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Review

Tuberculosis in the 21th century: Current status of diagnostic methods

, ORCID Icon, , , &
Pages 352-360 | Received 05 Jun 2018, Accepted 05 Nov 2018, Published online: 19 Jan 2019

References

  • Galagan JE. Genomic insights into tuberculosis. Nat Rev Genet. 2014;15:307–320. doi:10.1038/nrg3664.
  • Warner DF, Koch A, Mizrahi V. Diversity and disease pathogenesis in Mycobacterium tuberculosis. Trends Microbiol. 2015;23(1):14–21. doi:10.1016/j.tim.2014.10.005.
  • World Health Organization. Global Tuberculosis Report 2018. ISBN 978-92-4-156564-6
  • Siddiqi S, Ahmed A, Asif S, et al. Direct drug susceptibility testing of mycobacterium tuberculosis for rapid detection of multidrug resistance using the Bactec MGIT 960 System: A Multicenter Study. J Clin Microbiol. 2012;50(2):435–440. doi:10.1128/JCM.05188-11.
  • McNerney R, Cunningham J, Hepple P, Zumla A. New tuberculosis diagnostics and rollout. Int J Infect Dis. 2015;32:81–86. doi:10.1016/j.ijid.2015.01.012.
  • Fogel N. Tuberculosis: A disease without boundaries. Tuberculosis. 2015;95(5):527–531. doi:10.1016/j.tube.2015.05.017.
  • Comas I, Coscolla M, Luo T, et al. Out-of-Africa migration and Neolithic co-expansion of Mycobacterium tuberculosis with modern humans. Nat Genet. 2013;45(10):1176–1182. doi:10.1038/ng.2744.
  • George R, Cavalcante R, Carvalho Jr C, Marques E, Waugh JB, Unlap MT. Use of siRNA molecular beacons to detect and attenuate mycobacterial infection in macrophages. World J Exp Med. 2015;5(3):164–181. doi:10.5493/wjem.v5.i3.164.
  • Abbas K, Fausto N, Aster J. R Infectious Diseases. Robbins and Cotran pathologic basis of disease. Pennsylvania: Elsevier; 2010.
  • Zumla A, Nahid P, Cole ST. Advances in the development of new tuberculosis drugs and treatment regimens. Nat Rev Drug Discov. 2013;12:388–404. doi:10.1038/nrd4001.
  • Gagneux S. Genetic diversity in mycobacterium tuberculosis BT - Pathogenesis of Mycobacterium tuberculosis and its Interaction with the Host Organism. In: Pieters J, McKinney JD, eds. Berlin, Heidelberg: Springer Berlin Heidelberg; 2013:1–25. doi:10.1007/82_2013_329.
  • Eva B, Philip S, Nadine H, Torsten S, ST P, Roland B. A glimpse into the past and predictions for the future: the molecular evolution of the tuberculosis agent. Mol Microbiol. 2014;93(5):835–852. doi:10.1111/mmi.12720.
  • Pérez-Lago L, Comas I, Navarro Y, et al. Whole genome sequencing analysis of intrapatient microevolution in mycobacterium tuberculosis: Potential impact on the inference of tuberculosis transmission. J Infect Dis. 2014;209(1):98–108.
  • Olivier I, Loots D. An overview of tuberculosis treatments and diagnostics. What role could metabolomics play? J Cell Tissue Res. 2011;11:2655–2671.
  • WHO. Diagnostics for tuberculosis, global demand and market potential. Geneva, Switzerland: WHO; 2006:33–49.
  • Getahun H, Harrington M, O’Brien R, Nunn P. Diagnosis of smear-negative pulmonary tuberculosis in people with HIV infection or AIDS in resource-constrained settings: informing urgent policy changes. Lancet. 2007;369(9578):2042–2049. doi:10.1016/S0140-6736(07)60284-0.
  • Rasoahanitralisoa R, Rakotosamimanana N, Stucki D, Sola C, Gagneux S, Rasolofo Razanamparany V. Evaluation of spoligotyping, SNPs and customised MIRU-VNTR combination for genotyping Mycobacterium tuberculosis clinical isolates in Madagascar. PLoS One. 2017;12(10):e0186088. doi:10.1371/journal.pone.0186088.
  • Gazi MA, Islam MR, Kibria MG, Mahmud Z. General and advanced diagnostic tools to detect Mycobacterium tuberculosis and their drug susceptibility: A review. Eur J Clin Microbiol Infect Dis. 2015;34(5):851–861. doi:10.1007/s10096-014-2306-5.
  • Gori A, Bandera A, Marchetti G, et al. Spoligotyping Mycobacterium tuberculosis. Emerg Infect Dis. 2005;11(8):1242–1248.
  • Drobniewski F, Nikolayevskyy V, Maxeiner H, et al. Rapid diagnostics of tuberculosis and drug resistance in the industrialized world: clinical and public health benefits and barriers to implementation. BMC Med. 2013;11(1):190. doi:10.1186/1741-7015-11-190.
  • Nathavitharana RR, Cudahy PGT, Schumacher SG, Steingart KR, Pai M, Denkinger CM. Accuracy of line probe assays for the diagnosis of pulmonary and multidrug-resistant tuberculosis: a systematic review and meta-analysis. Eur Respir J. 2017;49(1): pii:1601075. http://erj.ersjournals.com/content/49/1/1601075.abstract.
  • Wilson ML. Rapid diagnosis of Mycobacterium tuberculosis Infection and Drug Susceptibility Testing. Arch Pathol Lab Med. 2013;137(6):812–819. doi:10.5858/arpa.2011-0578-RA.
  • Singh BK, Sharma SK, Sharma R, et al. Diagnostic utility of a line probe assay for multidrug resistant-TB in smear-negative pulmonary tuberculosis. PLoS One. 2017;12(8):e0182988. doi:10.1371/journal.pone.0182988.
  • Gondil VS, Chhibber S. Exploring potential of phage therapy for tuberculosis using model organism. Biomed Biotechnol Res J. 2018;2(9):9–15. doi:10.4103/bbrj.bbrj.
  • Rishi E, Rishi P, Therese KL, et al. Culture and Reverse Transcriptase Polymerase Chain Reaction (RT-PCR) proven mycobacterium tuberculosis endophthalmitis: A case series. Ocul Immunol Inflamm. 2018;26(2):220–227. doi:10.1080/09273948.2016.1207786.
  • Bento J, Silva A, Rodrigues F, Duarte R. Diagnostic tools in tuberculosis. Acta Med Port. 2011;24(1):145–154.
  • Blakemore R, Story E, Helb D, et al. Evaluation of the analytical performance of the Xpert MTB/RIF assay. J Clin Microbiol. 2010;48(7):2495–2501. doi:10.1128/JCM.00128-10.
  • Munir MK, Rehman S, Iqbal R, Saeed MS. Comparison of gene Xpert MTB/RIF assays with conventional standard proportion method for determination of drug susceptibility in multidrug resistant TB suspects. Annals of King Edward Medical University. 2018;24(1):86–92.
  • Nhu NTQ, Heemskerk D, Thu DDA, et al. Evaluation of GeneXpert MTB/RIF for diagnosis of tuberculous meningitis. Carroll KC, ed. J Clin Microbiol. 2014;52(1):226–233. doi:10.1128/JCM.01834-13.
  • Chakravorty S, Simmons AM, Rowneki M, et al. The new Xpert MTB/RIF ultra: improving detection of Mycobacterium tuberculosis and resistance to rifampin in an assay suitable for point-of-care testing. mBio 2017;8(4):e00812–e00817. doi:10.1128/mBio.00812-17.
  • Kasa Tom S, Welch H, Kilalang C, et al. Evaluation of Xpert MTB/RIF assay in children with presumed pulmonary tuberculosis in Papua New Guinea. Paediatr Int Child Health. 2018;38(2):97–105. doi:10.1080/20469047.2017.1319898.
  • Lima TM de, Belotti NCU, Nardi SMT, Pedro H da SP. Teste rápido molecular GeneXpert MTB/RIF para diagnóstico da tuberculose. Rev Pan-Amazônica Saúde. 2017;8(2):65–76. doi:10.5123/S2176-62232017000200008.
  • Nikam C, Jagannath M, Narayanan MM, et al. Rapid diagnosis of Mycobacterium tuberculosis with Truenat MTB: A Near-Care Approach. Neyrolles O, ed. PLoS One. 2013;8(1):e51121. doi:10.1371/journal.pone.0051121.
  • Nikam C, Kazi M, Nair C, et al. Evaluation of the Indian TrueNAT micro RT-PCR device with GeneXpert for case detection of pulmonary tuberculosis. Int J Mycobacteriology. 2014;3(3):205–210. doi:10.1016/j.ijmyco.2014.04.003.
  • Baron EJ, Tenover FC, Gnanashanmugam D. Direct detection of mycobacterium tuberculosis in clinical specimens using nucleic acid amplification tests. Clin Microbiol Newsl. 2018;40(13):107–112. doi:10.1016/j.clinmicnews.2018.06.003.
  • Augusto CJ, Carvalho W da S, Almeida IN de, et al. Comparative study of RFLP-IS6110 and MIRU-VNTR from Mycobacterium tuberculosis isolated in the state of Minas Gerais, Brazil. Brazilian J Microbiol. 2018;49(3):641–646. doi:10.1016/j.bjm.2017.04.015.
  • Khan AS, Ali S, Khan MT, et al. Comparison of GeneXpert MTB/RIF assay and LED-FM microscopy for the diagnosis of extra pulmonary tuberculosis in Khyber Pakhtunkhwa, Pakistan. Brazilian J Microbiol. 2018;49(4):909–913. doi:10.1016/j.bjm.2018.02.011.
  • Daum LT, Konstantynovska OS, Solodiankin OS, et al. Next-generation sequencing for characterizing drug resistant mycobacterium tuberculosis genes from clinical isolates in the Ukraine. J Clin Microbiol. 2018;56(6). doi:10.1128/JCM.00009-18.
  • Ma G, Pan J, Han J, Gao L, Zhang S, Li R. Identification of M. tuberculosis antigens in the sera of tuberculosis patients using biomimetic affinity chromatography in conjunction with ESI-CID-MS/MS. J Chromatogr B. 2017;1061–1062:452–458. doi:10.1016/j.jchromb.2017.07.052.
  • Shah J, Weltman H, Narciso P, et al. Dual color fluorescence in situ hybridization (FISH) assays for detecting Mycobacterium tuberculosis and Mycobacterium avium complexes and related pathogens in cultures. PLoS One. 2017;12(4):e0174989. doi:10.1371/journal.pone.0174989.
  • Neonakis IK, Spandidos DA, Petinaki E. Use of loop-mediated isothermal amplification of DNA for the rapid detection of Mycobacterium tuberculosis in clinical specimens. Eur J Clin Microbiol Infect Dis. 2011;30(8):937–942. doi:10.1007/s10096-011-1195-0.
  • Haas CT, Roe JK, Pollara G, Mehta M, Noursadeghi M. Diagnostic ‘omics’ for active tuberculosis. BMC Med. 2016;14(1):37. doi:10.1186/s12916-016-0583-9.
  • Matkar S, Mukundan U. MALDI-TOF MS for rapid identification of Mycobacterium species in liquid culture media. J Bacteriol Mycol. 2018;6(2):105–107. doi:10.15406/jbmoa.2018.06.00185.
  • Patel R. MALDI-TOF MS for the diagnosis of infectious diseases. Clin Chem. 2015;61(1): LP100–111. http://clinchem.aaccjnls.org/content/61/1/100.abstract.
  • Santos T, Capelo JL, Santos HM, et al. Use of MALDI-TOF mass spectrometry fingerprinting to characterize Enterococcus spp. and Escherichia coli isolates. J Proteomics. 2015;127:321–331. doi:10.1016/j.jprot.2015.02.017.
  • Sun H, Pan L, Jia H, et al. Label-free quantitative proteomics identifies novel plasma biomarkers for distinguishing pulmonary tuberculosis and latent infection. Front Microbiol. 2018;9:1267. doi:10.3389/fmicb.2018.01267.
  • Agranoff D, Fernandez-Reyes D, Papadopoulos MC, et al. Identification of diagnostic markers for tuberculosis by proteomic fingerprinting of serum. Lancet. 2006;368(9540):1012–1021. doi:10.1016/S0140-6736(06)69342-2.
  • Wang C, Wei L-L, Shi L-Y, et al. Screening and identification of five serum proteins as novel potential biomarkers for cured pulmonary tuberculosis. Sci Rep. 2015;5:15615. doi:10.1038/srep15615.
  • Duncan C, Jamieson FB, Troudt J, et al. Whole transcriptomic and proteomic analyses of an isogenic M. tuberculosis clinical strain with a naturally occurring 15 Kb genomic deletion. PLoS One. 2017;12(6):e0179996. doi:10.1371/journal.pone.0179996.
  • Achkar JM, Cortes L, Croteau P, et al. Host protein biomarkers identify active tuberculosis in HIV uninfected and co-infected individuals. EBioMed. 2015;2(9):1160–1168. doi:10.1016/j.ebiom.2015.07.039.
  • Berry MPR, Graham CM, McNab FW, et al. An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis. Nature. 2010;466:973. doi:10.1038/nature09247.
  • Mejias A, Suarez NM, Ramilo O. Detecting specific infections in children through host responses: A Paradigm Shift. Curr Opin Infect Dis. 2014;27(3):228–235. doi:10.1097/QCO.0000000000000065.
  • Weiner J, Parida SK, Maertzdorf J, et al. Biomarkers of inflammation, immunosuppression and stress are revealed by metabolomic profiling of tuberculosis patients. Wilkinson RJ, ed. PLoS One. 2012;7(7):e40221. doi:10.1371/journal.pone.0040221.
  • Lau SKP, Lee K-C, Curreem SOT, et al. Metabolomic profiling of plasma from patients with tuberculosis by use of untargeted mass spectrometry reveals novel biomarkers for diagnosis. Land GA, ed. J Clin Microbiol. 2015;53(12):3750–3759. doi:10.1128/JCM.01568-15.
  • Ahmad S, Mokaddas E. Current status and future trends in the diagnosis and treatment of drug-susceptible and multidrug-resistant tuberculosis. J Infect Public Health. 2014;7(2):75–91. doi:10.1016/j.jiph.2013.09.001.
  • Cudahy P, Shenoi S. Diagnostics for pulmonary tuberculosis. Postgrad Med J. 2016;92(1086):187–193. doi:10.1136/postgradmedj-2015-133278.
  • Hertting O, Shingadia D. Childhood TB: When to think of it and what to do when you do. J Infect. 2014;68:S151–S154. doi:10.1016/j.jinf.2013.09.025.
  • Heemskerk D, Caws M, Marais B, Farrar J. Tuberculosis in Adults and Children. London: Springer; 2015.

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