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Journal of Microencapsulation
Micro and Nano Carriers
Volume 20, 2003 - Issue 4
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Research Article

The characteristics of betamethasone-loaded chitosan microparticles by spray-drying method

Y.-C. Huang Graduate Institute of Life Sciences, National Defense Medical Center, University of National Defense, Taipei, Taiwan
,
M.-K. Yeh Department of Pediatric and Medical Research, Tri-service General Hospital, National Defense Medical Center, University of National Defense, Taipei, Taiwan
,
S.-N. Cheng Department of Pediatric and Medical Research, Tri-service General Hospital, National Defense Medical Center, University of National Defense, Taipei, Taiwan
&
C.-H. Chiang School of Pharmacy, National Defense Medical Center, University of National Defense, Taipei, TaiwanCorrespondence[email protected]
Pages 459-472 | Received 11 Jun 2003, Accepted 11 Jun 2003, Published online: 11 Jun 2003

  • GIUNCHEDI, P., GENTA, I. CONTI, B., MUZZARELLI, R. A. and CONTE, U., 1998, Preparation and characterization of ampicillin loaded methylpyrrolidinone chitosan and chitosan microspheres. Biomaterials, 19, 157-161.
  • FILIPOVIC-GRCIC, J., VOINOVICH, D., MONEGHINI, M., BECIREVIC-LACAN, M., MAGAROTTO, L. and JALSENJAK, I., 2000, Chitosan microspheres with hydrocortisone and hydrocortisone-hydroxypropyl-beta-cyclodextrin inclusion complex. European Journal of Pharmaceutical Sciences, 9, 373-379.
  • HE, P., DAVIS, S. S. and ILLUM, L., 1999, Chitosan microspheres prepared by spray drying. International Journal of Pharmaceutics, 187, 53-65.
  • HUANG, Y. C., CHIANG, C. H. and YEH, M. K., 2002a, Optimizing formation factors in preparing chitosan microparticles by spray-drying method. Journal of Micro-encapsulation, in press.
  • Huang, Y. C., Chiang, C. H. and YEH, M. K., 2002b, Formulation factors in preparing BTM-chitosan microspheres by spray drying method. International Journal of Pharmaceutics, 242, 239-242.
  • ILLUM, L., 1998, Chitosan and its use as a pharmaceutical excipient. Pharmaceutical Research, 15, 1326-1331.
  • KAS, H. S., 1997, Chitosan: properties, preparations and application to microparticulate systems. Journal of Microencapsulation, 14, 689-711.
  • KORTESUO, P., AHOLA, M., KANGAS, M., KANGASNIEMI, I., YLI-URPO, A. and KIESVAARA, J., 2000. In vitro evaluation of sol-gel processed spray dried silica gel microspheres as carrier in controlled drug delivery. International Journal of Pharmaceutics, 200, 223-229.
  • AHSAN, F., RIVAS, I. P., KHAN, M. A. and SUAREZ, A., 2002, Targeting to macrophages:role of physicochemical properties of paniculate carriers-liposomes and microspheres-on the phagocytosis by macrophages. Journal of Controlled Release, 79, 29-40.
  • BAIN, D. F., MUNDAY, D. L. and SMITH, A., 1999a, Modulation of rifampicin release from spray-dried microspheres using combinations of poly-(DL-lactide). Journal of Microencapsulation, 16, 369-385.
  • BAIN, D. F., MUNDAY, D. L. and SMITH, A., 1999b, Solvent influence on spray-dried biodegradable microspheres. Journal of Microencapsulation, 16, 453-474.
  • BEN-JEBRIA, A., CHEN, D., ESKEW, M. L., VANBEVER, R., LANGER, R. and EDWARDS, D. A., 1999, Large porous particles for sustained protection from carbachol-induced bronchoconstriction in guinea pigs. Pharmaceutical Research, 16, 551-561.
  • CARLVO, P., REMUÑAN-LOPEZ, C., VILA-JATO, J. L. and ALONSO, M. J., 1997, Chitosan and chitosan/ethylene oxide-propylene oxide block copolymer nanoparticles as novel carriers for proteins and vaccines. Pharmaceutical Research, 14, 1431-1436.
  • CHANG, H. C. and Li, L. C., 2000, Sustained-release butorphanol microparticles. Drug Development & Industrial Pharmacy, 26, 829-835.
  • CHEW, Y. K. and CHAN, H. K., 2001, Use of solid corrugated particles to enhance powder aerosol performance. Pharmaceutical Research, 18, 1570-1577.
  • EWARDS, D. A., HANES, J., CAPONETTI, G., HRKACH, J., BEN-JEBRIA, A., ESKEW, M. L.,MINTZES, J., DEAVER, D., LOTAN, N. and LANGER, R., 1997, Large porous particles for pulmonary drug delivery. Science, 276, 1868-1871.
  • Di MARTINO, P., SCOPPA, M., JOIRIS, E., PALMIERI, G. F., ANDRES, C., POURCELOT, Y. and MARTELLI, S., 2001, The spray drying of acetazolamide as method to modify crystal properties and to improve compression behaviour. International Journal of Pharmaceutics, 213, 209-221.
  • LEFFLER, C. C. and MULLER, B. W., 2000, Influence of the acid type on physical and drug liberation properties of chitosan-gelatin sponge. International Journal of Pharmaceutics, 194, 229-237.
  • MAA, Y. F. and PRESTRELSKI, S. J., 2000, Biopharmaceutical powders: particle formation and formulation considerations. Current Pharmaceutical Biotechnology, 1, 283-302.
  • MOOREN, F. C., BERTHOLD, A., DOMSCHKE, W. and KREUTER, J., 1998, Influence of chitosan microspheres on the transport of prednisolone sodium phosphate across HT-29 cell monolayers. Pharmaceutical Research, 15, 58-65.
  • O'HARA, P. and HICKEY, A. J., 2000, Respirable PLGA microspheres containing rifampicin for the treatment of tuberculosis: manufacture and characterization. Pharmaceutical Research, 17, 955-961.
  • PAVANETTO, F., GENTA, I., GIUNCHEDI, P., CONTI, B. and CONTE, U., 1994, Spray-dried albumin microspheres for the intra-articular delivery of dexamethasone. Journal of Microencapsulation, 11, 445-454.
  • PRIOR, S., GAMAZO, C., IRACHE, J. M., MERKLE, H. P. and GANDER, B., 2000, Gentamicin encapsulation in PLA/PLGA microspheres in view of treating Brucella infections. International Journal of Pharmaceutics, 196, 115-125.
  • ROSER, M., FISCHER, D. and KISSEL, T., 1988, Surface modified biodegradable albumin nano- and microspheres. II: effect of surface charges on in vitro phagocytosis and biodistribution in rats. European Journal of Pharmaceutics and Biopharmaceutics, 4, 255-263.
  • SMITH, S. J. and BERNSTEIN, J. A., 1996, Therapeutic uses of lung aerosols. Inhalation Aerosols edited by A. Hickey (New York: Marcel Dekker Inc.), pp. 233-261.
  • TAKATA, Y. and IKADA, Y., 1988, Effect of the size and surface charge of polymer microspheres on their phagocytosis by macrophage. Biomaterials, 9, 356-362.
  • THACHARODI, D. and RAO, K. P., 1995, Collagen-chitosan composite membranes for controlled release of propranolol hydrochloride. International Journal of Pharmaceutics, 120, 115-118.
  • VANBEVER, R., MINTZES, J. D., WANG, J., NICE, J., CHEN, D., BATYCKY, R., LANGER, R. and EDWARDS, D. A., 1999, Formulation and physical characterization of large porous particles for inhalation. Pharmaceutical Research, 16, 1735-1742.
  • ZGOULLI, S., GREK, V., BARRE, G., GOFFINET, G., THONART, P. and ZINNER, S., 1999, Microencapsulation of erythromycin and clarithromycin using a spray-drying technique. Journal of Microencapsulation, 16, 565-571.

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