Effects of irradiation in the mandibular bone loaded with dental implants. An experimental study with a canine model

References

• Brennan MT, Elting LS, Spijkervet FK. Systematic reviews of oral complications from cancer therapies. Oral Care Study Group, MASCC/ISOO; methodology and quality of the literature. Support Care Cancer. 2010;18(8):979–984. doi:https://doi.org/10.1007/s00520-010-0856-3.
   PubMed Web of Science ®Google Scholar
• Alsaadi G, Quirynen M, Komárek A, van Steenberghe D. Impact of local and systemic factors on the incidence of late oral implant loss. Clin Oral Implants Res. 2008;19:670–676.
   PubMed Web of Science ®Google Scholar
• Guise T. Bone loss and fracture risk associated with cancer therapy. Oncologist. 2006;11(10):1121–1131. doi:https://doi.org/10.1634/theoncologist.11-10-1121.
   PubMed Web of Science ®Google Scholar
• Brasseur M, Brogniez V, Grêgoire V, et al. Effects of irradiation on bone remodelling around mandibular implants: an experimental study on gogs. Int J Oral Maxillofac Surg. 2006;35(9):850–855. doi:https://doi.org/10.1016/j.ijom.2006.03.016.
   PubMed Web of Science ®Google Scholar
• Jegoux F, Malard O, Goyenvalle E, Aguado E, Daculsi G. Radiation effects on bone healing and reconstruction: interpretation of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endodontol. 2010;109(2):173–184.doi:https://doi.org/10.1016/j.tripleo.2009.10.001.
   PubMed Web of Science ®Google Scholar
• Friberg B, Jemt T, Lekholm U. Early failures in 4,641 consecutively placed Branemark dental implants: a study from stage 1 surgery to the connection of completed prostheses. Int J Oral Maxillofac Implants. 1991;6:142–146.
   PubMedGoogle Scholar
• Salonen MA, Oikarinen K, Virtanen K, Pernu H. Failures in the osseointegration of endosseous implants. Int J Oral Maxillofac Implants. 1993;8:92–97.
   PubMedGoogle Scholar
• Listgarten MA. Soft and hard tissue response to endosseous dental implants. Anat Rec. 1996;245(2):410–425. doi:https://doi.org/10.1002/(SICI)1097-0185(199606)245:2<410::AID-AR20>3.0.CO;2-R.
   PubMedGoogle Scholar
• Marco F, Milena F, Gianluca G, Vittoria O. Peri-implant osteogenesis in health and osteoporosis. Micron. 2005;36(7–8):630–644. doi:https://doi.org/10.1016/j.micron.2005.07.008.
   PubMed Web of Science ®Google Scholar
• Berglundh T, Abrahamsson I, Lang NP, Lindhe J. De novo alveolar bone formation adjacent to endosseous implants. Clin Oral Implants Res. 2003;14(3):251–262. doi:https://doi.org/10.1034/j.1600-0501.2003.00972.x.
   PubMed Web of Science ®Google Scholar
• Abrahamsson I, Berglundh T, Linder E, Lang NP, Lindhe J. Early bone formation adjacent to rough and turned endosseous implant surfaces. An experimental study in the dog. Clin Oral Implants Res. 2004;15(4):381–392. doi:https://doi.org/10.1111/j.1600-0501.2004.01082.x.
   PubMed Web of Science ®Google Scholar
• Verdonck HW, Meijer GJ, Nieman FH, Stoll C, Riediger D, de Baat C. Quantitative computed tomography bone mineral density measurements in irradiated and non-irradiated minipig alveolar bone: an experimental study. Clin Oral Implants Res. 2008;19(5):465–468. doi:https://doi.org/10.1111/j.1600-0501.2007.01496.x.
   PubMed Web of Science ®Google Scholar
• Mendes EM, Irie MS, Rabelo GD, et al. Effects of ionizing radiation on woven bone: influence on the osteocyte lacunar network, collagen maturation, and microarchitecture. Clin Oral Investig. 2020;24(8):2763–2771. doi:https://doi.org/10.1007/s00784-019-03138-x.
   PubMed Web of Science ®Google Scholar
• Schön R, Ohno K, Kudo M, Michi KI. Peri-implant tissue reaction in bone irradiated the fifth day after implantation in rabbits: histologic and histomorphometric measurements. Int J Oral Maxillofac Implants. 1996;11:228–238.
   PubMedGoogle Scholar
• Kudo M, Matsui Y, Ohno K, Michi KI. A histomorphometric study of the tissue reaction around hydroxyapatite implants irradiated after placement. J Oral Maxillofac Surg. 2001;59(3):293–300. doi:https://doi.org/10.1053/joms.2001.20998.
   PubMed Web of Science ®Google Scholar
• Brogniez V, Nyssen-Behets C, Gre´-goire V, Reychler H, Lengele´ B. Implant osseointegration in the irradiated mandible. A comparative study in dogs with a microradiographic and histologic assessment. Clin Oral Implants Res. 2002;13(3):234–242. doi:https://doi.org/10.1034/j.1600-0501.2002.130302.x.
   PubMed Web of Science ®Google Scholar
• Nogueira LP, Braz D, Barroso RC, et al. 3D histomorphometric quantification of trabecular bones by computed microtomography using synchrotron radiation. Micron. 2010;41(8):990–996. doi:https://doi.org/10.1016/j.micron.2010.06.013.
   PubMed Web of Science ®Google Scholar
• Asikainen P, Klemetti E, Kotilainen R, et al. Osseointegration of dental implants in bone irradiated with 40, 50 or 60 Gy doses. An experimental study with beagle dogs. Clin Oral Implants Res. 1998;9(1):20–25. doi:https://doi.org/10.1034/j.1600-0501.1998.090103.x.
   PubMed Web of Science ®Google Scholar
• Burr DB, Stafford T. Validity of the bulk-staining technique to separate artifactual from in vivo bone microdamage. Clin Orthop Relat Res. 1990;260:305–308. doi:https://doi.org/10.1097/00003086-199011000-00047.
   PubMed Web of Science ®Google Scholar
• Heinonen V, Routsalainen TJ, Paavola L, et al. Alveolar bone remodelling after tooth extraction in irradiated mandible: an experimental study with canine model. Ultrastruct Pathol. 2018;42(2):124–132. doi:https://doi.org/10.1080/01913123.2017.1422829.
   PubMed Web of Science ®Google Scholar
• de Faria Vasconcelos K, Dos Santos Corpas L, da Silveira BM, et al. MicroCT assessment of bone microarchitecture in implant sites reconstructed with autogenous and xenogenous grafts: a pilot study. Clin Oral Implants Res. 2017;28(3):308–313. doi:https://doi.org/10.1111/clr.12799.
   PubMed Web of Science ®Google Scholar
• Feng JQ, Ward LM, Liu S, et al. Loss of DMP1 causes rickets and osteomalacia and identifies the role for osteocytes in mineral metabolism. Nat Genet. 2006;38(11):1310–1315. doi:https://doi.org/10.1038/ng1905.
   PubMed Web of Science ®Google Scholar
• Kubek DJ, GattoneII VH, Allen MR. Methodological assessment of acid-etching for visualizing the osteocyte lacunar-canalicular networks using scanning electron microscopy. Microsc Res Tech. 2010;73:182–186.
   PubMed Web of Science ®Google Scholar
• Lampi T, Dekker H, Ten Bruggenkate CM, et al. Acid-etching technique of non-decalcified bone samples for visualizing osteocyte-lacuno-canalicular network using scanning electron microscope. Ultrastruct Pathol. 2018;42(1):74–79. doi:https://doi.org/10.1080/01913123.2017.1384418.
   PubMed Web of Science ®Google Scholar
• Burr DB, Allen MR. Mandibular necrosis in beagle dogs treated with bisphosphonates. Orthod Craniofac Res. 2009;12(3):221–228. doi:https://doi.org/10.1111/j.1601-6343.2009.01456.x.
   PubMed Web of Science ®Google Scholar
• Allen MR, Burr DB. Mandible matrix necrosis in beagle dogs after 3 years of daily oral bisphosphonate treatment. J Oral Maxillofac Surg. 2008;66(5):987–994. doi:https://doi.org/10.1016/j.joms.2008.01.038.
   PubMed Web of Science ®Google Scholar
• Huja SS, Fernandez SA, Hill KJ, Li Y. Remodeling dynamics in the alveolar process in skeletally mature dogs. Anat Rec A Discov Mol Cell Evol Biol.  2006;288(12):1243-1249. doi:https://doi.org/10.1002/ar.a.20396.
   Google Scholar
• Visch LL, Van Waas MAJ, Schmitz PIM, Levendag PC. A clinical evaluation of implants in irradiated oral cancer patients. J Dent Res. 2002;81(12):856–859. doi:https://doi.org/10.1177/154405910208101212.
   PubMed Web of Science ®Google Scholar
• Cole HA, Ohba T, Ichikawa J, et al. Micro-computed tomography derived anisotropy detects tumor provoked deviations in bone in an orthotopic osteosarcoma murine model. PLoS One. Jun 3 2014;9(6):e97381. doi:https://doi.org/10.1371/journal.pone.0097381.
   PubMed Web of Science ®Google Scholar
• Dong P, Haupert S, Hesse B, et al. 3D osteocyte lacunar morphometric properties and distributions in human femoral cortical bone using synchrotron radiation micro-CT images. Bone. Mar 2014;60:172–185. doi:https://doi.org/10.1016/j.bone.2013.12.008.
   PubMed Web of Science ®Google Scholar
• Lian Z, Guan H, Ivanovski S, Loo YC, Johnson NW, Zhang H. Effect of bone to implant contact percentage on bone remodelling surrounding a dental implant. Int J Oral Maxillofac Surg. 2010;39(7):690–698. doi:https://doi.org/10.1016/j.ijom.2010.03.020.
   PubMed Web of Science ®Google Scholar
• Park YS, Yi KY, Lee IS, Jung YC. Correlation between microtomography and histomorphometry for assessment of implant osteointegration. Clin Oral Implants Res. 2005;16:156–160. doi:https://doi.org/10.1111/j.1600-0501.2004.01083.x.
   PubMed Web of Science ®Google Scholar
• Haga M, Nozawa-Inoue K, Li M, Oda K, Maeda T, Morphological A. Analysis on the osteocytic lacunar canalicular system in bone surrounding dental implants. Oral Biol. 2011;294(6):1074–1082.
   Google Scholar
• Takahashi S, Sugimoto M, Kotoura Y, Sasai K, Oka M, Yamamuro T. Long-term changes in the Harversian systems following high – dose irradiation. an ultrastructural and quantitative histomorphology study. J Bone Joint Surg. 1994;76(5):722–738.doi:https://doi.org/10.2106/00004623-199405000-00014.
   PubMed Web of Science ®Google Scholar
• Dekker H, Bravenboer N, Dijk DV, et al. The irradiated human mandible: a quantitative study on bone vascularity. Oral Oncol. 2018;87:126–130. doi:https://doi.org/10.1016/j.oraloncology.2018.10.030.
   PubMed Web of Science ®Google Scholar