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Annals of Tropical Paediatrics
International Child Health
Volume 14, 1994 - Issue 3
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Original Articles

High dose methylprednisolone therapy in children with onyalai

P. B. HesselingDepartment of Paediatrics and Child Health, University of Stellenbosch, Tygerberg
,
S. SmithDepartment of Paediatrics and Child Health, University of Stellenbosch, Tygerberg
,
O. OosthuizenDepartment of Medicine, Windhoek State Hospital Windhoek, Namibia, South Africa
&
S. AmadhilaMinistry of Health and Social Services, Windhoek, Namibia, South Africa
Pages 239-243 | Received 23 Feb 1994, Published online: 13 Jul 2016

References

  • Wellman FC. Brief conspectus of the tropical diseases common in the Highlands of West Central Africa. J Trop Med Hyg 1904; 7: 52–6.
  • Hesseling PB. Onyalai. Clin Haematol 1992; 2: 457–73.
  • Metz J, Kramer S, Cassel R. Acute idiopathic thrombocytopenia in the Bantu. S Afr J Med Sci 1958; 23: 93–100.
  • Hesseling PB. Onyalai at Rundu, Namibia 1981–1988: age, sex, morbidity, mortality and seasonal variation of 612 hospitalized patients. Trans R Soc Trop Med Hyg 1990; 84: 605–7.
  • Hesseling PB. Onyalai: an epidemiological study. MD Thesis, University of Stellenbosch, 1983.
  • Hesseling PB, Girdle-Brown B, Smit J. Onyalai: treatment with prednisolone, intravenous gammaglobulin and ascorbic acid. S Afr Med J 1984; 66: 917–18.
  • Hesseling PB, Girdle-Brown B, Smit J. Onyalai: therapeutic effects of vincristine sulphate. A prospective randomised trial in 40 patients in Kavango, Namibia. S Afr Med J 1986; 70: 201–2.
  • Hesseling PB. High dose immunoglobulin therapy in four patients with onyalai. Trans R Soc Trop Med Hyg 1991; 85: 131–2.
  • Hara T, Miyazaki S, Yoshida N, Goya N. High doses of gamma globulin and methylprednisolone therapy for idiopathic thrombocytopenic purpura in children. Bur J Pediatr 1985; 144: 240–2.
  • Von Dem Borne AEG Kr, Vos JJE, Pegels JG, Thomas LLM, Van der Lelie H. High dose intravenous methylprednisolone or high dose intravenous gammaglobulin for autoimmune thrombocytopenia. Br Med J 1988; 296: 249–50.
  • Del Principe D, Menichelli A, Mori PG, et al. Phase II trial of methylprednisolone pulse therapy in childhood chronic thrombocytopenia. Acta Haematol 1987; 77: 226–30.
  • Özsoylu S, Irken G, Karabent A. High-dose intravenous methylprednisolone for acute childhood idiopathic thrombocytopenic purpura. Eur J Haematol 1989; 42: 431–5.
  • Özsoylu S. High dose intravenous methylprednisolone for the treatment of childhood chronic idiopathic thrombocytopenic purpura in children. Acta Haematol 1988; 1: 55–6.
  • Hesseling PB, Oosthuizen E, Pretorius L, Swart A, Steynberg J. Splenectomy in onyalai. A report on 5 cases. S Afr Med J 1984; 66: 580–2.

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