References
- Nishtala K, Pahuja N, Shetty R, Nuijts RMMA, Ghosh A. Tear biomarkers for keratoconus. Eye Vis. 2016;3(1):19. doi:https://doi.org/10.1186/s40662-016-0051-9.
- Khaled ML, Helwa I, Drewry M, Seremwe M, Estes A, Liu Y. Molecular and histopathological changes associated with keratoconus. Biomed Res Int. 2017;2017:1–16. doi:https://doi.org/10.1155/2017/7803029.
- Karamichos D, Hutcheon AEK, Rich CB, Trinkaus-Randall V, Asara JM, Zieske JD. In vitro model suggests oxidative stress involved in keratoconus disease. Sci Rep. 2014;4:4608. doi:https://doi.org/10.1038/srep04608.
- Thanos S, Oellers P, Meyer Zu Hörste M, Prokosch V, Schlatt S, Seitz B, Gatzioufas Z. Role of thyroxine in the development of keratoconus. Cornea. 2016;35(10):1338–46. doi:https://doi.org/10.1097/ICO.0000000000000988.
- Gordon-Shaag A, Millodot M, Shneor E, Liu Y. The genetic and environmental factors for keratoconus. Biomed Res Int. 2015;2015:795738. doi:https://doi.org/10.1155/2015/795738.
- El Zarif M, Jawad KA, Alió Del Barrio JL, Jawad ZA, Palazón-Bru A, De Miguel MP, Saba P, Makdissy N, Alió JL. Corneal stroma cell density evolution in keratoconus corneas following the implantation of adipose mesenchymal stem cells and corneal laminas: an in vivo confocal microscopy study. Investig Ophthalmol Vis Sci. 2020 Apr 1;61(4):22. doi:https://doi.org/10.1167/iovs.61.4.22. PMID:32301973; PMCID: PMC7401496.
- Flaskó Z, Zemova E, Eppig T, Módis L, Langenbucher A, Wagenpfeil S, Seitz B, Szentmáry N. Hypothyroidism is not associated with keratoconus disease: analysis of 626 subjects. J Ophthalmol. 2019;2019:Article ID:3268595, 8 p. doi:https://doi.org/10.1155/2019/3268595.
- Gatzioufas Z, Thanos S. Acute keratoconus induced by hypothyroxinemia during pregnancy. J Endocrinol Invest. 2008;31(3):262–66. doi:https://doi.org/10.1007/BF03345600.
- Alonso-Merino E, Martin Orozco R, Ruiz-Llorente L, Martinez-Iglesias OA, Velasco-Martin JP, Montero-Pedrazuela A, Fanjul-Rodriguez L, Contreras-Jurado C, Regadera J, Aranda A. Thyroid hormones inhibit TGF-beta signaling and attenuate fibrotic responses. Proc Natl Acad Sci USA. 2016 Jun;113(24):E3451–60. doi:https://doi.org/10.1073/pnas.1506113113.
- Diniz GP, Carneiro-Ramos MS, Barreto-Chaves MLM. Thyroid hormone increases TGF-β 1 in cardiomyocytes cultures independently of Angiotensin II type 1 and type 2 receptors. Int J Endocrinol. 2010;2010:Article ID:384890, 7 p. doi:https://doi.org/10.1155/2010/384890.
- Schmidt MR, Maeng M, Kristiansen SB, Andersen HR, Falk E. The natural history of collagen and α-actin expression after coronary angioplasty. Cardiovasc Pathol. 2004 Sep 1;13(5):260–67. doi:https://doi.org/10.1016/j.carpath.2004.06.001.
- Fini ME. Keratocyte and fibroblast phenotypes in the repairing cornea. Prog Retin Eye Res. 1999 Jul;18(4):529–51. doi:https://doi.org/10.1016/S1350-9462(98)00033-0.
- Foster JW, Gouveia RM, Connon CJ. Low-glucose enhances keratocyte-characteristic phenotype from corneal stromal cells in serum-free conditions. Sci Rep. 2015 Jun 3;5. doi:https://doi.org/10.1038/srep10839.
- El-Massry A, Doheim MF, Iqbal M, Fawzy O, Said OM, Yousif MO, Badawi AE, Tawfik A, Abousamra A. Association between keratoconus and thyroid gland dysfunction: a cross-sectional case-control study. J Refract Surg. 2020 Apr 1;36(4):253–57. doi:https://doi.org/10.3928/1081597X-20200226-03.
- Stachon T, Stachon A, Hartmann U, Seitz B, Langenbucher A, Szentmáry N. Urea, uric acid, prolactin and fT4 concentrations in aqueous humor of keratoconus patients. Curr Eye Res. 2017;42(6):842–46. doi:https://doi.org/10.1080/02713683.2016.1256413.
- Mondal S, Raja K, Schweizer U, Mugesh G. Chemistry and biology in the biosynthesis and action of thyroid hormones. AngewChem Int Ed Engl. 2016 Jun 27;55(27):7606–30. doi:https://doi.org/10.1002/anie.201601116. Epub 2016 May 25. PMID: 27226395.
- Priyadarsini S, McKay TB, Sarker-Nag A, Karamichos D. Keratoconus in vitro and the key players of the TGF-β pathway. Mol Vis. 2015;21:577–88.
- Bai S, Cao X. A nuclear antagonistic mechanism of inhibitory Smads in transforming growth factor-β signaling. J Biol Chem. 2002 Feb 8;277(6):4176–82. doi:https://doi.org/10.1074/jbc.M105105200.
- Berardi AC, Oliva F, Berardocco M, la Rovere M, Accorsi P, Maffulli N. Thyroid hormones increase collagen I and cartilage oligomeric matrix protein (COMP) expression in vitro human tenocytes. Muscles Ligaments Tendons J. 2014;4(3):285–91. doi:https://doi.org/10.32098/mltj.03.2014.04.
- Birk DE, Brückner P. Collagens, suprastructures, and collagen fibril assembly. In: Mecham R, editor. The extracellular matrix. Berlin: Springer Verlag; 2010. p. 77–116. doi:https://doi.org/10.1007/978-3-642-16555-9_3.
- Foster JW, Shinde V, Soiberman US, Sathe G, Liu S, Wan J, Qian J, Dauoud Y, Pandey A, Jun AS, et al. Integrated stress response and decreased ECM in cultured stromal cells from keratoconus corneas. Invest Ophthalmol Vis Sci. 2018 Jun;59(7):2977–86. doi:https://doi.org/10.1167/iovs.18-24367.