Study of physicochemical properties of flutamide-loaded Ocimum basilicum microspheres with ex vivo mucoadhesion and in vitro drug release

References

• Aizawa, Y., I. Ikemoto, K. Kishimoto, T. Wada, H. Yamazaki, Y. Ohishi, H. Kiyota, N. Furata, H. Suzuki, and M. Ueda. 2003. Flutamide induced hepatic dysfunction in relation to steady-state plasma concentrations of flutamide and its metabolites. Molecular and Cellular Biochemistry, 252:149–56.
   PubMed Web of Science ®Google Scholar
• Anitha, A., S. Uthaman, S. Nair, R. Jayakumar, and V. Lakshmanan. 2012. Delivery system of flutamide loaded chitosan-dextran sulphate nanoparticles for prostate cancer. Journal of Biomedical Nanotechnology 9:1–13.
   Web of Science ®Google Scholar
• Baria, A. H., R. P. Patel, A. M. Suthar, and R. B. Parmar. 2009. Formulation development and evaluation of sustained release aceclofenac suppository. International Journal of Pharmaceutical Science and Drug Research 1 (2):71–73.
   Google Scholar
• Campos, E. 2013. Designing polymeric microparticle for biomedical and industrial application. European Polymer Journal 49:2005–21. doi:10.1016/j.eurpolymj.2013.04.033
   Web of Science ®Google Scholar
• Celebi, N., M. Iscanoglu, and T. Degim. 1991. The release of naproxen in fatty suppository bases by beta-cyclodextrin complexation. Pharmazie 46 (12):863–75.
   PubMed Web of Science ®Google Scholar
• De Boer, A. G., and D. D. Breimer. 1997. Hepatic first-pass effect and controlled drug delivery following rectal administration. Advanced Drug Delivery Reviews 28 (2):229–37.
   Web of Science ®Google Scholar
• De Boer, A. G., F. Moolenaar, L. G. J. de Leede, and D. D. Breimer. 1982. Rectal drug administration: Clinical pharmacokinetic considerations. Clinical Pharmacokinetics 7 (4):285–311.
   PubMed Web of Science ®Google Scholar
• Donnell, P. B. O., and J. W. Mcginity. 1997. Preparation of microspheres by the solvent evaporation technique. Advanced Drug Delivery Reviews 28:25–42. doi:10.1016/s0169-409x(97)00049-5
   PubMed Web of Science ®Google Scholar
• Elgindy, N., K. Elkhodairy, A. Molokhia, and A. Elzoghby. 2010. Lyophilization monophase solution technique for improvement of the physiochemical properties of an anticancer drug, Flutamide. European Journal of Pharmaceutics and Biopharmaceutics 74:397–405. doi:10.1016/j.ejpb.2009.11.011
   PubMed Web of Science ®Google Scholar
• Elzoghby, A., M. W. Helmy, W. M. Samy, and N. A. Elgindy. 2013. Spray-dried casein-based micelles as a vehicle for solubilization and controlled delivery of flutamide: Formulation, characterization, and in vivo pharmacokinetics. European Journal of Pharmaceutics and Biopharmaceutics 84 (3):487–96. doi:10.1016/j.ejpb.2013.01.005
   PubMed Web of Science ®Google Scholar
• Esposito, E., R. Roncarati, R. Cortesi, F. Cervellati, and C. Nastruzzi. 2000. Production of Eudragit microparticles by spray drying technique: Influence of experimental parameters on morphological and dimensional characteristics. Pharmaceutical Development and Technology 5:267–78. doi:10.1081/pdt-100100541
   PubMed Web of Science ®Google Scholar
• Fizazi, K., and Navone, N. M. 2005. Preclinical models of prostate cancer. Bulletin du Cancer 92:129–41.
   PubMed Web of Science ®Google Scholar
• Garekani, H. A., Z. Fatemi Moghaddam, and F. Sadeghi. 2013. Organic solution versus aqueous dispersion of Eudragit RS in Preparation of sustained release microparticles of theophylline using spray drying. Colloids and Surfaces B: Biointerfaces 108:374–79. doi:10.1016/j.colsurfb.2013.03.012
   PubMed Web of Science ®Google Scholar
• Ghaderi, R., P. Artursson, and J. Carlfors. 2000. A new method for preparing biodegradable particles and entrapment of hydrocortisone in DL-PLG microparticles using supercritical fluids. European Journal of Pharmaceutical Sciences 6 (10):1–9. doi:10.1016/s0928-0987(99)00079-2
   Web of Science ®Google Scholar
• Gronberg, H. 2003. Prostate cancer epidemiology. Lancet 361:859–64.
   PubMed Web of Science ®Google Scholar
• Hodgson, M. C., I. Astapova, A. N. Hollenberg, and S. P. Balk. 2007. Activity of androgen receptor antagonist bicalutamide in prostate cancer cells is independent of NCoR and SMRT corepressors. Cancer Research 678:8388–95. doi:10.1158/0008-5472.can-07-0617
   Web of Science ®Google Scholar
• Ige, P. P., K. Agrawal, and U. Patil. 2015. Enhanced in vitro dissolution of iloperidone using caesalpinia pulcherrima mucoadhesive microspheres. Beni Suef University Journal of Basic and Applied Sciences 4:26–32. doi:10.1016/j.bjbas.2015.02.004
   Google Scholar
• Ige, P. P., R. K. Baria, and S. G. Gattani. 2013. Fabrication of fenofibrate nanocrystals by probe sonication for enhancement of dissolution rate and oral bioavailability. Colloids and Surfaces B: Biointerfaces 108:366–73. doi:10.1016/j.colsurfb.2013.02.043
   PubMed Web of Science ®Google Scholar
• Ige, P. P., and S. G. Gattani. 2012. Design and in vitro and in vivo characterization of mucoadhesive matrix pellet of metformin hydrochloride for oral controlled release: A technical note. Archives of Pharmacal Research 35 (3):487–98. doi:10.1007/s12272-012-0312-7
   PubMed Web of Science ®Google Scholar
• Kristmundsdottir, T., Ó. S. Gudmundsson, and K. Ingvarsdóttir. 1996. Release of diltiazem from eudragit microparticles prepared by spray drying. International Journal of Pharmaceutics 137:159–65. doi:10.1016/0378-5173(96)04509-7
   Web of Science ®Google Scholar
• Leede, L. G. J., A. G. de Boer, E. Pörtzgen, J. Feijen, and D. D. Breimer. 1986. Rate-controlled rectal drug delivery in man with a hydrogel preparation. Journal of Controlled Release 4 (1):17–24. doi:10.1016/0168-3659(86)90029-5
   Google Scholar
• Martins, R. M., S. V. Pereira, S. Siqueira, W. F. Salomão, and L. A. P. Freitas. 2013. Curcuminoid content and antioxidant activity in spray dried microparticles containing turmeric extract. Food Research International 50:657–63. doi:10.1016/j.foodres.2011.06.030
   Web of Science ®Google Scholar
• Milone, M. R., B. Pucci, F. Bruzzese, C. Carbone, G. Piro, S. Costantini, F. Capone, A. Leone, E. Di Gennaro, M. Caraglia, and A. Budillon. 2013. Acquired resistance to zolendronic acid and the parallel acquisition of an aggressive phenotype are mediated by P-38-MAP Kinase activation in prostate cancer cells. Cell Death and Disease 4:1–11.
   Web of Science ®Google Scholar
• Motlekar, N., and B. B. Youan. 2008. Optimization and experimental parameters for the production of LMWH-loaded polymeric microspheres. Journal of Drug Design Development and Therapy 2:39–47.
   Google Scholar
• Osano, J. P., S. H. Hosseini-Parvar, L. Matia-Merino, and M. Golding. 2014. Emulsifying properties of novel polysaccharides extracted from basil seed (Ocimum bacilicum Linn) Effect of polysaccharides and protein content. Food Hydrocolloids 37:40–48. doi:10.1016/j.foodhyd.2013.09.008
   Web of Science ®Google Scholar
• Palmieri, G., and G. Bonacucina. 2001. Spray drying as a method for microparticulate controlled release systems preparation: Advantages and limits I. water-soluble drugs. Drug Development and Industrial Pharmacy 27 (3):195–204. doi:10.1081/ddc-100000237
   PubMed Web of Science ®Google Scholar
• Paradkar, A., A. P. Pawar, J. K. Chordiya, V. B. Patil, and A. R. Ketkar. 2002. Spherical crystallization of celecoxib. Drug Development and Industrial Pharmacy 28 (10):1213–20. doi:10.1081/ddc-120015354
   PubMed Web of Science ®Google Scholar
• Pardeshi, C. V., P. V. Rajput, V. S. Belgamwar, and A. R. Tekade. 2012. Formulation, optimization and evaluation of spray dried mucoadhesive microspheres as intranasal carriers for valsartan. Drug Delivery 29:103–14. doi:10.3109/02652048.2011.630106
   Web of Science ®Google Scholar
• Patel, D. M. 2007. Seed mucilage from Ocimum Americanum Linn as disintegrant in tablets: Separation and evaluation. Indian Journal of Pharmaceutical Science 4:431–35.
   Google Scholar
• Patil, S., A. Babbar, R. Mathur, A. Mishra, and K. Sawant. 2010. Mucoadhesive chitosan microspheres of carvedilol for nasal administration. Journal of Drug Targeting 18 (40):321–31. doi:10.3109/10611861003663523
   PubMed Web of Science ®Google Scholar
• Peppas, N. A., R. Gurny, E. Doelker, and P. Buri. 1980. Modeling of drug diffusion through swellable polymeric systems. Journal of Membrane Science 7 (3):241–53. doi:10.1016/s0376-7388(00)80471-8
   Web of Science ®Google Scholar
• Piccionello, P., G. Pitarresi, A. Pace, D. Triolo, P. Picone, S. Buscemi, and G. Giammona. 2012. Fluorinated and pegylated polyaspartamide derivative to increase solubility and efficacy of flutamide. Journal of Drug Targeting 20:433–41. doi:10.3109/1061186x.2012.680961
   PubMed Web of Science ®Google Scholar
• Posti, J., K. Katila, and T. Kostiainen. 2000. Dissolution rate limited bioavailability of Flutamide, and in vitro- in vivo correlation. European Journal of Pharmaceutics and Biopharmaceutics 49:35–39. doi:10.1016/s0939-6411(99)00061-2
   PubMed Web of Science ®Google Scholar
• Prajapati, S. K., P. Tripathi, U. Ubaidulla, and V. Anand. 2008. Design and development of gliclazide mucoadhesive microcapsules: In vitro and in vivo evaluation. AAPS PharmSciTech 9:224–30. doi:10.1208/s12249-008-9041-0
   PubMed Web of Science ®Google Scholar
• Prajapati, V., G. Jani, N. G. Moradiya, and N. P. Randeria. 2013. Pharmaceutical applications of various natural gums, mucilages and their modified forms. Carbohydrate Polymer 92:1685–99. doi:10.1016/j.carbpol.2012.11.021
   PubMed Web of Science ®Google Scholar
• Prasanna, L. J., B. Deepthi, and N. R. Rao. 2012. Rectal drug delivery: A promising route for enhancing drug absorption. Asian Journal Research and Pharmaceutical Science 2:143–49.
   Google Scholar
• Rafe, A., S. M. A. Razavi, and R. Farhoosh. 2013. Rheology and microstuctured of basil seed gum and β-lactoglobulin mixed gel. Food Hydrocolloids 30:134–42. doi:10.1016/j.foodhyd.2012.05.016
   Web of Science ®Google Scholar
• Ritger, P. L., and N. A. Peppas. 1987. A simple equation for description of solute release II Fickian and anomalous release from swellable devices. Journal of Controlled Release 5:37–42. doi:10.1016/0168-3659(87)90035-6
   Google Scholar
• Sahoo, N. G., A. Abbas, and C. M. Li. 2008. Micro/nanoparticle design and fabrication for pharmaceutical drug preparation and delivery applications. Current Drug Therapy 3:78–97. doi:10.2174/157488508784221253
   Google Scholar
• Samy, E. M. 2000. Improvement availability of allopurinol from pharmaceutical dosage forms I-suppositories. European Journal of Pharmaceutics and Biopharmaceutics 49:119–27. doi:10.1016/s0939–6411(99)00079-x
   PubMed Web of Science ®Google Scholar
• Samy, W. S. 2012. Class II drug: A dissolution/bioavailability challenge: Flutamide-loaded spray dried lactose for dissolution control. International Journal of Drug Development and Research 4 (2):195–204.
   Google Scholar
• Tonon, R. V., and C. Brabet. 2008. Influence of process condition on the physic-chemical properties of acacia powder produced by spray drying. Journal of Food Engineering 3:411–18.
   Web of Science ®Google Scholar
• Vincent, J., G. Lemagnen, P. Gueroult, D. Larrouture, and C. Tuleu. 2014. Rectal route in the 21st century to treat children. Advanced Drug Delivery Reviews 73:34–49. doi:10.1016/j.addr.2014.05.012
   PubMed Web of Science ®Google Scholar
• Wong, S. M., I. W. Kellaway, and S. Murdan. 2006. Enhancement of the dissolution rate and oral absorption of a poorly water soluble drug by formation of surfactant-containing microparticles. International Journal of Pharmaceutics 317:61–68. doi:10.1016/j.ijpharm.2006.03.001
   PubMed Web of Science ®Google Scholar
• Xu, L. M., Q.-X. Zhang, Y. Zhou, H. Zhao, J.-X. Wang, and J.-F. Chen. 2012. Engineering drug ultrafines particles of beclomethasone dipropionate for dry powder inhalation. International Journal of Pharmaceutics 436:1–9. doi:10.1016/j.ijpharm.2012.06.038
   PubMed Web of Science ®Google Scholar
• Yahagi, R., H. Onishi, and Y. Machida. 1999. Preparation evaluation of double-phased mucoadhesive suppositories of lidocaine utilizing carbapol and white beeswax. Journal of Controlled Release 61:1–8. doi:10.1016/s0168-3659(99)00111-x
   PubMed Web of Science ®Google Scholar
• Zuo, Z., Y. K. Tam, J. Diakur, and L. I. Wiebe. 2002. Hydroxy propyl-B-cyclodextrin-flutamide inclusion complex II. Oral and intravenous pharmacokinetics of Flutamide in the rat. Journal of Pharmacy and Pharmaceutical Science 5 (3):292–98.
   PubMed Web of Science ®Google Scholar