References
- Al’Absi, M., & Petersen, K. L. (2003). Blood pressure but not cortisol mediates stress effects on subsequent pain perception in healthy men and women. Pain, 106(3), 285–295. https://doi.org/https://doi.org/10.1016/S0304-3959(03)00300-2
- Badrov, M. B., Horton, S., Millar, P. J., & Mcgowan, C. L. (2013). Cardiovascular stress reactivity tasks successfully predict the hypotensive response of isometric handgrip training in hypertensives. Psychophysiology, 50(4), 407–414. https://doi.org/https://doi.org/10.1111/psyp.12031
- Bland, J. M., & Altman, D. G. (1995). Statistics notes: Calculating correlation coefficients with repeated observations: Part 1—correlation within subjects. Bmj, 310(6977), 446. https://doi.org/https://doi.org/10.1136/bmj.310.6977.446
- Bossut, D. F., & Maixner, W. (1996). Effects of cardiac vagal afferent electrostimulation on the responses of trigeminal and trigeminothalamic neurons to noxious orofacial stimulation. Pain, 65(1), 101–109. https://doi.org/https://doi.org/10.1016/0304-3959(95)00166-2
- Cahu Rodrigues, S. L., Farah, B. Q., Silva, G., Correia, M., Pedrosa, R., Vianna, L., & Ritti-Dias, R. M. (2020). Vascular effects of isometric handgrip training in hypertensives. Clinical and Experimental Hypertension, 42(1), 24–30. https://doi.org/https://doi.org/10.1080/10641963.2018.1557683
- Cayot, T. E., Lauver, J. D., Silette, C. R., & Scheuermann, B. W. (2016). Effects of blood flow restriction duration on muscle activation and microvascular oxygenation during low-volume isometric exercise. Clinical Physiology and Functional Imaging, 36(4), 298–305. https://doi.org/https://doi.org/10.1111/cpf.12228
- Chesterton, L. S., Barlas, P., Foster, N. E., Baxter, G. D., & Wright, C. C. (2003). Gender differences in pressure pain threshold in healthy humans. Pain, 101(3), 259–266. https://doi.org/https://doi.org/10.1016/S0304-3959(02)00330-5
- Copithorne, D. B., & Rice, C. L. (2019). The effect of blood flow occlusion during acute low-intensity isometric elbow flexion exercise. European Journal of Applied Physiology, 119(3), 587–595. https://doi.org/https://doi.org/10.1007/s00421-019-04088-8
- Crombie, K. M., Brellenthin, A. G., Hillard, C. J., & Koltyn, K. F. (2018). Endocannabinoid and opioid system interactions in exercise-induced hypoalgesia. Pain Medicine, 19(1), 118–123. https://doi.org/https://doi.org/10.1093/pm/pnx058
- D’Antono, B., Ditto, B., Sita, A., & Miller, S. B. (2000). Cardiopulmonary baroreflex stimulation and blood pressure-related hypoalgesia. Biological Psychology, 53(2–3), 217–231. https://doi.org/https://doi.org/10.1016/S0301-0511(00)00044-2
- Drury, D. G., Stuempfle, K., Shannon, R., & Miller, J. (2004). An investigation of exercise-induced hypoalgesia after isometric and cardiovascular exercise. Journal of Exercise Physiology, 7(4), 1–5.
- Ellingson, L. D., Koltyn, K. F., Kim, J. S., & Cook, D. B. (2014). Does exercise induce hypoalgesia through conditioned pain modulation? Psychophysiology, 51(3), 267–276. https://doi.org/https://doi.org/10.1111/psyp.12168
- Foxen-Craft, E., & Dahlquist, L. M. (2017). Brief submaximal isometric exercise improves cold pressor pain tolerance. Journal of Behavioral Medicine, 40(5), 760–771. https://doi.org/https://doi.org/10.1007/s10865-017-9842-2
- Gajsar, H., Nahrwold, K., Titze, C., Hasenbring, M. I., & Vaegter, H. B. (2018). Exercise does not produce hypoalgesia when performed immediately after a painful stimulus. Scandinavian Journal of Pain, 18(2), 311–320. https://doi.org/https://doi.org/10.1515/sjpain-2018-0024
- Ge, H. Y., Nie, H., Graven-Nielsen, T., Danneskiold-Samsøe, B., & Arendt-Nielsen, L. (2012). Descending pain modulation and its interaction with peripheral sensitization following sustained isometric muscle contraction in fibromyalgia. European Journal of Pain, 16(2), 196–203. https://doi.org/https://doi.org/10.1016/j.ejpain.2011.06.008
- Hoeger Bement, M. K., Rasiarmos, R. L., DiCapo, J. M., Lewis, A., Keller, M. L., Harkins, A. L., & Hunter, S. K. (2009). The role of the menstrual cycle phase in pain perception before and after an isometric fatiguing contraction. European Journal of Applied Physiology, 106(1), 105–112. https://doi.org/https://doi.org/10.1007/s00421-009-0995-8
- Hoeger-Bement, M. K., Dicapo, J., Rasiarmos, R., & Hunter, S. K. (2008). Dose response of isometric contractions on pain perception in healthy adults. Medicine and Science in Sports and Exercise, 40(11), 1880–1889. https://doi.org/https://doi.org/10.1249/MSS.0b013e31817eeecc
- Hughes, L., & Patterson, S. D. (2019). Low intensity blood flow restriction exercise: Rationale for a hypoalgesia effect. Medical Hypotheses, 132(August), 109370. https://doi.org/https://doi.org/10.1016/j.mehy.2019.109370
- Hughes, L., & Patterson, S. D. (2020). The effect of blood flow restriction exercise on exercise-induced hypoalgesia and endogenous opioid and endocannabinoid mechanisms of pain modulation. Journal of Applied Physiology, 128(4), 914–924. https://doi.org/https://doi.org/10.1152/japplphysiol.00768.2019
- Ilett, M. J., Rantalainen, T., Keske, M. A., May, A. K., & Warmington, S. A. (2019). The effects of restriction pressures on the acute responses to blood flow restriction exercise. Frontiers in Physiology, 10, 1–11. https://doi.org/https://doi.org/10.3389/fphys.2019.01018
- Jessee, M. B., Buckner, S. L., Grant Mouser, J., Mattocks, K. T., Dankel, S. J., Abe, T., Bell, Z. W., Bentley, J. P., & Loenneke, J. P. (2018). Muscle adaptations to high-load training and very low-load training with and without blood flow restriction. Frontiers in Physiology, 9, 1448. https://doi.org/https://doi.org/10.3389/fphys.2018.01448
- Jessee, M. B., Mattocks, K. T., Buckner, S. L., Dankel, S. J., Mouser, J. G., Abe, T., & Loenneke, J. P. (2018). Mechanisms of blood flow restriction: The new testament. Techniques in Orthopaedics, 33(2), 72–79. https://doi.org/https://doi.org/10.1097/BTO.0000000000000252
- Jones, M. D., Valenzuela, T., Booth, J., Taylor, J. L., & Barry, B. K. (2017). Explicit education about exercise-Induced hypoalgesia influences pain responses to acute exercise in healthy adults: A randomized controlled trial. The Journal of Pain, 18(11), 1409–1416. https://doi.org/https://doi.org/10.1016/j.jpain.2017.07.006
- Kennedy, D. L., Kemp, H. I., Ridout, D., Yarnitsky, D., & Rice, A. S. C. (2016). Reliability of conditioned pain modulation. Pain, 157(11), 2410–2419. https://doi.org/https://doi.org/10.1097/j.pain.0000000000000689
- Kim, D., Loenneke, J. P., Ye, X., Bemben D. A., Beck T. W., Larson R. D., Bemben M. G. (2017). Low-load resistance training with low relative pressure produces muscular changes similar to high-load resistance training. Muscle & Nerve, 56(6), E126–E133. https://doi.org/https://doi.org/10.1002/mus.25626
- Koltyn, K. F. (2000). Analgesia following exercise: A review. Sport Medicine, 29(2), 85–98. https://doi.org/https://doi.org/10.2165/00007256-200029020-00002
- Koltyn, K. F., Brellenthin, A. G., Cook, D. B., Sehgal, N., & Hillard, C. (2014). Mechanisms of exercise-induced hypoalgesia. The Journal of Pain, 15(12), 1294–1304. https://doi.org/https://doi.org/10.1016/j.jpain.2014.09.006.Mechanisms
- Koltyn, K. F., & Umeda, M. (2006). Exercise, hypoalgesia and blood pressure. Sports Medicine, 36(3), 207–214. https://doi.org/https://doi.org/10.2165/00007256-200636030-00003
- Koltyn, K. F., & Umeda, M. (2007). contralateral attenuation of pain after Short-Duration submaximal isometric exercise. The Journal of Pain: Official Journal of the American Pain Society, 8(11), 887–892. https://doi.org/https://doi.org/10.1016/j.jpain.2007.06.003
- Korakakis, V., Whiteley, R., & Epameinontidis, K. (2018). Blood flow restriction induces hypoalgesia in recreationally active adult male anterior knee pain patients allowing therapeutic exercise loading. Physical Therapy in Sport, 32, 235–243. https://doi.org/https://doi.org/10.1016/j.ptsp.2018.05.021
- Korakakis, V., Whiteley, R., & Giakas, G. (2018). Low load resistance training with blood flow restriction decreases anterior knee pain more than resistance training alone. A pilot randomised controlled trial. Physical Therapy in Sport, 34, 121–128. https://doi.org/https://doi.org/10.1016/j.ptsp.2018.09.007
- Kosek, E., Roos, E. M., Ageberg, E., & Nilsdotter, A. (2013). Increased pain sensitivity but normal function of exercise induced analgesia in hip and knee osteoarthritis - treatment effects of neuromuscular exercise and total joint replacement. Osteoarthritis and Cartilage, 21(9), 1299–1307. https://doi.org/https://doi.org/10.1016/j.joca.2013.06.019
- Laurentino, G. C., Ugrinowitsch, C., Roschel, H., Aoki, M. S., Soares, A. G., Neves, M., Aihara, A. Y., Da Rocha Correa Fernandes, A., & Tricoli, V. (2012). Strength training with blood flow restriction diminishes myostatin gene expression. Medicine & Science in Sports & Exercise, 44(3), 406–412. https://doi.org/https://doi.org/10.1249/MSS.0b013e318233b4bc
- Loenneke, J. P., Wilson, J. M., Balapur, A., Thrower, A. D., Barnes, J. T., & Pujol, T. J. (2012). Time under tension decreased with blood flow-restricted exercise. Clinical Physiology and Functional Imaging, 32(4), 268–273. https://doi.org/https://doi.org/10.1111/j.1475-097X.2012.01121.x
- Martín-Hernández, J., Pj, M., Menéndez, H., Ferrero, C., Jp, L., & Aj, H. (2013). Muscular adaptations after two different volumes of blood flow-restricted training. Scandinavian Journal of Medicine & Science in Sports, 23(2), 114–120. https://doi.org/https://doi.org/10.1111/sms.12036
- Meeus, M., Roussel, N. A., Truijen, S., & Nijs, J. (2010). Reduced pressure pain thresholds in response to exercise in chronic fatigue syndrome but not in chronic low back pain: An experimental study. Journal of Rehabilitation Medicine, 42(9), 884–890. https://doi.org/https://doi.org/10.2340/16501977-0595
- Millar, P. J., Bray, S. R., MacDonald, M. J., & McCartney, N. (2008). The hypotensive effects of isometric handgrip training using an inexpensive spring handgrip training device. Journal of Cardiopulmonary Rehabilitation and Prevention, 28(3), 203–207. https://doi.org/https://doi.org/10.1097/01.HCR.0000320073.66223.a7
- Montoya, A. K., & Hayes, A. F. (2016). Two-condition within-participant statistical mediation analysis. Psychological Methods, 22(1), 6–27. https://doi.org/https://doi.org/10.1037/met0000086
- Motykie, G. D., Zebala, L. P., Caprini, J. A., Lee, C. E., Arcelus, J. I., Reyna, J. J., & Cohen, E. B. (2000). A guide to venous thromboembolism risk factor assessment. Journal of Thrombosis and Thrombolysis, 9(3), 253–262. https://doi.org/https://doi.org/10.1023/A1018770712660
- Mouser, J. G., Laurentino, G. C., Dankel, S. J., Buckner, S. L., Jessee, M. B., Counts, B. R., Mattocks, K. T., & Loenneke, J. P. (2017). Blood flow in humans following low-load exercise with and without blood flow restriction. Applied Physiology, Nutrition, and Metabolism, 42(11), 1165–1171. https://doi.org/https://doi.org/10.1139/apnm-2017-0102
- Naugle, K. M., Naugle, K. E., Fillingim, R. B., & Riley, J. L. (2014). Isometric exercise as a test of pain modulation: Effects of experimental pain test, psychological variables, and sex. Pain Medicine, 15(4), 692–701. https://doi.org/https://doi.org/10.1111/pme.12312
- Ohlman, T., Miller, L., Naugle, K. E., & Naugle, K. M. (2018). Physical activity levels predict exercise-induced hypoalgesia in older adults. Medicine and Science in Sports and Exercise, 50(10), 2101–2109. https://doi.org/https://doi.org/10.1249/MSS.0000000000001661
- Ozaki, H., Yasuda, T., Ogasawara, R., Sakamaki-Sunaga, M., Naito, H., & Abe, T. (2013). Effects of high-intensity and blood flow-restricted low-intensity resistance training on carotid arterial compliance: Role of blood pressure during training sessions. European Journal of Applied Physiology, 113(1), 167–174. https://doi.org/https://doi.org/10.1007/s00421-012-2422-9
- Peterson, J. A., Schubert, D. J., Campbell, J., Bemben, M. G., & Black, C. D. (2019). Endogenous pain inhibitory function: endurance-trained athletes vs active controls. Pain Medicine, 20(9), 1822–1830. https://doi.org/https://doi.org/10.1093/pm/pnz014
- Rice, D., Nijs, J., Kosek, E., Wideman T., Hasenbring M. I., Koltyn K., Graven-Nielsen T., & Polli A. (2019). Exercise-induced hypoalgesia in pain-free and chronic pain populations: State of the art and future directions. The Journal of Pain, 20(11), 1249–1266. https://doi.org/https://doi.org/10.1016/j.jpain.2019.03.005
- Ring, C., Edwards, L., & Kavussanu, M. (2008). Effects of isometric exercise on pain are mediated by blood pressure. Biological Psychology, 78(1), 123–128. https://doi.org/https://doi.org/10.1016/j.biopsycho.2008.01.008
- Spitz, R. W., Wong, V., Bell, Z. W., Viana, R. B., Chatakondi, R. N., Abe, T., & Loenneke, J. P. (2020). Blood flow restricted exercise and discomfort. Journal of Strength and Conditioning Research. Published online. https://doi.org/https://doi.org/10.1519/jsc.0000000000003525
- Steele, J., Fisher, J., McKinnon, S., & McKinnon, P. (2016). Differentiation between perceived effort and discomfort during resistance training in older adults: Reliabilityof trainee ratings of effort and discomfort,and reliability and validity of trainer ratings of trainee effort. Journal of Trainology, 6(1), 1–8. https://doi.org/https://doi.org/10.17338/trainology.6.1_1
- Stolzman, S., & Bement, M. H. (2016). Does exercise decrease pain via conditioned pain modulation in adolescents? Pediatric Physical Therapy, 28(4), 470–473. https://doi.org/https://doi.org/10.1097/PEP.0000000000000312
- Thorén, P., Floras, J. S., Hoffmann, P., & Seals, D. R. (1990). Endorphins and exercise: Physiological mechanisms and clinical implications. Medicine & Science in Sports & Exercise, 22(4), 417–428.
- Umeda, M., Newcomb, L. W., & Koltyn, K. F. (2009). Influence of blood pressure elevations by isometric exercise on pain perception in women. International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology, 74(1), 45–52. https://doi.org/https://doi.org/10.1016/j.ijpsycho.2009.07.003
- Vaegter, H. B., Handberg, G., Emmeluth, C., & Graven-Nielsen, T. (2017). Preoperative hypoalgesia after cold pressor test and aerobic exercise is associated with pain relief 6 months after total knee replacement. The Clinical Journal of Pain, 33(6), 475–484. https://doi.org/https://doi.org/10.1097/AJP.0000000000000428
- Vaegter, H. B., Handberg, G., & Graven-Nielsen, T. (2014). Similarities between exercise-induced hypoalgesia and conditioned pain modulation in humans. Pain, 155(1), 158–167. https://doi.org/https://doi.org/10.1016/j.pain.2013.09.023
- Wang, X., Ferro, E. G., Zhou, G., Hashimoto, D., & Bhatt, D. L. (2020). Association between universal masking in a health care system and SARS-CoV-2 positivity among health care workers. JAMA, 324(7), 703–704. https://doi.org/https://doi.org/10.1056/nejmp2006372
- Yasuda, T., Ogasawara, R., Sakamaki, M., Ozaki, H., Sato, Y., & Abe, T. (2011). Combined effects of low-intensity blood flow restriction training and high-intensity resistance training on muscle strength and size. European Journal of Applied Physiology, 111(10), 2525–2533. https://doi.org/https://doi.org/10.1007/s00421-011-1873-8
- Ylinen, J., Takala, E. P., Kautiainen, H., Nykänen, M., Häkkinen, A., Pohjolainen, T., Karppi, S.-L., & Airaksinen, O. (2005). Effect of long-term neck muscle training on pressure pain threshold: A randomized controlled trial. European Journal of Pain, 9(6), 673. https://doi.org/https://doi.org/10.1016/j.ejpain.2005.01.001