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Current Eye Research Volume 29, 2004 - Issue 2-3
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Research Article

Feasibility of an antiviral clinical trial requiring cross-country shipment of conjunctival adenovirus cultures and recovery of infectious virus

Eric Romanowski Charles T. Campbell Ophthalmic Microbiology Laboratory, Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
,
Stephen Bartels Bausch & Lomb Pharmaceuticals, Rochester, New York, USA
,
Roger Vogel Clinicor Inc., Austin, Texas, USA
,
Neal Wetherall ViroMed Laboratories Inc., St. Paul, Minnesota, USA
,
Cheryl Hodges-Savola ViroMed Laboratories Inc., St. Paul, Minnesota, USA
,
Regis Kowalski Charles T. Campbell Ophthalmic Microbiology Laboratory, Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
,
Kathleen Yates Charles T. Campbell Ophthalmic Microbiology Laboratory, Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
,
Paul Kinchington Charles T. Campbell Ophthalmic Microbiology Laboratory, Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
&
Y. Gordon Charles T. Campbell Ophthalmic Microbiology Laboratory, Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
 show all
Pages 195-199 | Published online: 02 Jul 2009

References

  • Gordon JS, Aoki K, Kinchington PR. Adenovirus kerato-conjunctivitis. In: Pepose J, Wilhelmus K, Holland G, editors. Ocular Infection and ImmunitySt Louis: Mosby; 1996:877–894.
  • Nagl M, Teuchner B, Pottinger E, Ulmer H, Gottardi W. Tol-erance of N-chlorotaurine, a new antimicrobial agent, in infectious conjunctivitis — a phase II pilot study. Ophthal-mologica.2000;214:111–114.
  • Epstein SP, Pashinsky YY, Winicov I, Asbell PA. Topical cobalt chelate CTC-96 for the treatment of adenovirus conjunctivitis in a rabbit model. IOVS 2003;44:ARVO E-Abstract 4650.
  • Kaneko H, Kato K, Mori S, Shigeta S. Antiviral activity of NMS03 against adenovirus in vitro. Antiviral Res.2001;52:281–288.
  • Kaneko H, Mori S, Shigeta S, Ohno S, Aoki K. [Antiviral effect of sulfated sialyl lipid against a clinical strain of ade-novirus]. Nippon Ganka Gakkai Zasshi.2003;107:196–201.
  • Romanowski EG, Yates KA, Heiry M, Gordon Y.1. Beyond cidofovir the in vitro evaluation of newer potential antivi-ral agents against ocular isolates of adenovirus. Invest Oph-thalmol Vis Sci.2001;42: 5579.
  • Rietveld RP, van Weert HC, ter Riet G, Bindels PJ. Diag-nostic impact of signs and symptoms in acute infectious conjunctivitis: systematic literature search. BM.I.2003;327:789.
  • Hillenkamp J, Reinhard T, Ross RS, Bohringer D, Cartsburg 0, Roggendorf M, De Clercq E, Godehardt E, SundmacherR. Topical treatment of acute adenoviral ker-atoconjunctivitis with 0.2% cidofovir and 1% cyclosporine: a controlled clinical pilot study. Arch Ophthalmol.2001;119: 1487–1491.
  • Hillenkamp J, Reinhard T, Ross RS, Bohringer D, Cartsburg 0, Roggendorf M, De Clercq E, Godehardt E, Sundmacher R. The effects of cidofovir 1% with and without cyclosporin a 1% as a topical treatment of acute adenoviral keratoconjunctivitis: A controlled clinical pilot study. Ophthalmology.2002;109: 845–850.
  • Abad FX, Pinto RM, Bosch A. Survival of enteric viruses on environmental fomites. Appl Environ Microbiol.1994;60:3704–3710.
  • Gordon YJ, Gordon RY, Romanowski E, Araullo-Cruz TP. Prolonged recovery of desiccated adenoviral serotypes 5,8, and 19 from plastic and metal surfaces in vitro. Ophthal-mology.1993;100:1835-1839; discussion 1839–1840.
  • Mahl MC, Sadler C. Virus survival on inanimate surfaces. Can J Microbiol.1975;21:819–823.
  • Nauheim RC, Romanowski EG, Araullo-Cruz T, Kowalski RP, Turgeon PW, Stopak SS, Gordon YJ. Prolonged recov-erability of desiccated adenovirus type 19 from various surfaces. Ophthalmology.1990;97: 1450–1453.
  • Huntoon CJ, House RF, Jr., Smith TF. Recovery of viruses from three transport media incorporated into culturettes. Arch Pathol Lab Med.1981;105:436–437.
  • Johnson FB. Transport of viral specimens. Clin Microbiol Rev.1990;3:120–131.
  • Leibovitz A. A transport medium for diagnostic virology. Proc Soc Exp Biol Med.1969;131:127–130.
  • Rutala WA, Shelton DF, Arbiter D. Comparative sensitivi-ties of viruses to cell cultures and transport media. Am J Clin Pathol.1977;67:397–400.
  • Kowalski RP, Karenchak LM, Romanowski EG,, CommunityOphthalmologists of Pittsburgh, Pennsylvania. Evaluation of the shell vial technique for detection of ocular adenovirus. Ophthalmology.1999;106:1324–1327.
  • Wilhelmus KR. Interventions for herpes simplex virus epithelial keratitis. Cochrane Database Syst Rev.2003: CD002898.
  • Hoh HB, Hurley C, Claoue C et al.Randomised trial of ganciclovir and acyclovir in the treatment of herpes simplex dendritic keratitis: a multicentre study. Br J Ophthalmol.1996;80:140–143.
  • Kowalski RP, Romanowski EG, Waikhom B, Gordon YJ. The survival of adenovirus in multidose bottles of topical fluorescein. Am J Ophthalmol.1998;126:835–836.
  • Roba LA, Kowalski RP, Gordon AT, Romanowski EG, Gordon YJ. Adenoviral ocular isolates demonstrate serotype-dependent differences in in vitro infectivity titers and clinical course. Cornea.1995;14:388–393.
  • Aoki K, Tagawa Y. A twenty-one year surveillance of ade-noviral conjunctivitis in Sapporo, Japan. Int Ophthalmol Clin.2002;42:49–54.
  • Erdman DD, Xu W, Gerber SI, Gray GC, Schnurr D, Kajon AE, Anderson U. Molecular epidemiology of adenovirus type 7 in the United States, 1966–2000. Emerg Infect Dis.2002;8: 269–277.
  • Guo DF, Shinagawa M, Aoki K, Sawada H, Itakura S, Sato G. Genome typing of adenovirus strains isolated from conjunctivitis in Japan, Australia, and the Philippines. Microbiol Immunol.1988;32:1107–1118.
  • Imperiale MJ, Kochanek S. Adenovirus vectors: Biology, design, and production. Curr Top Microbiol Immunol.2004;273:335–357.
  • Palmer DH, Mautner V, Kerr DJ. Clinical experience with adenovirus in cancer therapy. Curr Opin Mol Ther.2002;4:423–434.

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