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Research Article

Formulation, characterisation and in vivo evaluation of lipid-based nanocarrier for topical delivery of diflunisal

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Pages 475-486 | Received 28 Mar 2016, Accepted 19 Jul 2016, Published online: 08 Aug 2016

References

  • Abdelbary G, Fahmy RH. Diazepam loaded solid lipid nanoparticles: Design and characterization. AAPS PharmSciTech, 2009;10:211–19.
  • Aggarwal N, Goindi S. Development of hydroalcoholic gels of griseofulvin containing terpenes for the treatment of topical fungal infections. Int J Res Pharm Biomed Sci, 2012a;3:1415–23.
  • Aggarwal N, Goindi S. Preparation and evaluation of antifungal efficacy of griseofulvin loaded deformable membrane vesicles in optimized guinea pig model of Microsporum canis-dermatophytosis. Int J Pharm, 2012b;437:277–87.
  • Aggarwal N, Goindi S. Preparation and in vivo evaluation of solid lipid nanoparticles of griseofulvin for dermal use. J Biomed Nanotechnol, 2013a;9:564–76.
  • Aggarwal N, Goindi S. Dermatokinetic and pharmacodynamic evaluation of ethosomes of griseofulvin designed for dermal delivery. J Nanopart Res, 2013b;15:1–15.
  • Akhtar MH, Ahmad A, Ali J, Mohan G. Formulation and development of CoQ10-loaded s-SNEDDS for enhancement of oral bioavailability. J Pharm Innov, 2014;9:121–31.
  • Appleton I, Nash PRC, Alam CA, Brown JR, Seed MP, Willoughby DA. The pharmacological modulation of angiogenesis in chronic granulomatous inflammation. J Pharmacol Exp Ther, 1995;274:1463–72.
  • Asuzu IU, Sosa S, Della Loggia R. The anti-inflammatory activity of Icacina trichantha tuber. Phytomedicine, 1999;6:267–72.
  • Atta AH, Alkofahi A. Anti-nociceptive and anti-inflammatory effects of some Jordanian medicinal plant extracts. J Ethnopharmacol, 1998;60:117–24.
  • Berkman MS, Yazan Y. Solid lipid nanoparticles: A possible vehicle for zinc oxide and octocrylene. Pharmazie, 2012;67:202–8.
  • Binny K, Kumar GS, Thomas D. Anti-inflammatory and antipyretic properties of the rhizome of costus speciosus (Koen.) SM. J Basic Clin Pharm, 2010;1:177–81.
  • Bolzinger MA, Briancon S, Pelletier J, Fessi H, Chevalier Y. Percutaneous release of caffeine from microemulsion, emulsion and gel dosage forms. Eur J Pharm Biopharm, 2008;68:446–51.
  • Braun E, Wagner A, Furnschlief E, Katinger H, Vorauer Uhl K. Experimental design for in vitro skin penetration study of liposomal superoxide dismutase. J Pharm Biomed Anal, 2006;40:1187–97.
  • Caboi F, Lazzari P, Pani L, Monduzzi M. Effect of 1-butanol on the microstructure of lecithin/water/tripalmitin system. Chem Phys Lipids, 2005;135:147–56.
  • Cashin CH, Dawson W, Kitchen EA. The pharmacology of benoxaprofen (2-[4-chlorophenyl]-alpha-methyl-5-benzoxazole acetic acid), LRCL 3794, a new compound with anti-inflammatory activity apparently unrelated to inhibition of prostaglandin synthesis. J Pharm Pharmacol, 1977;29:330–6.
  • Chen H, Chang X, Du D, Liu W, Liu J, Weng T, Yang Y, Xu H, Yang X. Podophyllotoxin-loaded solid lipid nanoparticles for epidermal targeting. J Control Release, 2006;110:296–306.
  • Das MK, Palei NN. Sorbitan ester niosomes for topical delivery of rofecoxib. Indian J Exp Biol, 2011;49:438–45.
  • Deepak K, Wavikar P, Vavia P. Niosomal gel of lornoxicam for topical delivery: In vitro assessment and pharmacodynamic activity. AAPS PharmSciTech, 2013;14:1072–82.
  • Desai P, Patlolla RR, Singh M. Interaction of nanoparticles and cell-penetrating peptides with skin for transdermal drug delivery. Mol Membr Biol, 2010;27:247–59.
  • Esser RE, Molteni RM, Sharr M, Zhang X, Porter W, Ramosb L, Jeffrey A, Cramer B, Zhuang BS, Georgieva CA, Maniara W. Pharmacodynamic behaviour of the selective cyclooxygenase-2 inhibitor lumiracoxib in the lipopolysaccharide-stimulated rat air pouch model. Eur J Pharm Sci, 2005;25:25–30.
  • Fang J, Fang C, Liu C, Su Y. Lipid nanoparticles as vehicles for topical psoralen delivery: Solid lipid nanoparticles (SLN) versus nanostructured lipid carriers (NLC). Eur J Pharm Biopharm, 2008;70:633–40.
  • Farboud ES, Nasrollahi SA, Tabbakhi Z. Novel formulation and evaluation of a Q10-loaded solid lipid nanoparticle cream: In vitro and in vivo studies. Int J Nanomed, 2011;6:611–17.
  • Forbes JA, Beaver WT, White EH, White RW, Neilson GB, Shackleford RW. Diflunisal. A new oral analgesic with an unusually long duration of action. JAMA, 1982;248:2139–42.
  • Gandomia N, Aboutaleba E, Nooria M, Atyabib F, Fazelic MR, Farbodd E, Jamalifarc H, Dinarvand R. Solid lipid nanoparticles of ciprofloxacin hydrochloride with enhanced antibacterial activity. J Nanosci Lett, 2012;2:21–8.
  • Gasco MR. Method for producing solid lipid microspheres having a narrow size distribution. United States Patent, USS 188837; 1993.
  • Ghadiri M, Fatemi S, Vatanara A, Doroud D, Najafabadi AR, Darabi M, Rahimi AA. Loading hydrophilic drug in solid lipid media as nanoparticles: Statistical modeling of entrapment efficiency and particle size. Int J Pharm, 2012;424:128–37.
  • Hannah J, Ruyle WV, Jones H, Matzuk AR, Kelly KW, Witzel BE, Holtz WJ, Houser RW, Shen TY, Sarett LH. Discovery of diflunisal. Br J Clin Pharmacol, 1977;4:7S–13.
  • Hannah J, Ruyle WV, Jones H, Matzuk AR, Kelly KW, Witzel BE, Holtz WJ, Houser RW, Shen TY, Sarett LH. Novel analgesic anti-inflammatory salicylates. J Med Chem, 1978;21:1093–100.
  • Jain S, Jain P, Jain NK, Umamaheshwari RB. Transfersomes-a novel vesicular carrier for enhanced transdermal delivery: Development, characterization, and performance evaluation. Drug Dev Ind Pharm, 2003;29:1013–26.
  • Jenning V, Schäfer-Korting M, Gohla S. Vitamin A-loaded solid lipid nanoparticles for topical use: Drug release properties. J Control Release, 2000;66:115–26.
  • Joshi M, Patravale V. Nanostructured lipid carrier (NLC) based gel of celecoxib. Int J Pharm, 2008;346:124–32.
  • Küchler S, Herrmann W, Panek-Minkin G, Blaschke T, Zoschke C, Kramer KD, Bittl R, Schäfer-Korting M. SLN for topical application in skin diseases. Characterization of drug–carrier and carrier–target interactions. Int J Pharm, 2010;390:225–33.
  • Küchler S, Radowski MR, Blaschke T, Dathe M, Plendl J, Haag R, Schäfer-Korting M, Kramer KD. Nanoparticles for skin penetration enhancement – a comparison of a dendritic core-multishell-nanotransporter and solid lipid nanoparticles. Eur J Pharm Biopharm, 2009;71:243–50.
  • Kumar N, Shishu. D-optimal experimental approach for designing topical microemulsion of itraconazole: Characterization and evaluation of antifungal efficacy against a standardized Tinea pedis infection model in Wistar rats. Eur J Pharm Sci, 2015;67:112–19.
  • Lawrence MJ, Rees GD. Microemulsion-based media as novel drug delivery systems. Adv Drug Deliv Rev, 2000;45:89–121.
  • Liu J, Hu W, Chen H, Ni Q, Xu H, Yang X. Isotretinoin-loaded solid lipid nanoparticles with skin targeting for topical delivery. Int J Pharm, 2007;328:191–5.
  • Liu Y, Wang L, Zhao Y, He M, Zhang X, Niu M, Feng N. Nanostructured lipid carriers versus microemulsions for delivery of the poorly water-soluble drug luteolin. Int J Pharm, 2014;476:169–77.
  • Lu HM, Liang YZ, Yi LZ, Wu XJ. Anti-inflammatory effect of Houttuynia cordata injection. J Ethnopharmacol, 2006;104:245–9.
  • Lv Q, Yu A, Xi Y, Li H, Song Z, Cuic J, Cao F, Zhai G. Development and evaluation of penciclovir-loaded solid lipid nanoparticles for topical delivery. Int J Pharm, 2009;372:191–8.
  • Maia CS, Mehnert W, Schafer-Korting M. Solid lipid nanoparticles as drug carriers for topical glucocorticoids. Int J Pharm, 2000;196:165–7.
  • Mandawgade SD, Patravale VB. Development of SLNs from natural lipids: Application to topical delivery of tretinoin. Int J Pharm, 2008;363:132–8.
  • Manjunath K, Reddy JS, Venkateswarlu V. Solid lipid nanoparticles as drug delivery systems. Methods Find Exp Clin Pharmacol, 2005;27:127–44.
  • Masferrer JL, Smith CJ, Zhang Y, Koboldt CM, Muhammad J, Zweifel BS, Shaffer A, Talley JJ, Seibert K, Isakson PC. Pharmacological analysis of cyclooxygenase-1 in inflammation. Proc Natl Acad Sci USA, 1994;95:13313–18.
  • Mehnert W, Mader K. Solid lipid nanoparticles: Production, characterization and applications. Adv Drug Deliv Rev, 2001;47:165–96.
  • Mei Z, Chen H, Weng T, Yang Y, Yang X. Solid lipid nanoparticle and microemulsion for topical delivery of triptolide. Eur J Pharm Biopharm, 2003;56:189–96.
  • Mishra NK, Allan JJ. Evaluation of anti-inflammatory activity and potency of herbal formulation consists of different proportions of Curcuma longa and Boswellia serrata by using cotton pellet granuloma and xylene induced mice ear edema model. Int J Pharm Tech Res, 2010;2:855–60.
  • Mojahediana MM, Daneshamouz S, Samanib SM, Zargarana A. A novel method to produce solid lipid nanoparticles using n-butanol as an additional co-surfactant according to the o/w microemulsion quenching technique. Chem Phys Lipids, 2013;174:32–8.
  • Müller RH, Mäder K, Gohla S. Solid lipid nanoparticles (SLN) for controlled drug delivery – a review of the state of the art. Eur J Pharm Biopharm, 2000;50:161–77.
  • Muller RH, Shegokar R, Keck CM. Years of lipid nanoparticles (SLN and NLC): Present state of development and industrial applications. Curr Drug Discov Technol, 2011;8:207–27.
  • Okoli CO, Akah PA, Onuoha NJ, Okoye TC, Nwoye AC, Nworu CS. Acanthus montanus: An experimental evaluation of the antimicrobial, anti-inflammatory and immunological properties of a traditional remedy for furuncles. BMC Complement Altern Med, 2008;8:1–11.
  • Raza K, Singh B, Mahajan A, Negi P, Bhatia A, Katare OP. Design and evaluation of flexible membrane vesicles (FMVs) for enhanced topical delivery of capsaicin. J Drug Target, 2011;19:293–302.
  • Raza K, Singh B, Singla S, Wadhwa S, Garg B, Chhibber S, Katare OP. Nanocolloidal carriers of isotretinoin: Antimicrobial activity against propionibacterium acnes and dermatokinetic modeling. Mol Pharm, 2013;10:1958–63.
  • Romano M, Faggioni CA, Sironi M, Sacco S, Echtenacher B, Santo ED,Salmona M, Ghezzi P. Carrageenan-induced acute inflammation much air pouch synovial model. Role of tumor necrosis factor. Mediat Inflamm, 1997;6:32–8.
  • Sayar K, Melli M. Effect of combination of misoprostol and indomethacin on eicosanoid production in carrageenan-induced air pouch inflammation in rats. Eur J Pharmacol, 1999;369:365–71.
  • Schäfer-Korting M, Mehnert W, Korting HC. Lipid nanoparticles for improved topical application of drugs for skin diseases. Adv Drug Deliv Rev, 2007;59:427–43.
  • Sedgwick AD, Sin YM, Edwards JCW, Willough DA. Increased inflammatory reactivity in newly formed lining tissue. J Pathol, 1983;141:483–95.
  • Shidhaye SS, Vaidya R, Sutar S, Patwardhan A, Kadam VJ. Solid lipid nanoparticles and nanostructured lipid carriers – innovative generations of solid lipid carriers. Curr Drug Deliv, 2008;5:324–31.
  • Stecova J, Mehnert W, Blaschke T, Kleuser B, Sivaramakrishnan R, Zouboulis CC, Seltmann H, Korting HC, Kramer KD, Schafer-Korting M. Cyproterone acetate loading to lipid nanoparticles for topical acne treatment: Particle characterisation and skin uptake. Pharm Res, 2007;24:991–1000.
  • Venter J, Muller D, Plessis JD, Goosen C. A comparative study of an in situ adapted diffusion cell and an in vitro Franz diffusion cell method for transdermal absorption of doxylamine. Eur J Pharm Sci, 2001;13:169–77.
  • Wissing SA, Müller RH. The influence of solid lipid nanoparticles on skin hydration and viscoelasticity-in vivo study. Eur J Pharm Biopharm, 2003;56:67–72.
  • Yoon G, Park JW, Yoon I. Solid lipid nanoparticles (SLNs) and nanostructured lipid carriers (NLCs): Recent advances in drug delivery. J Pharm Invest, 2013;43:353–62.
  • Yun H, Choi YW, Kim NJ, Sohn D, Yun H, Choi YW, Kim NJ, Sohn D. Physiochemical properties of phosphatidylcholine monolayers with different alkyl chains at the air/water interface. Bull Korean Chem Soc, 2003;24:377–83.
  • Zhao X, Liu JP, Zhang X, Li Y. Enhancement of transdermal delivery of theophylline using microemulsion vehicle. Int J Pharm, 2006;327:58–64.

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