Association of transcription factor 4 (TCF4) gene mRNA level with schizophrenia, its psychopathology, intelligence and cognitive impairments

References

• Ayalew, M., Le-Niculescu, H., Levey, D.F., Jain, N., Changala, B., Patel, S.D., … Niculescu, A.B. (2012). Convergent functional genomics of schizophrenia: from comprehensive understanding to genetic risk prediction. Molecular Psychiatry, 17, 887–905. doi:10.1038/mp.2012.37.
   PubMed Web of Science ®Google Scholar
• Aylward, E., Walker, E., & Bettes, B. (1984). Intelligence in schizophrenia: meta-analysis of the research. Schizophrenia Bulletin, 10, 430–459. doi:10.1093/schbul/10.3.430
   PubMed Web of Science ®Google Scholar
• Carter, C.S., Mintun, M., Nichols, T., & Cohen, J.D. (1997). Anterior cingulate gyrus dysfunction and selective attention deficits in schizophrenia: [15O]H2O PET study during single-trial stroop task performance. American Journal of Psychiatry, 154, 1670–1675. doi:10.1176/ajp.154.12.1670
   PubMed Web of Science ®Google Scholar
• Corfas, G., Roy, K., & Buxbaum, J.D. (2004). Neuregulin 1-erbB signaling and the molecular/cellular basis of schizophrenia. Nature Neuroscience, 7, 575–580. doi:10.1038/nn1258
   PubMed Web of Science ®Google Scholar
• Crow, T. (1981). Positive and negative schizophrenia symptoms and the role of dopamine. The British Journal of Psychiatry, 139, 251–254.
   PubMed Web of Science ®Google Scholar
• de Pontual, L., Mathieu, Y., Golzio, C., Rio, M., Malan, V., Boddaert, N., … Amiel, J. (2009). Mutational, functional, and expression studies of the TCF4 gene in Pitt-Hopkins syndrome. Human Mutation, 30, 669–676. doi:10.1002/humu.20935
   PubMed Web of Science ®Google Scholar
• Demeter, E., Guthrie, S.K., Taylor, S.F., Sarter, M., & Lustig, C. (2013). Increased distractor vulnerability but preserved vigilance in patients with schizophrenia: evidence from a translational sustained attention task. Schizophrenia Research, 144, 136–141. doi:10.1016/j.schres.2013.01.003
   PubMed Web of Science ®Google Scholar
• Diamond, A. (2013). Executive functions. Annual Review of Psychology, 64, 135–168. doi:10.1146/annurev-psych-113011-143750
   PubMed Web of Science ®Google Scholar
• Edwards, A.C., Bigdeli, T.B., Docherty, A.R., Bacanu, S., Lee, D., De Candia, T.R., … Wormley, B.K. (2016). Meta-analysis of positive and negative symptoms reveals schizophrenia modifier genes. Schizophrenia Bulletin, 42, 279–287. doi: 10.1093/schbul/sbv119
   PubMed Web of Science ®Google Scholar
• Emamian, E.S., Hall, D., Birnbaum, M.J., Karayiorgou, M., & Gogos, J.A. (2004). Convergent evidence for impaired AKT1-GSK3β signaling in schizophrenia. Nature Genetics, 36, 131–137.
   PubMed Web of Science ®Google Scholar
• Everett, J., Lavoie, K., Gagnon, J.F., & Gosselin, N. (2001). Performance of patients with schizophrenia on the Wisconsin Card Sorting Test (WCST). Journal of Psychiatry and Neuroscience, 26, 123–130. Retrieved from http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1407748/
   PubMed Web of Science ®Google Scholar
• Friedman, N.P. (2016). Research on individual differences in executive functions. Linguistic Approaches to Bilingualism, 6, 535–548. doi:10.1075/lab.15041.fri
   PubMed Web of Science ®Google Scholar
• Giurgea, I., Missirian, C., Cacciagli, P., Whalen, S., Fredriksen, T., Gaillon, T., … Moncla, A. (2008). TCF4 deletions in Pitt-Hopkins Syndrome. Human Mutation, 29, E242–E251. doi:10.1002/humu.20859
   PubMed Web of Science ®Google Scholar
• Goghari, V.M., Macdonald, A.W., & Sponheim, S.R. (2014). Relationship between prefrontal gray matter volumes and working memory performance in schizophrenia: a family study. Schizophrenia Research, 153, 113–121. doi:10.1016/j.schres.2014.01.032
   PubMed Web of Science ®Google Scholar
• Golden, C.J., & Freshwater, S.M. (1978). Stroop color and word test. Age, 15, 90.
   Google Scholar
• Grace, A.A. (2016). Dysregulation of the dopamine system in the pathophysiology of schizophrenia and depression. Nature Reviews Neuroscience, 17, 524–532. doi:10.1038/nrn.2016.57
   PubMed Web of Science ®Google Scholar
• Green, M.F., Kern, R.S., Braff, D.L., & Mintz, J. (2000). Neurocognitive deficits and functional outcome in schizophrenia: are we measuring the “right stuff”. Schizophr Bull, 26, 119–136.
   PubMed Web of Science ®Google Scholar
• Gur, R.E., Cowell, P.E., Latshaw, A., Turetsky, B.I., Grossman, R.I., Arnold, S.E., …, Gur, R.C. (2000). Reduced dorsal and orbital prefrontal gray matter volumes in schizophrenia. Archives of General Psychiatry, 57, 761–768. doi:10.1001/archpsyc.57.8.761
   PubMed Web of Science ®Google Scholar
• Hakak, Y., Walker, J.R., Li, C., Wong, W.H., Davis, K.L., Buxbaum, J.D., … Fienberg, A.A. (2001). Genome-wide expression analysis reveals dysregulation of myelination-related genes in chronic schizophrenia. Proceedings of the National Academy of Sciences, 98, 4746–4751.
   PubMed Web of Science ®Google Scholar
• Hirayasu, Y., Tanaka, S., Shenton, M.E., Salisbury, D.F., DeSantis, M.A., Levitt, J.J., … McCarley, R.W. (2001). Prefrontal gray matter volume reduction in first episode schizophrenia. Cerebral Cortex, 11, 374–381.
   PubMed Web of Science ®Google Scholar
• Hodges, J.R. (2007). Cognitive Assessment for Clinicians (2 ed.). Oxford, UK: Oxford University Press.
   Google Scholar
• http://www.nature.com/nature/journal/v511/n7510/abs/nature13595.html#supplementary-information. Retrieved from http://dx.doi.org/10.1038/nature13595
   Google Scholar
• Hui, L., Rao, W.W., Yu, Q., Kou, C., Wu, J.Q., He, J.C., … Zhang, X.Y. (2015). TCF4 gene polymorphism is associated with cognition in patients with schizophrenia and healthy controls. Journal of Psychiatric Research, 69, 95–101. doi:10.1016/j.jpsychires.2015.07.022
   PubMed Web of Science ®Google Scholar
• Hunsley, J., & Lee, C.M. (2014). Introduction to Clinical Psychology (2 ed.). Canada: Wiley.
   Google Scholar
• Kaufman, A.S., & Lichtenberger, E.O. (2005). Assessing Adolescent and Adult Intelligence, (3 ed.). Allyn and Bacon.
   Google Scholar
• Kay, S.R., Flszbein, A., & Opfer, L.A. (1987). The positive and negative syndrome scale (PANSS) for schizophrenia. Schizophrenia. Bulletin, 13, 261. doi:10.1093/schbul/13.2.261
   Google Scholar
• Keefe, R.S., & Harvey, P.D. (2012). Cognitive impairment in schizophrenia. In: Novel antischizophrenia treatments (pp. 11–37). Berlin, Heidelberg: Springer.
   Google Scholar
• Kochunov, P., Charlesworth, J., Winkler, A., Hong, L.E., Nichols, T.E., Curran, J.E., … Johnson, M. (2013). Transcriptomics of cortical gray matter thickness decline during normal aging. NeuroImage, 82, 273–283. doi: 10.1016/j.neuroimage.2013.05.066
   PubMed Web of Science ®Google Scholar
• Kohli, A., & Kaur, M. (2006). Wisconsin Card Sorting Test: Normative data and experience. Indian Journal of Psychiatry, 48, 181–184. doi:10.4103/0019-5545.31582
   PubMedGoogle Scholar
• Kremen, W.S., Buka, S.L., Seidman, L.J., Goldstein, J.M., Koren, D., & Tsuang, M.T. (1998). IQ decline during childhood and adult psychotic symptoms in a community sample: a 19-year longitudinal study. American Journal of Psychiatry, 155, 672–677. doi:10.1176/ajp.155.5.672
   PubMed Web of Science ®Google Scholar
• Kremen, W.S., Seidman, L.J., Faraone, S.V., Toomey, R., & Tsuang, M.T. (2004). Heterogeneity of schizophrenia: a study of individual neuropsychological profiles. Schizophr Res, 71, 307–321. doi:10.1016/j.schres.2004.02.022
   PubMed Web of Science ®Google Scholar
• Kurian, S., Le-Niculescu, H., Patel, S., Bertram, D., Davis, J., Dike, C., … Caligiuri, M. (2011). Identification of blood biomarkers for psychosis using convergent functional genomics. Molecular Psychiatry, 16, 37–58. doi: 10.1038/mp.2009.117
   PubMed Web of Science ®Google Scholar
• Lee, J., & Park, S. (2005). Working memory impairments in schizophrenia: a meta-analysis. Journal of Abnormal Psychology, 114, 599. doi:10.1037/0021-843X.114.4.599
   PubMed Web of Science ®Google Scholar
• Lennertz, L., Rujescu, D., Wagner, M., Frommann, I., Schulze-Rauschenbach, S., Schuhmacher, A., Mössner, R. (2011). Novel schizophrenia risk gene TCF4 influences verbal learning and memory functioning in schizophrenia patients. Neuropsychobiology, 63, 131–136. Retrieved from http://www.karger.com/DOI/10.1159/000317844
   PubMed Web of Science ®Google Scholar
• McCullumsmith, R.E., Clinton, S.M., & Meador-Woodruff, J.H. (2004). Schizophrenia as a disorder of neuroplasticity. International Review of Neurobiology, 59, 19–45. doi:10.1016/s0074-7742(04)59002-5
   PubMed Web of Science ®Google Scholar
• McGrath, J., Saha, S., Chant, D., & Welham, J. (2008). Schizophrenia: A concise overview of incidence, prevalence, and mortality. Epidemiologic Reviews, 30, 67–76. doi:10.1093/epirev/mxn001
   PubMed Web of Science ®Google Scholar
• Mudge, J., Miller, N.A., Khrebtukova, I., Lindquist, I.E., May, G.D., Huntley, J.J., … Farmer, A.D. (2008). Genomic convergence analysis of schizophrenia: mRNA sequencing reveals altered synaptic vesicular transport in post-mortem cerebellum. PloS One, 3, e3625. doi: 10.1371/journal.pone.0003625
   PubMed Web of Science ®Google Scholar
• Nour, M.M., & Howes, O.D. (2015). Interpreting the neurodevelopmental hypothesis of schizophrenia in the context of normal brain development and ageing. Proceedings of the National Academy of Sciences, 112, E2745–E2745. doi:10.1073/pnas.1502170112
   PubMed Web of Science ®Google Scholar
• Ochoa, S., Usall, J., Cobo, J., Labad, X., & Kulkarni, J. (2012). Gender Differences in schizophrenia and first-episode psychosis: a comprehensive literature review. Schizophrenia Research and Treatment, 2012, 9. doi:10.1155/2012/916198
   Google Scholar
• Park, S., & Gooding, D.C. (2014). Working memory impairment as an endophenotypic marker of a schizophrenia diathesis. Schizophrenia Research: Cognition, 1, 127–136. doi:10.1016/j.scog.2014.09.005
   PubMedGoogle Scholar
• Pol, H.E.H., Schnack, H.G., Bertens, M.G., van Haren, N.E., van der Tweel, I., Staal, W.G., … Kahn, R.S. (2002). Volume changes in gray matter in patients with schizophrenia. American Journal of Psychiatry, 159, 244–250. doi:10.1176/appi.ajp.159.2.244
   PubMed Web of Science ®Google Scholar
• Prentice, K.J., Gold, J.M., & Buchanan, R.W. (2008). The Wisconsin Card Sorting impairment in schizophrenia is evident in the first four trials. Schizophrenia Research, 106, 81–87. doi:10.1016/j.schres.2007.07.015
   PubMed Web of Science ®Google Scholar
• Quednow, B.B., Brzózka, M.M., & Rossner, M.J. (2014). Transcription factor 4 (TCF4) and schizophrenia: integrating the animal and the human perspective. Cellular and Molecular Life Sciences, 71, 2815–2835. doi:10.1007/s00018-013-1553-4
   PubMed Web of Science ®Google Scholar
• Quednow, B.B., Ettinger, U., Mossner, R., Rujescu, D., Giegling, I., Collier, D.A., … Kumari, V. (2011). The schizophrenia risk allele C of the TCF4 rs9960767 polymorphism disrupts sensorimotor gating in schizophrenia spectrum and healthy volunteers. Journal of Neuroscience, 31, 6684–6691. doi:10.1523/jneurosci.0526-11.2011
   PubMed Web of Science ®Google Scholar
• Ross, S.E., Greenberg, M.E., & Stiles, C.D. (2003). Basic helix-loop-helix factors in cortical development. Neuron, 39, 13–25. doi:10.1016/S0896-6273(03)00365-9
   PubMed Web of Science ®Google Scholar
• Schizophrenia Working Group of the Psychiatric Genomics, C. (2014). Biological insights from 108 schizophrenia-associated genetic loci. [Article]. Nature, 511, 421–427. doi:10.1038/nature13595
   PubMed Web of Science ®Google Scholar
• Seelye, A.M., Howieson, D.B., Wild, K.V., Moore, M.M., & Kaye, J.A. (2009). Wechsler Memory Scale–III Faces test performance in patients with mild cognitive impairment and mild Alzheimer’s disease. Journal of Clinical and Experimental Neuropsychology, 31, 682–688. doi:10.1080/13803390802484763
   PubMed Web of Science ®Google Scholar
• Selvaraj, S., Arnone, D., Cappai, A., & Howes, O. (2014). Alterations in the serotonin system in schizophrenia: A systematic review and meta-analysis of postmortem and molecular imaging studies. Neuroscience and Biobehavioral Reviews, 45, 233–245. doi:10.1016/j.neubiorev.2014.06.005
   PubMed Web of Science ®Google Scholar
• Singh, S., Aich, T.K., & Bhattarai, R. (2017). Wisconsin Card Sorting Test performance impairment in schizophrenia: An Indian study report. Indian Journal of Psychiatry, 59, 88–93. doi:10.4103/0019-5545.204440
   PubMed Web of Science ®Google Scholar
• Sullivan, P.F., Kendler, K.S., & Neale, M.C. (2003). Schizophrenia as a complex trait: Evidence from a meta-analysis of twin studies. Archives of General Psychiatry, 60, 1187–1192. doi:10.1001/archpsyc.60.12.1187
   PubMed Web of Science ®Google Scholar
• Tamlyn, D., McKenna, P.J., Mortimer, A.M., Lund, C.E., Hammond, S., & Baddeley, A.D. (2009). Memory impairment in schizophrenia: its extent, affiliations and neuropsychological character. Psychological Medicine, 22, 101–115. doi:10.1017/S0033291700032773
   Google Scholar
• Ward, R.D., Winiger, V., Higa, K.K., Kahn, J.B., Kandel, E.R., Balsam, P.D., & Simpson, E.H. (2015). “The impact of motivation on cognitive performance in an animal model of the negative and cognitive symptoms of schizophrenia”: Correction to Ward et al. (2015).
   Google Scholar
• Wirgenes, K.V., Sonderby, I.E., Haukvik, U.K., Mattingsdal, M., Tesli, M., Athanasiu, L., … Andreassen, O.A. (2012). TCF4 sequence variants and mRNA levels are associated with neurodevelopmental characteristics in psychotic disorders. [Original Article]. Translational Psychiatry, 2, e112. doi:10.1038/tp.2012.39
   PubMed Web of Science ®Google Scholar
• Woodberry, K.A., Giuliano, A.J., & Seidman, L.J. (2008). Premorbid IQ in schizophrenia: a meta-analytic review. American Journal of Psychiatry, 165, 579–587. doi:10.1176/appi.ajp.2008.07081242.
   PubMed Web of Science ®Google Scholar
• Zhu, X., Gu, H., Liu, Z., Xu, Z., Chen, X., Sun, X., … Chen, C. (2013). Associations between TCF4 gene polymorphism and cognitive functions in schizophrenia patients and healthy controls. Neuropsychopharmacology, 38, 683–689. http://www.nature.com/npp/journal/v38/n4/suppinfo/npp2012234s1.html
   PubMed Web of Science ®Google Scholar
• Zweier, C., Peippo, M.M., Hoyer, J., Sousa, S., Bottani, A., Clayton-Smith, J., … Rauch, A. (2007). Haploinsufficiency of TCF4 causes syndromal mental retardation with intermittent hyperventilation (Pitt-Hopkins Syndrome). The American Journal of Human Genetics, 80, 994–1001. doi:http://10.1086/515583
   PubMed Web of Science ®Google Scholar