Tumour-Selective Salmonella-Based Cancer Therapy

References

• Altman , E. , Roth , J.R. , Hessel , A. and Sanderson , K.E. Escherichia coli and Salmonella, cellular and molecular biology: Transposons currently in use in Salmonella species , Edited by: Neidhardt , F.C. , Curtiss III , R. , Ingraham , J.L. , Lin , E.C.C. , Low , K.B. , Magasanik , B. , Reznikoff , W.S. , Riley , M. , Schaechter , M. and Umbarger , H.E. Washington, DC : American Society for Microbiology .
   Google Scholar
• Bacon , G.A. , Burrows , T.W. and Yates , M. 1950a . The effects of biochemical mutation on the virulence of Bacterium typhosum: The induction and isolation of mutants . British Journal of Experimental Pathology , 31 : 703 – 713 .
   PubMedGoogle Scholar
• Bacon , G.A. , Burrows , T.W. and Yates , M. 1950b . The effects of biochemical mutation on the virulence of Bacterium typhosum: The virulence of mutants . British Journal of Experimental Pathology , 31 : 703 – 713 .
   PubMedGoogle Scholar
• Bacon , G.A. , Burrows , T.W. and Yates , M. 1951 . The effects of biochemical mutation on the virulence of Bacterium typhosum: The loss of virulence of certain mutants . British Journal of Experimental Pathology , 32 : 85 – 96 .
   PubMedGoogle Scholar
• Bermudes , D. , Low , B. and Pawelek , J.M. 2000a . Tumor-targeted Salmonella. Highly selective delivery vectors . Advances in Experimental Medicine and Biology , 465 : 57 – 63 .
   PubMed Web of Science ®Google Scholar
• Bermudes , D. , Low , B. and Pawelek , J. 2000b . “ Tumor-targeted Salmonella: Strain development and expression of the HSV TK effector gene ” . In Gene therapy: Methods and protocols , Edited by: Walther , W. and Stein , U. Vol. 35 , 419 – 436 . Totowa, NJ : Humana Press .
   Google Scholar
• Bochner , B.R. , Huang , H.-C. , Schieven , G.L. and Ames , B. 1980 . Positive selection for loss of tetracycline resistance . Journal of Bacteriology , 143 : 926 – 933 .
   PubMed Web of Science ®Google Scholar
• Clairmont , C. , Lee , K.C. , Pike , J. , Ittensohn , M. , Low , K.B. , Pawelek , J. , Bermudes , D. , Brecher , S.M. , Margitich , D. , Turnier , J. , Li , Z. , Luo , X. , King , I. and Zheng , L.-M. 2000 . Biodistribution and genetic stability of the novel anti-tumor agent VNP20009, a genetically modified strain of Salmonella typhimurium . Journal of Infectious Diseases , 181 : 1996 – 2002 .
   PubMed Web of Science ®Google Scholar
• Davis , R.W. , Botstein , D. and Roth , J.R. 1980 . Advanced bacterial genetics , Cold Spring Harbor : Cold Spring Harbor Laboratory Press .
   Google Scholar
• Deonarain , M.P. , Spooner , R.A. and Epenetos , A. A. 1995 . Genetic delivery of enzymes for cancer therapy . Gene. Therapy , 2 : 235 – 244 .
   PubMedGoogle Scholar
• Donnenberg , M.S. and Kaper , J.B. 1991 . Construction of an eae deletion mutant of enteropathogenic Escherichia coli by using a positive-selection suicide vector . Infection and Immunity , 59 : 4310 – 4317 .
   PubMed Web of Science ®Google Scholar
• Eisenstadt , E. , Carlton , B.C. and Brown , B.J. Methods for general and molecular bacteriology: Gene mutation , Edited by: Gerhardt , P. , Murray , R.G.E. , Wood , W. A. and Krieg , N.R. Washington, DC : American Society for Microbiology .
   Google Scholar
• Fields , P.I. , Swanson , R.V. , Haidaris , C.G. and Heffron , F. 1986 . Mutants of Salmonella typhimurium that cannot survive within the macrophage are a virulent . Proceedings of the National Academy of Sciences of the United States of America , 83 : 5189 – 5193 .
   PubMed Web of Science ®Google Scholar
• Fields , P.I. , Groisman , E.A. and Heffron , F. 1989 . A Salmonella locus that controls resistance to microbicidal proteins from phagocytic cells . Science , 243 : 1059 – 1062 .
   PubMed Web of Science ®Google Scholar
• Hall , S.S. 1995 . Monoclonal antibodies at age 20: promise at last? . Science , 270 : 915 – 916 .
   PubMedGoogle Scholar
• Hanna , N.N. , Mauceri , H.J. , Wayne , J.D. , Hallahan , D.E. , Kufe , D.W. and Weichselbaum , R.R. 1997 . Virally directed cytosine deaminase/5-fluorocytosine gene therapy enhances radiation response in human cancer xenografts . Cancer Research , 57 : 4205 – 4209 .
   PubMed Web of Science ®Google Scholar
• Hoiseth , S.K.J. and Stocker , B.A.D. 1981 . Aromatic-dependent Salmonella typhimurium are non-virulent and effective as live vaccines . Nature , 291 : 238 – 239 .
   PubMed Web of Science ®Google Scholar
• Huber , B.E. , Austin , E.A. , Richards , C.A. , Davis , S.T. and Good , S.S. 1994 . Metabolism of 5-fluorocytosine to 5-fluorouraciI in human colorectal tumor cells transduced with the cytosine deaminase gene: significant anti-tumor effects when only a small percentage of tumor cells express cytosine deaminase . Proceedings of the National Academy of Sciences of the United States of America , 91 : 8302 – 8306 .
   PubMed Web of Science ®Google Scholar
• Jain , R.K. 1994 . Barriers to drug delivery in solid tumors . Scientific American , 271 : 58 – 65 . (July)
   PubMed Web of Science ®Google Scholar
• Joiner , K.A. 1988 . Complement evasion by bacteria and parasites . Annual Review of Microbiology , 42 : 201 – 230 .
   PubMed Web of Science ®Google Scholar
• Khil , M.S. , Kim , J.H. , Mullen , C. A. , Kim , S-H. and Freytag , S.O. 1996 . Radiosensitization by 5-fluorocytosine of human colorectal carcinoma ceils in culture transduced with cytosine deaminase . Clinical Cancer Research , 2 : 53 – 57 .
   PubMed Web of Science ®Google Scholar
• King , I. , Feng , M. , Lou , X. , Lin , S. , Bermudes , D. and Zheng , L.-M. 1998 . Tumor-targeted Salmonella expressing cytosine deaminase converted 5-fluorocytosine to 5-fluorouricil and inhibited tumor growdi in vivo. Abstract #3484 . Proceedings of the American Association for Cancer Research , 39 : 512
   Google Scholar
• King , I. , Luo , X. , Feng , M. , Ittensohn , M. , Li , Z. , Belcourt , M. , Lin , S. , Le , T. , Pike , J. , Troy , K. , Sznol , M. , Clairmont , C. , Bermudes , D. and Zheng , L.-M. 2000 . Tumor therapy using Salmonella . Emerging Drugs , 5 : 211 – 219 .
   Google Scholar
• Kleckner , N. , Bender , J. and Gottesman , S. 1991 . Bacterial genetic systems: Uses of transposons with emphasis on Tn10 Edited by: Miller , J.H. Vol. 204 , 139 – 180 . Methods in Enzymology
   Google Scholar
• Lee , K.C. , Zheng , L.-M. , Xuo , x. , Clairmont , C. , Fischer , J. , Margitich , D. , Turnier , J. , Almassian , B. , Bermudes , D. and King , I. 2000 . Comparative evaluation of the acute toxic effects in monkeys, pigs, and mice of a genetically engineered Salmonella strain (VNP20009) being developed as an anti-tumor agent . International Journal ofToxicology , 19 : 19 – 25 .
   Web of Science ®Google Scholar
• Low , B. 1973 . Rapid mapping of conditional and auxotrophic mutations in Escherichia coli K-12 . Journal of Bacteriology , 113 : 798 – 812 .
   PubMedGoogle Scholar
• Low , K.B. , Ittensohn , M. , Le , T , Platt , J. , Sodi , S. , Amoss , M. , Ash , O. , Carmichael , E. , Chakraborty , A. , Fisher , J. , Lin , S.L. , Luo , X. , Miller , S.I. , Zheng , L.-M. , King , I. , Pawelek , J.M. and Bermudes , D. 1999a . Lipid A mutant Salmonella with suppressed virulence and TNFα induction retain tumor-targeting in vivo . Nature Biotechnology , 17 : 37 – 41 .
   PubMed Web of Science ®Google Scholar
• Low , K.B. , Ittensohn , M. , Lin , S. , Clairmont , C , Luo , X. , Zheng , L-M. , King , I. , Pawelek , J.M. and Bermudes , D. 1999b . VNP20009, a genetically modified Salmonella typhimurium for treatment of solid tumors. Abstract #581 . Proceedings of the American Association for Cancer Research , 40 : 87
   Google Scholar
• Luo , X. , Ittensohn , M. , Low , B. , Pawelek , J. , Li , Z. , Ma , X. , Bermudes , D. , Lin , S. , Zheng , L.-M. and King , I. 1999 . Genetically modifiedSalmonella typhimurium inhibited growth of primary tumors and metastases. Abstract #3146 . Proceedings of the American Association for Cancer Research , 40 : 476
   Google Scholar
• McGinn , C.J. , Shewach , D.S. and Lawrence , T.S. 1996 . Radiosensitizing nucleosides . Journal of the National Cancer Institute , 88 : 1193 – 1203 .
   PubMed Web of Science ®Google Scholar
• Miller , J.H. 1992 . A short course in bacterial genetics , Cold Spring Harbor : Cold Spring Harbor Laboratory .
   Google Scholar
• O’Callaghan , D. , Maskell , D. , Liew , F.Y. , Easmon , C.S.F. and Dougan , G. 1988 . Characterization of aromatic- and purine-dependent Salmonella typhimurium: Attenuation, persistence, and ability induce protective immunity in BALB/c mice . Infection and Immunity , 56 : 419 – 423 .
   PubMed Web of Science ®Google Scholar
• Pawelek , J. , Low , K.B. and Bermudes , D. 1997 . Tumor-targeted Salmonella as a novel anticancer agent . Cancer Research , 57 : 4537 – 4544 .
   PubMed Web of Science ®Google Scholar
• Peters , L.J. , Byers , R.M. and Ang , K.K. 1992 . “ Radiotherapy for Melanoma ” . In Cutaneous melanoma. , Second , Edited by: Balch , C.M. , Houghton , A.N. , Milton , G. W. , Sober , A.J. and Soong , S. 509 – 521 . Philadelphia : J.B. Lippincott & Co .
   Google Scholar
• Platt , J. , Sodi , S. , Kelley , M. , Rockwell , S. , Bermudes , D. , Low , K.B. and Pawelek , J. 2000 . Anti-tumor effects of genetically engineered Salmonella in combination with radiation . European Journal of Cancer , 36 : 2397 – 2402 .
   PubMed Web of Science ®Google Scholar
• Russell , C.B. , Thaler , D.S. and Dahlquist , F.W. 1989 . Chromosomal transformation of Escherichia coll recD- strains with linearized plasmids . Journal of Bacteriology , 171 : 2609 – 2613 .
   PubMed Web of Science ®Google Scholar
• Sambrook , J. , Fritsch , E.F. and Maniatis , T. 1989 . Molecular cloning: A laboratory manual, , 2nd , Cold Spring Harbor : Cold Spring Harbor Press .
   Google Scholar
• Steel , G.G. and Peckham , M.J. 1979 . Exploitable mechanisms in combined radiotherapy chemotherapy: The concept of additivity . International Journal of Radiation Oncology Biology and Physics , 5 : 85 – 91 .
   PubMed Web of Science ®Google Scholar
• Sternberg , N.L. and Maurer , R. 1991 . Bacteriophage-mediated generalized transduction in Escherichia coli and Salmonella typhimurium . Methods in Enzytnology , 204 : 18 – 43 .
   PubMedGoogle Scholar
• Sznol , M , Lin , S.L. , Bermudes , D. , Zheng , L.-M. and King , I. 2000 . Use of preferentially replicating bacteria for treatment of cancer . Journal of Clinical Investigation , 105 : 1027 – 1030 .
   PubMed Web of Science ®Google Scholar
• Zheng , L.-M. , Luo , X. , Fischer , J. , Le , T. , Bermudes , D. , Low , B. , Pawelek , J. and King , I. 1997 . Attenuated Salmonella typhimurium inhibited tumor metastasis in vivo. Abstract #60 . Proceedings of the American Association for Cancer Research , 38 : 9
   Google Scholar