- BONDUELLE, S., CARRIER, M., PIMIENTA, C., BENOIT, J. P., and LENAERTS, V., 1996, Tissue concentration of nanoencapsulated radio-labelled cyclosporin following peroral delivery in mice or ophthalmic application in rabbits. European Journal of Pharmaceutics and Biopharmaceutics, 42, 313-319.
- BRANNON-PEPPAS, L., 1995, Recent advances on the use of biodegradable microparticles and nanoparticles in controlled drug delivery. International Journal of Pharmaceutics, 116,1-9.
- CALVO, P., SANCHEZ, A., MARTINEZ, J., LOPEZ, M. I., CALONGE, M., PASTOR, J. C., and ALONSO, M. J., 1996, Polyester nanocapsules as new topical ocular delivery systems for cyclosporin A. Pharmaceutical Research, 13, 311-315.
- CHA, Y., and PITT, C. G., 1988, A one-week subdermal delivery system for L-methadone based on biodegradable microcapsules. Journal of Controlled Release, 7, 69-78.
- CHACON, M., BERGES, L., MOLPECERES, J., ABERTURAS, M. R., and GUZMAN, M., 1996, Optimized preparation of poly DL(lactic-glycolic) microspheres and nanoparticles for oral administration. International Journal of Pharmaceutics, 141, 81-91.
- CHACON, M., MOLPECERES, J., BERGES, L., GUZMAN, M., and ABERTURAS, M. R., 1999, Stability and freeze-drying of cyclosporine loaded poly(D,L lactide-glycolide) carriers. European Journal of Pharmaceutical Sciences, 8, 99-107.
- COFFIN, M. D., and McGINITY, J. W., 1992, Biodegradable pseudolatexes: the chemical stability of poly(D,L-lactide) and poly(e-caprolactone) nanoparticles in aqueous media. Pharmaceutical Research, 9, 200-205.
- COUVREUR, P., and PUISIEUX, F., 1993, Nano- and micro-particles for the delivery of polypeptides and proteins. Advanced Drug Delivery Reviews, 10, 141-162.
- CROWE, L. M., REID, D. S., and CROWE, J. H., 1996, Is trehalose special for preserving dry biomaterials? Biophysical Journal, 71, 2087-2093.
- DE CHASTEIGNER, S., CAVE, G., FESSI, H., DEVISSAGUET, J. P., and PUISIEUX, F., 1996, Freeze-drying of itraconazole-loaded nanosphere suspensions: a feasability study. Drug Development and Research, 38, 116-124.
- DE JAEGHERE, F., ALLÉMANN, E., LEROUX, J. C., STEVELS, W., FEIJEN, J., DOELKER, E., and GURNY, R., 1999, Formulation and lyoprotection of poly (lactic acid-co-ethylene oxide) nanoparticles: Influence on physical stability and in vitro cell uptake. Pharmaceutical Research, 16, 859-866.
- ESQUISABEL, A., HERNANDEZ, R. M., IGARTUA, M., GASCÓN, A. R., CALVO, B., and PEDRAZ, J. L., 1997, Production of BCG alginate-PLL microcapsules by emulsification/internal gelation. Journal of Microencapsulation, 14, 627-638.
- FAHR, A., 1993, Cyclosporin clinical pharmacokinetics. Clinical Pharmacokinetics, 24, 472-495.
- FANG, J. Y., LIN, H. H., Hsu, L. R., and TSAI, Y. H., 1997, Characterization and stability of various liposome-encapsulated enoxacin formulations. Chemical and Pharmaceutical Bulletin, 45, 1504-1509.
- FAULDS, D., GOA, K. L., and BENELD, P., 1993, Cyclosporin: a review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in immunoregulatory disorders. Drugs, 45, 953-1040.
- FLORENCE, A. T., 1997, The oral absorption of micro- and nanoparticulates: neither exceptional nor unusual. Pharmaceutical Research, 14, 259-266.
- GUTERRES, S. S., FESSI, H., BARRAT, G., DEVISSAGUET, J. P., and PUISIEUX, F., 1995, poly(oL-lactide) nanocapsules containing diclofenac: I. Formulation and stability study.International Journal of Pharmaceutics, 113, 57-63.
- GUZMÁN, M., MOLPECERES, J., GARCIA, F., ABERTURAS, M. R., and RODRIGUEZ, M., 1993, Formation and characterization of cyclosporine-loaded nanoparticles. Journal of Pharmaceutical Sciences, 82, 498-502.
- HINTZE, J. L., 1992, NCSS 5. X series, Utah, USA. LEMOINE, D., FRANCOIS, C., KEDZIEREWICZ, F., PREAT, V., HUFFMAN, M., and MAINCENT, P., 1996, Stability study of nanoparticles of poly(e-caprolactone), poly(D,L-lactide) and poly(D,L-lactide-co-glycolide). Biomaterials, 17, 2191-2197.
- LIN, W. J., FLANAGAN, D. R., and LINHARDT, R. J., 1994, Accelerated degradation of polyfecaprolactone) by organic amines. Pharmaceutical Research, 11, 1030-1034.
- MAULDING, H. V., TICE, T. R., COWSAR, D. R., FONG, J. W., PEARSON, J. E., and NAZARENO, J. P., 1986, Biodegradable microcapsules: acceleration of polymeric excipient hydrolytic rate by incorporation of a basic medicament. Journal of Controlled Release, 3, 103-117.
- MOLPECERES, J., ABERTURAS, M. R., and GUZMAN, M., 2000, Biodegradable nanoparticles as a delivery system for cyclosporine: preparation and characterization. Journal of Microencapsulation, 17, 599-614.
- OKADA, H., and TOGUCHI, H., 1995, Biodegradable microspheres in drug delivery. Critical Reviews on Therapuetic Drug Carrier Systems, 12, 1-99.
- SANCHEZ, A., and ALONSO, M. J., 1995, Poly(D,L-Lactide-co-glycolide) micro and nanospheres as a way to prolong blood/plasma levels of subcutaneously injected cyclosporin A. European Journal of Pharmaceutics and Biopharmaceutics, 41, 27-37.
- VERT, M., Li, S., and GARREAU, H., 1991, More about the degradation of LA/GA-derived matrices in aqueous media. Journal of Controlled Release, 16, 15-26.
Development of a new cyclosporine formulation based on poly(caprolactone) microspheres
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