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Basic Research

Could vitamin D protect against high fat diet induced damage in the arcuate nucleus in the rat: histological, immunohistochemical and ultrastructural study

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Pages 292-303 | Received 13 Jan 2023, Accepted 22 Mar 2023, Published online: 29 Mar 2023

References

  • Xu L, Li D, Li H, et al. Suppression of obesity by melatonin through increasing energy expenditure and accelerating lipolysis in mice fed a high-fat diet. Nutrition & Diabetes. 2022;12(1):1–12. doi:10.1038/s41387-022-00222-2.
  • Rees A, Richards O, ALLEN-KORMYLO A, Jones N, Thornton CA. Maternal body mass index is associated with an altered immunological profile at 28 weeks of gestation. Clin Exp Immunol. 2022;208(1):114–128. doi:10.1093/cei/uxac023.
  • Blüher M. Obesity: global epidemiology and pathogenesis. Nat Rev Endocrinol. 2019;15(5):288–298. doi:10.1038/s41574-019-0176-8.
  • Naureen I, Saleem A, Naeem M, et al. Effect of exercise and obesity on human physiology. Sch Bull. 2022;8(1):17–24. doi:10.36348/sb.2022.v08i01.003.
  • Pamuk F, Kantarci A. Inflammation as a link between periodontal disease and obesity. Periodontology 2000. 2022;90(1):186–196. doi:10.1111/prd.12457.
  • Sheikh MH, Errede M, D’amati A, et al. Impact of metabolic disorders on the structural, functional, and immunological integrity of the blood‐brain barrier: therapeutic avenues. Faseb J. 2022;36(1):e22107. doi:10.1096/fj.202101297R.
  • Acosta A. Control of Food Intakepp. 478–486. John Wiliy & Sons Ldt.: Yamada’s Textbook of Gastroenterology; 2022.
  • Polzonetti V, Pucciarelli S, Vincenzetti S, Polidori P. Dietary intake of vitamin d from dairy products reduces the risk of osteoporosis. Nutrients. 2020;12(6):1743. doi:10.3390/nu12061743.
  • Barvencik F, Amling M. Vitamin D metabolism of the bone. Der Orthopade. 2015;44(9):686–694. doi:10.1007/s00132-015-3135-7.
  • Holick MF. The vitamin D deficiency pandemic: approaches for diagnosis, treatment and prevention. Rev Endocr Metab Disord. 2017;18(2):153–165. doi:10.1007/s11154-017-9424-1.
  • Christakos S, Hewison M, Gardner DG, et al. Vitamin D: beyond bone. Ann N Y Acad Sci. 2013;1287(1):45–58. doi:10.1111/nyas.12129.
  • Vimaleswaran KS, Berry DJ, Lu C, et al. Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts. PLoS Med. 2013;10(2):e1001383. doi:10.1371/journal.pmed.1001383.
  • Sadek KM, Shaheen H. Biochemical efficacy of vitamin D in ameliorating endocrine and metabolic disorders in diabetic rats. Pharm Biol. 2014;52(5):591–596. doi:10.3109/13880209.2013.854812.
  • Gomaa AM, Abd El-Aziz EA. Vitamin D reduces high-fat diet induced weight gain and C-reactive protein, increases interleukin-10, and reduces CD86 and caspase-3. Pathophysiology. 2017;24(1):31–37. doi:10.1016/j.pathophys.2017.01.003.
  • Snyder JM, Radaelli E, Goeken A, et al. Perfusion with 10% neutral-buffered formalin is equivalent to 4% paraformaldehyde for histopathology and immunohistochemistry in a mouse model of experimental autoimmune encephalomyelitis. Vet Pathol. 2022;59(3):03009858221075588. doi:10.1177/03009858221075588.
  • Bancroft JD, Gamble M. Theory and Practice of Histological Techniques. Oxford: Churchill livingstone.: Elsevier health sciences; 2008.
  • Wyffels JT. Principles and techniques of electron microscopy: biological applications, by MA Hayat. Microscopy and Microanalysis. 2001;7:0066.
  • Aravindraja C, Sakthivel R, Liu X, et al. Intracerebral but not peripheral infection of live porphyromonas gingivalis exacerbates alzheimer’s disease like amyloid pathology in APP-Tgcrnd8 Mice. Int J Mol Sci. 2022;23(6):3328. doi:10.3390/ijms23063328.
  • Connelly LM. Introduction to analysis of variance (ANOVA). Medsurg Nursing. 2021;30:158–218.
  • Cavaliere G, Viggiano E, Trinchese G, et al., Long feeding high-fat diet induces hypothalamic oxidative stress and inflammation, and prolonged hypothalamic AMPK activation in rat animal model. Front Physiol. 2018;9:818. doi:10.3389/fphys.2018.00818.
  • Kim JD, Ryu S-Y, Yun I, et al. Microglial UCP2 mediates inflammation and obesity induced by high-fat feeding. Cell Metab. 2019;30(5):952–962. e5. doi:10.1016/j.cmet.2019.08.010.
  • Sengupta P. The laboratory rat: relating its age with human’s. Int J Prev Med. 2013;4:624.
  • Moraes JC, Coope A, Morari J, et al. High-fat diet induces apoptosis of hypothalamic neurons. PLoS One. 2009;4(4):e5045. doi:10.1371/journal.pone.0005045.
  • Engin A. Diet-induced obesity and the mechanism of leptin resistance. Obesity and Lipotoxicity . 2017;960:381–397.
  • Preninka AI, Kuriya K, Yazawa K, et al. Homocysteine causes neuronal leptin resistance and endoplasmic reticulum stress. PLoS One. 2022;17(12):e0278965. doi:10.1371/journal.pone.0278965.
  • Hou J, Jeon B, Baek J, et al. High fat diet-induced brain damaging effects through autophagy-mediated senescence, inflammation and apoptosis mitigated by ginsenoside F1-enhanced mixture. J Ginseng Res. 2022;46(1):79–90. doi:10.1016/j.jgr.2021.04.002.
  • Huang H-T, Tsai S-F, Wu H-T, et al. Chronic exposure to high fat diet triggers myelin disruption and interleukin-33 upregulation in hypothalamus. BMC Neurosci. 2019;20(1):1–11. doi:10.1186/s12868-019-0516-6.
  • Wang C, Zhang H, Fan J, et al. Inhibition of integrated stress response protects against lipid-induced senescence in hypothalamic neural stem cells in adamantinomatous craniopharyngioma. Neuro Oncol. 2022. doi:10.1093/neuonc/noac261.
  • Debette S, Wolf C, Lambert J-C, et al. Abdominal obesity and lower gray matter volume: a Mendelian randomization study. Neurobiol Aging. 2014;35(2):378–386. doi:10.1016/j.neurobiolaging.2013.07.022.
  • Namavar MR, Raminfard S, Jahromi ZV, Azari H. Effects of high-fat diet on the numerical density and number of neuronal cells and the volume of the mouse hypothalamus: a stereological study. Anatomy & Cell Biology. 2012;45(3):178–184. doi:10.5115/acb.2012.45.3.178.
  • Annweiler C. Vitamin D in dementia prevention. Ann N Y Acad Sci. 2016;1367(1):57–63. doi:10.1111/nyas.13058.
  • Nameni G, Hajiluian G, Shahabi P, et al. The impact of vitamin D supplementation on neurodegeneration, TNF-α concentration in hypothalamus, and CSF-to-plasma ratio of insulin in high-fat-diet-induced obese rats. J Mol Neurosci. 2017;61(2):247–255. doi:10.1007/s12031-016-0864-y.
  • Kim J-S, Yoon NA, Jin S, et al. 1α,25-Dihydroxyvitamin D3 protects dopaminergic neurons in rodent models of parkinson’s disease through inhibition of microglial activation. J Clin Neurol. 2006;2(4):252–257. doi:10.3988/jcn.2006.2.4.252.
  • Brown J, Bianco JI, Mcgrath JJ, Eyles DW. 1, 25-dihydroxyvitamin D3 induces nerve growth factor, promotes neurite outgrowth and inhibits mitosis in embryonic rat hippocampal neurons. Neurosci Lett. 2003;343(2):139–143. doi:10.1016/S0304-3940(03)00303-3.
  • Selhorst A. The Neuroprotective Role of Vitamin D on Neurons in a Central Nervous System Autoimmune Disease. The Ohio State University. Biological Sciences Honors Theses; 2015.

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