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Cornea & Ocular Surface

Cultivation of Human Oral Mucosal Explants on Contact Lenses

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Pages 1094-1099 | Received 22 Jul 2016, Accepted 03 Jan 2017, Published online: 24 Mar 2017

References

  • Takacs L, Toth E, Berta A, Vereb G. Stem cells of the adult cornea: from cytometric markers to therapeutic applications. Cytometry A 2009;75:54–66.
  • Tseng SC, Chen SY, Shen YC, Chen WL, Hu FR. Critical appraisal of ex vivo expansion of human limbal epithelial stem cells. Curr Mol Med 2010;10:841–850.
  • Health Quality Ontario. Limbal stem cell transplantation: an evidence-based analysis. Ont Health Technol Assess Ser 2008;8:1–58.
  • Utheim TP. Concise review: transplantation of cultured oral mucosal epithelial cells for treating limbal stem cell deficiency-current status and future perspectives. Stem Cells 2015;33:1685–1695.
  • Burillon C, Huot L, Justin V, et al. Cultured autologous oral mucosal epithelial cell sheet (CAOMECS) transplantation for the treatment of corneal limbal epithelial stem cell deficiency. Invest Ophthalmol Vis Sci 2012;53:1325–1331.
  • Hirayama M, Satake Y, Higa K, Yamaguchi T, Shimazaki J. Transplantation of cultivated oral mucosal epithelium prepared in fibrin-coated culture dishes. Invest Ophthalmol Vis Sci 2012;53:1602–1609.
  • Nakamura T, Takeda K, Inatomi T, Sotozono C, Kinoshita S. Long-term results of autologous cultivated oral mucosal epithelial transplantation in the scar phase of severe ocular surface disorders. Br J Ophthalmol 2011;95:942–946.
  • Nishida K, Yamato M, Hayashida Y, et al. Functional bioengineered corneal epithelial sheet grafts from corneal stem cells expanded ex vivo on a temperature-responsive cell culture surface. Transplantation 2004;77:379–385.
  • Ricardo JR, Cristovam PC, Filho PA, et al. Transplantation of conjunctival epithelial cells cultivated ex vivo in patients with total limbal stem cell deficiency. Cornea 2013;32:221–228.
  • Satake Y, Higa K, Tsubota K, Shimazaki J. Long-term outcome of cultivated oral mucosal epithelial sheet transplantation in treatment of total limbal stem cell deficiency. Ophthalmology 2011;118:1524–1530.
  • Tsai RJ, Li LM, Chen JK. Reconstruction of damaged corneas by transplantation of autologous limbal epithelial cells. N Engl J Med 2000;343:86–93.
  • Shortt AJ, Secker GA, Notara MD, et al. Transplantation of ex vivo cultured limbal epithelial stem cells: a review of techniques and clinical results. Surv Ophthalmol 2007;52:483–502.
  • Pellegrini G, Rama P, Di Rocco A, Panaras A, De Luca M. Concise review: hurdles in a successful example of limbal stem cell-based regenerative medicine. Stem Cells 2014;32:26–34.
  • Mariappan I, Maddileti S, Savy S, et al. In vitro culture and expansion of human limbal epithelial cells. Nat Protoc 2010;5:1470–1479.
  • Basu S, Fernandez MM, Das S, Gaddipati S, Vemuganti GK, Sangwan VS. Clinical outcomes of xeno-free allogeneic cultivated limbal epithelial transplantation for bilateral limbal stem cell deficiency. Br J Ophthalmol 2012;96:1504–1509.
  • Kolli S, Ahmad S, Mudhar HS, Meeny A, Lako M, Figueiredo FC. Successful application of ex vivo expanded human autologous oral mucosal epithelium for the treatment of total bilateral limbal stem cell deficiency. Stem Cells 2014;32:2135–2146.
  • Zakaria N, Possemiers T, Dhubhghaill SN, et al. Results of a phase I/II clinical trial: standardized, non-xenogenic, cultivated limbal stem cell transplantation. J Transl Med 2014;12:58.
  • Madhira SL, Vemuganti G, Bhaduri A, Gaddipati S, Sangwan VS, Ghanekar Y. Culture and characterization of oral mucosal epithelial cells on human amniotic membrane for ocular surface reconstruction. Mol Vis 2008;14:189–196.
  • Pellegrini G, Traverso CE, Franzi AT, Zingirian M, Cancedda R, De Luca M. Long-term restoration of damaged corneal surfaces with autologous cultivated corneal epithelium. Lancet 1997;349:990–993.
  • Rama P, Bonini S, Lambiase A, et al. Autologous fibrin-cultured limbal stem cells permanently restore the corneal surface of patients with total limbal stem cell deficiency. Transplantation 2001;72:1478–1485.
  • Nishida K, Yamato M, Hayashida Y, et al. Corneal reconstruction with tissue-engineered cell sheets composed of autologous oral mucosal epithelium. N Engl J Med 2004;351:1187–1196.
  • Di Girolamo N, Bosch M, Zamora K, Coroneo MT, Wakefield D, Watson SL. A contact lens-based technique for expansion and transplantation of autologous epithelial progenitors for ocular surface reconstruction. Transplantation 2009;87:1571–1578.
  • Bobba S, Chow S, Watson S, Di Girolamo N. Clinical outcomes of xeno-free expansion and transplantation of autologous ocular surface epithelial stem cells via contact lens delivery: a prospective case series. Stem Cell Res Ther 2015;6:23.
  • Toth E, Beyer D, Zsebik B, Vereb G, Takacs L. Limbal and conjunctival epithelial cell cultivation on contact lenses-different affixing techniques and the effect of feeder cells. Eye Contact Lens 2016.
  • Dobrowolski D, Orzechowska-Wylegala B, Wowra B, et al. Cultivated oral mucosa epithelium in ocular surface reconstruction in aniridia patients. Biomed Res Int 2015;2015:281870.
  • Sotozono C, Inatomi T, Nakamura T, et al. Cultivated oral mucosal epithelial transplantation for persistent epithelial defect in severe ocular surface diseases with acute inflammatory activity. Acta Ophthalmol 2014;92:e447–e453.
  • Bjorkblom B, Eidet JR, Utheim TP, Ulltveit-Moe HF, Raeder S. Xenobiotic- and Serum-free culture of oral mucosal epithelial cells on contact lenses. Curr Eye Res 2016;41:20–27.
  • Echevarria TJ, Chow S, Watson S, Wakefield D, Di Girolamo N. Vitronectin: a matrix support factor for human limbal epithelial progenitor cells. Invest Ophthalmol Vis Sci 2011;52:8138–8147.
  • Lindroos B, Aho KL, Kuokkanen H, et al. Differential gene expression in adipose stem cells cultured in allogeneic human serum versus fetal bovine serum. Tissue Eng Part A 2010;16:2281–2294.
  • Thanos S, Gatzioufas Z, Schallenberg M, Konig S, Meyer-Rusenberg HW, Busse H. Clinical transplantation of individualized recipient serum-adapted cornea reduces the risk of graft rejection after keratoplasty. Cell Transplant 2013;22:477–491.
  • Bardag-Gorce F, Oliva J, Wood A, et al. Carrier-free cultured autologous oral mucosa epithelial cell sheet (CAOMECS) for corneal epithelium reconstruction: a histological study. Ocul Surf 2015;13:150–163.
  • Kim JH, Chun YS, Lee SH, et al. Ocular surface reconstruction with autologous nasal mucosa in cicatricial ocular surface disease. Am J Ophthalmol 2010;149:45–53.
  • Nakamura T, Kinoshita S. Ocular surface reconstruction using cultivated mucosal epithelial stem cells. Cornea 2003;22:S75–S80.
  • Sheth R, Neale MH, Shortt AJ, Massie I, Vernon AJ, Daniels JT. Culture and characterization of oral mucosal epithelial cells on a fibrin gel for ocular surface reconstruction. Curr Eye Res 2015;40:1077–1087.
  • Rama P, Matuska S, Paganoni G, Spinelli A, De Luca M, Pellegrini G. Limbal stem-cell therapy and long-term corneal regeneration. N Engl J Med 2010;363:147–155.

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