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ORIGINAL ARTICLE

The FEF25–75 and its Decline as a Predictor of Methacholine Responsiveness in Children

, M.D., , R.P.F.T., , R.P.F.T., R.R.T., , PH.D, , M.A. & , M.D.
Pages 375-381 | Published online: 21 Jul 2009

References

  • Sheffer A L. National Asthma Education Project: Guidelines for the diagnosis and management of asthma. 1991, US Department of Health and Human Services. Pub. 91–3042
  • Birnbaum S, Barreiro T J. Methacholine challenge testing: identifying its diagnostic role, testing, coding, and reimbursement. Chest 2007; 131: 1932–1935
  • Liem J J, Kozyrskyj A L, Cockroft D W, Becker A B. Diagnosing asthma in children: what is the role for methacholine bronchoprovocation testing?. Pediatr Pulmonol 2008; 43: 481–489
  • Yurdakul A S, Dursun B, Canbakan S, Cakaloğlu A, Capan N. The assessment of validity of different asthma diagnostic tools in adults. J Asthma 2005; 42: 843–846
  • American Thoracic Society. Guidelines for methacholine and exercise challenge testing-1999. Am J Respir Crit Care Med 2000; 161: 309–329
  • Godfrey S, Springer C, Bar-Yishay E, Avital A. Cut-off points defining normal and asthmatic bronchial reactivity to exercise and inhalation challenges in children and young adults. Eur Respir J 1999; 14: 659–668
  • Ownby D R, Peterson E L, Johnson C C. Factors related to methacholine airway responsiveness. Am J Respir Crit Care Med 2000; 161: 1578–1583
  • Harber P. Assessing occupational disability from asthma. J Occup Med 1992; 33: 120–128
  • Lebecque P, Kiakulanda P, Coates A L. Is FEF25 −75 a more sensitive test than FEV1/FVC?. Pediatr Pulmonol 1993; 16: 19–22
  • Alberts M, Ferris M C, Brooks S M, Goldman A L. The FEF25 −75% and the clinical diagnosis of asthma. Ann Allergy 1994; 74: 221–225
  • Goldstein M F, Pacana S M, Dvorin D J, Dunsky E H. Retrospective analyses of methacholine inhalation challenges. Chest 1994; 105: 1082–1088
  • Easton J G. Patterns of response to inhaled methacholine. Ann Allergy 1983; 50: 171–173
  • Cirillo I, Klersy C, Marseglia G L, et al. Role of FEF25% − 75% as a predictor of bronchial hyperreactivity in allergic patients. Ann Allergy Asthma Immunol 2006; 96: 692–700
  • Polgar G, Promadhat V. Pulmonary function testing in children: techniques and standards. WB Saunders Company, Philadelphia 1971
  • Chai H, Farr R S, Froehlich L A, et al. Standardization of bronchial inhalation challenge procedures. J Allergy Clin Immunol 1975; 56: 323–327
  • Peat J K, Salome M, Xuan W. On adjusting measurements of airway responsiveness for lung size and airway caliber. Am J Respir Crit Care Med 1996; 154: 870–875
  • Hopp R, Bewtra A K, Nair M, Watt G D, Townley R G. Methacholine inhalation challenge studies in a selected pediatric population. Am Rev Respir Dis 1986; 134: 994–998
  • Becklake M, Carpo R O. Lung function testing: selection of reference values and interpretative strategies. Am Rev Respir Dis 1991; 144: 1202–1218
  • Green M, Mead J, Turner J M. Variability of maximum expiratory flow volume curves. J Appl Physiol 1974; 37: 67–74
  • Tager I B, Weiss S T, Munoz A, et al. Determinants of response to eucapneic hyperventilation with cold air in a population based study. Am Rev Respir Dis 1986; 134: 502–508
  • Litonjua A A, Sparrow D, Weiss S T. The FEF25 −75/FVC ratio is associated with methacholine airway responsiveness. The normative aging study. Am J Respir Crit Care Med 1999; 159: 1574–1579
  • Parker A L, Abu-Hijleh M, McCool F D. Ratio between forced expiratory flow between 25% and 75% of vital capacity and FVC is a determinant of airway reactivity and sensitivity to methacholine. Chest 2003; 124: 63–69
  • Soferman R, Spirer Z, Topilsky M. Small airway responsiveness to exercise as an objective measure of exercise induced asthma in children. Pediatr Asthma Allergy Immunol 2003; 16: 77–84
  • Fonseca-Guedes C HF, Cabral A LB, Martins M A. Exercise induced bronchospasm in children: comparison of FEV1 and FEF25 −75% responses. Pediatr Pulmonol 2003; 36: 49–54

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