Advanced search
Publication Cover
Journal of Microencapsulation
Micro and Nano Carriers
Volume 21, 2004 - Issue 1
Submit an article Journal homepage
170
Views
16
CrossRef citations to date
0
Altmetric
Research Article

Gastrointestinal absorption enhancement of insulin by administration of enteric microspheres and SNAC to rats

R. Qi Department of Pharmaceutics, China Pharmaceutical University, Nanjing, 210009, P. R. ChinaCorrespondence[email protected]
&
Q. N. Ping Department of Pharmaceutics, China Pharmaceutical University, Nanjing, 210009, P. R. China
Pages 37-45 | Received 15 May 2003, Accepted 20 Jul 2003, Published online: 03 Oct 2008

References

  • BRAYDEN, D., CREED, E., CONNELL, A. 0., LEIPOLD, H., AGARWAL, R. and Leone-BAY, A., 1997, Heparin absorption across the intestine: effects of sodium N-[8-(2-hydroxybenzoyl) amino] caprylate in rat in situ intestinal instillations and in Caco-2 monolayers. Pharmaceutical Research, 14, 1772–1779.
  • CARINO, G. P. and MATHIOWITZ, E., 1999, Oral insulin delivery. Advanced Drug Delivery Reviews, 35, 249–257.
  • CHUNG, T. W., HUANG, Y. Y., TSAI, Y. L. and Liu, Y. Z., 2001, Effects of solvent evaporation rate on the properties of protein-loaded PLLA and PDLLA microspheres fabricated by emulsion-solvent evaporation process. Journal of Microencapsulation, 19, 463–471.
  • UN, S. Y., TNAN, Y. L., LEE, C. J. and WENG, C. N., 1991, Preparation of enteric-coated microspheres of mycoplasma hyopneumoniae vaccine with cellulose acetate phthalate: I. Formation condition and micromeritic properties. Journal of Microencapsulation, 8, 317–325.
  • MORISHITA, I., MORISHITA, M., TAKAYAMA, K., MACHIDA, Y. and NAGAI, T., 1993, Enteral insulin delivery by microspheres in 3 different formulations using Eudragit L100 and S100. International Journal of Pharmaceutics, 91, 29–37.
  • MLYNEK, G. M., CALVO, L. J. and ROBINSON, J. R., 2000, Carrier-enhanced human growth hormone absorption across isolated rabbit intestinal tissue. International Journal of Pharmaceutics, 179, 13–21.
  • NAGAREYA, N., UCHIDA, T. and MATSUYAMA, K., 1993, Preparation and characterization of enteric microspheres containing bovine insulin by a w/o/w emulsion solvent evaporation method. Chemical Pharmaceutical Bulletin, 46, 1613–1617.
  • STOLL, B. R., LEIPOLD, H. R., MILSTEIN, S. and EDWARDS, D.A., 2000, A mechanistic analysis of carrier-mediated oral delivery of protein therapeutics. Journal of Controlled Release, 64, 217–228.
  • Wu, S. J. and ROBINSON, J. R., 1999, Transport of human growth hormone across Caco-2 cells with novel delivery agents:evidence for P-glycoprotein involvement. Journal of Controlled Release, 62, 171–177.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.