REFERENCES
- Klein R, Peto T, Bird A, et al. The epidemiology of age-related macular degeneration. Am J Ophthalmol. 2004; 137: 486–495
- de Jong P T. Age-related macular degeneration. N Engl J Med. 2006; 355: 1474–1485
- Tuo J, Bojanowski C M, Zhou M, et al. Murine ccl2/cx3cr1 deficiency results in retinal lesions mimicking human age-related macular degeneration. Invest Ophthalmol Vis Sci. 2007; 48: 3827–3836
- Strauss O. The retinal pigment epithelium in visual function. Physiol Rev. 2005; 85: 845–881
- Fine S L, Berger J W, Maguire M G, et al. Age-related macular degeneration. N Engl J Med. 2000; 342: 483–492
- De S, Rabin D M, Salero E, et al. Human retinal pigment epithelium cell changes and expression of alphaB-crystallin: A biomarker for retinal pigment epithelium cell change in age-related macular degeneration. Arch Ophthalmol. 2007; 125: 641–645
- Dunn K C, Aotaki-Keen A E, Putkey F R, et al. ARPE-19, a human retinal pigment epithelial cell line with differentiated properties. Exp Eye Res. 1996; 62: 155–169
- McLaren M J, Sasabe T, Li C Y, et al. Spontaneously arising immortal cell line of rat retinal pigmented epithelial cells. Exp Cell Res. 1993; 204: 311–320
- Macario A J, Conway de M E. Sick chaperones, cellular stress, and disease. N Engl J Med. 2005; 353: 1489–1501
- Meriin A B, Sherman M Y. Role of molecular chaperones in neurodegenerative disorders. Int J Hyperthermia. 2005; 21: 403–419
- Sauer T, Patel M, Chan C C, et al. Unfolding the therapeutic potential of chemical chaperones for age-related macular degeneration. Expert Review of Ophthalmology. 2008; 3: 29–42
- Hermann V M, Cutfield J F, Hubbard M J. Biophysical characterization of ERp29. Evidence for a key structural role of cysteine 125. J Biol Chem. 2005; 280: 13529–13537
- Demmer J, Zhou C, Hubbard M J. Molecular cloning of ERp29, a novel and widely expressed resident of the endoplasmic reticulum. FEBS Lett. 1997; 402: 145–150
- Mkrtchian S, Sandalova T. ERp29, an unusual redox-inactive member of the thioredoxin family. Antioxid Redox Signal. 2006; 8: 325–337
- Shnyder S D, Hubbard M J. ERp29 is a ubiquitous resident of the endoplasmic reticulum with a distinct role in secretory protein production. J Histochem Cytochem. 2002; 50: 557–566
- Beatty S, Koh H, Phil M, et al. The role of oxidative stress in the pathogenesis of age-related macular degeneration. Surv Ophthalmol. 2000; 45: 115–134
- Finkel T, Holbrook N J. Oxidants, oxidative stress, and the biology of aging. Nature. 2000; 408: 239–247
- Wang N, Koutz C A, Anderson R E. A method for the isolation of retinal pigment epithelial cells from adult rats. Invest Ophthalmol Vis Sci. 1993; 34: 101–107
- Mayerson P L, Hall M O, Clark V, et al. An improved method for isolation and culture of rat retinal pigment epithelial cells. Invest Ophthalmol Vis Sci. 1985; 26: 1599–1609
- Nandrot E F, Kim Y, Brodie S E, et al. Loss of synchronized retinal phagocytosis and age-related blindness in mice lacking alphavbeta5 integrin. J Exp Med. 2004; 200: 1539–1545
- Maminishkis A, Chen S, Jalickee S, et al. Confluent monolayers of cultured human fetal retinal pigment epithelium exhibit morphology and physiology of native tissue. Invest Ophthalmol Vis Sci. 2006; 47: 3612–3624
- Rakoczy P, Yu M, Nusinowitz S, et al. Mouse models of age-related macular degeneration. Exp Eye Res. 2006; 86: 741–752
- Marmorstein A D, Marmorstein L Y. The challenge of modeling macular degeneration in mice. Trends Genet. 2007; 23: 225–231
- Schlunck G, Martin G, Agostini H T, et al. Cultivation of retinal pigment epithelial cells from human choroidal neovascular membranes in age related macular degeneration. Exp Eye Res. 2002; 74: 571–576
- Ethen C M, Reilly C, Feng X, et al. The proteome of central and peripheral retina with progression of age-related macular degeneration. Invest Ophthalmol Vis Sci. 2006; 47: 2280–2290
- Zheng J, Liu X, Yan X, et al. Purification and structural characterization of human ERp29. Protein Pept Lett. 2006; 13: 753–759
- Suzuki M, Kamei M, Itabe H, et al. Oxidized phospholipids in the macula increase with age and in eyes with age-related macular degeneration. Mol Vis. 2007; 13: 772–778
- Engelmann K, Valtink M. RPE cell cultivation. Graefes Arch Clin Exp Ophthalmol. 2004; 242: 65–67