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Letter to the Editor

“A randomized clinical trial of radiation therapy versus thermoradiotherapy in stage IIIB cervical carcinoma” of Yoko Harima et al. (2001): multiple biases and no advantage of hyperthermia

Page 1400 | Received 13 Oct 2017, Accepted 25 Feb 2018, Published online: 13 Sep 2018

References

  • Harima Y, Nagata K, Harima K, et al. A randomized clinical trial of radiation therapy versus thermoradiotherapy in stage IIIB cervical carcinoma. Int J Hyperthermia. 2001;17:97–105.
  • Harima Y, Nagata K, Harima K, et al. A randomized clinical trial of radiation therapy versus thermoradiotherapy in stage IIIB cervical carcinoma. 2001. Int J Hyperthermia. 2009;25:338–43.
  • Harima Y, Sawada S. Hyperthermia classic commentary: 'A randomized clinical trial of radiation therapy versus thermoradiotherapy in stage IIIB cervical carcinoma' by Yoko Harima. Int J Hyperthermia. 2001;17:97–105.
  • Roussakow S. The effectiveness and cost-effectiveness of conventional radiofrequency hyperthermia with concurrent chemo and/or radiotherapy in the treatment of locally advanced cervical cancer: a systematic review of randomized trials with meta-analysis and economical evaluation. PROSPERO 2017:CRD42017072520 Available from http://www.crd.york.ac.uk/PROSPERO/display_record.asp?ID=CRD42017072520. [last accessed 6 Oct 2017].
  • Harima Y, Ohguri T, Imada H, et al. A multicentre randomised clinical trial of chemoradiotherapy plus hyperthermia versus chemoradiotherapy alone in patients with locally advanced cervical cancer. Int J Hyperthermia. 2016;32:801–8.
  • Calculation for Fisher’s exact test. Available from: http://quantpsy.org/fisher/fisher.htm. [last accessed 7 Jul 2017].
  • Calculation for the Chi-square test. Available from: http://quantpsy.org/chisq/chisq.htm. [last accessed 7 Jul 2017].
  • Harima Y, Nagata K, Harima K, et al. (2001): p. 100, “3.1. Treatment response and long-term clinical outcome,” paragraph 2–3.

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