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REVIEW ARTICLE

The Relationship Between Psychogenic Cough and the Diagnosis and Misdiagnosis of Asthma: A Review

, D.O., M.P.H.
Pages 347-355 | Published online: 02 Jul 2009

References

  • Prakash U BS. Uncommon causes of cough: ACCP evidence-based clinical practice guidelines. Chest 2006; 129: 206S–219S
  • ERS Task Force. The diagnosis and management of chronic cough. Eur Respir J 2004; 24: 481–492
  • Mello C J, Irwin R S, Curley F J. Predictive values of the character, timing, and complications of chronic cough in diagnosing its cause. Arch Intern Med 1996; 156: 997–1003
  • Standards of Care Committee of the British Thoracic Society. BTS Guidelines for the Management of Chronic Obstructive Pulmonary Disease: forward. Thorax 1997; 52: S1–S28, http://thorax.bmj.com.ezproxy.meduohio.edu/cgi/reprint/52/suppl_5/S1 Accessed at
  • Thompson F, Masters I B, Chang A B. Persistent cough in children and the overuse of medications. J Paediatr Child Health 2002; 38: 578–581
  • French C L, Irwin R S, Curley F J, Krikorian C J. Impact of chronic cough on quality of life. Arch Intern Med 1998; 158: 1657–1661
  • French C T, Irwin R S, Fletcher K E, Adams T M. Evaluation of a cough-specific quality-of-life questionnaire. Chest 2002; 121: 1123–1131
  • Morice A H. Epidemiology of cough. Pulm Pharmacol Ther 2002; 15: 253–259
  • Marchant J M, Masters I B, Taylor S M, Cox N C, Seymour G J, Chang A B. Evaluation and outcome of young children with chronic cough. Chest 2006; 129: 1132–1141
  • Chang A B. Cough: are children really different to adults?. Cough 2005; 20: 1–7
  • Irwin R S, Curley F J, French C L. Chronic cough: the spectrum and frequency of causes, key components of the diagnostic evaluation, and outcome of specific therapy. Am Rev Respir Dis 1990; 141: 640–647
  • Mastrovich J D, Greenberger P A. Psychogenic cough in adults: A report of two cases and review of the literature. Allergy Asthma Proc 2002; 23: 27–33
  • Bordoy A, Sardon O, Mayoral J L, Mintegui J, Perez-Yarza E G. Psychogenic cough: Another etiology for persistent cough. An Pediatr (Barc) 2004; 61: 62–65
  • Irwin R S, Glomb W B, Chang A B. Habit cough, tic cough, and psychogenic cough in adult and pediatric populations. ACCP Evidence-Based Clinical Practice Guidelines. Chest 2006; 129: 174S–179S
  • Kravitz H, Gomberg R M, Burnstine R C, Hagler S, Korach A. Psychogenic cough tic in children and adolescents. Nine case histories illustrate the need for re-evaluation of this common but frequently unrecognized problem. Clin Pediatr (Phila) 1969; 8: 580–583
  • Bernstein L A. A respiratory tic: “The barking cough of puberty.”. Laryngoscope 1963; 73: 315–319
  • Weinberg E G. Honking, psychogenic cough tick in children. S Afr Med J 1980; 57: 198–200
  • Shuper A, Mukamel M, Mimouni M, Lerman M, Varsano I. Psychogenic cough. Arch Dis Child 1983; 58: 745–747
  • Berman B A. Habit cough in adolescent children. Ann Allergy 1966; 24: 43–46
  • Milner A D. Psychogenic cough in childhood. Br Med J 1985; 290: 1847–1848
  • Butani L, O'Connell E J. Functional respiratory disorders. Ann Allergy Asthma Immunol 1997; 79: 91–101
  • Irwin R S, Madison J M. The persistently troublesome cough. Am J Respir Crit CareMed 2002; 165: 1469–1474
  • Weinberg E G. Honking, psychogenic cough tick in children. S Afr Med J 1980; 57: 198–200
  • Irwin R S, Rosen M J, Braman S S. Cough: Comprehensive Review. Arch Intern Med 1977; 137: 1186–1191
  • Weinberg E G. Honking, psychogenic cough tick in children. S Afr Med J 1980; 57: 198–200
  • Haden J R, Khan D A. Psychiatric syndromes that mimic asthma. Adv Psychosom Med 2003; 24: 72–85
  • Health, United States, 2005. National Center for Health Statistics, Hyattsville, MD December 8, 2005; 63, http://www.cdc.gov/nchc/data/hus05.pdf Accessed October 30, 2006, at, (p 345.)
  • Dicpinigaitis P V. Chronic cough due to asthma. ACCP Evidence-Based Clinical Practice Guidelines. Chest 2006; 129: 75S–79S
  • ISAAC Steering Committee. Worldwide variations in the prevalence of asthma symptoms: The international study of asthma and allergies in childhood (ISAAC). Eur Respir J 1998; 12: 315–335
  • Ulrik C S, Postma D S, Backer V. Recognition of asthma in adolescents and young adults: Which objective measure is best?. J Asthma 2005; 42: 549–554
  • Mathur S K, Busse W W. Asthma: diagnosis and management. Med Clin North Am 2006; 90: 39–60
  • National Asthma Education and Prevention Program. Expert Panel Report 2. Clinical Practice Guidelines for the diagnosis and management of Asthma. US Department of Health and Human Services, Public Health Service, National Institutes of Health; National Heart, Lung, and Blood Institute, Rockville, MD 1997, NIH publ. 97-4051
  • Smith A D, Cowan J O, Filsell S, McLachlan C, Monti-Sheehan G, Jackson P, Taylor R. Diagnosing asthma: comparison between exhaled nitric oxide measurements and conventional tests. Am J Respir Crit Care Med 2004; 169: 473–478
  • Birnkrant D J, Picone C, Markowitz W, El Khwad M, Shen W H, Tafari N. Association of transient tachypnea of the newborn and childhood asthma. Pediatr Pulmonol 2006; 41: 978–984
  • McFadden E R. Exertional dyspnea and cough as preludes to acute asthmatic attacks of bronchial asthma. N Engl J Med 1975; 292: 555–559
  • Corrao W M, Braman S S, Irwin R S. Chronic cough as the sole presenting manifestation of bronchial asthma. N Engl J Med 1979; 300: 633–637
  • McGarvey L P, Heaney L G, Lawson J T, Johnston B T, Scally C M, Ennis M, Shepherd D R, MacMahon J. Evaluation and outcome of patients with chronic non-productive cough using a comprehensive diagnostic protocol. Thorax 1998; 53: 738–743
  • American Thoracic Society. Guidelines for methacholine and exercise challenge testing-1999. Am J Respir Crit Care Med 2000; 161: 309–329
  • Thiadens H A, De Bock G H, Van Houwelingen J C, Dekker F W, De Waal M W, Springer M P, Postma D S. Can peak expiratory flow measurements reliably identify the presence of airway obstruction and bronchodilator response as assessed by FEV (1) in primary care patients presenting with a persistent cough?. Thorax 1999; 54: 1055–1060
  • Nakajima T, Nishimara Y, Nishiuma T, Kotani Y, Funada Y, Nakata H, Yokoyama M. Characteristics of patients with chronic cough who developed classic asthma during the course of cough variant asthma: a longitudinal study. Respiration 2005; 72: 606–611, Epub 2005 Aug 11
  • de Benedictis F M, Selvaggio D, de Benedictis D. Cough, wheezing and asthma in children: lesson from the past. Pediatr Allergy Immunol 2004; 15: 386–393
  • Wright A L, Holberg C J, Morgan W J, Taussig L M, Halonen M, Martinez F D. Recurrent cough in childhood and its relation to asthma. Am J Respir Crit Care Med 1996; 153: 1259–1265
  • Chang A B, Phelan P D, Sawyer S M, Roberson C F. Airway hyperresponsiveness and cough-receptor sensitivity in children with recurrent cough. Am J Respir Crit Care Med 1997; 155: 1935–1939
  • Bellia V, Battaglia S, Catalano F, Scichilone N, Incalzi R A, Imperiale C, Rengo F. Aging and disability affect misdiagnosis of COPD in elderly asthmatics: The SARA study. Chest 2003; 123: 1066–1072
  • Frith P A. Asthma in the elderly. Curr Ther (Seaforth) 1999; 40: 19–31
  • Kitch B T, Levy B D, Fanta C H. Late onset asthma: epidemiology, diagnosis and treatment. Drugs Aging 2000; 17: 385–397
  • Burrows B, Barbee R A, Cline M G, Knudson R J, Lebowitz M D. Characteristics of asthma among elderly adults in a sample of the general population. Chest 1991; 100: 935–942
  • Wilson D, Appleton S L, Adams R J, Ruffin R E. Undiagnosed asthma in older people: an underestimated problem. Med J Aust, 2005; 183: S20–S22, (1 Suppl)
  • Strunk R C. Defining asthma in the preschool-aged child. Pediatrics 2002; 109: 357–361
  • Butani L, O'Connell E J. Functional respiratory disorders. Ann Allergy Asthma Immunol 1997; 79: 91–101
  • Okelo S O, Wu A W, Krishnan J A, Rand C S, Skinner E A, Diette G B. Emotional quality-of-life [QOL] and outcomes in adolescents with asthma. J Pediatr 2004; 145: 523–529
  • Wamboldt M Z, Wamboldt F S. Psychiatric aspects of respiratory syndromes. Pediatric Respiratory Medicine, L M Taussig, L I Landau. Mosby, St. Louis, MO 1999; 1222–1234
  • Fitzgerald D A, Kozlowska K. Habit cough: assessment and management. PaediatrRespir Rev 2006; 7: 21–25
  • Irwin R, Boulet L-P, Cloutier M M, Fuller R, Gold P M, Hoffstein V, Ing A J, McCool F D, O'Byrne P, Poe R H, Prakash U B, Pratter M R, Rubin B K. Managing cough as a defense mechanism and as a symptom. A Consensus Panel Report of the American College of Chest Physicians. Chest 1998; 114: 133S–181S
  • Anbar R D, Hall H R. Childhood habit cough treated with self-hypnosis. J Pediatr 2004; 144: 213–217
  • Goetz C, Tanner C M, Stebbins G T, Leipzig G, Carr W C. Adult tics in Gilles de la Tourette's syndrome: Description and risk factors. Neurology 1992; 42: 784–788
  • Niggemann B. Functional symptoms confused with allergic disorders in children and adolescents. Pediatr Allergy Immunol 2002; 13: 312–328
  • Brashear R E. Hyperventilation syndrome. Lung 1983; 161: 257–273
  • Kerr W J, Dalton J W, Gliebe P A. Some physical phenomena associated with anxiety states and their relation to hyperventilation. Ann Intern Med 1937; 11: 961–992
  • Cowley D S, Roy-Byrne P P. Hyperventilation and panic disorder. Am J Med 1987; 83: 929–937
  • Smoller J W, Pollack M H, Otto M W, Rosenbaum J F, Kradin R L. Panic anxiety, dyspnea, and respiratory disease. Theoretical and clinical considerations. Am J Respir Crit Care Med 1996; 154: 6–17
  • Malmberg L P, Tamminen K, Sovijärvi A RA. Orthostatic increase of respiratory gas exchange in hyperventilation syndrome. Thorax 2000; 55: 295–301
  • Vertigan A E, Theodoros D G, Gibson P G, Winkworth A L. The relationship between chronic cough and paradoxical vocal cord movement: A review of the literature. J Voice 2006; 20: 466–480
  • Wood R P, Milgrom H. Vocal cord dysfunction. J Allergy Clin Immunol 1996; 98: 481–485
  • Balkissoon R C, Blager F B. Vocal Cord dysfunction: often misdiagnosed and treated inappropriately. Med Sci Update 2002; 19: 1–7
  • Martin R J, Blager F B, Gay M L, Wood R P. Paradoxical vocal cord motion in presumed asthmatics. Semin Respir Med 1987; 8: 332–337
  • Andrianopolous M V, Gallivan G J, Gallivan K H. PVCM, PVCD, EPL, and irritable larynx syndrome: what are we talking about and how do we treat it?. J Voice 2000; 14: 607–618
  • Newman K B, Mason U G, 3rd, Schmalling K B. Clinical features of vocal cord dysfunction. Am J Respir Crit Care Med 1995; 152: 1382–1386
  • Perkins P J, Morris M J. Vocal cord dysfunction induced by methacholine challenge testing. Chest 2002; 122: 1988–1933
  • Yano T, Hashimoto M, Kouchi A. Two cases of flaccid epiglottis. Masuri 2005; 54: 500–503
  • Kastelik J A, Aziz I, Ojoo J C, Thompson R H, Redington A E, Morice A H. Investigation and management of chronic cough using a probability-based algorithm. Eur Respir J 2005; 25: 235–243
  • Johnston B T, McFarland R J, Collins J S, Love A H. Symptom index as a marker of gastro-oesophageal reflux disease. Br J Surg 1992; 79: 1054–1055
  • Cloutier M M, Loughlin G M. Chronic cough in children: a manifestation of airway hyper-reactivity. Pediatrics 1981; 67: 6–11
  • Tsao C H, Chen L C, Yeh K W, Huang J L. Concomitant chronic sinusitis treatment in children with mild asthma: the effect on bronchial hyperresponsiveness. Chest 2003; 123: 757–764
  • Lai L, Hopp R J, Lusk R P. Pediatric chronic sinusitis and asthma: a review. J Asthma 2006; 43: 719–725
  • Rachelefsky G S, Katz R M, Siegel S C. Chronic sinus disease with associated reactive airway disease in children. Pediatrics 1984; 73: 526–529
  • Corren J, Adinoff A D, Buchmeier A D, Irvin C G. Nasal beclomethasone prevents the seasonal increase in bronchial responsiveness in patients with allergic rhinitis and asthma. J Allergy Clin Immunol 1992; 90: 250–256
  • Tilles S A. Differential diagnosis of adult asthma. Med Clin North Am 2006; 90: 61–76
  • Tinkelman D G, Price D B, Nordyke R J, Halbert R J. Misdiagnosis of COPD and asthma in primary care patients 40 years of age and over. J Asthma 2006; 43: 75–80
  • Chhabra S K. Acute bronchodilator response has limited value in differentiating bronchial asthma from COPD. J Asthma 2005; 42: 367–372
  • Empey D W, Laitinen L A, Jacobs L, Gold W M, Nadel J A. Mechanisms of bronchial hyperactivity in normal subjects after upper respiratory infections. Am Rev Respir Dis 1976; 113: 131–139
  • Laitinen L A, Elkin R B, Empey D W, Jacobs L, Mills J, Nadel J A. Bronchial hyperresponsiveness in normal subjects during attenuated influenza virus infection. Am Rev Respir Dis 1991; 143: 358–361
  • Hallander H O, Gnarpe J, Gnarpe H, Olin P. Bordetella pertussis, Bordetella parapertussis, Mycoplasma pneumoniae, Chlamydia pneumoniae and persistent cough in children. Scand J Infect Dis 1999; 31: 281–286
  • Lee Y H, Sin Fai Lam K N. Endobronchial tuberculosis simulating bronchial asthma. Singapore Med J 2004; 45: 390–392
  • Braman S S. Post infectious cough. ACCP Evidence-Based Clinical Practice Guidelines. Chest 2006; 129: 138S–146S
  • Allen J N, Davis W B. State of the art: the eosinophilic lung diseases. Am J Respir Crit Care Med 1994; 150: 1423–1438
  • Potter M B, Fincher R K, Finger D R. Eosinophilia in Wegener's granulomatosis. Chest 1999; 116: 1480–1483
  • Katzenstein A. Diagnostic features and differential diagnosis of Churg-Strauss syndrome in the lung. A review. Am J Clin Pathol 2000; 114: 767–772
  • Nayak U G, Jaffrey H, Stone C. Non-allergic granulomatosis with eosinophilia: a new entity in eosinophilic lung disease. Chest 2003; 124: 245S–246S
  • Gibson P G, Hargreave F E, Girgis-Gabardo A, Morris M, Denburg J A, Dolovich J. Chronic cough with eosinophilic bronchitis: examination for variable airflow obstruction and response to corticosteroid. Clin Exp Allergy 1995; 25: 127–132
  • Wolff A P, May M, Nuelle D. The tympanic membrane. A source of the cough reflex. JAMA 1973; 223: 1269
  • Tekdemir I, Aslan A, Elhan A. A clinico-anatomic study of the auricular branch of the vagus nerve and Arnold's ear-cough reflex. Surg Radiol Anat 1998; 20: 253–257
  • Morice A H, Lowry R, Brown M J, Higenbottam T. Angiotensin-converting enzyme and the cough reflex. Lancet 1987; 2: 1116–1118
  • Howaizi M, Delafosse C. Omeprazole-induced intractable cough. Ann Pharmacother 2003; 37: 1607–1609
  • Legasto A C, Haller J O, Giusti R J. Tracheal web. Pediatr Radiol 2004; 34: 256–258
  • Stoica S C, Lockowandt U, Coulden R, et al. Double aortic arch masquerading as asthma for thirty years. Respiration 2002; 69: 92–95
  • Ashiku S K. Idiopathic laryngotracheal stenosis. Chest Surg Clin North Am 2003; 13: 257–269
  • Vahid B, Zangrilli J. Upper airway disease presenting as refractory asthma. Int J Otorhinolaryngol 2006; 4(2), http://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijorl/vol4n2/asthma.xml ISSN: 1528-8420. Accessed at
  • Vijayasekararan D, Giridhar S, Gowrishankar N C, Nedunchelian K, Senguttuvan M. Pediatric Interstitial lung disease. Indian Pediatr 2006; 43: 817–820
  • Sahay S, Mathur R K, Shah A. Isolated left lung aplasia with bronchial asthma. Indian Pediatr 2006; 43: 817–820, http://www.indianp-ediatrics.net/sep2006/817.pdf
  • Irwin R S, Corrao W M, Pratter M R. Chronic persistent cough in the adult: The spectrum and frequency of causes and successful outcome of specific therapy. Am Rev Respir Dis 1981; 123: 413–417
  • Moser K M. Pulmonary embolism. Am Rev Respir Dis 1977; 115: 829–852
  • Hultgren H N, Honigman B, Theis K, Nicholas D. High-altitude pulmonary edema at a ski resort. W J Med 1996; 164: 222–227
  • Sorhage F, Stover D E, Mortazavi A. Unusual etiology of cough in a woman with asthma. Chest 1996; 110: 852–854
  • Chu S C, Horiba K, Usuki J, Avila N A, Chen C C, Travis W D, Ferrans V J, Moss J. Comprehensive evaluation of 35 patients with lymphangioleiomatosis. Chest 1999; 115: 1041–1052
  • Tazi A, Soler P, Hance A J. Adult pulmonary Langerhans cell histiocytosis. Thorax 2000; 55: 405–416
  • Sharma S K, Ahluwalia G, Ahluwalia A, Mukhopadhyay S. Tracheobronchial amyloidosis masquerading as bronchial asthma. Indian J Chest Dis Allied Sci 2004; 46: 117–119
  • Brightling C E. Chronic cough doe to nonasthmatic eosinophilic bronchitis: ACCP Evidence-based Clinical Practice Guidelines. Chest 2006; 129: 166S–121S, (1suppl)
  • Powell C, Brazier A. Psychological approaches to the management of respiratory symptoms in children and adolescents. Paediatr Respir Rev 2004; 5: 214–224
  • Cohlan S Q, Stone S M. The cough and the bedsheet. Pediatrics 1984; 74: 11–15
  • Lorin M I, Slovis T L, Haller J O. Fracture of ribs in psychogenic cough. N Y State J Med 1978; 78: 2078–2079
  • Anbar R D, Geisler S C. Identification of children who may benefit from self-hypnosis at a pediatric pulmonary center. BMC Pediatrics 2005; 5(1)6, http://www.pubmedcentral.nih.gov/picrender.fegi?artid-11126008blobtype-pdf Accessed May 21, 2007, at
  • Bennett D S. Depression among children with chronic medical problems: a meta–analysis. J Pediatr Psychol 1994; 19: 149–169
  • Mrazek D A. Psychiatric complications of pediatric asthma. Ann Allergy 1992; 69: 285–290
  • Bastian R W, Vaida A M, Delsupehe K G. Sensory neuropathic cough: a common and treatable cause of chronic cough. Otolaryngol Head Neck Surg 2006; 135: 17–21
  • Linz A J, Daniels R W, Fallon L F, Jr. Psychogenic cough in an asthmatic child: case report with unusual findings. J Asthma 2007; 44: 13–18
  • Kugelman A, Shaoul R, Goldsher M, Srugo I. Persistent cough and failure to thrive: a presentation of foreign body aspiration in a child with asthma. Pediatrics 2006; 117: e1057–1060
  • Tarlo S M. Cough: occupational and environmental considerations. ACCP Evidence-Based Clinical Practice Guidelines. Chest 2006; 129: 186S–196S
  • Brand P L, Dulverman E J. Coughing and wheezing children: improvement after parents stop smoking. Ned Tijdschr Geneeskd 1998; 142: 825–827

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