Deformation and Mechanical Characteristics of Compacted Binary Mixtures of Plastic (Microcrystalline Cellulose), Elastic (Sodium Starch Glycolate), and Brittle (Lactose Monohydrate) Pharmaceutical Excipients

References

• Ahmat , N. , H. Ugail , and G. González Castro . 2012 . Elastic and plastic contact law for simulation of tablet crushing using the biharmonic equation . International Journal of Pharmaceutics 427 ( 2 ): 170 – 176 .
   PubMed Web of Science ®Google Scholar
• Akseli , I. , N. Ladyzhynsky , J. Katz , and X. He . 2012 . Development of predictive tools to assess capping tendency of tablet formulations . Powder Technology 236 : 139 – 148 .
   Web of Science ®Google Scholar
• Alderborn , G. 2007 . Tablets and compaction . Design and Manufacture of Medicine 441 – 482 .
   Google Scholar
• Alderborn , G. , and C. Nystrom . 1996 . Pharmaceutical Powder Compaction Technology . Jersey , UK : Informa Healthcare .
   Google Scholar
• Armstrong , N. A. , and F. S. S. Morton . 1977. The effect of granulating agents on the elasticity and plasticity of powders. Powder Bulk Solids Technol. 1:32.
   Google Scholar
• Edge , S. , D. F. Steele , D. F. , J. N. Staniforth , A. Chen , and P. M. Woodcock . 2002 . Powder compaction properties of sodium starch glycolate disintegrants . Drug Development and Industrial Pharmacy 28 : 989 – 999 .
   PubMed Web of Science ®Google Scholar
• Garr , J. S. M. , and M. H. Rubinstein . 1991 . The effect of rate of force application on the properties of microcrystalline cellulose and dibasic calcium phosphate mixtures . International Journal of Pharmaceutics 73 : 75 – 80 .
   Web of Science ®Google Scholar
• Karehill , P. G. , M. Glazer , and C. Nyström . 1990 . Studies on direct compression of tablets. XXIII. The importance of surface roughness for the compactability of some directly compressible materials with different bonding and volume reduction properties . International Journal of Pharmaceutics 64 : 35 – 43 .
   Web of Science ®Google Scholar
• Mahmoodi , F. , G. Alderborn , and G. Frenning . 2012 . An experimental evaluation of an effective medium based compaction equation . European Journal of Pharmaceutical Sciences 46 : 49 – 55 .
   PubMed Web of Science ®Google Scholar
• Mohammed , H. , B. J. Briscoe , and K. G. Pitt . 2005 . The interrelationship between the compaction behaviour and the mechanical strength of pure pharmaceutical tablets . Chemical Engineering Science 60 : 3941 – 3947 .
   Web of Science ®Google Scholar
• Mohammed , H. , B. J. Briscoe , K. G. Pitt . 2006 . A study on the coherence of compacted binary composites of microcrystalline cellulose and paracetamol . European Journal of Pharmaceutics and Biopharmaceutics 63 : 19 – 25 .
   PubMed Web of Science ®Google Scholar
• Newton , J. M. , G. Rowley , J. T. Fell , D. G. Peacock , K. Ridgway . 1971 . Computer analysis of the relation between tablet strength and compaction pressure . Journal of Pharmacy and Pharmacology 23 : 195 – 201 .
   PubMed Web of Science ®Google Scholar
• Nystrom , C. , G. Alderborn , M. Duberg , and P.-G. Karehill . 1993 . Bonding surface area and bonding mechanism-two important factors for the understanding of powder comparability . Drug Development and Industrial Pharmacy 19 : 2143 – 2196 .
   Web of Science ®Google Scholar
• Pabari , R. M. , and Z. Ramtoola . 2012 . Application of face centred central composite design to optimise compression force and tablet diameter for the formulation of mechanically strong and fast disintegrating orodispersible tablets . International Journal of Pharmaceutics 430 ( 1–2 ): 18 – 25 .
   PubMed Web of Science ®Google Scholar
• Patel , S. , A. Mohan Kaushal , and A. K. Bansal . 2011 . The effect of starch paste and sodium starch glycolate on the compaction behavior of wet granulated acetaminophen formulations . Journal of Excipients and Food Chemicals 2 ( 3 ): 64 – 72 .
   Google Scholar
• Pitt , K. , and C. Sinka . 2007 . Tableting . In Handbook of powder technology , eds. by A. D. Salman , M. J. Hounslow , and J. P. K. Seville , vol. 11 , 735 – 778 . Amsterdam : Elsevier Science B.V.
   Google Scholar
• Řehula , M. , R. Adámek , and V. Špaček . 2012 . Stress relaxation study of fillers for directly compressed tablets . Powder Technology 217 : 510 – 515 .
   PubMed Web of Science ®Google Scholar
• Rudnick , A. , A. R. Hunter , and F. C. Holden . 1963 . An analysis of the diametral-compression test . Materials Research and Standards 1 : 283 – 288 .
   Google Scholar
• Šantl , M. , I. Ilić , F. Vrečer , and S. Baumgartner . 2011 . A compressibility and compactibility study of real tableting mixtures: the impact of wet and dry granulation versus a direct tableting mixture . International Journal of Pharmaceutics 414 : 131 – 139 .
   PubMed Web of Science ®Google Scholar
• Shamsudin , I. S. , M. S. Anuar , and S. M. Tahir . 2012 . Compaction of sweet potato (Ipomoea batatas L.) and stevia rebaudiana food powders . Particulate Science and Technology 30 : 136 – 144 .
   Web of Science ®Google Scholar
• Sinka , I. C. , K. G. Pitt , and A. C. Francis Cocks . 2007 . The strength of pharmaceutical tablets . In Handbook of Powder Technology , eds. by A. D. Salman , M. Ghadiri , and M. J. Hounslow , vol. 12 , 941 – 970 . Amsterdam : Elsevier Science B.V.
   Google Scholar
• Uddhav , B. S. 2006 . Despite increasing interest in controlled-release drug delivery systems, the most common tablets are those intended to be swallowed whole and to disintegrate and release their medicaments rapidly in the gastrointestinal tract (GIT). http://www.pharmainfo.net/reviews/current-status-tablet-disintegrantsa-review (accessed August 14, 2012).
   Google Scholar