Retinal Structure in Pre-Clinical Age-Related Macular Degeneration

References

• Fritsche LG, Igl W, Bailey JN, Grassmann F, Sengupta S, Bragg-Gresham JL, et al. A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants. Nat Genet. 2016;48(2):134–43.
   PubMed Web of Science ®Google Scholar
• Gorin MB, Weeks DE, Baron RV, Conley YP, Ortube MC, Nusinowitz S. Endophenotypes for age-related macular degeneration: extending our reach into the preclinical stages of disease. J Clin Med. 2014;3(4):1335–56.
   PubMedGoogle Scholar
• Fritsche LG, Chen W, Schu M, Yaspan BL, Yu Y, Thorleifsson G, et al. Seven new loci associated with age-related macular degeneration. Nat Genet. 2013;45(4):433–9, 9e1–2.
   PubMed Web of Science ®Google Scholar
• Schmitz-Valckenberg S, Bultmann S, Dreyhaupt J, Bindewald A, Holz FG, Rohrschneider K. Fundus autofluorescence and fundus perimetry in the junctional zone of geographic atrophy in patients with age-related macular degeneration. Invest Ophthalmol Vis Sci. 2004;45(12):4470–76.
   PubMed Web of Science ®Google Scholar
• Scholl HP, Bellmann C, Dandekar SS, Bird AC, Fitzke FW. Photopic and scotopic fine matrix mapping of retinal areas of increased fundus autofluorescence in patients with age-related maculopathy. Invest Ophthalmol Vis Sci. 2004;45(2):574–83.
   PubMed Web of Science ®Google Scholar
• Steinberg JS, Fitzke FW, Fimmers R, Fleckenstein M, Holz FG, Schmitz-Valckenberg S. Scotopic and photopic microperimetry in patients with reticular drusen and age-related macular degeneration. JAMA Ophthalmol. 2015;133(6):690–97.
   PubMed Web of Science ®Google Scholar
• Cideciyan AV, Swider M, Aleman TS, Feuer WJ, Schwartz SB, Russell RC, et al. Macular function in macular degenerations: repeatability of microperimetry as a potential outcome measure for ABCA4-associated retinopathy trials. Invest Ophthalmol Vis Sci. 2012;53(2):841–52.
   PubMed Web of Science ®Google Scholar
• Ferris FL, 3rd, Wilkinson CP, Bird A, Chakravarthy U, Chew E, Csaky K, et al. Clinical classification of age-related macular degeneration. Ophthalmology. 2013;120(4):844–51.
   PubMed Web of Science ®Google Scholar
• Mukhopadhyay N, Almasy L, Schroeder M, Mulvihill WP, Weeks DE. Mega2: data-handling for facilitating genetic linkage and association analyses. Bioinformatics. 2005;21(10):2556–57.
   PubMed Web of Science ®Google Scholar
• Renteria ME, Cortes A, Medland SE. Using PLINK for Genome-Wide Association Studies (GWAS) and data analysis. Methods Mol Biol. 2013;1019:193–213.
   PubMedGoogle Scholar
• Chen C, Wu L, Jiang F, Liang J, Wu DZ. Scotopic sensitivity of central retina in early age-related macular degeneration. Yan Ke Xue Bao. 2003;19(1):15–19.
   PubMedGoogle Scholar
• Dimitrov PN, Robman LD, Varsamidis M, Aung KZ, Makeyeva G, Busija L, et al. Relationship between clinical macular changes and retinal function in age-related macular degeneration. Invest Ophthalmol Vis Sci. 2012;53(9):5213–20.
   PubMed Web of Science ®Google Scholar
• Dimitrov PN, Robman LD, Varsamidis M, Aung KZ, Makeyeva GA, Guymer RH, et al. Visual function tests as potential biomarkers in age-related macular degeneration. Invest Ophthalmol Vis Sci. 2011;52(13):9457–69.
   PubMed Web of Science ®Google Scholar
• Haimovici R, Owens SL, Fitzke FW, Bird AC. Dark adaptation in age-related macular degeneration: relationship to the fellow eye. Graefe’s Arch Clin Exp Ophthalmol. 2002;240(2):90–95.
   PubMed Web of Science ®Google Scholar
• Jackson GR, Clark ME, Scott IU, Walter LE, Quillen DA, Brigell MG. Twelve-month natural history of dark adaptation in patients with AMD. Optom Vis Sci. 2014;91(8):925–31.
   PubMed Web of Science ®Google Scholar
• Jackson GR, Edwards JG. A short-duration dark adaptation protocol for assessment of age-related maculopathy. J Ocul Biol Dis Infor. 2008;1(1):7–11.
   PubMedGoogle Scholar
• Jackson GR, Felix T, Owsley C. The Scotopic Sensitivity Tester-1 and the detection of early age-related macular degeneration. Ophthalmic Physiol Opt. 2006;26(4):431–37.
   PubMed Web of Science ®Google Scholar
• Owsley C, Jackson GR, White M, Feist R, Edwards D. Delays in rod-mediated dark adaptation in early age-related maculopathy. Ophthalmology. 2001;108(7):1196–202.
   PubMed Web of Science ®Google Scholar
• Owsley C, McGwin G Jr., Jackson GR, Kallies K, Clark M. Cone- and rod-mediated dark adaptation impairment in age-related maculopathy. Ophthalmology. 2007;114(9):1728–35.
   PubMed Web of Science ®Google Scholar
• Owsley C, Clark ME, Huisingh CE, Curcio CA, McGwin G Jr. Visual function in older eyes in normal macular health: association with incident early age-related macular degeneration 3 years later. Invest Ophthalmol Vis Sci. 2016;57(4):1782–89.
   PubMed Web of Science ®Google Scholar
• Barker FM, 2nd, Snodderly DM, Johnson EJ, Schalch W, Koepcke W, Gerss J, et al. Nutritional manipulation of primate retinas, V: effects of lutein, zeaxanthin, and n-3 fatty acids on retinal sensitivity to blue-light-induced damage. Invest Ophthalmol Vis Sci. 2011;52(7):3934–42.
   PubMed Web of Science ®Google Scholar
• Richer S, Cho J, Stiles W, Levin M, Wrobel JS, Sinai M, et al. Retinal spectral domain optical coherence tomography in early atrophic age-related macular degeneration (AMD) and a new metric for objective evaluation of the efficacy of ocular nutrition. Nutrients. 2012;4(12):1812–27.
   PubMed Web of Science ®Google Scholar
• Sadigh S, Cideciyan AV, Sumaroka A, Huang WC, Luo X, Swider M, et al. Abnormal thickening as well as thinning of the photoreceptor layer in intermediate age-related macular degeneration. Invest Ophthalmol Vis Sci. 2013;54(3):1603–12.
   PubMed Web of Science ®Google Scholar
• Owsley C, McGwin G, Jr., Clark ME, Jackson GR, Callahan MA, Kline LB, et al. Delayed rod-mediated dark adaptation is a functional biomarker for incident early age-related macular degeneration. Ophthalmology. 2016;123(2):344–51.
   PubMed Web of Science ®Google Scholar