Advanced search
Publication Cover
Ultrastructural Pathology Volume 23, 1999 - Issue 5
Submit an article Journal homepage
21
Views
6
CrossRef citations to date
0
Altmetric
Research Article

Crystalloid Inclusions in Brain Macrophages and Hemopoietic Tissue in GFAP-IL3 Mice Resemble Inclusions Identified in Multiple Sclerosis

Henry C. Powell, Robert S. Garrett, Atis Muehlenbachs, Francesca M. Brett, Iain L. Campbell Department of Pathology,University of California at San Diego,La Jolla, California, USA; Department of Neuropharmacology,The Scripps Research Institute,La Jolla, California, USA
Pages 285-297 | Published online: 10 Jul 2009

References

  • Bessis M, Weed RI, trans. Living Blood Cells and Their Ultrastructure. New York: Springer; 1973.
  • Hudson G. Crystalloid material in macrophages of mouse bone marrow. Acta Anat. 1968; 71: 100–107.
  • Shaklai M, Tavassoloni M. Crystalloid inclusions in mouse macrophage [letter]. Lancet. 1977; 2(8032), 305.
  • Marshall GE, Shortland JR, Hudson G. Crystalloid material in cells of the murine mononuclear phagocyte system. J Anat. 1988; 157: 217–228.
  • Carr I, Norris P. The fine structure of human macrophage granules in sarcoidosis. J Pathol. 1977; 122: 29–32.
  • Rodriguez M, Scheithauer B. Ultrastructure of multiple sclerosis. Ultrastruct Pathol. 1994; 18: 3–13.
  • Molnar M, Schroder JM. Pleomorphic mitochondrial and different filamentous inclusions in inflammatory neuropathies associated with mtDNA deletions. Acta Neuropathol. 1998; 96: 41–51.
  • Ali BA, Shortland JR, Hudson G. Origin of crystalloid inclusions in macrophages, 1: studies of peritoneal macrophages after erythrocyte ingestion. Br J Exp Pathol. 1981; 62: 655–661.
  • Komuves LG, Nicols BL, Hutchens TW, Heath JP. Formation of crystalloid inclusions in the small intestine of neonatal pigs: an immunocytochemical study using colloidal gold. Histochemistry. 1993; 25: 19–29.
  • LeGall IM, Bendayan M. Possible association of chaperonin 60 with secretory proteins in pancreatic acinar cells. J Histochem Cytochem. 1996; 44: 743–749.
  • Chiang CS, Powell HC, Gold LH, Samimi A, Campbell IL. Macrophage/microglial-mediated primary demyelination and motor disease induced by the central nervous system production of interleukin-3 in transgenic mice. J Clin Invest. 1996; 97: 1512–1524.
  • Campbell IL, Powell HC. Role of cytokines in demyelination. Methods Enzymol. 1996; 10: 462–477.
  • Yamazaki K. Isolated cilia and crystalloid inclusions in murine bone marrow stromal cells. Blood Cells. 1988; 13: 407–419.
  • Powell HC, Garrett RS, Brett FM, et al. Response of glia, mast cells and the blood brain barrier, in transgenic mice expressing interleukin-3 in astrocytes, an experimental model for CNS demyelination. Brain Pathol. 1999; 9: 219–235.
  • Arias AE, Velez-Granell CS, Torres-Ruiz JA, Bendayan M. Involvement of molecular chaperones in the abberant aggregation of secretory proteins in pancreatic acinar cells. Exp Cell Res. 1994; 215: 1–8.
  • Murray AB, Luz A. Acidophilic macrophage pneumonia in laboratory mice. Vet Pathol. 1990; 27: 274–281.
  • Lira SA, Zalamea P, Heinrich JN, et al. Expression of the chemokine N51/KC in the thymus and epidermis of transgenic mice results in marked infiltration of a single class of inflammatory cells. J Exp Med. 1994; 180: 2039–2048.
  • Roels F, Espeel M, Poggi F, Mandel H, van Maldergem L, Saudubray JM. Human liver pathology in peroxisomal diseases: a review including novel data. Biochimie. 1993; 75: 281–292.
  • Renaut, J. Les cellules connectives rhagiocrines. Arch Anat Microsc. 1907; 9: 495–606.
  • Arias AE, Bendayan M. Intracisternal crystals in pancreatic acinar cells: failure in the distinct aggregation of acinar proteins. Eur Cell Biol. 1993; 62: 282–293.
  • Ellis RJ, Hartl FU. Protein folding in the cell: competing models of chaperonin function. FASEB J. 1996; 10: 20–26.
  • Welch WJ, Gambetti P. Chaperoning brain diseases. Nature. 1998;392(6671):23–24.
  • Mott FW. Observations on the brain of men and animals infected with trypanosomes: preliminary note. Proc R Soc Lond. 1905; 76: 235–242.
  • White RG. Observations on the formation and nature of Russell bodies. Br J Exp Pathol. 1954; 35: 365–376.
  • Brown WR, Hardy MH. A hypothesis on the cause of chronic epidermal hyperproliferation in asebia mice. Clin Exp Dermatol. 1988; 13: 74–77.
  • Klinkner AM, Waites CR, Kerns WD, Bugelski PJ. Evidence of foam cell and cholesterol crystal formation in macrophages incubated with oxidized LDL by fluorescence and electron microscopy. J Histochem Cytochem. 1995; 43: 1071–1078.
  • Ward JM. Pulmonary pathology of the motheaten mouse. Vet Pathol. 1978; 15: 170–178.
  • Ranga V, Kleinerman J. Lung injury and repair in the blotchy mouse: effects of nitrogen dioxide inhalation. Annu Rev Respir Dis. 1981; 123: 90–97.
  • de Santi MM, Martorana PA, Cavarra E, Lungarella G. Pallid mice with genetic emphysema: neutrophil elastase burden and elastin loss occur without alteration in the bronchoalveolar lavage cell population. Lab Invest. 1995; 73: 40–47.
  • Simons JF, Ferro-Novick S, Rose MD, Helenius A. BiP/ Kar 2p serves as a molecular chaperone during carboxypeptidase Y folding in yeast. J Cell Biol. 1995; 130: 41–49.
  • Prabakhar S, Kurien E, Gupta RS, Zielinski S, Freedman MS. Heat shock protein, immunoreactivity in CSF: correlation with oligoclonal banding and demyelinating disease. Neurology. 1994; 44: 1644–1648.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.