REFERENCES
- WuDunn D. Genetic basis of glaucoma. Curr Opin Ophthalmol 2002; 30: 55–60
- Babizhayev M A, Bunin A. Lipid peroxidation in open-angle glaucoma. Acta Ophthalmol (Copenh) 1989; 67: 371–377
- Ohia S E, Opere C A, Leday A M. Pharmacological consequences of oxidative stress in ocular tissues. Mutat Res 2005; 579: 22–36
- Muller A, Pietri S, Villain M, Frejaville C, Bonne C, Culcas M. Free radicals in rabbit retina under ocular hyperpressure and functional consequences. Exp Eye Res 1997; 64: 637–643
- Tezel G. Oxidative stress in glaucomatous neurodegeneration: Mechanisms and consequences. Prog Retin Eye Res 2006; 25: 490–513
- Ko M L, Peng P H, Ma M C, Ritch R, Chen C F. Dynamic changes in reactive oxygen species and antioxidant levels in retinas in experimental glaucoma. Free Radic Biol Med 2005; 39: 365–373
- The Advanced Glaucoma Intervention Study (AGIS): 7. The relationship between control of intraocular pressure and visual field deterioration. The AGIS Investigators. Am J Ophthalmol 2000; 130: 429–440
- Beit-Yannai E, Trembovler V, Solomon A S. Decrease in reducing power of aqueous humor originating from glaucomatous rabbits. Eye 2007; 21: 658–664
- McKee M, Scavone C, Nathanson J A. Nitric oxide, cGMP, and hormone regulation of active sodium transport. Proc Natl Acad Sci USA 1994; 91: 12056–12060
- Nathanson J A, McKee M. Identification of an extensive system of nitric oxide-producing cells in the ciliary muscle and outflow pathway of the human eye. Invest Ophthalmol Vis Sci 1995; 36: 1765–1773
- Nuzzi R, Finazzo C, Boles Carenini B. Nitric oxide synthetase distribution in the sclerocorneal trabecular meshwork in chronic simple glaucoma patients. Acta Ophthalmol Scand Suppl 1997; 224: 9
- Guyton K Z, Liu Y, Gorospe M, Xu Q, Holbrook N J. Activation of mitogen-activated protein kinase by H2O2. Role in cell survival following oxidant injury. J Biol Chem 1996; 271: 4138–4142
- Klotz L O, Pellieux C, Briviba K, Pierlot C, Aubry J M, Sies H. Mitogen-activated protein kinase (p38-, JNK-, ERK-) activation pattern induced by extracellular and intracellular singlet oxygen and UVA. Eur J Biochem 1999; 260: 917–922
- Posen Y, Kalchenko V, Seger R, Brandis A, Scherz A, Salomon Y. Manipulation of redox signaling in mammalian cells enabled by controlled photogeneration of reactive oxygen species. J Cell Sci 2005; 118: 1957–1969
- Kim B Y, Han M J, Chung A S. Effects of reactive oxygen species on proliferation of Chinese hamster lung fibroblast (V79) cells. Free Radic Biol Med 2001; 30: 686–698
- Torres M. Mitogen-activated protein kinase pathways in redox signaling. Front Biosci 2003; 8: d369–391
- Li D Q, Luo L, Chen Z, Kim H S, Song X J, Pflugfelder S C. JNK and ERK MAP kinases mediate induction of IL-1beta, TNF-alpha, and IL-8 following hyperosmolar stress in human limbal epithelial cells. Exp Eye Res 2006; 82: 588–596
- Hashimoto K, Parker A, Malone P, Gabelt B T, Rasmussen C, Kaufman P S, Hernandez M R. Long-term activation of c-Fos and c-Jun in optic nerve head astrocytes in experimental ocular hypertension in monkeys and after exposure to elevated pressure in vitro. Brain Res 2005; 1054: 103–115
- Alexander J P, Acott T S. Involvement of the Erk-MAP kinase pathway in TNFalpha regulation of trabecular matrix metalloproteinases and TIMPs. Invest Ophthalmol Vis Sci 2003; 44: 164–169
- Tumminia S J, Mitton K P, Arora J, Zelenka P, Epstein D L, Russell P. Mechanical stretch alters the actin cytoskeletal network and signal transduction in human trabecular meshwork cells. Invest Ophthalmol Vis Sci 1998; 39: 1361–1371
- Adler V, Yin Z, Tew K D, Ronai Z. Role of redox potential and reactive oxygen species in stress signaling. Oncogene 1999; 18: 6104–6111
- Knepper P A, Miller A M, Choi J, Wertz R D, Nolan M J, Goossens W, Whitmer S, Yue B Y, Ritch R, Liebmann J M, Allingham R R, Samples J R. Hypophosphorylation of aqueous humor sCD44 and primary open-angle glaucoma. Invest Ophthalmol Vis Sci 2005; 46: 2829–2837
- Beit-Yannai E, Shmulevich A. Does the aqueous humor have a role in mitogen-activated protein kinase (MAPK) intracellular signaling in Glaucoma?. Med Hypotheses 2007; 68: 299–302
- Moreno M C, Marcos H J, Oscar Croxatto J, Sande P H, Campanelli J, Jaliffa C O, Benozzi J, Rosenstein R E. A new experimental model of glaucoma in rats through intracameral injections of hyaluronic acid. Exp Eye Res 2005; 81: 71–80
- Benozzi J, Nahum L P, Campanelli J L, Rosenstein R E. Effect of hyaluronic acid on intraocular pressure in rats. Invest Ophthalmol Vis Sci 2002; 43: 2196–2200
- Moore C G, Epley D, Milne S T, Morrison J C. Long-term non-invasive measurement of intraocular pressure in the rat eye. Curr Eye Res 1995; 8: 711–717
- Iyengar L, Patkunanathan B, Lynch O T, McAvoy J W, Rasko J E, Lovicu F J. Aqueous humour- and growth factor-induced lens cell proliferation is dependent on MAPK/ERK1/2 and Akt/PI3-K signalling. Exp Eye Res 2006; 83: 667–678
- Zhang X, Schroeder A, Callahan E M, Coyle B M, Wang N, Erickson K A, Schuman J S, Fini M E. Constitutive signalling pathway activity in trabecular meshwork cells from glaucomatous eyes. Exp Eye Res 2006; 82: 968–973
- Zhou X, Li F, Kong L, Tomita H, Li C, Cao W. Involvement of inflammation, degradation, and apoptosis in a mouse model of glaucoma. J Biol Chem 2005; 280: 31240–31248
- Zhang X, Li A, Ge J, Reigada D, Laties A M, Mitchell C H. Acute increase of intraocular pressure releases ATP into the anterior chamber. Exp Eye Res 2007; 85: 637–643
- Yung Y, Yao Z, Hanoch T, Seger R. ERK1b, a 46-kDa ERK isoform that is differentially regulated by MEK. J Biol Chem 2000; 275: 15799–15808
- Kinkl N, Sahel J, Hicks D. Alternate FGF2-ERK1/2 signaling pathways in retinal photoreceptor and glial cells in vitro. J Biol Chem 2001; 276: 43871–43878
- Kolch W. Meaningful relationships: The regulation of the Ras/Raf/MEK/ERK pathway by protein interactions. Biochem J 2000; 351: 289–305, (Pt 2)
- Jelinek T, Catling A D, Reuter C W, Moodie S A, Wolfman A, Weber M J. RAS and RAF-1 form a signalling complex with MEK-1 but not MEK-2. Mol Cell Biol 1994; 14: 8212–8218
- Mielke K, Damm A, Yang D D, Herdegen T. Selective expression of JNK isoforms and stress-specific JNK activity in different neural cell lines. Brain Res Mol Brain Res 2000; 75: 128–137
- Sabapathy K, Hochedlinger K, Nam S Y, Bauer A, Karin M, Wagner E F. Distinct roles for JNK1 and JNK2 in regulating JNK activity and c-Jun-dependent cell proliferation. Mol Cell 2004; 15: 713–725
- Tuncman G, Hirosumi J, Solinas G, Chang L, Karin M, Hotamisligil G S. Functional in vivo interactions between JNK1 and JNK2 isoforms in obesity and insulin resistance. Proc Natl Acad Sci USA 2006; 103: 10741–10746
- Takatori A, Geh E, Chen L, Zhang L, Meller J, Xia Y. Differential transmission of MEKK1 morphogenetic signals by JNK1 and JNK2. Development 2008; 135: 23–32
- Karin M. The regulation of AP-1 activity by mitogen-activated protein kinases. J Biol Chem 1995; 270: 16483–16486
- Whitmarsh A J, Davis R J. Transcription factor AP-1 regulation by mitogen-activated protein kinase signal transduction pathways. J Mol Med 1996; 74: 589–607
- Kamata H, Hirata H. Redox regulation of cellular signalling. Cell Signal 1999; 11: 1–14
- Wilhelm D, Bender K, Knebel A, Angel P. The level of intracellular glutathione is a key regulator for the induction of stress-activated signal transduction pathways including Jun N-terminal protein kinases and p38 kinase by alkylating agents. Mol Cell Biol 1997; 17: 4792–4800
- Kurysheva N I, Vinetskaia M I, Erichev V P, Demchuk M L, Kuryshev S I. Contribution of free-radical reactions of chamber humor to the development of primary open-angle glaucoma. Vestn Oftalmol 1996; 112: 3–5
- Koliakos G G, Befani C D, Mikropoulos D, Ziakas N G, Konstas A G. Prooxidant-antioxidant balance, peroxide and catalase activity in the aqueous humor and serum of patients with exfoliation syndrome or exfoliative glaucoma. Graefes Arch Clin Exp Ophthalmol 2008; 246: 1477–1483
- Kotikoski H, Moilanen E, Vapaatalo H, Aine E. Biochemical markers of the L-arginine-nitric oxide pathway in the aqueous humor in glaucoma patients. Acta Ophthalmol Scand 2002; 80: 191–195
- Ferreira S M, Lerner S F, Brunzini R, Evelson P A, Llesuy S F. Oxidative stress markers in aqueous humor of glaucoma patients. Am J Ophthalmol 2004; 137: 62–69