152
Views
0
CrossRef citations to date
0
Altmetric
Research Article

Pre-operative dosing of dexamethasone for the management of children with posterior fossa tumours: are we getting it right?

ORCID Icon, , , , , & show all
Pages 609-612 | Received 19 Jul 2020, Accepted 08 Feb 2022, Published online: 17 Feb 2022

References

  • Wilne S, Collier J, Kennedy C, Koller K, Grundy R, Walker D. Presentation of childhood CNS tumours: a systematic review and meta-analysis. Lancet Oncol 2007;8:685–95.
  • Batchelor TT, Byrne TN. Neurological complications of primary brain tumors. In: Schiff D, Kesari S, Wen PY, eds. Cancer neurology in clinical practice: neurologic complications of cancer and its treatment. Totowa: Humana Press; 2008: 381–396.
  • Bebawy JF. Perioperative steroids for peritumoral intracranial edema: a review of mechanisms, efficacy, and side effects. J Neurosurg Anesth 2012;24:24–28.
  • Pollack IF. Brain tumors in children. N Engl J Med 1994;331:1500–7.
  • Ryan R, Booth S, Price S. Corticosteroid-use in primary and secondary brain tumour patients: a review. J Neuro-Oncol 2012;106:106–109.
  • Alan N, Seicean A, Seicean S, Neuhauser D, Benzel EC, Weil RJ. Preoperative steroid use and the incidence of perioperative complications in patients undergoing craniotomy for definitive resection of a malignant brain tumor. J Clin Neurosci 2015;22:22–29.
  • Ryken TC, Kuo JS, Prabhu RS, Sherman JH, Kalkanis SN, Olson JJ. Congress of neurological surgeons systematic review and evidence-based guidelines on the role of steroids in the treatment of adults with metastatic brain tumors. Neurosurg 2019;84:E189–E191.
  • Ryken TC, McDermott M, Robinson PD, et al. The role of steroids in the management of brain metastases: a systematic review and evidence-based clinical practice guideline. J Neurooncol 2010;96:103–14.
  • Paediatric Formulary Committee. BNF for Children (online) London: BMJ Group, Pharmaceutical Press, and RCP CH Publications [Accessed on [01 November 2021]].
  • Roth P, Wick W, Weller M. Steroids in neurooncology: actions, indications, side-effects. Curr Opin Neurol 2010;23:23–27.
  • Waljee AK, Rogers MAM, Lin P, et al. Short term use of oral corticosteroids and related harms among adults in the United States: population based cohort study. BMJ 2017;j1415: 1415-1423.
  • Dubinski D, Won S-Y, Gessler F, et al. Dexamethasone-induced leukocytosis is associated with poor survival in newly diagnosed glioblastoma. J Neurooncol 2018;137:503–10.
  • Lu VM, Goyal A, Vaughan LS, McDonald KL. The impact of hyperglycemia on survival in glioblastoma: a systematic review and meta-analysis. Clin Neurol Neurosurg 2018; 165–169.
  • Pitter KL, Tamagno I, Alikhanyan K, et al. Corticosteroids compromise survival in glioblastoma. Brain 2016;139:1458–71.
  • Petrelli F, De Stefani A, Ghidini A, et al. Steroids use and survival in patients with glioblastoma multiforme: a pooled analysis. J Neurol 2021;268:440–7.
  • Chang SM, Messersmith H, Ahluwalia M, et al. Anticonvulsant prophylaxis and steroid use in adults with metastatic brain tumors: summary of SNO and ASCO endorsement of the Congress of Neurological Surgeons guidelines. Neuro Oncol 2019;21:424–7.
  • Murayi R, Chittiboina P. Glucocorticoids in the management of peritumoral brain edema: a review of molecular mechanisms. Childs Nerv Syst 2016;32:2293–302.
  • Herting CJ, Chen Z, Maximov V, et al. Tumour-associated macrophage-derived interleukin-1 mediates glioblastoma-associated cerebral oedema. Brain 2019;142:3834–51.
  • Czock D, Keller F, Rasche FM, Häussler U. Pharmacokinetics and pharmacodynamics of systemically administered glucocorticoids. Clin Pharmacokinet 2005;44:61–98.
  • Egerman RS, Pierce WF, 4th, Andersen RN, Umstot ES, Carr TL, Sibai BM. A comparison of the bioavailability of oral and intramuscular dexamethasone in women in late pregnancy. Obstet Gynecol 1997;89:276–80.
  • Hochhaus G, Barth J, al-Fayoumi S, et al. Pharmacokinetics and pharmacodynamics of dexamethasone sodium-m-sulfobenzoate (DS) after intravenous and intramuscular administration: a comparison with dexamethasone phosphate (DP). J Clin Pharmacol 2001;41:425–34.
  • Charles B, Schild P, Steer P, Cartwright D, Donovan T. Pharmacokinetics of dexamethasone following single-dose intravenous administration to extremely low birth weight infants. Dev Pharmacol Ther 1993;20:205–10.
  • Jackson RK, Liebich M, Berry P, et al. Impact of dose and duration of therapy on dexamethasone pharmacokinetics in childhood acute lymphoblastic leukaemia-a report from the UKALL 2011 trial. Eur J Cancer 2019;120:75–85.
  • Richter O, Ern B, Reinhardt D, Becker B. Pharmacokinetics of dexamethasone in children. Pediatr Pharmacol 1983;3:329–37.
  • Dietrich J, Rao K, Pastorino S, Kesari S. Corticosteroids in brain cancer patients: benefits and pitfalls. Expert Rev Clin Pharmacol 2011;4:233–42.
  • Vecht CJ, Hovestadt A, Verbiest HB, van Vliet JJ, van Putten WL. Dose-effect relationship of dexamethasone on Karnofsky performance in metastatic brain tumors: a randomized study of doses of 4, 8, and 16 mg per day. Neurology 1994;44:675–80.
  • Liu D, Ahmet A, Ward L, et al. A practical guide to the monitoring and management of the complications of systemic corticosteroid therapy. Allergy Asthma Clin Immunol 2013;9:30.
  • NICE. Corticosteroids – oral; 2017. Available from: https://cks.nice.org.uk/corticosteroids-oral#!scenario.
  • FDA: Decadron - dexmethasone tablets. Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/011664s063lbl.pdf.
  • Carruthers V, Hill RM, Coulter IC, Cowie CJA, Halliday G, Bailey S. Perioperative corticosteroid use in paediatric neuro-oncology. Childs Nerv Syst 2021;37:3669–71.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.