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Original Articles

Novel revaprazan-loaded gelatin microsphere with enhanced drug solubility and oral bioavailability

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Pages 421-427 | Received 06 Mar 2018, Accepted 21 Aug 2018, Published online: 09 Oct 2018

References

  • Cho, J.H., et al., 2014. Development of novel fast-dissolving tacrolimus solid dispersion-loaded prolonged release tablet. European journal of pharmaceutical sciences: official journal of the european federation for pharmaceutical sciences, 54, 1–7.
  • Choi, H.Y., et al., 2012. Bioavailability and tolerability of combination treatment with revaprazan 200 mg + itopride 150 mg: a randomised crossover study in healthy male Korean volunteers. Clinical therapeutics, 34 (9), 1999–2010.
  • Inatomi, N., et al., 2016. Potassium-competitive acid blockers: advanced therapeutic option for acid-related diseases. Pharmacology and therapeutics, 168, 12–22.
  • Joe, J.H., et al., 2010. Effect of the solid-dispersion method on the solubility and crystalline property of tacrolimus. International journal of pharmaceutics, 395 (1–2), 161–166.
  • Kim, D.S., et al., 2016a. Comparison of solvent-wetted and kneaded l-sulpiride-loaded solid dispersions: powder characterization and in vivo evaluation. International journal of pharmaceutics, 511 (1), 351–358.
  • Kim, D.S., et al., 2016b. Development of a novel l-sulpiride-loaded quaternary microcapsule: effect of TPGS as an absorption enhancer on physicochemical characterization and oral bioavailability. Colloids and surfaces. B, biointerfaces, 147, 250–257.
  • Kim, D.W., et al., 2014. Comparison of a solid SMEDDS and solid dispersion for enhanced stability and oral absorption of clopidogrel napadisilate. Carbohydrate polymers, 114, 365–374.
  • Kim, J.C., et al., 2016. Effect of HM30181 mesylate salt-loaded microcapsules on the oral absorption of paclitaxel as a novel P-glycoprotein inhibitor. International journal of pharmaceutics, 506 (1–2), 93–101.
  • Kim, K.S., et al., 2015. Novel fenofibric acid-loaded controlled release pellet bioequivalent to choline fenofibrate-loaded commercial product in beagle dogs. International journal of pharmaceutics, 490 (1–2), 273–280.
  • Kim, K.S., et al., 2016. Development of novel prasugrel base microsphere-loaded tablet with enhanced stability: physicochemical characterization and in vivo evaluation in beagle dogs. Colloids surf B biointerfaces, 146, 754–761.
  • Lee, J.S., et al., 2012. Revaprazan, a novel acid pump antagonist, exerts anti-inflammatory action against Helicobacter pylori-induced COX-2 expression by inactivating Akt signaling. Journal of clinical biochemistry and nutrition, 51 (2), 77–83.
  • Lee, S.N., et al., 2013. A novel surface-attached carvedilol solid dispersion with enhanced solubility and dissolution. Archives of pharmacal research, 36 (1), 79–85.
  • Li, D.X., et al., 2008. Novel gelatin microcapsule with bioavailability enhancement of ibuprofen using spray-drying technique. International journal of pharmaceutics, 355 (1–2), 277–284.
  • Li, D.X., et al., 2010a. Development of an itraconazole-loaded gelatin microcapsule with enhanced oral bioavailability: physicochemical characterization and in-vivo evaluation. The journal of pharmacy and pharmacology, 62 (4), 448–455.
  • Li, D.X., et al., 2010b. Development of valsartan-loaded gelatin microcapsule without crystal change using hydroxypropylmethylcellulose as a stabilizer. Drug delivery, 17 (5), 322–329.
  • Li, W., et al., 2014. Influence of drug physicochemical properties on absorption of water insoluble drug nanosuspensions. International journal of pharmaceutics, 460 (1-2), 13–23.
  • Li, W., et al., 2011. Preparation and in vitro/in vivo evaluation of revaprazan hydrochloride nanosuspension. International journal of pharmaceutics, 408 (1–2), 157–162.
  • Marasini, N., et al., 2013. Fabrication and evaluation of pH-modulated solid dispersion for telmisartan by spray-drying technique. International journal of pharmaceutics, 441 (1–2), 424–432.
  • Mustapha, O., et al., 2016. Novel piroxicam-loaded nanospheres generated by the electrospraying technique: physicochemical characterisation and oral bioavailability evaluation. Journal of microencapsulation, 33 (4), 323–330.
  • Park, J.H., et al., 2018. Comparison of a revaprazan-loaded solid dispersion, solid SNEDDS and inclusion compound: physicochemical characterisation and pharmacokinetics. Colloids and surfaces. B, biointerfaces, 162, 420–426.
  • Rashid, R., et al., 2015a. Comparative study on solid self-nanoemulsifying drug delivery and solid dispersion system for enhanced solubility and bioavailability of ezetimibe. International journal of nanomedicine, 10, 6147–6159.
  • Rashid, R., et al., 2015b. Effect of hydroxypropylcellulose and Tween 80 on physicochemical properties and oral absorption of ezetimibe-loaded solid dispersion. Carbohydrate polymer, 130, 26–31.
  • Yang, K.Y., et al., 2013. Silymarin-loaded solid nanoparticles provide excellent hepatic protection: physicochemical characterization and in vivo evaluation. International journal of nanomedicine, 8, 3333–3343.
  • Yousaf, A.M., et al., 2015a. Novel fenofibrate-loaded gelatin microcapsules with enhanced solubility and excellent flowability: preparation and physicochemical characterization. Powder technology, 275, 257–262.
  • Yousaf, A.M., et al., 2015b. Characterization of physicochemical properties of spray-dried solid dispersions loaded with unmodified crystalline fenofibrate. Current pharmaceutical analysis, 11 (2), 139–144.
  • Yousaf, A.M., et al., 2015c. Enhanced oral bioavailability of fenofibrate using polymeric nanoparticulated systems: physicochemical characterization and in vivo investigation. International journal of nanomedicine, 10, 1819–1830.
  • Yousaf, A.M., et al., 2016a. Influence of polyvinylpyrrolidone quantity on the solubility, crystallinity and oral bioavailability of fenofibrate in solvent-evaporated microspheres. Journal of microencapsulation, 33 (4), 365–371.
  • Yousaf, A.M., et al., 2016b. Novel electrosprayed nanospherules for enhanced aqueous solubility and oral bioavailability of poorly water-soluble fenofibrate. International journal of nanomedicine, 11, 213–221.

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