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Food Additives & Contaminants: Part A Volume 26, 2009 - Issue 5
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Original Articles

Development and single-laboratory validation of an HPLC method for the determination of cyclamate sweetener in foodstuffs

M.J. Scotter Central Science Laboratory, Sand Hutton, York, UKCorrespondence[email protected]
,
L. Castle Central Science Laboratory, Sand Hutton, York, UK
,
D.P.T. Roberts Central Science Laboratory, Sand Hutton, York, UK
,
R. MacArthur Central Science Laboratory, Sand Hutton, York, UK
,
P.A. Brereton Central Science Laboratory, Sand Hutton, York, UK
,
S.K. Hasnip Central Science Laboratory, Sand Hutton, York, UK
&
N. Katz Central Science Laboratory, Sand Hutton, York, UK
 show all
Pages 614-622 | Received 25 Jul 2008, Accepted 14 Dec 2008, Published online: 24 Jun 2009

References

  • Alber , LL and Overton , MW . 1971 . Interference of sulphur dioxide in the determination of cyclamates by AOAC method 20.128 . J AOAC , 54 : 1499
  • Armenta , S , Garrigues , S and de la Guardia , M . 2004 . Sweeteners determination in table top formulations using FT-Raman spectrometry and chemometric analysis . Anal Chim Acta , 521 : 149 – 155 .
  • Biemer , TA . 1989 . Analysis of saccharin, acesulfame-K and sodium cyclamate by high-performance ion chromatography . J Chromatogr , 463 : 463 – 468 .
  • Cabero , C , Saurina , J and Hernandez-Cassou , S . 1999 . Flow-injection spectrophotometric determination of cyclamate in sweetener products with sodium 1,2-naphthoquinone-4 sulfonate . Anal Chim Acta , 381 : 307 – 313 .
  • Casals , I , Reixach , M , Amat , J , Fuentes , M and Serre-Majem , L . 1996 . Quantification of cyclamate and cyclohexylamine in urine samples using high-performance liquid chromatography with trinitrobenzenesulfonic acid pre-column derivatisation . J Chromatogr A , 751 : 397 – 402 .
  • CEN. 1999. Foodstuffs–Determination of cyclamte–High performance liquid chromatographic method. European Committee for Standardization. Reference number: EN 12857: 1999
  • Eurachem/CITAC. 2000. Quantifying uncertainty in analytical measurement. 2nd ed. Available from: http:www.eurachem.org/guides/quam.htm/
  • European Union . 1994 . European Parliament and Council Directive 94/35/EC of 30 June 1994 on sweeteners for use in foodstuffs . Off J , L 237 : 3 – 12 .
  • European Union . 1995 . Commission Directive 95/31/EC of 5 July 1995 laying down specific criteria of purity concerning sweeteners for use in foodstuffs . Off J , L 178 : 1 – 17 .
  • European Union . 1996 . European Parliament and Council Directive 96/83/EC of 19 December 1996 amending Directive 94/35/EC for use in foodstuffs . Off J , L 048 : 16 – 19 .
  • European Union . 2003 . European Parliament and Council Directive 2003/115/EC of 22 December 2003 amending Directive 94/35/EC for use in foodstuffs . Off J , L 024 : 65 – 71 .
  • Hauck , M and Kobler , H . 1990 . Determination of cyclamate in complex foodstuffs after derivatisation with 4-fluoro-7-nitrobenzofuran . Z Lebensm Unters Fors , 191 : 322 – 324 .
  • Herrmann , A , Damawandi , E and Wagmann , M . 1983 . Determination of cyclamate by high-performance liquid chromatography with indirect photometry . J. Chromatogr , 280 : 85 – 90 .
  • Horie , M , Ishikawa , F , Oishi , M , Shindo , T , Yasui , A and Ito , K . 2007 . Rapid determination of cyclamate in foods by solid-phase extraction and capillary electrophoresis . J Chromatogr A , 1154 : 423 – 428 .
  • Huang , ZQ , Ma , JY , Chen , B , Zhang , Y and Yao , SZ . 2006 . Determination of cyclamate in foods by high performance liquid chromatography-electrospray ionization mass spectrometry . Anal Chim Acta , 555 : 233 – 237 .
  • Johnson , DE and Nunn , HB . 1968 . Determination of cyclamates (sodium and calcium salts) in canned fruits . J AOAC , 51 : 1274 – 1277 .
  • Llamas , NE , Di Nezio , MS , Palomeque , ME and Band , BSF . 2005 . Automated turbidimetric determination of cyclamate in low calorie soft drinks and sweeteners without pre-treatment . Anal Chim Acta , 539 : 301 – 304 .
  • RSC Analytical Methods Committee. 2000. Is my calibration linear? AMC Technical Brief No. 3. Available from: http://www.rsc.org/pdf/amc/brief3.pdf/
  • Rüter , J and Raczek , D . 1992 . Sensitive and selective HPLC procedure with prechromatographical derivatisation for the determination of cyclamate in food stuffs . Z Lebensm Unters Fors , 194 : 520 – 523 .
  • Sheng , K , Chen , CJ , Ding , ZH , Sun , J , Ding , YS and Zhen , P . 2006 . Solid phase extraction-liquid chromatography/mass spectrometry for simultaneous determination of artificial synthetic sulfa sweeteners in food . Fenxi shiyanshi , 25 : 75 – 78 .
  • Wasik , A , McCourt , J and Buchgraber , M . 2007 . Simultaneous determination of nine intense sweeteners in foodstuffs by high performance liquid chromatography and evaporative light-scattering detection–development and single-laboratory validation . J Chromatogr A , 1157 : 187 – 196 .
  • Zhu , Y , Guo , YY , Ye , M and James , FS . 2005 . Separation and simultaneous determination of four artificial sweeteners in food and beverages by ion chromatography . J Chromatogr A , 1085 : 143 – 146 .

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