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Pediatric Asthma

Quantitation of salbutamol using micro-volume blood sampling – applications to exacerbations of pediatric asthma

, Ph.D., , M.Sc, , MD, , MD, , Ph.D. & , D.Phil ORCID Icon
Pages 1205-1213 | Received 07 Sep 2017, Accepted 03 Nov 2017, Published online: 06 Dec 2017

References

  • Asthma UK. Key facts and statistics. http://www.asthma.org.uk/asthma-facts-and-statistics.
  • British Guideline on the Management of Asthma. A national clinical guideline. (Guideline 101). British Thoracic Society and Scottish Intercollegiate Guidelines Network, 2012.
  • Morris I, Lyttle MD, O'Sullivan R, Sargant N, Doull IJM, Powell CVE. Which intravenous bronchodilators are being administered to children presenting with acute severe wheeze in the UK and Ireland?. Thorax. 2015;70:88–91.
  • Tobin A. Intravenous salbutamol: too much of a good thing?. Critical care and resuscitation: journal of the Australasian Academy of Critical Care Medicine. 2005;7:119–127.
  • Starkey ES, Mulla H, Sammons HM, Pandya HC. Intravenous salbutamol for childhood asthma: evidence-based medicine? Arch Dis Child. 2014;99:873–877.
  • GlaxoSmithKline. PrVENTOLIN® I.V. infusion solution. 2014, http://ca.gsk.com/media/536498/ventolin-iv.pdf.
  • Cella M, Knibbe C, Danhof M, Della Pasqua O. What is the right dose for children?. British journal of clinical pharmacology. 2010;70:597–603.
  • Hawcutt DB, Cooney L, Oni L, Pirmohamed M. Precision Dosing in Children. Expert Review of Precision Medicine and Drug Development. 2016;1(1):69–78.
  • Guthrie R, Susi A. A simple phenylalanine method for detecting pheylketonuria in large populations of newborn infants. Pediatrics. 1963;32:338–343.
  • Stove CP, Ingels AS, De Kesel PM, Lambert WE. Dried blood spots in toxicology: from the cradle to the grave?. Critical reviews in toxicology. 2012;42:230–243.
  • Wilcken B, Wiley V, Hammond J, Carpenter K. Screening newborns for inborn errors of metabolism by tandem mass spectrometry. N Engl J Med. 2003;348:2304–2312.
  • Demirev PA. Dried Blood Spots: Analysis and Applications. Analytical Chemistry. 2012;85:779–789.
  • Edelbroek PM, van der Heijden J, Stolk LM. Dried blood spot methods in therapeutic drug monitoring: methods, assays, and pitfalls. Therapeutic drug monitoring. 2009;31:327–336.
  • Denniff P, Spooner N. The effect of hematocrit on assay bias when using DBS samples for the quantitative bioanalysis of drugs. Bioanalysis. 2010;2:1385–1395.
  • de Vries R, Barfield M, van de Merbel N, et al. The effect of hematocrit on bioanalysis of DBS: results from the EBF DBS-microsampling consortium. Bioanalysis. 2013;5:2147–2160.
  • De Kesel PMM, Sadones N, Capiau S, Lambert WE, Stove CP. Hemato-critical issues in quantitative analysis of dried blood spots: challenges and solutions. Bioanalysis. 2013;5:2023–2041.
  • Youhnovski N, Bergeron A, Furtado M, Garofolo F. Pre-cut dried blood spot (PCDBS): an alternative to dried blood spot (DBS) technique to overcome hematocrit impact. Rapid Commun Mass Spectrom. 2011;25:2951–2958.
  • Li F, Zulkoski J, Fast D, Michael S. Perforated dried blood spots: a novel format for accurate microsampling. Bioanalysis. 2011;3:2321–2333.
  • Fan L, Lee JA. Managing the effect of hematocrit on DBS analysis in a regulated environment. Bioanalysis. 2012;4:345–347.
  • Denniff P, Spooner N. Volumetric Absorptive Microsampling: A Dried Sample Collection Technique for Quantitative Bioanalysis. Analytical Chemistry. 2014;86:8489–8495.
  • Spooner N, Denniff P, Michielsen L, et al. A device for dried blood microsampling in quantitative bioanalysis: overcoming the issues associated blood hematocrit. Bioanalysis. 2014;7:653–659.
  • De Kesel PMM, Lambert WE, Stove CP. Does volumetric absorptive microsampling eliminate the hematocrit bias for caffeine and paraxanthine in dried blood samples? A comparative study. Analytica Chimica Acta. 2015;881:65–73.
  • Li W, Tse FL. Dried blood spot sampling in combination with LC-MS/MS for quantitative analysis of small molecules. Biomedical chromatography: BMC. 2010;24:49–65.
  • Elers J, Pedersen L, Henninge J, et al. Blood and urinary concentrations of salbutamol in asthmatic subjects. Medicine and science in sports and exercise. 2010;42:244–249.
  • De Brabanter N, Van Gansbeke W, Geldof L, Van Eenoo P. An improved gas chromatography screening method for doping substances using triple quadrupole mass spectrometry, with an emphasis on quality assurance. Biomedical chromatography: BMC. 2012;26:1416–1435.
  • Caban M, Stepnowski P, Kwiatkowski M, Migowska N, Kumirska J. Determination of beta-blockers and beta-agonists using gas chromatography and gas chromatography-mass spectrometry–a comparative study of the derivatization step. Journal of chromatography. A. 2011;1218:8110–8122.
  • Anderson PJ, Zhou X, Breen P, et al. Pharmacokinetics of (R,S)-Albuterol after aerosol inhalation in healthy adult volunteers. Journal of Pharmaceutical Sciences. 1998;87:841–844.
  • Bergés R, Segura J, Ventura R, et al. Discrimination of prohibited oral use of salbutamol from authorized inhaled asthma treatment. Clin Chem. 2000;46:1365–1375.
  • Forsdahl G, Gmeiner G. Quantification and stability of salbutamol in human urine. Journal of Separation Science. 2004;27:110–114.
  • Ventura R, Segura J, Berges R, et al. Distinction of inhaled and oral salbutamol by urine analysis using conventional screening procedures for doping control. Therapeutic drug monitoring. 2000;22:277–282.
  • Lei Y-C, Tsai Y-F, Tai Y-T, et al. Development and Fast Screening of Salbutamol Residues in Swine Serum by an Enzyme-Linked Immunosorbent Assay in Taiwan. Journal of Agricultural and Food Chemistry. 2008;56:5494–5499.
  • Thomas A, Geyer H, Schänzer W, et al. Sensitive determination of prohibited drugs in dried blood spots (DBS) for doping controls by means of a benchtop quadrupole/Orbitrap mass spectrometer. Anal Bioanal Chem. 2012;403:1279–1289.
  • Damasceno L, Ventura R, Ortuno J, Segura J. Derivatization procedures for the detection of beta(2)-agonists by gas chromatographic/mass spectrometric analysis. Journal of mass spectrometry: JMS. 2000;35:1285–1294.
  • Versace F, Déglon J, Lauer E, Mangin P, Staub C. Automated DBS Extraction Prior to Hilic/RP LC–MS/MS Target Screening of Drugs. Chromatographia. 2013;76:1281–1293.
  • Thevis M, Thomas A, Schänzer W. Targeting prohibited substances in doping control blood samples by means of chromatographic–mass spectrometric methods. Anal Bioanal Chem. 2013;405:9655–9667.
  • Koster RA, Botma R, Greijdanus B, et al. The influence of the dried blood spot drying time on the recoveries of six immunosuppressants. Journal of Applied Bioanalysis. 2015;1:116–122.
  • Food and Drug Administration. Guidance for Industry Process Validation: General Principles and Practices. 2011.
  • Jantos R, Skopp G. Comparison of drug analysis in whole blood and dried blood spots. Toxichem Krimtech. 2011;78:268–275.
  • Rhee J, Erickson T, Barceloux DG. Clenbuterol and Salbutamol (Albuterol). Medical Toxicology of Drug Abuse. 2012. John Wiley & Sons, Inc., 295–305.
  • Morgan DJ. Pharmacokinetics of intravenous and oral salbutamol and its sulphate conjugate. British journal of clinical pharmacology. 1986;22.5:587–593.

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