:128–130.
  • Lacey N, Russell-Hallinan A, Powell FC. 2016. Study of Demodex mites: challenges and solutions. Journal of the European Academy of Dermatology and Venereology: JEADV. 30:764–775.
  • Li F, Wang YP. 1986. Using gluey cellophane tape for lab diagnosis of demodicosis. Journal of Norman Bethune University of Medical Sciences. 12:298–300. (in Chinese).
  • Litwin D, Chen W, Dzika E, Korycińska J. 2017. Human permanent ectoparasites; recent advances on biology and clinical significance of Demodex mites: narrative review article. Iranian Journal of Parasitology. 12:12–21.
  • Liu J, Sheha H, Tseng SC. 2010. Pathogenic role of Demodex mites in blepharitis. Current Opinion in Allergy and Clinical Immunology. 10:505.
  • Madeira NG, Sogayar MI. 1993. The prevalence of Demodex folliculorum and Demodex brevis in a population sample from Botucatu, São Paulo, Brazil. Revista Da Sociedade Brasileira De Medicina Tropical. 26:221–224.
  • Moran EM, Foley R, Powell FC. 2017. Demodex and rosacea revisited. Clinics in Dermatology. 35:195–200.
  • Moriguchi P, Sannomiya P, Lara PF, Oliveira-Filho RM, Greco KV, Sudo-Hayashi LS. 2005. Lymphatic system changes in diabetes mellitus: role of insulin and hyperglycemia. Diabetes/metabolism Research and Reviews. 21:150–157.
  • Mowat A, Baum J. 1971. Chemotaxis of polymorphonuclear leukocytes from patients with diabetes mellitus. The New England Journal of Medicine. 284:621–627.
  • Mullen G, Oconnor BM. 2002. MITES (Acari). In: Medical and veterinary entomology. Amsterdam: Academic Press; p. 449–516.
  • Murillo N, Aubert J, Raoult D. 2014. Microbiota of Demodex mites from rosacea patients and controls. Microbial Pathogenesis. 71–72:37–40.
  • Namazi MR. 2007. A possible role for human follicle mites in skin’s defense against bacteria. Indian Journal of Dermatology, Venereology and Leprology. 73:270.
  • Nara T, Katoh N, Inoue K, Yamada M, Arizono N, Kishimoto S. 2009. Eosinophilic folliculitis with a Demodex folliculorum infestation successfully treated with ivermectin in a man infected with human immunodeficiency virus. Clinical and Experimental Dermatology. 34:e981–3.
  • Norn MS. 1970. Demodex folliculorum. Incidence and possible pathogenic role in the human eyelid. Acta ophthalmologica. 108:1–85.
  • Norn MS. 1982. Incidence of Demodex folliculorum on skin of lids and nose. Acta ophthalmologica. 60:575–583.
  • Nutting WB. 1976. Hair follicle mites (Acari: Demodicidae) of man. International Journal of Dermatology. 15:79–98.
  • O’Reilly N, Bergin D, Reeves EP, McElvaney NG, Kavanagh K. 2012. Demodex-associated bacterial proteins induce neutrophil activation. The British Journal of Dermatology. 166:753–760.
  • Okyay P, Ertabaklar H, Savk E, Ertug S. 2006. Prevalence of Demodex folliculorum in young adults: relation with sociodemographic/hygienic factors and acne vulgaris. The Journal of the European Academy of Dermatology and Venereology. 20:474–476.
  • Özdemir MH, Aksoy U, Akisu C, Sönmez E, Çakmak MA. 2003. Investigating Demodex in forensic autopsy cases. Forensic Science International. 135:226–231.
  • Powell F, Foley R, Gatault S. 2020. Demodex folliculorum: role of pathogenesis or association. In: Cary JH, Maibach HI, editors. Rosacea. Updates in clinical dermatology. Cham: Springer; p. 129–139.
  • Powell FC. 2005. Clinical practice. Rosacea New England Journal of Medicine. 352:793–803.
  • Prokopowicz D. 1995. Demodicidosis (in polish). In: Prokopowicz D, editor. Choroby przenoszone przez kleszcze. Warszawa: Wydaw. Fundacji Büchnera; p. 207–212.
  • Purcell SM, Hayes TJ, Dixon SL. 1986. Pustular folliculitis associated with Demodex folliculorum. Journal of the American Academy of Dermatology. 15:1159–1162.
  • Raedler LA. 2015. Soolantra (Ivermectin) 1% cream: a novel, antibiotic-free agent approved for the treatment of patients with Rosacea. American Health & Drug Benefits. 8:122–125.
  • Rather PA, Hassan I. 2014. Human Demodex mite: the versatile mite of dermatological importance. Indian Journal of Dermatology. 59:60–66.
  • Roihu T, Kariniemi AL. 1998. Demodex mites in acne rosacea. Journal of Cutaneous Pathology. 25:550–552.
  • Román-Curto C, Meseguer-Yebra C, Cañueto J, Fraile‐Alonso C, Santos‐Briz A, Vázquez L, Fernández‐López E. 2012. Demodicidosis simulating acute graft-versus-host disease after allogeneic stem cell transplantation in one patient with acute lymphoblastic leucemia. Transplant Infectious Disease: An Official Journal of the Transplantation Society. 14:387–390.
  • Rosławska A, Humiczewska-Rajska M, Baranowska-George T. 1984. Demodex folliculorum in the aetiology of chronic marginal blepharitis (in Polish with English abstract). Klin Oczna. 86:157–158.
  • Rufli T, Buchner SA. 1984. T-cell subsets in acne rosacea lesions and the possible role of Demodex folliculorum. Dermatologica. 169:1–5.
  • Rufli T, Mumcuoglu Y. 1981. The hair follicle mites Demodex folliculorum and Demodex brevis: biology and medical importance. A review. Dermatologica. 162:1–11.
  • Sanchez-Viera M, Hernanz JM, Sampelayo T, Gurbindo MD, Lecona M. 1992. Granulomatous rosacea in a child infected with the human immunodeficiency virus. Journal of the American Academy of Dermatology. 27:1010–1011. doi:10.1016/S0190-9622(08)80268-X
  • Sannomiya P, Oliveira MA, Fortes ZB. 1997. Aminoguanidine and the prevention of leukocyte dysfunction in diabetes mellitus: a direct vital microscopic study. British Journal of Pharmacology. 122:894–898.
  • Schaller M, Gonser L, Belge K, Braunsdorf C, Nordin R, Scheu A, Borelli C. 2017. Dual anti-inflammatory and anti-parasitic action of topical ivermectin 1% in papulopustular rosacea. Journal of the European Academy of Dermatology and Venereology: JEADV. 31:1907–1911. doi:10.1111/jdv.14437
  • Sengbusch HG, Hauswirth JW. 1986. Prevalence of hair follicle mites, Demodex folliculorum and D. brevis (Acari: Demodicidae), in a selected human population in western New York, USA. Journal of Medical Entomology. 23:384–388.
  • Seyhan ME, Karincaoğlu Y, Bayram N, Aycan O, Kuku I. 2004. Density of Demodex folliculorum in haematological malignancies. The Journal of International Medical Research. 32:411–415.
  • Spickett SG. 1961. Studies on Demodex folliculorum Simon (1842). I. Life history. Parasitology. 51:181–192.
  • Szkaradkiewicz A, Chudzicka-Strugała I, Karpiński TM, Goślińska-Pawłowska O, Tułecka T, Chudzicki W, Szkaradkiewicz AK, Zaba R. 2012. Bacillus oleronius and Demodex mite infestation in patients with chronic blepharitis. Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases. 18:1020–1025.
  • Thoemmes MS, Fergus DJ, Urban J, Trautwein M, Dunn RR. 2014. Ubiquity and diversity of human-associated Demodex mites. PLoS One. 9:e106265.
  • Turgut Erdemir A, Gurel MS, Koku Aksu AE, Falay T, Inan Yuksel E, Sarikaya E. 2017. Demodex mites in acne rosacea: reflectance confocal microscopic study. The Australasian Journal of Dermatology. 58:e26–30.
  • Verallo-Rowell VM, Dillague KM, Syah-Tjundawan BS. 2008. Novel antibacterial and emollient effects of coconut and virgin olive oils in adult atopic dermatitis. Dermatitis. 19:308–315.
  • Wegner Z. 1999. Demodex folliculorum (Simon, 1842) (in polish). In: Kadłubowski R, Kurantowska A, editors. Zarys parazytologii lekarskiej. Warszawa: Wydaw. Lek. PZWL; p. 304–305.
  • Wolf R, Ophir J, Avigad J, Lengy J, Krakowski A. 1988. The hair follicle mites (Demodex spp.): could they be vectors of pathogenic microorganisms? Acta Dermato-venereologica. 68:535–537.
  • Wong K, Flanagan J, Jalbert I, Tan J. 2019. The effect of blephadex™ eyelid wipes on Demodex mites, ocular microbiota, bacterial lipase and comfort: a pilot study. Contact Lens & Anterior Eye: The Journal of the British Contact Lens Association. 42:652–657.
  • Yagdiran Düzgün O, Aytekin S. 2007. Comparison of Demodex folliculorum density in haemodialysis patients with a control group. Journal of the European Academy of Dermatology and Venereology: JEADV. 21:480–483.
  • Yamashita LS, Cariello AJ, Geha NM, Yu MC, Hofling-Lima AL. 2011. Demodex folliculorum on the eyelash follicle of diabetic patients. Arquivos Brasileiros De Oftalmologia. 74:422–424.
  • Yazar S, Ozcan H, Cetinkaya U. 2008. Investigation of Demodex sp. using cellophane tape method among university students. Turkiye Parazitol Dergisi. 32:238–240.
  • Yucel A, Yilmaz M. 2013. Investigation of the prevalence of Demodex folliculorum and Demodex brevis in rosacea patients. Turkiye Parazitol Dergisi. 37:195–198.
  • Yun CH, Yun JH, Baek JO, Roh JY, Lee JR. 2017. Demodex mite density determinations by standardized skin surface biopsy and direct microscopic examination and their relations with clinical types and distribution patterns. Annals of Dermatology. 29:137–142.
  • Zhao Y, Yang F, Wang R, Niu D, Mu X, Yang R, Hu L. 2017. Association study of Demodex bacteria and facial dermatoses based on DGGE technique. Parasitology Research. 116:945–951. doi:10.1007/s00436-016-5370-1
  • Zhao Y-E, Guo N, Xun M, Xu J-R, Wang M, Wang D-L. 2011a. Sociodemographic characteristics and risk factor analysis of Demodex infestation (Acari: Demodicidae). Journal of Zhejiang University Science B. 12:998–1007.
  • Zhao YE, Hu L, Wu LP, Ma JX. 2012. A meta-analysis of association between acne vulgaris and Demodex infestation. Journal of Zhejiang University Science B. 13:192–202.
  • Zhao YE, Peng Y, Wang XL, Wu LP, Wang M, Yan HL, Xiao S-X. 2011b. Facial dermatosis associated with Demodex: a case-control study. Journal of Zhejiang University Science B. 12:1008–1015.
  • Zhu M, Cheng C, Yi H, Lin L, Wu K. 2018. Quantitative analysis of the bacteria in blepharitis with Demodex infestation. Frontiers in Microbiology. 9:1719.

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