92
Views
43
CrossRef citations to date
0
Altmetric
Research Article

LONG-TERM INHALATION OF DIESEL EXHAUST AFFECTS CYTOKINE EXPRESSION IN MURINE LUNG TISSUES: COMPARISON BETWEEN LOW- AND HIGH-DOSE DIESEL EXHAUST EXPOSURE

, , , &
Pages 493-506 | Published online: 02 Jul 2009

  • Scarlett JF, Abbott KJ, Peacock JL, Strachan DP, Andereson HR: Acute effects of summer air pollution on respiratory function in primary school children in southern England. Thorax. 1996;51:1109-1114.
  • Ackermann-Liebrich U, Leuenberger P, Schwanz J, Schindler A., Monn A., Bolognini G, Bongard JP, Brandli O, Domenighetti G, Elsasser S, Grize L, Karrer W, Keller R, Keller-Wossidlo H, Kunzli N, Martin BW, Medici TC, Perrunchoud AP, Schoni MH, Tschopp JM, Villiger B, Wuthrich B, Zellweger JP, Zemp E: Lung function and long term air pollutants in Switzerland. Study on air pollution and lung disease in adults (SAPALDIA) team. Am J Respir Crit Care Med. 1997;155:122-129.
  • Schvaltz J: Particulate air pollution and chronic respiratory disease. Environ Res. 1993;62:71-73.
  • Thurston GD, Ito K, Hayes CG, Bates DV, Lippmann M: Respiratory hospital admissions and summertime haze air pollution in Toronto, Ontario: consideration of the role of acid aerosols. Environ Res. 1994;65:271-290.
  • Sunyer J, Saez M, Murillo C, Castellsague J, Martinez F, Anto JM: Air pollution, and emergency room admissions for chronic obstructive pulmonary disease: a 5-year study. Am J Epidemiol. 1993;137:701-705.
  • Dockery DW, Pope CA III: Acute respiratory effects of paniculate air pollution. Annu Rev Public Health. 1994;15:107-132.
  • Schwarte J: Air pollution and hospital admissions for the elderly in Birmingham, AL. Am J Epidemiol. 1994;139:589-598.
  • Dockery DW, Pope CA m, Xu X, Spengler JD, Ware JH, Fay ME, Ferris BG Jr, Speizer FE: An association between air pollution and mortality in six U.S. cities. N Engl J Med. 1993;329:1753-1759.
  • Burnett RT, Dales RE, Krewski D, Vincent R, Dann T, Brook JR: Associations between ambient particulate sulphate and admissions to Ontario hospitals for cardiac and respiratory diseases. Am J Epidemiol. 1995;142:15-22.
  • Samet JM, Dominici F, Curriero FC, Coursac I, Zeger SL: Fine Particulate air pollution and mortality in 20 U.S. cities, 1987-1994. N Engl J Med. 2000;343:1742-1749.
  • Steerenberg PA, Zonnenberg JA, Dormans JA., Joon PN, Wouters IM, van Bree L, Scheepers PT, Van Loveren H: Diesel exhaust particles induced release of interleukin 6 and 8 by (primed) human bronchial epithelial cells (BEAS 2B) in vitro. Exp Lung Res. 1998;24:85-100.
  • Ohtoshi T, Takizawa H, Okazaki H, Kawasaki S, Takeuchi N, Ohta K, Ito K: Diesel exhaust particles stimulate human airway epithelial cells to produce cytokines relevant to airway inflammation in vitro. J Allergy din Immunol. 1998;101(6 Pt 1):778-785.
  • Nel AE, Diaz-Sanchez D, Ng D, Hiura T, Saxon A: Enhancement of allergic inflammation by the interaction between diesel exhaust particles and the immune system. J Allergy Clin Immunol. 1998;102(4 Pt 1):539-554. (Review.)
  • Takizawa H, Ohtoshi T, Kawasaki S, Kohyama T, Desaki M, Kasama T, Kobayashi K, Nakahara K, Yamamoto K, Matsushima K, Kudoh S: Diesel exhaust particles induce NF-kappa B activation in human bronchial epithelial cells in vitro: importance in cytokine transcription. J Immunol. 1999;162:4705-4711.
  • Boland S, Baeza-Squiban A, Fournier T, Houcine O, Gendron MC, Chewier M. Jouvenot G, Coste A, Aubier M, Marano F: Diesel exhaust particles are taken up by human airway epithelial cells in vitro and alter cytokine production. Am J Physiol. 1999;276(4 Pt 1):1,604-613.
  • Abe S, Takizawa H, Sugawara I, Kudoh S: Diesel exhaust (DE)-induced cytokine expression in human bronchial epithelial cells: a study with a new cell exposure system to freshly generated DE in vitro. Am J Respir Cell Mol Biol. 2000;22:296-303.
  • Hashimoto S, Gon Y, Takeshita I, Matsumoto K, Jibiki I, Takizawa H, Kudoh S, Hone T: Diesel exhaust particles activate p38 MAP kinase to produce interleukin 8 and RANTES by human bronchial epithelial cells and N-acetylcysteine attenuates p38 MAP kinase activation. Am J Respir Grit Care Med. 2000;161:280-285.
  • Yang HM, Barger MW, Castranova V, Ma JK, Yang JJ, Ma JY: Effects of diesel exhaust particles (DEP), carbon black, and silica on macrophage responses to lipopolysaccharide evidence of DEP suppression of macrophage activity. J Toxicol Environ Health A. 1999;8:261-278.
  • Yang HM, Ma JY, Castranova V, Ma JK: Effects of diesel exhaust particles on the release of interleukin-1 and tumor necrosis factor-alpha from rat alveolar macrophages. Exp Lung Res. 1997;23:269-284.
  • Iwai K, Higuchi K, Udagawa T, Ohtomo K, Kawabata Y: Lung tumor induced by long-term inhalation or intratracheal instillation of diesel exhaust particles. Exp Toxicol Pathol. 1997;49:393-401.
  • Le Prieur E, Vaz E, Bion A, Dionnet F, Morin JP: Toxicity of diesel engine exhausts in an in vitro model of lung slices in biphasic organotypic culture: induction of a proinflammatory and apoptotic response. Arch Toxicol. 2000;74:460-466.
  • Kaneko H, Yamada H, Mizuno S, Udagawa T, Kazumi Y, Sekikawa K, Sugawara I: Role of tumor necrosis factor-alpha in Mycobacteriuminduced granuloma formation in tumor necrosis factor-alpha-deficient mice. Lab Invest. 1999;79:379-386.
  • Conn CA, McClellan JL, Maassab HF, Smith CW, Majde JA, Kluger MJ: Cytokines and acute phase response to influenza virus in mice. Am J Physiol. 1995;268:R78-R84.
  • Cooper AM, Dalton DK, Stewart TA, Griffin JP, Russel DG, Orme IM: Disseminated tuberculosis in interferon ? gene-deficient mice. J Exp Med. 1993;178:2243-2247.
  • Hahon N, Booth JA, Green F, Lewis TR: Influenza virus infection in mice after exposure to coal dust and diesel engine emissions. Environ Res. 1985;37:44-60.
  • Hatch GE, Boykin E, Graham JA, Lewtas J, Pott F, Loud K, Mumford JL: Inhalable particles and pulmonary host defense: in vivo and in vitro effects of ambient air and combustion particles. Environ Res. 1985;36:67-80.
  • van der Poll T, Marchant A, Keogh C, Goldman M, Lowry S: Interleukin-10 impairs host defense in murine pneumococcal pneumonia. J Infect Dis. 1996;174:994-1000.
  • Sagai M, Furuyama A, Ichinose T: Biological effects of diesel exhaust particles (DEP), UI: pathogenesis of asthma-like symptoms in mice. Free Radie Biol Med. 1996;21:199-209.
  • Takano H, Yoshikawa T, Ichinose T, Miyabara Y, Imaoka K, Sagai M: Diesel exhaust particles enhance antigen-induced airway inflammation and local cytokine expression in mice. Am J Respir Crit Care Med. 1997;156:36-42.
  • Miyabara Y, Takano H, Ichinose T, Lim H, Sagai M: Diesel exhaust enhances allergic airway inflammation and hyperresponsiveness in mice. Am J Respir Crit Care Med. 1998;157:1138-1144.
  • Diaz-Sanchez D, Garcia MP, Wang M. Jyrala M, Saxon A: Nasal challenge with diesel exhaust particles can induce sensitization to a neoallergen in the human mucosa. J Allergy Clin Immunol. 1999;104:1183-1188.
  • Fujimaki H, Nohara O, Ichinose T, Watanabe N, Saito S: IL-4 production in mediastinal lymph node cells in mice intratracheally instilled with diesel exhaust particles and antigen. Toxicology 1994;92:261-268.
  • Wang M, Saxon A, Diaz-Sanchez: Early IL-4 production driving Th-2 differentiation in vivo allergic model is mast cell derived, clin Immunol. 1999;90:47-54
  • Bommel H, Li-Weber M, Serfling E, Duschl A: The environmental pollutant Pyrene induces the production of IL-4. J Allergy Clin Immunol. 2000;105:796-802.
  • Nikula KJ, Avila KJ, Griffith WC, Mauderly JL: Sites of particle retention and lung tissue responses to chronically inhaled diesel exhaust and coal dust in rats and cynomolgus monkeys. Environ Health Perspect. 1997;105(Suppl 5):1231-1234.
  • Strom KA: Response of pulmonary cellular defenses to the inhalation of high concentrations of diesel exhaust J Toxicol Environ Health. 1984;13:919-944.
  • Otterbein LE, Bach FH, Alam J, Scares M, Tao LH, Wysk M, Davis RJ, Flavell RA, Choi AM: Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway. Nat Med. 2000;6:422-428.
  • Devalia JL, Campbell AM, Sapsford RJ, Rusznak C, Quint D, Godard P, Bousquet J, Davies RJ: Effect of nitrogen dioxide on synthesis of inflammatory cytokines expressed by human bronchial epithelial cells in vitro. Am J Respir Cell Mol Biol. 1993;9:271-278.
  • Erroi A, Pagnani P, Sironi M, Salmona M: In vivo exposure to NO2 reduces TNF and IL-6 production by endotoxin-stimulated alveolar macrophages. Am J Physiol. 1996;271:132-138.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.