Spontaneous periocular ecchymosis: a major review

References

• Lee Y, Hwang K. Skin thickness of Korean adults. Surg Radiol Anat. 2002;24(3–4):183–189. doi:10.1007/s00276-002-0034-5.
   PubMed Web of Science ®Google Scholar
• Kels BD, Grzybowski A, Grant-Kels JM. Human ocular anatomy. Clin Dermatol. 2015;33(2):140–146. doi:10.1016/j.clindermatol.2014.10.006.
   PubMed Web of Science ®Google Scholar
• Clements R, Dhar S. Raccoon eyes sign in a multi-system disease. J R Coll Physicians Edinb. 2021;51(2):162–163. doi:10.4997/JRCPE.2021.215.
   PubMed Web of Science ®Google Scholar
• Moran DE, Donoghue V. Periorbital ecchymosis (‘raccoon eyes’) as the presenting feature of neuroblastoma. Pediatr Radiol. 2010;40(10):1710. doi:10.1007/s00247-009-1467-3.
   PubMed Web of Science ®Google Scholar
• Mandal PK, Dolai TK. Raccoon eyes in immune thrombocytopenia (ITP). J Appl Hematol. 2014;5(1):32. doi:10.4103/1658-5127.131825.
   Google Scholar
• Cartoni C, Niscola P, Breccia M, Brunetti G, D’Elia GM, Giovannini M, et al. Hemorrhagic complications in patients with advanced hematological malignancies followed at home: an Italian experience. Leuk Lymphoma. 2009;50(3):387–391. doi:10.1080/10428190802714024.
   PubMed Web of Science ®Google Scholar
• Rastogi P, Naseem S, Varma N, Das R, Ahluwalia J, Sachdeva MUS, et al. Bone marrow involvement in neuroblastoma: a study of hemato-morphological features. Indian J Hematol Blood Transfus. 2015;31(1):57–60. doi:10.1007/s12288-014-0405-1.
   PubMed Web of Science ®Google Scholar
• Jandial A, Mishra K, Khadwal A, Malhotra P. Spontaneous periorbital ecchymosis: a rare presentation of acute lymphoblastic leukaemia. BMJ. 2018:bcr-2018–224228. doi:10.1136/bcr-2018-224228.
   Google Scholar
• Joseph JJ, Rajan A, Gulley JL, Ito S, Kessler CM. Acquired coagulopathy with immune checkpoint inhibitors: an underrecognized association between inflammation and coagulation. JTO Clin Res Rep. 2020;1(3):100049. doi:10.1016/j.jtocrr.2020.100049.
   PubMedGoogle Scholar
• Rajwanshi A, Srinivas R, Upasana G. Malignant small round cell tumors. J Cytol. 2009;26(1):1–10. doi:10.4103/0970-9371.54861.
   PubMed Web of Science ®Google Scholar
• Musarella MA, Chan HS, DeBoer G, Gallie BL. Ocular involvement in neuroblastoma: prognostic implications. Ophthalmology. 1984 August;91(8):936–940. doi:10.1016/s0161-6420(84)34211-7.
   PubMed Web of Science ®Google Scholar
• DuBois SG, Kalika Y, Lukens JN, Brodeur GM, Seeger RC, Atkinson JB, et al. Metastatic sites in stage IV and IVS neuroblastoma correlate with age, tumor biology, and survival. J Pediatr Hematol Oncol. 1999;21(3):181–189. doi:10.1097/00043426-199905000-00005.
   PubMed Web of Science ®Google Scholar
• Ahmed S, Goel S, Khandwala M, Agrawal A, Chang B, Simmons IG. Neuroblastoma with orbital metastasis: ophthalmic presentation and role of ophthalmologists. Eye. 2006;20(4):466–470. doi:https://doi.org/10.1038/sj.eye.6701912.
   PubMed Web of Science ®Google Scholar
• Belgaumi AF, Kauffman WM, Jenkins JJ, Cordoba J, Bowman LC, Santana VM, et al. Blindness in children with neuroblastoma. Cancer. 1997;80(10):1997–2004. doi:10.1002/(SICI)1097-0142(19971115)80:10<1997:AID-CNCR18>3.0.CO;2-T.
   PubMed Web of Science ®Google Scholar
• Johnstone C, Rich SE. Bleeding in cancer patients and its treatment: a review. Ann Palliat Med. 2018;7(2):265–273. doi:10.21037/apm.2017.11.01.
   PubMed Web of Science ®Google Scholar
• Nishida N, Yano H, Nishida T, Kamura T, Kojiro M. Angiogenesis in cancer. Vasc Health Risk Manag. 2006;2(3):213–219. doi:10.2147/vhrm.2006.2.3.213.
   PubMedGoogle Scholar
• Madhumathi DS, Premalata CS, Devi VL, Appaji L, Kumari AB, Padma M, et al. Bone marrow involvement at presentation in pediatric non-haematological small round cell tumours. Indian J Pathol Microbiol. 2007;50(4):886–889.
   PubMedGoogle Scholar
• Khan MF, Falk RH. Amyloidosis. Postgrad Med J. 2001;77(913):686–693. doi:10.1136/pmj.77.913.686.
   PubMed Web of Science ®Google Scholar
• Merlini G, Seldin DC, Gertz MA. Amyloidosis: pathogenesis and new therapeutic options. J Clin Oncol. 2011;29(14):1924–1933. doi:10.1200/JCO.2010.32.2271.
   PubMed Web of Science ®Google Scholar
• Staron A, Zheng L, Doros G, Connors LH, Mendelson LM, Joshi T, et al. Marked progress in AL amyloidosis survival: a 40-year longitudinal natural history study. Blood Cancer J. 2021;11(8):139. doi:https://doi.org/10.1038/s41408-021-00529-w.
   PubMed Web of Science ®Google Scholar
• Choufani EB, Sanchorawala V, Ernst T, Quillen K, Skinner M, Wright DG, et al. Acquired factor X deficiency in patients with amyloid light-chain amyloidosis: incidence, bleeding manifestations, and response to high-dose chemotherapy. Blood. 2001 15;97(6):1885–1887. doi:10.1182/blood.v97.6.1885.
   PubMed Web of Science ®Google Scholar
• Mumford AD, O’Donnell J, Gillmore JD, Manning RA, Hawkins PN, Laffan M. Bleeding symptoms and coagulation abnormalities in 337 patients with AL-amyloidosis. Br J Haematol. 2000;110(2):454–460. doi:10.1046/j.1365-2141.2000.02183.x.
   PubMed Web of Science ®Google Scholar
• Reynolds SB, Maghavani DP, Hashmi H. Acquired factor X deficiency in a patient with multiple myeloma: a rare case highlighting the significance of comprehensive evaluation and the need for antimyeloma therapy for bleeding diathesis. BMJ Case Rep. 2019;12(9):e230249. doi:10.1136/bcr-2019-230249.
   PubMedGoogle Scholar
• Wu B, Pak DM, Smith KD, Shinohara MM. Utility of abdominal skin punch biopsy for detecting systemic amyloidosis. J Cutan Pathol. 2021;48(11):1342–1346. doi:10.1111/cup.14070.
   PubMed Web of Science ®Google Scholar
• Banerjee P, Alam MS, Subramanian N, Kundu D, Koka K, Poonam NS, et al. Orbital and adnexal amyloidosis: thirty years experience at a tertiary eye care center. Indian J Ophthalmol. 2021;69(5):1161–1166. doi:10.4103/ijo.IJO_2528_20.
   PubMed Web of Science ®Google Scholar
• Dammacco R, Merlini G, Lisch W, Kivelä TT, Giancipoli E, Vacca A, et al. Amyloidosis and ocular involvement: an overview. Semin Ophthalmol. 2020;35(1):7–26. doi:10.1080/08820538.2019.1687738.
   PubMed Web of Science ®Google Scholar
• Saper JR. Migraine, migraine variants, and related headaches. Otolaryngol Clin North Am. 1989;22(6):1115–1130. doi:10.1016/S0030-6665(20)31340-2.
   PubMed Web of Science ®Google Scholar
• Burstein R, Noseda R, Borsook D. Migraine: multiple processes, complex pathophysiology. J Neurosci. 2015;35(17):6619–6629. doi:10.1523/JNEUROSCI.0373-15.2015.
   PubMed Web of Science ®Google Scholar
• Puledda F, Messina R, Goadsby PJ. An update on migraine: current understanding and future directions. J Neurol. 2017;264(9):2031–2039. doi:10.1007/s00415-017-8434-y.
   PubMed Web of Science ®Google Scholar
• Jacobs B, Dussor G. Neurovascular contributions to migraine: moving beyond vasodilation. Neuroscience. 2016;338:130–144. doi:10.1016/j.neuroscience.2016.06.012.
   PubMed Web of Science ®Google Scholar
• Cole AJ, Aubé M. Migraine with vasospasm and delayed intracerebral hemorrhage. Arch Neurol. 1990;47(1):53–56. doi:10.1001/archneur.1990.00530010065021.
   PubMedGoogle Scholar
• Cameron C, Kelly S, Hsieh SC, Murphy M, Chen L, Kotb A, et al. Triptans in the acute treatment of migraine: a systematic review and network meta-analysis. Headache. 2015;55(Suppl 4):221–235. doi:10.1111/head.12601.
   PubMed Web of Science ®Google Scholar
• Conti P, D’Ovidio C, Conti C, Gallenga CE, Lauritano D, Caraffa A, et al. Progression in migraine: role of mast cells and pro-inflammatory and anti-inflammatory cytokines. Eur J Pharmacol. 2019;844:87–94. doi:10.1016/j.ejphar.2018.12.004.
   PubMed Web of Science ®Google Scholar
• Onishi A, St Ange K, Dordick JS, Linhardt RJ. Heparin and anticoagulation. Front Biosci (Landmark Ed). 2016;21(7):1372–1392. doi:10.2741/4462.
   PubMedGoogle Scholar
• Seçil Y, Unde C, Beckmann YY, Bozkaya YT, Ozerkan F, Başoğlu M. Blood pressure changes in migraine patients before, during and after migraine attacks. Pain Pract. 2010;10(3):222–227. doi:10.1111/j.1533-2500.2009.00349.x.
   PubMed Web of Science ®Google Scholar
• Wang YF, Wang SJ. Hypertension and migraine: time to revisit the evidence. Curr Pain Headache Rep. 2021;25(9):58. doi:10.1007/s11916-021-00976-x.
   PubMed Web of Science ®Google Scholar
• Yulug B, Hanoglu L, Schabitz WR. Headache and spontaneous glabellar ecchymosis: more than a self-injury behaviour? Psych Clin Neuosci. 2014;69(2):124. doi:10.1111/pcn.12220.
   PubMed Web of Science ®Google Scholar
• Ngnitewe Massa R, Minutello K, Mesfin FB. Neuroanatomy, CAvernous SinuS. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; July 26, 2021. https://www.ncbi.nlm.nih.gov/books/NBK459244/. Accessed January 2022.
   Google Scholar
• Rootman J. Vascular malformations of the orbit: hemodynamic concepts. Orbit. 2003;22(2):103–120. doi:10.1076/orbi.22.2.103.14311.
   PubMedGoogle Scholar
• Rubboli A, Becattini C, Verheugt FW. Incidence, clinical impact and risk of bleeding during oral anticoagulation therapy. World J Cardiol. 2011;3(11):351–358. doi:10.4330/wjc.v3.i11.351.
   PubMedGoogle Scholar
• Neutze D, Roque J. Clinical evaluation of bleeding and bruising in primary care. Am Fam Physician. 2016 15;93(4):279–286.
   PubMed Web of Science ®Google Scholar
• Bakchoul T, Marini I. Drug-associated thrombocytopenia. Hematology Am Soc Hematol Educ Program. 2018;2018(1):576–583. doi:10.1182/asheducation-2018.1.576.
   PubMedGoogle Scholar
• Anzalone CL, Cohen PR, Kurzrock R, Cortes JE. Imatinib-induced postoperative periorbital purpura: GASP (Gleevec-Associated Surgical Purpura) in a woman with imatinib-treated chronic myelogenous leukemia. Dermatol Online J. 2014;20(1):21242. doi:10.5070/D3201021242.
   PubMedGoogle Scholar