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Research Articles

Fabrication of swellable PEGylated hydrogel by free radical polymerization for controlled delivery of non-steroidal anti-inflammatory drug; characterization and statistical analysis

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References

  • Ahmed, E. M. 2015. Hydrogel: Preparation, characterization, and applications: A review. Journal of Advanced Research 6 (2):105–21. doi:10.1016/j.jare.2013.07.006.
  • Akhtar, M. F., M. Hanif, and N. M. Ranjha. 2016. Methods of synthesis of hydrogels … A review. Saudi Pharmaceutical Journal 24 (5):554–9. doi:10.1016/j.jsps.2015.03.022.
  • Asghar, S., N. Akhtar, M. U. Minhas, and K. U. Khan. 2021. Bi-polymeric spongy matrices through cross-linking polymerization: Synthesized and evaluated for solubility enhancement of acyclovir. AAPS PharmSciTech 22 (5):1–16. doi:10.1208/s12249-021-02054-2.
  • Bhattacharyya, R., and S. K. Ray. 2015. Removal of Congo red and methyl violet from water using nano clay filled composite hydrogels of poly acrylic acid and polyethylene glycol. Chemical Engineering Journal 260:269–83. doi:10.1016/j.cej.2014.08.030.
  • Bhattarai, N., J. Gunn, and M. Zhang. 2010. Chitosan-based hydrogels for controlled, localized drug delivery. Advanced Drug Delivery Reviews 62 (1):83–99. doi:10.1016/j.addr.2009.07.019.
  • Buenger, D., F. Topuz, and J. Groll. 2012. Hydrogels in sensing applications. Progress in Polymer Science 37 (12):1678–719. doi:10.1016/j.progpolymsci.2012.09.001.
  • Bukhari, S. M. H., S. Khan, M. Rehanullah, and N. M. Ranjha. 2015. Synthesis and characterization of chemically cross-linked acrylic acid/gelatin hydrogels: Effect of pH and composition on swelling and drug release. International Journal of Polymer Science 2015:1–15. doi:10.1155/2015/187961.
  • Chen, S., M. Liu, S. Jin, and B. Wang. 2008. Preparation of ionic-crosslinked chitosan-based gel beads and effect of reaction conditions on drug release behaviors. International Journal of Pharmaceutics 349 (1–2):180–7. doi:10.1016/j.ijpharm.2007.08.029.
  • Chen, M., Y. Zhang, V. Dusevich, Y. Liu, Q. Yu, and Y. Wang. 2014. Non-thermal atmospheric plasma brush induces HEMA grafting onto dentin collagen. Dental Materials 30 (12):1369–77. doi:10.1016/j.dental.2014.10.004.
  • Dafader, N., M. Adnan, M. Haque, D. Huq, and F. Akhtar. 2011. Study on the properties of copolymer hydrogel obtained from acrylamide/2-hydroxyethyl methacrylate by the application of gamma radiation. African Journal of Pure and Applied Chemistry 5 (5):111–8.
  • Datta, A. 2007. Characterization of polyethylene glycol hydrogels for biomedical applications. Citeseer.
  • De, P. K., S. Mallick, B. Mukherjee, S. Sengupta, S. Pattnaik, and S. Chakraborty. 2011. Optimization of in-vitro permeation pattern of ketorolac tromethamine transdermal patches. Iranian Journal of Pharmaceutical Research 10 (2):193.
  • Diramio, J. A., W. S. Kisaalita, G. F. Majetich, and J. M. Shimkus. 2005. Poly (ethylene glycol) methacrylate/dimethacrylate hydrogels for controlled release of hydrophobic drugs. Biotechnology Progress 21 (4):1281–8. doi:10.1021/bp0495670.
  • Gils, P. S., D. Ray, and P. K. Sahoo. 2009. Characteristics of xanthan gum-based biodegradable superporous hydrogel. International Journal of Biological Macromolecules 45 (4):364–71. doi:10.1016/j.ijbiomac.2009.07.007.
  • Gulrez, S. K., S. Al-Assaf, and G. O. Phillips. 2011. Hydrogels: Methods of preparation, characterisation and applications. In Progress in molecular and environmental bioengineering-from analysis and modeling to technology applications. InTech.
  • Hamidi, M., A. Azadi, and P. Rafiei. 2008. Hydrogel nanoparticles in drug delivery. Advanced Drug Delivery Reviews 60 (15):1638–49. doi:10.1016/j.addr.2008.08.002.
  • Hobzova, R., J. Hrib, J. Sirc, E. Karpushkin, J. Michalek, O. Janouskova, and P. Gatenholm. 2018. Embedding of bacterial cellulose nanofibers within PHEMA hydrogel matrices: Tunable stiffness composites with potential for biomedical applications. Journal of Nanomaterials 2018:1–11. 2018. doi:10.1155/2018/5217095.
  • Hoffman, A. S. 2012. Hydrogels for biomedical applications. Advanced Drug Delivery Reviews 64:18–23. doi:10.1016/j.addr.2012.09.010.
  • Iza, M., G. Stoianovici, L. Viora, J. Grossiord, and G. Couarraze. 1998. Hydrogels of poly (ethylene glycol): Mechanical characterization and release of a model drug. Journal of Controlled Release 52 (1–2):41–51. doi:10.1016/S0168-3659(97)00191-0.
  • Koshy, O., L. Subramanian, and S. Thomas. 2017. Differential scanning calorimetry in nanoscience and nanotechnology. In Thermal and rheological measurement techniques for nanomaterials characterization, 109–22. Elsevier.
  • Lee, P. I. 1985. Kinetics of drug release from hydrogel matrices. Journal of Controlled Release 2:277–88. doi:10.1016/0168-3659(85)90051-3.
  • Lee, S. C., I. K. Kwon, and K. Park. 2013. Hydrogels for delivery of bioactive agents: A historical perspective. Advanced Drug Delivery Reviews 65 (1):17–20. doi:10.1016/j.addr.2012.07.015.
  • Li, J., and D. J. Mooney. 2016. Designing hydrogels for controlled drug delivery. Nature Reviews Materials 1 (12):16071. doi:10.1038/natrevmats.2016.71.
  • Lu, S., and K. S. Anseth. 1999. Photopolymerization of multilaminated poly (HEMA) hydrogels for controlled release. Journal of Controlled Release 57 (3):291–300. doi:10.1016/S0168-3659(98)00125-4.
  • Mahmoud, G. A., D. E. Hegazy, and H. Kamal. 2014. In-vitro release of ketoprofen behavior loaded in polyvinyl alcohol/acrylamide hydrogels prepared by gamma irradiation. Arab Journal of Nuclear Sciences and Applications 47 (1):28–40.
  • Metters, A., K. Anseth, and C. Bowman. 2000. Fundamental studies of a novel, biodegradable PEG-b-PLA hydrogel. Polymer 41 (11):3993–4004. doi:10.1016/S0032-3861(99)00629-1.
  • Narayanaswamy, R., and V. P. Torchilin. 2019. Hydrogels and their applications in targeted drug delivery. Molecules 24 (3):603. doi:10.3390/molecules24030603.
  • Patel, R. P., D. J. Patel, D. B. Bhimani, and J. K. Patel. 2008. Physicochemical characterization and dissolution study of solid dispersions of furosemide with polyethylene glycol 6000 and polyvinylpyrrolidone K30. Dissolution Technologies 15 (3):17–25. doi:10.14227/DT150308P17.
  • Peppas, N. A., K. B. Keys, M. Torres-Lugo, and A. M. Lowman. 1999. Poly (ethylene glycol)-containing hydrogels in drug delivery. Journal of Controlled Release 62 (1–2):81–7. doi:10.1016/S0168-3659(99)00027-9.
  • Ranjha, N. M., and J. Mudassir. 2008. Swelling and aspirin release study: Cross-linked pH-sensitive vinyl acetate-co-acrylic acid (VAC-co-AA) hydrogels. Drug Development and Industrial Pharmacy 34 (5):512–21. doi:10.1080/03639040701744079.
  • Rokhade, A. P., S. A. Agnihotri, S. A. Patil, N. N. Mallikarjuna, P. V. Kulkarni, and T. M. Aminabhavi. 2006. Semi-interpenetrating polymer network microspheres of gelatin and sodium carboxymethyl cellulose for controlled release of ketorolac tromethamine. Carbohydrate Polymers 65 (3):243–52. doi:10.1016/j.carbpol.2006.01.013.
  • Sarı, A., C. Alkan, and A. Bicer. 2012. Synthesis and thermal properties of polystyrene-graft-PEG copolymers as new kinds of solid–solid phase change materials for thermal energy storage. Materials Chemistry and Physics 133 (1):87–94. doi:10.1016/j.matchemphys.2011.12.056.
  • Satish, C., K. Satish, and H. Shivakumar. 2006. Hydrogels as controlled drug delivery systems: Synthesis, crosslinking, water and drug transport mechanism. Indian Journal of Pharmaceutical Sciences 68 (2):133–40. doi:10.4103/0250-474X.25706.
  • Serra, L., J. Doménech, and N. A. Peppas. 2006. Drug transport mechanisms and release kinetics from molecularly designed poly (acrylic acid-g-ethylene glycol) hydrogels. Biomaterials 27 (31):5440–51. doi:10.1016/j.biomaterials.2006.06.011.
  • Suhail, M., J.-Y. Liu, A. Khan, H. Ullah, M. U. Minhas, and P.-C. Wu. 2022. Fabrication, characterization and toxicological evaluation of polyethylene glycol/sodium polystyrene sulfonate hydrogels for controlled delivery of Acetaminophen. Journal of Materials Research and Technology 19:3073–87. doi:10.1016/j.jmrt.2022.06.056.
  • Tang, B., M. Qiu, and S. Zhang. 2012. Thermal conductivity enhancement of PEG/SiO2 composite PCM by in situ Cu doping. Solar Energy Materials and Solar Cells 105:242–8. doi:10.1016/j.solmat.2012.06.012.
  • Tena, A., S. Shishatskiy, and V. Filiz. 2015. Poly (ether–amide) vs. poly (ether–imide) copolymers for post-combustion membrane separation processes. RSC Advances 5 (29):22310–8. doi:10.1039/C5RA01328C.
  • Todica, M., R. Stefan, C. Pop, and L. Olar. 2015. IR and Raman investigation of some poly (acrylic) acid gels in aqueous and neutralized state. Acta Physica Polonica A 128 (1):128–35. doi:10.12693/APhysPolA.128.128.
  • Tokarev, I., and S. Minko. 2009. Stimuli-responsive hydrogel thin films. Soft Matter 5 (3):511–24. doi:10.1039/B813827C.
  • Van den Mooter, G., P. Augustijns, N. Blaton, and R. Kinget. 1998. Physico-chemical characterization of solid dispersions of temazepam with polyethylene glycol 6000 and PVP K30. International Journal of Pharmaceutics 164 (1–2):67–80. doi:10.1016/S0378-5173(97)00401-8.
  • Varaprasad, K., G. M. Raghavendra, T. Jayaramudu, M. M. Yallapu, and R. Sadiku. 2017. A mini review on hydrogels classification and recent developments in miscellaneous applications. Materials Science & Engineering. C, Materials for Biological Applications 79:958–71.
  • Vedadghavami, A., F. Minooei, M. H. Mohammadi, S. Khetani, A. Rezaei Kolahchi, S. Mashayekhan, and A. Sanati-Nezhad. 2017. Manufacturing of hydrogel biomaterials with controlled mechanical properties for tissue engineering applications. Acta Biomaterialia 62:42–63.
  • Wang, J., and W. Wu. 2005. Swelling behaviors, tensile properties and thermodynamic studies of water sorption of 2-hydroxyethyl methacrylate/epoxy methacrylate copolymeric hydrogels. European Polymer Journal 41 (5):1143–51. doi:10.1016/j.eurpolymj.2004.11.034.
  • Yarimkaya, S., and H. Basan. 2007. Swelling behavior of poly (2‐hydroxyethyl methacrylate‐co‐acrylic acid‐co‐ammonium acrylate) hydrogels. Journal of Macromolecular Science, Part A: Pure and Applied Chemistry 44 (9):939–46. doi:10.1080/10601320701424198.

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