References
- Limberis M, Anson DS, Fuller M, Parsons DW. Recovery of airway cystic fibrosis transmembrane conductance regulator function in mice with cystic fibrosis after single-dose lentivirus-mediated gene transfer. Hum Gene Ther. 2002;13(16):1961–70. doi:https://doi.org/10.1089/10430340260355365. PMID:12427306.
- Oakland M, Sinn PL, McCray PB, Jr. Advances in cell and gene-based therapies for cystic fibrosis lung disease. Mol Ther. 2012;20(6):1108–15. doi:https://doi.org/10.1038/mt.2012.32. PMID:22371844.
- Castellani S, Conese M. Lentiviral vectors and cystic fibrosis gene therapy. Viruses. 2010;2(2):395–412. doi:https://doi.org/10.3390/v2020395. PMID:21994643.
- Parsons DW. Airway gene therapy and cystic fibrosis. J Paediatr Child Health. 2005;41(3):94–6. doi:https://doi.org/10.1111/j.1440-1754.2005.00556.x. PMID:15790317.
- Zabner J, Ramsey BW, Meeker DP, et al. Repeat administration of an adenovirus vector encoding cystic fibrosis transmembrane conductance regulator to the nasal epithelium of patients with cystic fibrosis. J Clin Invest. 1996;97(6):1504–11. doi:https://doi.org/10.1172/JCI118573. PMID:8617884.
- Buckley SM, Howe SJ, Sheard V, et al. Lentiviral transduction of the murine lung provides efficient pseudotype and developmental stage-dependent cell-specific transgene expression. Gene Ther. 2008;15(16):1167–75. doi:https://doi.org/10.1038/gt.2008.74. PMID:18432275.
- Ziady AG, Davis PB. Current prospects for gene therapy of cystic fibrosis. Curr Opin Pharmacol. 2006;6(5):515–21. doi:https://doi.org/10.1016/j.coph.2006.04.008. PMID:16890018.
- Grubb BR, Boucher RC. Pathophysiology of gene-targeted mouse models for cystic fibrosis. Physiol Rev. 1999;79(1 Suppl):S193–214. PMID:9922382.
- Cmielewski P, Anson DS, Parsons DW. Lysophosphatidylcholine as an adjuvant for lentiviral vector mediated gene transfer to airway epithelium: effect of acyl chain length. Respir Res. 2010;11:84. doi:https://doi.org/10.1186/1465-9921-11-84. PMID:20569421.
- Stocker AG, Kremer KL, Koldej R, Miller DS, Anson DS, Parsons DW. Single-dose lentiviral gene transfer for lifetime airway gene expression. J Gene Med. 2009;11(10):861–7. doi:https://doi.org/10.1002/jgm.1368. PMID:19634193.
- Cmielewski P, Donnelley M, Parsons DW. Long-term therapeutic and reporter gene expression in lentiviral vector treated cystic fibrosis mice. J Gene Med. 2014;16(9–10):291–9. doi:https://doi.org/10.1002/jgm.2778. PMID:25130650.
- Donnelley M, Morgan KS, Siu KK, Parsons DW. Variability of in vivo fluid dose distribution in mouse airways is visualized by high-speed synchrotron X-ray imaging. J Aerosol Med Pulm Drug Deliv. 2013;26(5):307–16. doi:https://doi.org/10.1089/jamp.2012.1007. PMID:23298238.
- Donnelley M, Siu KK, Jamison RA, Parsons DW. Synchrotron phase-contrast X-ray imaging reveals fluid dosing dynamics for gene transfer into mouse airways. Gene Ther. 2012;19(1):8–14. doi:https://doi.org/10.1038/gt.2011.80. PMID:21654825.
- Liu C, Wong E, Miller D, Smith G, Anson D, Parsons D. Lentiviral airway gene transfer in lungs of mice and sheep: successes and challenges. J Gene Med. 2010;12(8):647–58. PMID:20635320.
- Das S, MacDonald K, Chang HYS, Mitzner W. A Simple Method of Mouse Lung Intubation. Jove-Journal of Visualized Experiments. 2013(73):e50318.
- Cmielewski P, Farrow N, Donnelley M, et al. Transduction of ferret airway epithelia using a pre-treatment and lentiviral gene vector. BMC Pulm Med. 2014;14:183. doi:https://doi.org/10.1186/1471-2466-14-183. PMID:25413892.
- MacDonald KD, Chang HY, Mitzner W. An improved simple method of mouse lung intubation. J Appl Physiol (1985). 2009;106(3):984–7. doi:https://doi.org/10.1152/japplphysiol.91376.2008. PMID:19150857.
- Griesenbach U, Alton EW. Expert opinion in biological therapy: update on developments in lung gene transfer. Expert Opin Biol Ther. 2013;13(3):345–60. doi:https://doi.org/10.1517/14712598.2013.735656. PMID:23289747.
- Naldini L, Blomer U, Gallay P, et al. In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector. Science. 1996;272(5259):263–7. doi:https://doi.org/10.1126/science.272.5259.263. PMID:8602510.
- Sinn PL, Burnight ER, Hickey MA, Blissard GW, McCray PB, Jr. Persistent gene expression in mouse nasal epithelia following feline immunodeficiency virus-based vector gene transfer. J Virol. 2005;79(20):12818–27. doi:https://doi.org/10.1128/JVI.79.20.12818-12827.2005. PMID:16188984.
- Wang G, Slepushkin V, Zabner J, et al. Feline immunodeficiency virus vectors persistently transduce nondividing airway epithelia and correct the cystic fibrosis defect. J Clin Invest. 1999;104(11):R55–62. doi:https://doi.org/10.1172/JCI8390. PMID:10587528.
- Rock JR, Randell SH, Hogan BL. Airway basal stem cells: a perspective on their roles in epithelial homeostasis and remodeling. Dis Model Mech. 2010;3(9–10):545–56. doi:https://doi.org/10.1242/dmm.006031. PMID:20699479.
- Rawlins EL, Hogan BL. Ciliated epithelial cell lifespan in the mouse trachea and lung. Am J Physiol Lung Cell Mol Physiol. 2008;295(1):L231–4. doi:https://doi.org/10.1152/ajplung.90209.2008. PMID:18487354.
- Rawlins EL, Hogan BL. Epithelial stem cells of the lung: privileged few or opportunities for many? Development. 2006;133(13):2455–65. doi:https://doi.org/10.1242/dev.02407. PMID:16735479.