Nano-dimensional gold synthesis for biomedical applications: upscaling and challenges

References

• Agnihotri, M., S. Joshi, A. R. Kumar, S. Zinjarde, and S. Kulkarni. 2009. Biosynthesis of gold nanoparticles by the tropical marine yeast Yarrowia lipolytica NCIM 3589. Materials Letters 63 (15):1231–4. doi:10.1016/j.matlet.2009.02.042.
   Web of Science ®Google Scholar
• Ajayan, P. M. 2004. Nanotechnology: How does a nanofibre grow? Nature 427 (6973):402–3. doi:10.1038/427402a.
   PubMed Web of Science ®Google Scholar
• Akhtar, M. S., J. Panwar, and Y. S. Yun. 2013. Biogenic synthesis of metallic nanoparticles by plant extracts. ACS Sustainable Chemistry & Engineering 1 (6):591–602. doi:10.1021/sc300118u.
   Web of Science ®Google Scholar
• Albanese, A., and W. C. W. Chan. 2011. Effect of gold nanoparticle aggregation on cell uptake and toxicity. ACS Nano 5 (7):5478–89. doi:10.1021/nn2007496.
   PubMed Web of Science ®Google Scholar
• Alkilany, A. M., S. E. Lohse, and C. J. Murphy. 2013. The gold standard: Gold nanoparticle libraries to understand the nano–bio interface. Accounts of Chemical Research 46 (3):650–61. doi:10.1021/ar300015b.
   PubMed Web of Science ®Google Scholar
• Annadhasan, M., T. Muthukumarasamyvel, V. R. Sankar Babu, and N. Rajendiran. 2014. Green synthesized silver and gold nanoparticles for colorimetric detection of Hg2+, Pb2+, and Mn2+ in aqueous medium. ACS Sustainable Chemistry & Engineering 2 (4):887–96. doi:10.1021/sc400500z.
   Web of Science ®Google Scholar
• Arvizo, R., R. Bhattacharya, and P. Mukherjee. 2010. Gold nanoparticles: Opportunities and challenges in nanomedicine. Expert Opinion on Drug Delivery 7 (6):753–63. doi:10.1517/17425241003777010.
   PubMed Web of Science ®Google Scholar
• Aydin, E., J. A. Planell, and V. Hasirci. 2011. Hydroxyapatite nanorod-reinforced biodegradable poly (Llactic acid) composites for bone plate applications. Journal of Materials Science. Materials in Medicine 22 (11):2413–27. doi:10.1007/s10856-011-4435-z.
   PubMed Web of Science ®Google Scholar
• Balasooriya, E. R., C. D. Jayasinghe, U. A. Jayawardena, R. W. D. Ruwanthika, R Mendis de Silva, and P. V. Udagama. 2017. Honey mediated green synthesis of nanoparticles: New era of safe nanotechnology. Journal of Nanomaterials 2017:1–10. doi:10.1155/2017/5919836.
   Web of Science ®Google Scholar
• Bao, C., J. Conde, E. Polo, P. del Pino, M. Moros, P. V. Baptista, V. Grazu, D. Cui, and J. M. de la Fuente. 2014. A promising road with challenges: Where are gold nanoparticles in translational research? Nanomedicine (London, England) 9 (15):2353–70. doi:10.2217/nnm.14.155.
   PubMed Web of Science ®Google Scholar
• Bashir, M. R., L. Bhatti, D. Marin, and R. C. Nelson. 2015. Emerging applications for ferumoxytol as a contrast agent in MRI. Journal of Magnetic Resonance Imaging : JMRI 41 (4):884–98. doi:10.1002/jmri.24691.
   PubMed Web of Science ®Google Scholar
• Becue, A., C. Champod, and P. Margot. 2007. Use of gold nanoparticles as molecular intermediates for the detection of fingermarks. Forensic Science International 168 (2–3):169–76. doi:10.1016/j.forsciint.2006.07.014.
   PubMed Web of Science ®Google Scholar
• Bhattacharya, R., and P. Mukherjee. 2008. Biological properties of “naked” metal nanoparticles. Advanced Drug Delivery Reviews 60 (11):1289–306. doi:10.1016/j.addr.2008.03.013.
   PubMed Web of Science ®Google Scholar
• Bhattacharyya, A., A. Bhaumik, M. Nandi, S. Viraktamath, R. Kumar, A. Nayak, M. U. Chowdhury, and S. Mandal. 2010. Nano—a new frontier in present century. Advances in Life Sciences 3 (1–4):18–23.
   Google Scholar
• Bhau, B. S., S. Ghosh, S. Puri, B. Borah, D. K. Sarmah, and R. Khan. 2015. Green synthesis of gold nanoparticles from the leaf extract of Nepenthes khasiana and antimicrobial assay. Advanced Materials Letters 6 (1):55–8. doi:10.5185/amlett.2015.5609.
   Google Scholar
• Bose, S., and B. Michniak-Kohn. 2013. Preparation and characterization of lipid based nano systems for topical delivery of quercetin. European Journal of Pharmaceutical Sciences: Official Journal of the European Federation for Pharmaceutical Sciences 48 (3):442–52. doi:10.1016/j.ejps.2012.12.005.
   PubMed Web of Science ®Google Scholar
• Bosecker, K. 1997. Bioleaching: Metal solubilization by microorganisms. FEMS Microbiology Reviews 20 (3–4):591–604. doi:10.1111/j.1574-6976.1997.tb00340.x.
   Web of Science ®Google Scholar
• Brannon-Peppas, L., and J. O. Blanchette. 2004. Nanoparticle and targeted systems for cancer therapy. Advanced Drug Delivery Reviews 56 (11):1649–59. doi:10.1016/j.addr.2004.02.014.
   PubMed Web of Science ®Google Scholar
• Burda, C., S. Link, M. Mohamed, and M. El-Sayed. 2001. The relaxation pathways of CdSe nanoparticles monitored with femtosecond time-resolution from the visible to the IR: Assignment of the transient features by carrier quenching. The Journal of Physical Chemistry B 105 (49):12286–92. 10.1021/jp0124589.
   Web of Science ®Google Scholar
• Buzea, C., I. I. Pacheco, and K. Robbie. 2007. Nanomaterials and nanoparticles: Sources and toxicity. Biointerphases 2 (4):MR17–MR71. doi:10.1116/1.2815690.
   PubMed Web of Science ®Google Scholar
• Charcosset, C., and H. Fessi. 2005. A new process for drug loaded nano capsules preparation using a membrane contactor. Drug Development and Industrial Pharmacy 31 (10):987–92. doi: 10.1080/03639040500306237.
   PubMed Web of Science ®Google Scholar
• Chen, Y., X. Gu, C. G. Nie, Z. Y. Jiang, Z. X. Xie, and Z. J. Lin. 2005. Shape controlled growth of gold nanoparticles by a solution synthesis. Chemical Communications 33 (33):4181–3. doi:10.1039/b504911c.
   Google Scholar
• Chen, Y., and F. Xun. 2022. Gold nanoparticles for skin drug delivery. International Journal of Pharmaceutics 625 (625):122122. doi:10.1016/j.ijpharm.2022.122122.
   PubMedGoogle Scholar
• Colombo, A. P., S. Briancon, J. Lieto, and H. Fessi. 2001. Project, design, and use of a pilot plant for nano capsule production. Drug Development and Industrial Pharmacy 27 (10):1063–72. doi:10.1081/DDC-100108369.
   PubMed Web of Science ®Google Scholar
• Corrias, F., and F. Lai. 2011. New methods for lipid nanoparticles preparation. Recent Patents on Drug Delivery & Formulation 5 (3):201–13. doi:10.2174/187221111797200597.
   PubMedGoogle Scholar
• Daisy, P., and K. Saipriya. 2012. Biochemical analysis of Cassia fistula aqueous extract and phytochemically synthesized gold nanoparticles as hypoglycemic treatment for diabetes mellitus. International Journal of Nanomedicine 7:1189–202. doi:10.2147/IJN.S26650.
   PubMed Web of Science ®Google Scholar
• Daniel, M. C., and D. Astruc. 2004. Gold nanoparticles: Assembly, supramolecular chemistry, quantum-size related properties and applications toward biology, catalysis and nanotechnology. Chemical Reviews 104 (1):293–346. doi:10.1021/cr030698+.
   PubMed Web of Science ®Google Scholar
• Das, R. K., N. Gogoi, and U. Bora. 2011. Green synthesis of gold nanoparticles using Nyctanthes arbortristis flower extract. Bioprocess and Biosystems Engineering 34 (5):615–9. doi:10.1007/s00449-010-0510-y.
   PubMed Web of Science ®Google Scholar
• Das, S., A. Halder, S. Mandal, M. Mazumder, T. Bera, A. Mukherjee, and P. Roy. 2018. Andrographolide engineered gold nanoparticle to overcome drug resistant visceral leishmaniasis. Artificial Cells, Nanomedicine, and Biotechnology 46 (sup1):751–62. doi:10.1080/21691401.2018.1435549.
   PubMed Web of Science ®Google Scholar
• De Jong, H, and Borm Paul, J. A. 2008. Drug delivery and nanoparticles: Applications and hazards. International Journal of Nanomedicine 3 (2):133–49. doi:10.2147/ijn.s596.
   PubMed Web of Science ®Google Scholar
• Divya, M. J., C. Sowmia, K. Joona, and K. P. Dhanya. 2013. Synthesis of zinc oxide nanoparticle from Hibiscus rosasinensis leaf extract and investigation of its antimicrobial activity. Research Journal of Pharmaceutical, Biological and Chemical Sciences 4:1137–42.
   Google Scholar
• Dong, H., F. Zou, X. Hu, H. Zhu, K. Koh, and H. Chen. 2018. Analyte induced AuNPs aggregation enhanced surface plasmon resonance for sensitive detection of paraquat. Biosensors & Bioelectronics 117:605–12. doi:10.1016/j.bios.2018.06.057.
   PubMed Web of Science ®Google Scholar
• Du, L., H. Jiang, X. Liu, and E. Wang. 2007. Biosynthesis of gold nanoparticles assisted by Escherichia coli DH5α and its application on direct electrochemistry of hemoglobin. Electrochemistry Communications 9 (5):1165–70. doi:10.1016/j.elecom.2007.01.007.
   Web of Science ®Google Scholar
• Elahi, N., M. Kamali, and M. H. Baghersad. 2018. Recent biomedical applications of gold nanoparticles: A review. Talanta 184:537–56. doi:10.1016/j.talanta.2018.02.088.
   PubMed Web of Science ®Google Scholar
• El-Harati, A. A., C. Charcosset, and H. Fessi. 2006. Influence of the formulation for solid lipid nanoparticles prepared with a membrane contactor. Pharmaceutical Development and Technology 11 (2):153–7. doi:10.1080/10837450600561182.
   PubMed Web of Science ®Google Scholar
• El-Sayed, M. A. 2001. Some interesting properties of metals confined in time and nanometer space of different shapes. Accounts of Chemical Research 34 (4):257–64. doi:10.1021/ar960016n.
   PubMed Web of Science ®Google Scholar
• Engelmann, W., and R. Von Hohendorff. 2019. Regulatory challenges in nanotechnology for sustainable production of biofuel in Brazil. In Sustainable bioenergy, 367–81. Amsterdam, The Netherlands: Elsevier. doi:10.1016/B978-0-12-817654-2.00014-9.
   Google Scholar
• Eustis, S., and A. El-Sayed. 2006. Why Gold Nanoparticles are more precious than pretty gold: Noble metal surface plasmon resonance and its enhancement of the radiative and nonradiative properties of nanocrystals of different shapes. Chemical Society Reviews 35 (3):209–17. doi:10.1039/B514191E.
   PubMed Web of Science ®Google Scholar
• Fang, G., Y. Yang, J. Yao, Z. Shao, and X. Chen. 2016. Formation of different gold nanostructures by silk nanofibrils. Materials Science & Engineering. C, Materials for Biological Applications 64:376–82. doi:10.1016/j.msec.2016.03.113.
   PubMed Web of Science ®Google Scholar
• Faraday, M. 1857. The Bakerian Lecture: Experimental relations of gold to light. Philosophical Transactions of the Royal Society of London 147:145–81. doi:10.1098/rstl.1857.0011.
   Google Scholar
• Fessi, H., F. Puisieux, J. Devissaguet, N. Ammoury, and S. Benita. 1989. Nanocapsule formation by interfacial polymer deposition following solvent displacement. International Journal of Pharmaceutics 55 (1):R1–4. doi:10.1016/0378-5173(89)90281-0.
   Web of Science ®Google Scholar
• Figueroa, E. R., A. Y. Lin, J. Yan, L. Luo, A. E. Foster, and R. A. Drezek. 2014. Optimization of PAMAM-gold nanoparticle conjugation for gene therapy. Biomaterials 35 (5):1725–34. doi:10.1016/j.biomaterials.2013.11.026.
   PubMed Web of Science ®Google Scholar
• Frank, C. 1999. Gold Based Therapeutic agents. Chemical Reviews 99 (9):2589–600. doi:10.1021/cr980431o.
   PubMed Web of Science ®Google Scholar
• Gerber, A., M. Bundschuh, D. Klingelhofer, and D. A. Groneberg. 2013. Gold nanoparticles: Recent aspects for human toxicology. Journal of Occupational Medicine and Toxicology (London, England) 8 (1):32–6. doi:10.1186/1745-6673-8-32.
   PubMedGoogle Scholar
• Ghosh, S. K., and T. Pal. 2007. Interparticle coupling effect on the surface plasmon resonance of gold nanoparticles: From theory to applications. Chemical Reviews 107 (11):4797–862. doi:10.1021/cr0680282.
   PubMed Web of Science ®Google Scholar
• Ghosh, P. S., C. K. Kim, G. Han, N. S. Forbes, and V. M. Rotello. 2008. Efficient gene delivery vectors by tuning the surface charge density of amino acid-functionalized gold nanoparticles. ACS Nano 2 (11):2213–8. doi:10.1021/nn800507t.
   PubMed Web of Science ®Google Scholar
• Ghosh, S., S. Patil, M. Ahire, R. Kitture, D. Gurav, A. M. Jabgunde, S. Kale, K. Pardesi, V. Shinde, V. Bellare, et al. 2012. Gnidia glauca flower extract mediated synthesis of gold nanoparticles and evaluation of its chemocatalytic potential. Journal of Nanobiotechnology 10:17. doi:10.1186/1477-3155-10-17.
   PubMed Web of Science ®Google Scholar
• Ghule, K., A. V. Ghule, J. Y. Liu, and Y. C. Ling. 2006. Microscale size triangular gold prisms synthesized using Bengal gram beans (Cicer arietinum L.) extract and HAuCl4.3.H2O: A green biogenic approach. Journal of Nanoscience and Nanotechnology 6 (12):3746–51. doi:10.1166/jnn.2006.608.
   PubMed Web of Science ®Google Scholar
• Gole, A., and C. J. Murphy. 2004. Seed mediated synthesis of gold nanorods: Role of the size and nature of seed. Chemistry of Materials 16 (19):3633–40. doi:10.1021/cm0492336.
   Web of Science ®Google Scholar
• Gomez, L., V. Sebastian, S. Irusta, A. Ibarra, M. Arruebo, and J. Santamaria. 2014. Scaled-up production of plasmonic nanoparticles using microfluidics: From metal precursors to functionalized and sterilized nanoparticles. Lab on a Chip 14 (2):325–32. doi:10.1039/c3lc50999k.
   PubMed Web of Science ®Google Scholar
• Goodman, C., C. McCusker, T. Yilmaz, and V. M. Rotello. 2004. Toxicity of gold nanoparticles functionalized with cationic and anionic side chains. Bioconjugate Chemistry 15 (4):897–900. doi:10.1021/bc049951i.
   PubMed Web of Science ®Google Scholar
• Halder, A., S. Das, D. Ojha, D. Chattopadhyay, and A. Mukherjee. 2018. Highly monodispersed gold nanoparticles synthesis and inhibition of herpes simplex virus infections. Materials Science & Engineering. C, Materials for Biological Applications 89:413–21. doi:10.1016/j.msec.2018.04.005.
   PubMed Web of Science ®Google Scholar
• Han, G., P. Ghosh, and V. M. Rotello. 2007. Functionalized gold nanoparticles for drug delivery. Nanomedicine 2 (1):113–23. doi:10.2217/17435889.2.1.113.
   PubMed Web of Science ®Google Scholar
• Hayat, M. 1989. Colloidal gold: Principles, methods and applications. San Diego, CA: Academic.
   Google Scholar
• Her, S., A. D. Jaffray, and C. Allen. 2017. Gold nanoparticles for applications in cancer radiotherapy: Mechanisms and recent advancements. Advanced Drug Delivery Reviews 109:84–101. doi:10.1016/j.addr.2015.12.012.
   PubMed Web of Science ®Google Scholar
• Horikoshi, S., and N. Serpone. 2013. Introduction to nanotechnology, 1–24. London: Wiley-VCH Verlag GmbH & Co. KGaA.
   Google Scholar
• Hosny, M., A. S. Eltaweil, M. Mostafa, Y. A. El-Badry, E. E. Hussein, A. M. Omer, and M. Fawzy. 2022. Facile synthesis of gold nanoparticles for anticancer, antioxidant applications, and photocatalytic degradation of toxic organic pollutants. ACS Omega 7 (3):3121–33. doi:10.1021/acsomega.1c06714.
   PubMed Web of Science ®Google Scholar
• Hosny, M., M. Fawzy, A. M. Abdelfatah, E. E. Fawzy, and A. S. Eltaweil. 2021. Comparative study on the potentialities of two halophytic species in the green synthesis of gold nanoparticles and their anticancer, antioxidant and catalytic efficiencies. Advanced Powder Technology 32 (9):3220–33. doi doi:10.1016/j.apt.2021.07.008.
   Web of Science ®Google Scholar
• Hosny, M., M. Fawzy, Y. A. El-Badry, E. E. Hussein, and A. S. Eltaweil. 2022. Plant-assisted synthesis of gold nanoparticles for photocatalytic, anticancer, and antioxidant applications. Journal of Saudi Chemical Society 26 (2):101419. doi:10.1016/j.jscs.2022.101419.
   Web of Science ®Google Scholar
• Huang, D., F. Liao, S. Molesa, D. Redinger, and V. Subramanian. 2003. Plastic-compatible low resistance printable gold nanoparticle conductors for flexible electronics. Journal of the Electrochemical Society 150 (7):G412–417. doi:10.1149/1.1582466.
   Web of Science ®Google Scholar
• Hughes, G. A. 2005. Nanostructure-mediated drug delivery. Nanomedicine : Nanotechnology,Biology, and Medicine 1 (1):22–30. doi:10.1016/j.nano.2004.11.009.
   PubMed Web of Science ®Google Scholar
• Hussain, M. S., S. Fareed, S. Ansari, M. A. Rahman, I. Z. Ahmad, and M. Saeed. 2012. Current approaches toward production of secondary plant metabolites. Journal of Pharmacy & Bioallied Sciences 4 (1):10–20. doi:10.4103/0975-7406.92725.
   PubMedGoogle Scholar
• Hutchison, J. E. 2008. Greener nanoscience: A proactive approach to advancing applications and reducing implications of nanotechnology. ACS Nano 2 (3):395–402. doi:10.1021/nn800131j.
   PubMed Web of Science ®Google Scholar
• Ibrahim, A., P. B. Oldham, D. L. Stokes, and T. Vo-Dinh. 1996. Determination of enhancement factors for surface-enhanced FT-Raman spectroscopy on gold and silver surfaces. Journal of Raman Spectroscopy 27 (12):887–91. doi:10.1002/(sici)1097-4555(199612)27:12<887::aid-jrs46>3.0.co;2-2.
   Web of Science ®Google Scholar
• Iravani, S. 2011. Green synthesis of metal nanoparticles using plants. Green Chemistry 13 (10):2638–50. doi:10.1039/c1gc15386b.
   Web of Science ®Google Scholar
• Jagannathan, R., P. Poddar, and A. Prabhune. 2007. Cephalexin mediated synthesis of Quasi- spherical and anisotropic gold nanoparticles and their in situ capping by the antibiotic. The Journal of Physical Chemistry C 111 (19):6933–8. doi:10.1021/jp067645r.
   Web of Science ®Google Scholar
• Jai Poinern, G. E., P. Chapman, X. Le, and D. Fawcett. 2013. Green biosynthesis of gold nanometer scale plates using the leaf extracts from an indigenous Australian plant Eucalyptus macrocarpa. Gold Bulletin 46 (3):165–73. doi:10.1007/s13404-013-0096-7.
   Web of Science ®Google Scholar
• Jain, K. K. 2005. Nanotechnology-based lab-on-achip devices. In Encyclopedia of diagnostic genomics and proteomics, 891–5. New York: Marcel Dekkar Inc.
   Google Scholar
• Jayaseelan, C., R. Ramkumar, A. Rahuman, and P. Perumal. 2013. Green synthesis of gold nanoparticles using seed aqueous extract of Abelmoschus esculentus and its antifungal activity. Industrial Crops and Products 45:423–9. doi:10.1016/j.indcrop.2012.12.019.
   Web of Science ®Google Scholar
• Joshi, P., V. Shewale, R. Pandey, V. Shanker, S. Hussain, and S. P. Karna. 2011. Tryptophan-gold nanoparticle interaction: A first-principles Quantum mechanical study. The Journal of Physical Chemistry C 115 (46):22818–26. doi:10.1021/jp2070437.
   Web of Science ®Google Scholar
• Junghanns, J. A. H., and R. H. Müller. 2008. Nanocrystal technology, drug delivery and clinical applications. International Journal of Nanomedicine 3 (3):295–309. doi:10.2147/ijn.s595.
   PubMed Web of Science ®Google Scholar
• Kakkar, V., and I. P. Kaur. 2012. Preparation, characterization and scale-up of sesamol loaded solid lipid nanoparticles. Nanotechnology Development 2 (1):e8–e8. doi:10.4081/nd.2012.e8.
   Google Scholar
• Karuppiah, C., S. Palanisamy, S.-M. Chen, R. Emmanue, K. Muthupandi, and P. Prakash. 2015. Green synthesis of gold nanoparticles and its application for the trace level determination of painter’s colic. RSC Advances 5 (21):16284–91. doi:10.1039/C4RA14988B.
   Web of Science ®Google Scholar
• Kemp, M. M., A. Kumar, S. Mousa, T. J. Park, P. Ajayan, N. Kubotera, S. A. Mousa, and R. A. Linhardt. 2009. Synthesis of gold and silver nanoparticles stabilized with glycosaminoglycan’s having distinct biological activities. Biomacromolecules 10 (3):589–95. doi:10.1021/bm801266t.
   PubMed Web of Science ®Google Scholar
• Khalil, M. M. H., E. H. Ismail, and F. El-Magdoub. 2012. Biosynthesis of Au nanoparticles using olive leaf extract. Arabian Journal of Chemistry 5 (4):431–7. doi:10.1016/j.arabjc.2010.11.011.
   Web of Science ®Google Scholar
• Khan, A. K., R. Rashid, G. Murtaza, and A. Zahra. 2014. Gold nanoparticles synthesis and applications in drug delivery. Tropical Journal of Pharmaceutical Research 13 (7):1169–77. doi:10.4314/tjpr.v13i7.23.
   Web of Science ®Google Scholar
• Kharlamov, A. N., and J. L. Gabinsky. 2012. Plasmonic photothermic and stem cell therapy of atherosclerotic plaque as a novel nanotool for angioplasty and artery remodeling. Rejuvenation Research 15 (2):222–30. doi:10.1089/rej.2011.1305.
   PubMed Web of Science ®Google Scholar
• Kharlamov, A. N., A. E. Tyurnina, V. S. Veselova, O. P. Kovtun, V. Y. Shur, and J. L. Gabinsky. 2015. Silica-gold nanoparticles for athero protective management of plaques: Results of the NANOM-FIM trial. Nanoscale 7 (17):8003–15. doi:10.1039/c5nr01050k.
   PubMed Web of Science ®Google Scholar
• Kim, B., S. L. Tripp, and A. Wei. 2001. Self-organization of large gold nanoparticle arrays. Journal of the American Chemical Society 123 (32):7955–6. doi:10.1021/ja0160344.
   PubMed Web of Science ®Google Scholar
• Kobayashi, Y., H. Inose, R. Nagasu, T. Nakagawa, Y. Kubota, K. Gonda, and N. Ohuchi. 2013. X-ray imaging technique using colloid solution of Au/silica/poly(ethylene glycol) nanoparticles. Materials Research Innovations 17 (7):507–14. doi:10.1179/1433075X13Y.0000000100.
   Web of Science ®Google Scholar
• Kobayashi, Y., H. Matsudo, T. Li, K. Shibuya, Y. Kubota, T. Oikawa, T. Nakagawa, and K. Gonda. 2016. Fabrication of quantum dot/silica core-shell particles immobilizing Au nanoparticles and their dual imaging functions. Applied Nanoscience 6 (3):301–7. doi:10.1007/s13204-015-0440-8.
   Web of Science ®Google Scholar
• Koch, C. C. 2003. Top-down synthesis of nanostructured materials; mechanical and thermal processing methods. Reviews on Advanced Materials Science 5:91–9. ISSN 1606–5131
   Web of Science ®Google Scholar
• Kou, J., and R. S. Varma. 2012. Beet juice-induced green fabrication of plasmonic AgCl/Ag nanoparticles. ChemSusChem 5 (12):2435–41. doi:10.1002/cssc.201200477.
   PubMed Web of Science ®Google Scholar
• Kreuter, J. 1994. Nanoparticles. In Colloidal drug delivery systems, 219–342. New York: Marcel Dekker.
   Google Scholar
• Kruis, F. E., H. Fissan, and A. Peled. 1998. Synthesis of nanoparticles in the gas phase for electronic, optical and magnetic applications–a review. Journal of Aerosol Science 29 (5-6):511–35. doi:10.1016/S0021-8502(97)10032-5.
   Web of Science ®Google Scholar
• Kumar, S., K. S. Gandhi, and R. Kumar. 2007. Modeling of formation of gold nanoparticles by citrate method. Industrial & Engineering Chemistry Research 46 (10):3128–36. doi:10.1021/ie060672j.
   Web of Science ®Google Scholar
• Ladj, R., A. Bitar, M. M. Eissa, H. Fessi, Y. Mugnier, R. Le Dantec, and A. Elaissari. 2013. Polymer encapsulation of inorganic nanoparticles for biomedical applications. International Journal of Pharmaceutics 458 (1):230–41. doi:10.1016/j.ijpharm.2013.09.00.
   PubMed Web of Science ®Google Scholar
• Lamprecht, A., N. Ubrich, M. Hombreiro Pérez, C. Lehr, M. Hoffman, and P. Maincent. 1999. Biodegradable mono dispersed nanoparticles prepared by pressure homogenization emulsification. International Journal of Pharmaceutics 184 (1):97–105. doi:10.1016/S0378-5173(99)00107-6.
   PubMed Web of Science ®Google Scholar
• Langer, R. 1998. Drug delivery and targeting. Nature 392 (6679 Suppl):5–10.
   PubMed Web of Science ®Google Scholar
• Lehner, R., X. Wang, S. Marsch, and P. Hunziker. 2013. Intelligent nanomaterials for medicine: Carrier platforms and targeting strategies in the context of clinical application. Nanomedicine : nanotechnology, Biology, and Medicine 9 (6):742–57. doi:10.1016/j.nano.2013.01.012.
   PubMed Web of Science ®Google Scholar
• Li, J. F., Y. F. Huang, Y. Ding, Z. L. Yang, S. B. Li, X. S. Zhou, F. R. Fan, W. Zhang, Z. Y. Zhou, D. Y. Wu, et al. 2010. Shell-isolated nanoparticle-enhanced Raman spectroscopy. Nature 464 (7287):392–5. doi:10.1038/nature08907.
   PubMed Web of Science ®Google Scholar
• Link, S., and M. A. El Sayed. 2003. Optical properties and ultrafast dynamics of metallic nanocrystals. Annual Review of Physical Chemistry 54:331–66. doi:10.1146/annurev.physchem.54.011002.103759.
   PubMed Web of Science ®Google Scholar
• Link, S., and M. A. El-Sayed. 1999. Spectral properties and relaxation dynamics of surface plasmon electronic oscillations in gold and silver nanodots and nanorods. The Journal of Physical Chemistry B 103 (40):8410–26. doi:10.1021/jp9917648.
   Web of Science ®Google Scholar
• Liu, X., N. Huang, H. Li, Q. Jin, and J. Ji. 2013. Surface and size effects on cell interaction of gold nanoparticles with both phagocytic and nonphagocytic cells. Langmuir : The ACS Journal of Surfaces and Colloids 29 (29):9138–48. doi:10.1021/la401556k.
   PubMed Web of Science ®Google Scholar
• Liu, B., J. Xie, J. Y. Lee, Y. P. Ting, and J. Paul Chen. 2005. Optimization of high-yield biological synthesis of single crystalline gold nanoplates. The Journal of Physical Chemistry. B 109 (32):15256–63. doi:10.1021/jp051449n.
   PubMed Web of Science ®Google Scholar
• Li, L., and J. Weng. 2010. Enzymatic synthesis of gold nanoflowers with trypsin. Nanotechnology 21 (30):305603. doi:10.1088/0957-4484/21/30/305603.
   PubMed Web of Science ®Google Scholar
• Mal, S., T. Saha, A. Halder, K. S. Paidesetty, S. Das, W. Wui, U. Chatterji, and P. Roy. 2023. EGF-conjugated bio-safe luteolin gold nanoparticles induce cellular toxicity and cell death mediated by site-specific rapid uptake in human triple negative breast cancer cells. Journal of Drug Delivery Science and Technology 80:104148. doi:10.1016/j.jddst.2022.104148.
   Web of Science ®Google Scholar
• Masala, O., and R. Seshadri. 2004. Synthesis routes for large volumes of nanoparticles. Annual Review of Materials Research 34 (1):41–81. doi:10.1146/annurev.matsci.34.052803.090949.
   Google Scholar
• Miftahurrahman, G., H. Setiarahayu, and A. Nandiyanto. 2019. An economic evaluation on scaling-up production of nano gold from laboratory to industrial scale. Indonesian Journal of Computing, Engineering and Design (IJoCED) 1 (1):29–36. doi:10.35806/ijoced.v1i1.34.
   Google Scholar
• Murphy, C. J., A. M. Gole, J. W. Stone, P. N. Sisco, A. M. Alkilany, E. C. Goldsmith, and S. C. Baxter. 2008. Gold nanoparticles in biology: Beyond toxicity to cellular imaging. Accounts of Chemical Research 41 (12):1721–30. doi:10.1021/ar800035u.
   PubMed Web of Science ®Google Scholar
• Muthu, M. S., C. V. Rajesh, A. Mishra, and S. Singh. 2009. Stimulus-responsive targeted nanomicelles for effective cancer therapy. Nanomedicine (London, England) 4 (6):657–67. doi:10.2217/nnm.09.44.
   PubMed Web of Science ®Google Scholar
• Nagata, Y., Y. Mizukoshi, K. Okitsu, and Y. Maeda. 1996. Sono chemical formation of gold particles in aqueous solution. Radiation Research 146 (3):333–8. doi:10.2307/3579465.
   PubMed Web of Science ®Google Scholar
• Nativo, P., I. A. Prior, and M. Brust. 2008. Uptake and intracellular fate of surface-modified gold nanoparticles. ACS Nano 2 (8):1639–44. doi:10.1021/nn800330a.
   PubMed Web of Science ®Google Scholar
• Nel, A., T. Xia, L. Madler, and N. Li. 2006. Toxic potential of materials at the nano level. Science (New York, N.Y.) 311 (5761):622–7. doi:10.1126/science.1114397.
   PubMed Web of Science ®Google Scholar
• Noruzi, M., D. Zare, K. Khoshnevisan, and D. Davoodi. 2011. Rapid green synthesis of gold nanoparticles using Rosa hybrida petal extract at room temperature. Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy 79 (5):1461–5. doi:10.1016/j.saa.2011.05.001.
   PubMed Web of Science ®Google Scholar
• Oberdorster, G. 2010. Safety assessment for nanotechnology and nanomedicine: Concepts of nanotoxicology. Journal of Internal Medicine 267:89–105. doi:10.1111/j.1365-2796.2009.02187.x.
   PubMed Web of Science ®Google Scholar
• Okitsu, K., M. Ashokkumar, and F. Grieser. 2005. Sonochemical synthesis of gold nanoparticles: Effects of ultrasound frequency. The Journal of Physical Chemistry. B 109 (44):20673–5. doi:10.1021/jp0549374.
   PubMed Web of Science ®Google Scholar
• Pan, X., and R. J. Lee. 2004. Tumour-selective drug delivery via folate receptor-targeted liposomes. Expert Opinion on Drug Delivery 1 (1):7–17. doi:10.1517/17425247.1.1.7.
   PubMedGoogle Scholar
• Papavassiliou, G. C. 1979. Optical properties of small inorganic and organic metal particles. Progress in Solid State Chemistry 12 (3–4):185–271. doi:10.1016/0079-6786(79)90001-3.
   Web of Science ®Google Scholar
• Patra, S., S. Mukherjee, A. K. Barui, A. Ganguly, B. Sreedhar, and C. R. Patra. 2015. Green synthesis characterization of gold and silver nanoparticles and their potential application for cancer therapeutics. Materials Science & Engineering. C, Materials for Biological Applications 53 (53):298–309. doi:10.1016/j.msec.2015.04.048.
   PubMedGoogle Scholar
• Paviolo, C., and P. R. Stoddart. 2017. Gold nanoparticles for modulating neuronal behavior. Nanomaterials 7 (4):92. doi:10.3390/nano7040092.
   Web of Science ®Google Scholar
• Pender, D. S., L. M. Vangala, V. D. Badwaik, H. Thompson, R. Paripelly, and R. Dakshinamurthy. 2013. A New class of gold nanoantibitoics- direct coating of ampicillin on gold nanoparticles. Pharmaceutical Nanotechnology 1 (2):126–35. doi:10.2174/2211738511301020008.
   Google Scholar
• Pennemann, H., V. Hessel, and H. Löwe. 2004. Chemical microprocess technology—from laboratory-scale to production. Chemical Engineering Science 59 (22–23):4789–94. doi:10.1016/j.ces.2004.07.049.
   Web of Science ®Google Scholar
• Pessina, F., and D. Spitzer. 2017. The longstanding challenge of the nanocrystallization of 1,3,5-trinitroperhydro-1,3,5-triazine (RDX). Beilstein Journal of Nanotechnology 8:452–66. doi:10.3762/bjnano.8.49.
   PubMed Web of Science ®Google Scholar
• Petschacher, C., A. Eitzlmayr, M. Besenhard, J. Wagner, J. Barthelmes, A. Bernkop-Schnürch, J. G. Khinast, and A. Zimmer. 2013. Thinking continuously: A microreactor for the production and scale-up of biodegradable, self-assembled nanoparticles. Polymer Chemistry 4 (7):2342–52. doi:10.1039/c3py20939c.
   Web of Science ®Google Scholar
• Porta, R., M. Benaglia, and A. Puglisi. 2016. Flow chemistry: Recent developments in the synthesis of pharmaceutical products. Organic Process Research & Development 20 (1):2–25. doi:10.1021/acs.oprd.5b00325.
   Web of Science ®Google Scholar
• Pottier, A., E. Borghi, and L. Levy. 2014. New use of metals as nanosized radioenhancers. Anticancer Research 34 (1B):443–53.
   PubMed Web of Science ®Google Scholar
• Prasad, B. L. V., S. I. Stoeva, C. M. Sorensen, and K. J. Klabunde. 2003. Digestive ripening agents for gold nanoparticles: Alternatives to thiols. Chemistry of Materials 15 (4):935–42. doi:10.1021/cm0206439.
   Web of Science ®Google Scholar
• Ragelle, H., F. Danhier, V. Préat, R. Langer, and D. G. Anderson. 2017. Nanoparticle-based drug delivery systems: A commercial and regulatory outlook as the field matures. Expert Opinion on Drug Delivery 14 (7):851–64. doi:10.1080/17425247.2016.1244187.
   PubMed Web of Science ®Google Scholar
• Ramesh, P., A. Rajendran, and M. Sundaram. 2014. Green synthesis of zinc oxide nanoparticles using flower extract Cassia auriculata. Journal of NanoScience and NanoTechnology 2:41–5.
   Google Scholar
• Ranjan, A. P., A. Mukerjee, L. Helson, and J. K. Vishwanatha. 2012. Scale up, optimization and stability analysis of Curcumin C3 complex-loaded nanoparticles for cancer therapy. Journal of Nanobiotechnology 10 (1):1–18. doi:10.1186/1477-3155-10-38.
   PubMedGoogle Scholar
• Rojo, J., V. Díaz, J. M. de la Fuente, I. Segura, A. G. Barrientos, H. H. Riese, A. Bernad, and S. Penadés. 2004. Gold glyconanoparticles as new tools in antiadhesive therapy. Chembiochem: a European Journal of Chemical Biology 5 (3):291–7. doi:10.1002/cbic.200300726.
   PubMed Web of Science ®Google Scholar
• Salameh, S., J. Gómez-Hernández, A. Goulas, H. Van Bui, and J. R. van Ommen. 2017. Advances in scalable gas-phase manufacturing and processing of nanostructured solids: A review. Particuology 30:15–39. doi:10.1016/j.partic.2016.07.003.
   Web of Science ®Google Scholar
• Sanders, M. 2000. A review of controlled clinical trials examining the effects of antimalarial compounds and gold compounds on radiographic progression in rheumatoid arthritis. The Journal of Rheumatology 27 (2):523–9.
   PubMed Web of Science ®Google Scholar
• Saraf, S. 2009. Process optimization for the production of nanoparticles for drug delivery applications. Expert Opinion on Drug Delivery 6 (2):187–96. doi:10.1517/17425240902735806.
   PubMed Web of Science ®Google Scholar
• Sardar, R., A. M. Funston, P. Mulvaney, and R. W. Murray. 2009. Gold nanoparticles: Past, present, and future. Langmuir : The ACS Journal of Surfaces and Colloids 25 (24):13840–51. doi:10.1021/la9019475.
   PubMed Web of Science ®Google Scholar
• Sau, T. K., A. Pal, N. R. Jana, Z. L. Wang, and T. Pal. 2001. Size controlled synthesis of gold nanoparticles using photochemically prepared seed particles. Journal of Nanoparticle Research 3 (4):257–61. doi:10.1023/A:1017567225071.
   Web of Science ®Google Scholar
• Shao, Y., Y. Jin, and S. Dong. 2004. Synthesis of gold nanoplates by aspartate reduction of gold chloride. Chemical Communications 9 (9):1104–5. doi:10.1039/b315732f.
   Google Scholar
• Sharma, N., A. K. Pinnaka, M. Raje, A. Fnu, M. S. Bhattacharyya, and A. R. Choudhury. 2012. Exploitation of marine bacteria for production of gold nanoparticles. Microbial Cell Factories 11:86. doi:10.1186/1475-2859-11-86.
   PubMed Web of Science ®Google Scholar
• Shi, J., A. R. Votruba, O. C. Farokhzad, and R. Langer. 2010. Nanotechnology in drug delivery and tissue engineering. From discovery to applications. Nano Letters 10 (9):3223–30. doi:10.1021/nl102184c.
   PubMed Web of Science ®Google Scholar
• Shivaji, S., S. Madhu, and S. Singh. 2011. Extracellular synthesis of antibacterial silver nanoparticles using psychrophilic bacteria. Process Biochemistry 46 (9):1800–7. doi:10.1016/j.procbio.2011.06.008.
   Web of Science ®Google Scholar
• Shivananda, C. S., S. Asha, R. Madhukumar, S. Satish, B. Narayana, K. Byrappa, Y. Wang, and Y. Sangappa. 2016a. Bio-synthesis of colloidal nanoparticles: Their characterization and antibacterial activity. Biomedical Physics & Engineering Express 2 (3):035004. doi:10.1088/2057-1976/2/3/035004.
   Web of Science ®Google Scholar
• Smitha, S. L., D. Philip, and K. G. Gopchandran. 2009. Green synthesis of gold nanoparticles using Cinnamomum zeylanicum leaf broth. Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy 74 (3):735–9. doi:10.1016/j.saa.2009.08.007.
   PubMed Web of Science ®Google Scholar
• Song, Y., J. Hormes, and C. S. S. R. Kumar. 2008. Microfluidics synthesis of nanomaterials. Small 4 (6):698–711.
   PubMed Web of Science ®Google Scholar
• Stewart, B. W., and A. S. Coates. 2005. Cancer prevention: A global perspective. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology 23 (2):392–403. doi:10.1200/jco.2005.05.132.
   PubMed Web of Science ®Google Scholar
• Stylianopoulos, T., K. Soteriou, D. Fukumura, and R. K. Jain. 2013. Cationic nanoparticle shave superior trans vascular flux into solid tumors: Insights from a mathematical model. Annals of Biomedical Engineering 41 (1):68–77. doi:10.1007/s10439-012-0630-4.
   PubMed Web of Science ®Google Scholar
• Svenson, S. 2014. What nanomedicine in the clinic right now really forms nanoparticles? Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology 6 (2):125–35. doi:10.1002/wnan.1257.
   PubMed Web of Science ®Google Scholar
• Sykes, E. A., J. Chen, G. Zheng, and W. C. W. Chan. 2014. Investigating the impact of nanoparticle size on active and passive tumor targeting efficiency. ACS Nano 8 (6):5696–706. doi:10.1021/nn500299p.
   PubMed Web of Science ®Google Scholar
• Thiesen, B., and A. Jordan. 2008. Clinical applications of magnetic nanoparticles for hyperthermia. International Journal of Hyperthermia: The Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 24 (6):467–74. doi:10.1080/02656730802104757.
   PubMed Web of Science ®Google Scholar
• Tomić, S., J. Ðokić, S. Vasilijić, N. Ogrinc, R. Rudolf, P. Pelicon, D. Vučević, P. Milosavljević, S. Janković, I. Anžel, et al. 2014. Size-dependent effects of gold nanoparticles uptake on maturation and antitumor functions of human dendritic cells in vitro. PloS One 9 (5):e96584. doi:10.1371/journal.pone.0096584.
   PubMed Web of Science ®Google Scholar
• Tozawa, T. 2004. Dendron-grafted sulfur-terminated phenyleneethynylene molecular rods and blue luminescence self-assembly with Au nanoparticles. Chemical Communications (17):1904–5. doi:10.1039/B404010D.
   PubMed Web of Science ®Google Scholar
• Trotta, M., F. Debernardi, and O. Caputo. 2003. Preparation of solid lipid nanoparticles by a solvent emulsification-diffusion technique. International Journal of Pharmaceutics 257 (1–2):153–60. doi:10.1016/S0378-5173(03)00135-2.
   PubMed Web of Science ®Google Scholar
• Tsuzuki, T., and P. G. McCormick. 2004. Mechanochemical synthesis of nanoparticles. Journal of Materials Science 39 (16/17):5143–6. doi:10.1023/B:JMSC.0000039199.56155.f9.
   Web of Science ®Google Scholar
• Varma, R. S. 2012. Greener approach to nanomaterials and their sustainable applications. Current Opinion in Chemical Engineering 1 (2):123–8. doi:10.1016/j.coche.2011.12.002.
   Web of Science ®Google Scholar
• Venkatpurwar, V. P., and V. B. Pokharkar. 2010. Biosynthesis of gold nanoparticles using therapeutic enzyme in vitro and in-vivo efficacy study. Journal of Biomedical Nanotechnology 6 (6):667–74. doi:10.1166/jbn.2010.1163.
   PubMed Web of Science ®Google Scholar
• Vericat, C., M. E. Vela, G. Benitez, P. Carro, and R. C. Salvarezza. 2010. Self-assembled monolayers of thiols and dithiols on gold: New challenges for a well-known system. Chemical Society Reviews 39 (5):1805–34. doi:10.1039/b907301a.
   PubMed Web of Science ®Google Scholar
• Virkutyte, J., and R. S. Varma. 2011. Green synthesis of metal nanoparticles: Biodegradable polymers and enzymes in stabilization and surface functionalization. Chemical Science 2 (5):837–46. doi:10.1039/C0SC00338G.
   Web of Science ®Google Scholar
• Vladisavljević, G. T., N. Khalid, M. A. Neves, T. Kuroiwa, M. Nakajima, K. Uemura, S. Ichikawa, and I. Kobayashi. 2013. Industrial lab-on-a-chip: Design, applications and scale-up for drug discovery and delivery. Advanced Drug Delivery Reviews 65 (11–12):1626–63. doi:10.1016/j.addr.2013.07.017.
   PubMed Web of Science ®Google Scholar
• Wagner, V., A. Dullaart, A.-K. Bock, and A. Zweck. 2006. The emerging nanomedicine landscape. Nature Biotechnology 24 (10):1211–7. doi:10.1038/nbt1006-1211.
   PubMed Web of Science ®Google Scholar
• Whitesides, G. M. 2006. The origins and the future of microfluidics. Nature 442 (7101):368–73. doi:10.1038/nature05058.
   PubMed Web of Science ®Google Scholar
• Willets, K. A., and R. P. Van Duyne. 2007. Localized surface plasmon resonance spectroscopy and sensing. Annual Review of Physical Chemistry 58:267–97. doi:10.1146/annurev.physchem.58.032806.104607.
   PubMed Web of Science ®Google Scholar
• Wright, G. D. 1999. Aminoglycoside-modifying enzymes. Current Opinion in Microbiology 2 (5):499–503. doi:10.1016/S1369-5274(99)00007-7.
   PubMed Web of Science ®Google Scholar
• Yafout, M., A. Ousaid, Y. Khayati, and I. Otmani Sbai. 2021. Gold nanoparticles as a drug delivery system for standard chemotherapeutics: A new lead for targeted pharmacological cancer treatments. Scientific African 11: E00685. doi:10.1016/j.sciaf.2020.e00685.
   Google Scholar
• Yen, H. J., S. H. Hsu, and C. L. Tsai. 2009. Cytotoxicity and immuno-logical response of gold and silver nanoparticles of different sizes. Small (Weinheim an der Bergstrasse, Germany) 5 (13):1553–61. doi:10.1002/smll.200900126.
   PubMed Web of Science ®Google Scholar
• Zeng, S., X. Yu, W.-C. Law, Y. Zhang, R. Hu, X.-Q. Dinh, H.-P. Ho, and K.-T. Yong. 2013. Size dependence of Au NP-enhanced surface plasmon resonance based on differential phase measurement. Sensors and Actuators B: Chemical 176:1128–33. doi:10.1016/j.snb.2012.09.073.
   Web of Science ®Google Scholar
• Zhang, X.-F., Z.-G. Liu, W. Shen, and S. Gurunathan. 2016. Silver nanoparticles: Synthesis, characterization, properties, applications, and therapeutic approaches. International Journal of Molecular Sciences 17 (9):1534. doi:10.3390/ijms17091534.
   PubMed Web of Science ®Google Scholar
• Zhao, Y., Y. Tian, Y. Cui, W. Liu, W. Ma, and X. Jiang. 2010. Small molecule capped gold nanoparticles as potent antibacterial agents that target gram-negative bacteria. Journal of the American Chemical Society 132 (35):12349–56. doi:10.1021/ja1028843.
   PubMed Web of Science ®Google Scholar
• Zijlstra, P., J. W. M. Chon, and M. Gu. 2009. Five-dimensional optical recording mediated by surface plasmons in gold nanorods. Nature 459 (7245):410–3. doi:10.1038/nature08053.
   PubMed Web of Science ®Google Scholar