Nuclear and Mitochondrial DNA of Age-Related Cataract Patients Are Susceptible to Oxidative Damage

References

• Wormstone IM, Collison, DJ, Hansom SP, Duncan G. A focus on the human lens in vitro. Environ Toxicol Pharmacol 2006;21:215–221.
   PubMed Web of Science ®Google Scholar
• The World Health Organisation (WHO). Prevention of Blindness and Visual Impairment: Priority eye diseases: Cataract. 2015. Accessed Sept 2015. Available from: http://www.who.int/blindness/causes/priority/en/index1.html.
   Google Scholar
• Asbell PA, Dualan I, Mindel J, Brocks D, Ahmad M, Epstein S. Age-related cataract. Lancet 2005;365:599–609.
   PubMed Web of Science ®Google Scholar
• Zetterberg M, Celojevic D. Gender and cataract-the role of estrogen. Curr Eye Res 2015;40:176–190.
   PubMed Web of Science ®Google Scholar
• Olofsson EM, Marklund SL, Behndig A. Enhanced age-related cataract in copper-zinc superoxide dismutase null mice. Clin Experiment Ophthalmol 2012;40:813–820.
   PubMed Web of Science ®Google Scholar
• Brennan LA, Kantorow M. Mitochondrial function and redox control in the aging eye: role of MsrA and other repair systems in cataract and macular degenerations. Exp Eye Res 2009;88:195–203.
   PubMed Web of Science ®Google Scholar
• Vinson JA. Oxidative stress in cataracts. Pathophysiology. 2006;13:151–162.
   PubMedGoogle Scholar
• Bohr VA. Repair of oxidative DNA damage in nuclear and mitochondrial DNA, and some changes with aging in mammalian cells. Free Radic Biol Med 2002;32:804–812.
   PubMed Web of Science ®Google Scholar
• Hasty P. The impact of DNA damage, genetic mutation and cellular responses on cancer prevention, longevity and aging: observations in human and mice. Mech Aging Dev 2005;126:71–77.
   PubMed Web of Science ®Google Scholar
• Jang YC, Van Remmen H. The mitochondrial theory of aging: insight from transgenic and knockout mouse models. Exp Gerontol 2009;44:256–260.
   PubMed Web of Science ®Google Scholar
• Gorbunova V, Seluanov A, Mao Z, Hine C. Changes in DNA repair during aging. Nucleic Acids Res 2007;35:7466–7474.
   PubMed Web of Science ®Google Scholar
• Kleiman NJ, Spector A. DNA single strand breaks in human lens epithelial cells from patients with cataract. Curr Eye Res 1993;12:423–431.
   PubMed Web of Science ®Google Scholar
• Sorte K, Sune P, Bhake A, Shivkumar VB, Gangane N, Basak A. Quantitative assessment of DNA damage directly in lens epithelial cells from senile cataract patients. Mol Vis 2011;17:1–6.
   PubMed Web of Science ®Google Scholar
• Ates O, Alp HH, Kocer I, Baykal O, Salman IA. Oxidative DNA damage in patients with cataract. Acta Ophthalmol 2010;88:891–895.
   PubMed Web of Science ®Google Scholar
• Chang D, Zhang X, Rong S, Sha Q, Liu P, Han T, Pan H. Serum antioxidative enzymes levels and oxidative stress products in age-related cataract patients. Oxid Med Cell Longev 2013;2013:587826.
   PubMed Web of Science ®Google Scholar
• Zhang J, Wu J, Yang L, Zhu R, Yang M, Qin B, et al. DNA damage in lens epithelial cells and peripheral lymphocytes from age-related cataract patients. Ophthalmic Res 2014;51:124–128.
   PubMed Web of Science ®Google Scholar
• Aebi H, Methods of enzymatic analysis. In: Bergmeyer HU, ed. Catalase, Vol. 2, New York: Academic Press. 1974;673–684.
   Google Scholar
• Erol Ö, Arda N, Erdem G. Phenols of virgin olive oil protects nuclear DNA against oxidative damage in HeLa cells. Food Chem Toxicol 2012;50:3475–3479.
   PubMed Web of Science ®Google Scholar
• Kovalenko OA, Santos JH. Analysis of oxidative damage by gene-specific quantitative PCR. Curr Protoc Hum Genet 2009;62:19.1.1–19.1.13.
   Google Scholar
• Dizdaroğlu M, Jaruga P, Birincioğlu M, Rodriguez H. Free radical-induced damage to DNA: mechanisms and measurement. Free Radical Bio Med 2002;32:1102–1115.
   PubMed Web of Science ®Google Scholar
• Furda A, Santos JH, Meyer JN, Van Houten B. Quantitative PCR-based measurement of nuclear and mitochondrial DNA damage and repair in mammalian cells. Methods Mol Biol 2014;1105:419–437.
   PubMedGoogle Scholar
• Shiels A, Hejtmancik JF. Genetics of human cataract. Clin Genet 2013;84:120–127.
   PubMed Web of Science ®Google Scholar
• Varma SD, Kovtun S, Hegde KR. Role of ultraviolet irradiation and oxidative stress in cataract formation-medical prevention by nutritional antioxidants and metabolic agonists. Eye Contact Lens 2011;37:233–245.
   PubMed Web of Science ®Google Scholar
• Li WC, Kuszak JR, Dunn K, Wang RR, Ma W, Wang GM, et al. Lens epithelial cell apoptosis appears to be a common cellular basis for non congenital cataract development in humans and animals. J Cell Biol 1995;130:169–181.
   PubMed Web of Science ®Google Scholar
• Garinis GA, Van der Horst GT, Vijg J, Hoeijmakers JH. DNA dammath and ageing: new-age ideas for an age-old problem. Nat Cell Biol 2008;10:1241–1247.
   PubMed Web of Science ®Google Scholar
• Michael R, Bron AJ. The ageing lens and cataract: a model of normal and pathological ageing. Philos Trans R Soc Lond B Biol Sci 2011;366:1278–1292.
   PubMed Web of Science ®Google Scholar
• Spector A. Oxidative stress-induced cataract: mechanism of action. FASEB J 1995;9:1173–182.
   PubMed Web of Science ®Google Scholar
• Vîrgolici B, Stoian I, Muscurel C, Mărăcine M, Popescu L, Moraru C, Dinu V. Systemic redox modifications in senile cataract. Rom J Intern Med 2009;47:279–287.
   PubMedGoogle Scholar
• Wei YH, Lee HC. Oxidative stress, mitochondrial DNA mutation, and impairment of antioxidant enzymes in aging. Exp Biol Med 2002;227:671–682.
   PubMed Web of Science ®Google Scholar
• Liang FQ, Godley BF. Oxidative stress-induced mitochondrial DNA damage in human retinal pigment epithelial cells: a possible mechanism for RPE aging and age-related macular degeneration. Exp Eye Res 2003;76:397–403.
   PubMed Web of Science ®Google Scholar
• Yakes FM, Van Houten B. Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress. Proc Natl Acad Sci USA 1997;94:514–519.
   PubMed Web of Science ®Google Scholar
• Liu P, Demple B, DNA repair in mammalian mitochondria: much more than we thought? Environ Mol Mutagen 2010;51:417–426.
   PubMed Web of Science ®Google Scholar
• Laberge RM, Adler D, DeMaria M, Mechtouf N, Teachenor R, Cardin GB, Desprez PY, Campisi J, Rodier F. Mitochondrial DNA damage induces apoptosis in senescent cells. Cell Death Dis 2013;18:e727.
   Web of Science ®Google Scholar
• Cline SD. Mitochondrial DNA damage and its consequences for mitochondrial gene expression. Biochim Biophys Acta 2012;1819:979–991.
   PubMed Web of Science ®Google Scholar
• Hawse JR, Hejtmancik JF, Horwitz J, Kantorow M. Identification and functional clustering of global gene expression differences between age-related cataract and clear human lenses and aged human lenses. Exp Eye Res 2004;79:935–940.
   PubMed Web of Science ®Google Scholar
• Mesa R, Bassnett S. UV-B-induced DNA damage and repair in the mouse lens. Invest Ophthalmol Vis Sci 2013;54:6789–6797.
   PubMed Web of Science ®Google Scholar
• Andley UP, Song Z, Mitchell DL. DNA repair and survival in human lens epithelial cells with extended lifespan. Curr Eye Res 1999;18:224–230.
   PubMed Web of Science ®Google Scholar
• Torbergsen AC, Collins AR. Recovery of human lymphocytes from oxidative DNA damage; the apparent enhancement of DNA repair by carotenoids is probably simply an antioxidant effect. Eur J Nutr 2000;39:80–85.
   PubMed Web of Science ®Google Scholar