Histopathological effects of topical ophthalmic preservatives on rat corneoconjunctival surface

References

• Gassett, A. R., Ishii, Y., Kaufman, H. E. and Miller, T. (1974) Cytotoxicity of ophthalmic preservatives. Am. J. Ophthalmol. 78, 98–105.
   PubMed Web of Science ®Google Scholar
• Burstein, N. L. (1980) Corneal cytotoxicity of topically applied drugs, vehicles and preservatives. Surv. Ophthalmol. 25, 15–30.
   PubMed Web of Science ®Google Scholar
• Burstein, N. L. (1985) The effects of topical drugs and preservatives on the tears and corneal epithelium in dry eye. Trans. Ophthalmol. Soc. UK, 104, 402–409.
   PubMedGoogle Scholar
• Olson, R. J. and White, G. L. (1990) Preservatives in ophthalmic topical medications. Cornea, 9, 363–364.
   PubMed Web of Science ®Google Scholar
• Burstein, N. L. and Klyce, S. D. (1977) Electrophysiologic and morphologic effects of ophthalmic preparations on rabbit cornea epithelium. Invest. Ophthalmol Vis. Sci., 16, 899–911.
   PubMed Web of Science ®Google Scholar
• Burstein, N. L. (1980) Preservative cytotoxic threshold for benzalkonium chloride and chlorhexidine digluconate in cat and rabbit corneas. Invest. Ophthalmol. Vis. Sci. 19, 308–313.
   PubMed Web of Science ®Google Scholar
• Baines, M. G., Cai, F. and Backman, H. A. (1991) Ocular hypersensitivity to Thimerosal in rabbits. Invest. Ophthalmol. Vis. Sci. 32, 2259–2265.
   PubMed Web of Science ®Google Scholar
• Wilson, F. M. (1984) Adverse external ocular effects of topical ophthalmic therapy: an epidemiologic, laboratory, and clinical study. Trans. Am. Ophthalmol. Soc. 81, 854–965.
   Google Scholar
• Baudouin, C. (1996) Side effects of antiglaucomatous drugs on the ocular surface. Curr. Opin. Ophthalmol. 7, 80–86.
   PubMedGoogle Scholar
• Broadway, D. C., Grierson, I., O'Brien, C. and Hitchings, R. A. (1994) Adverse effects of topical antiglaucoma medication: I. the conjunctival cell profile. Arch. Ophthalmol. 112, 1437–1445.
   PubMed Web of Science ®Google Scholar
• Broadway, D. C., Grierson, I., O'Brien, C. and Hitchings, R. A. (1994) Adverse effects of topical antiglaucoma medication: II. the outcome of filtration surgery. Arch. Ophthalmol. 112, 1446–1454.
   PubMed Web of Science ®Google Scholar
• Pfister, R. R. and Burstein, N. (1976) The effects of ophthalmic drugs, vehicles, and preservatives on corneal epithelium: a scanning electron microscope study. Invest. Ophthalmol. Vis. Sci. 15, 246–259.
   Web of Science ®Google Scholar
• Ichijima, H., Petroll, W. M., Jester, J. V. and Cavanagh, H. D. (1992) Confocal microscopic studies of living rabbit cornea treated with benzalkonium chloride. Cornea, 11, 221–225.
   PubMed Web of Science ®Google Scholar
• Imperia, P. S., Lazarus, H. M., Botti, R. E., Jr. and Lass, J. H. (1986) An in vitro method for measuring ophthalmic preservative cytotoxicity. J. Toxicol. Cut. Ocular Toxicol, 5, 309–317.
   Web of Science ®Google Scholar
• Tripathi, B. J., Tripathi, R. C. and Kolli, S. P. (1992) Cytotoxicity of ophthalmic preservatives on human corneal epithelium. Lens Eye Toxic Res. 9, 361–375.
   PubMedGoogle Scholar
• Lopez Bernal, D. and Ubels, J. L. (1991) Quantitative evaluation of the corneal epithelial barrier: effect of artificial tears and preservatives. Curr. Eye Res. 10, 645–656.
   PubMed Web of Science ®Google Scholar
• Brandt, J. D., Wittpenn, J. R., Jay Katz, L., Steinmann, W. N. and Spaeth, G. L. (1991) Conjunctival impression cytology in patients with glaucoma using long-term topical medication. Am. J. Ophthalmol. 112, 297–301.
   PubMed Web of Science ®Google Scholar
• Sherwood, M. B., Grierson, I., Millar, L. and Hitchings, R. A. (1989) Long-term morphologic effects of antiglaucoma drugs on the conjunctiva and Tenon's capsule in glaucomatous patients. Ophthalmology, 96, 327–335.
   PubMed Web of Science ®Google Scholar
• Baudouin, C., Garcher, C., Haouat, N., Bron, A. and Gastaud, P. (1994) Expression of inflammatory membrane markers by conjunctival cells in chronically treated glaucoma patients. Ophthalmology, 101, 454–460.
   PubMed Web of Science ®Google Scholar
• Smith, D. L., Rabbani, R., Skuta, G. L., Cruess, D. F., Kincaid, M. C. and Kao, S. F. (1991) The effects of glaucoma medications on Tenon's capsule and conjunctiva in the rabbit. Ophthalmol. Surg. 22, 336–340.
   PubMedGoogle Scholar
• Seto, S. K., Gillette, T. E. and Chandler, J. W. (1987) HLA DR+/T6- Langerhans cells of the human cornea. Invest. Ophthalmol. Vis. Sci. 28, 1719–1726.
   PubMed Web of Science ®Google Scholar
• Philipp, W. and Göttinger, W. (1991) T6 positive Langerhans cells in diseased corneas. Invest. Ophthalmol. Vis. Sci. 32, 2494–2497.
   Web of Science ®Google Scholar
• Choudhury, A., Pakalnis, V. A. and Bowers, W. E. (1995) Function and cell surface phenotype of dendritic cells from rat cornea. Invest. Ophthalmol. Vis. Sci. 36, 2602–2613.
   PubMed Web of Science ®Google Scholar
• Rigal, D., Menerath, J. M. and Rouleau, J. (1993) Epithelium et médicaments. In L'épithélium Cornéen ( Ed. Rigal, D.). pp. 391–419. Masson, Paris.
   Google Scholar
• Ansel, H. C. and Popovich, N. G. (1990) Dosage form design: ingredients, product formulation, manufacturing practice. In Pharmaceutical Dosage Forms and Drug Delivery Systems ( Eds. Ansel, H. C. and Popovich, N. G.). P. 108. Lea & Febiger, Philadelphia.
   Google Scholar
• Neville, R., Dennis, P., Sens, D. and Crouch, R. (1986) Preservative cytotoxicity to cultured corneal epithelial cells. Curr. Eye Res. 5, 367–372.
   PubMed Web of Science ®Google Scholar
• Greiner, J. V., Peace, D. G., Baird, R. and Allansmith, M. R. (1985) Effects of eye rubbing on the conjunctiva as a model of ocular inflammation. Am. J. Ophthalmol. 100, 45–50.
   PubMed Web of Science ®Google Scholar
• Feldman, R. M., Gross, R. L., Spaeth, G. L., Steinmann, W. C., Varma, R., Katz, L. J., Wilson, R. P., Moster, M. R. and Spiegel, D. (1989) Risk factors for the development of Tenon's capsule cysts after trabeculectomy. Ophthalmology, 96, 336–341.
   PubMed Web of Science ®Google Scholar
• Young, T. L., Higginbotham, E. J., Zou, X. and Farber, M. D. (1990) Effects of topical glaucoma drugs on fistulized rabbit conjunctiva. Ophthalmology, 97, 1423–1427.
   PubMed Web of Science ®Google Scholar
• Herreras, J. M., Pastor, J. C., Calonge, M. and Asensio, V. M. (1992) Ocular surface alteration after long term treatment with an antiglaucomatous drug. Ophthalmology, 99, 1082–1088.
   PubMed Web of Science ®Google Scholar
• Marquardt, R. and Schubert, T. (1991) Modification of tear film break-up time by beta-blocker eye drops without preservatives. Klin Monatsbl Augenheilkd, 199, 75–78.
   PubMed Web of Science ®Google Scholar
• Kuppens, E. V., de Jong, C. A., Stiwijk, T. R., de Keizer, R. J. and van Best, J. A. (1995) Effect of timolol with and without preservative on the basal tear turnover in glaucoma. Br. J. Ophthalmol. 79, 339–342.
   PubMed Web of Science ®Google Scholar
• Williams, D. E., Nguyen, K. D., Shapourifar-Tehrani, S., Steinmann, W. N. and Spaeth, G. L. (1992) Effects of timolol, betaxolol and levobunolol on human Tenon's fibroblasts in tissue culture. Invest. Ophthalmol. Vis. Sci. 33, 2233–2241.
   PubMed Web of Science ®Google Scholar