Association between probiotic supplementation and asthma incidence in infants: a meta-analysis of randomized controlled trials

References

• Tesse R, Borrelli G, Mongelli G, Mastrorilli V, Cardinale F. Treating pediatric asthma according guidelines. Front Pediatr 2018;6:234.
   PubMed Web of Science ®Google Scholar
• Akinbami LJ, Simon AE, Schoendorf KC. Trends in allergy prevalence among children aged 0-17 years by asthma status, United States, 2001-2013. J Asthma 2016;53:356–362. doi:10.3109/02770903.2015.1126848
   PubMed Web of Science ®Google Scholar
• Bryant-Stephens T. Asthma disparities in urban environments. J Allergy Clin Immunol 2009;123:1199–1206.
   PubMed Web of Science ®Google Scholar
• Johnson CC, Ownby DR. The infant gut bacterial microbiota and risk of pediatric asthma and allergic diseases. Transl Res 2017;179:60–70.
   PubMed Web of Science ®Google Scholar
• Moonie SA, Sterling DA, Figgs L, Castro M. Asthma status and severity affects missed school days. J Sch Health 2006;76:18–24.
   PubMed Web of Science ®Google Scholar
• Clarke SA, Calam R. The effectiveness of psychosocial interventions designed to improve health related quality of life (HRQOL) amongst asthmatic children and their families: a systematic review. Qual Life Res 2012;21:747–764. doi:10.1007/s11136-011-9996-2
   PubMed Web of Science ®Google Scholar
• Rautava S, Ruuskanen O, Ouwehand A, Salminen S, Isolauri E. The hygiene hypothesis of atopic disease-an extended version. J Pediatr Gastroenterol Nutr 2004;38:378–388. doi:10.1097/00005176-200404000-00004
   PubMed Web of Science ®Google Scholar
• Wold AE. The hygiene hypothesis revised: is the rising frequency of allergy due to changes in the intestinal flora? Allergy 1998;53:20–25.
   PubMed Web of Science ®Google Scholar
• Pelucchi C, Chatenoud L, Turati F, Galeone C, Moja L, Bach J-F, La Vecchia C, et al. Probiotics supplementation during pregnancy or infancy for the prevention of atopic dermatitis: a meta-analysis. Epidemiology 2012;23:402–414.
   PubMed Web of Science ®Google Scholar
• Hill C, Guarner F, Reid G, Gibson GR, Merenstein DJ, Pot B, Morelli L, et al. Expert consensus document. The International Scientific Association for Probiotics and Prebiotics consensus statement on the scope and appropriate use of the term probiotic. Nat Rev Gastroenterol Hepatol 2014;11:506–514.
   PubMed Web of Science ®Google Scholar
• Noverr MC, Huffnagle GB. The 'microflora hypothesis' of allergic diseases. Clin Exp Allergy 2005;35:1511–1520.
   PubMed Web of Science ®Google Scholar
• Higgins JPT, Green S. Cochrane handbook for systematic reviews of interventions, version 5.1.0 (updated March 2011). Cochrane Collaboration website. Available from: http://training.cochrane.org/handbook. 2011.
   Google Scholar
• Liberati A, Altman DG, Tetzlaff J, Mulrow C, Gotzsche PC, Ioannidis JPA, Clarke M, et al. The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate healthcare interventions: explanation and elaboration. BMJ 2009;339:b2700. doi:10.1136/bmj.b2700
   PubMed Web of Science ®Google Scholar
• Herzog R, Cunningham-Rundles S. Pediatric asthma: natural history, assessment, and treatment. Mt Sinai J Med 2011;78:645–660.
   PubMedGoogle Scholar
• Abrahamsson TR, Jakobsson T, Böttcher MF, Fredrikson M, Jenmalm MC, Björkstén B, Oldaeus G, et al. Probiotics in prevention of IgE-associated eczema: a double-blind, randomized, placebo-controlled trial. J Allergy Clin Immunol 2007;119:1174–1180. doi:10.1016/j.jaci.2007.01.007
   PubMed Web of Science ®Google Scholar
• Berni Canani R, Di Costanzo M, Bedogni G, Amoroso A, Cosenza L, Di Scala C, Granata V, et al. Extensively hydrolyzed casein formula containing Lactobacillus rhamnosus GG reduces the occurrence of other allergic manifestations in children with cow's milk allergy: 3-year randomized controlled trial. J Allergy Clin Immunol 2017;139:1906–1913.
   PubMed Web of Science ®Google Scholar
• Boyle RJ, Ismail IH, Kivivuori S, Licciardi PV, Robins-Browne RM, Mah L-J, Axelrad C, et al. Lactobacillus GG treatment during pregnancy for the prevention of eczema: a randomized controlled trial. Allergy 2011;66:509–516.
   PubMed Web of Science ®Google Scholar
• Cabana MD, McKean M, Caughey AB, Fong L, Lynch S, Wong A, et al. Early probiotic supplementation for eczema and asthma prevention: a randomized controlled trial. Pediatrics 2017;140:1–9.
   Web of Science ®Google Scholar
• Dotterud CK, Storrø O, Johnsen R, Oien T. Probiotics in pregnant women to prevent allergic disease: a randomized, double-blind trial. Br J Dermatol 2010;163:616–623. doi:10.1111/j.1365-2133.2010.09889.x
   PubMed Web of Science ®Google Scholar
• Gore C, Custovic A, Tannock GW, Munro K, Kerry G, Johnson K, Peterson C, et al. Treatment and secondary prevention effects of the probiotics Lactobacillus paracasei or Bifidobacterium lactis on early infant eczema: randomized controlled trial with follow-up until age 3 years. Clin Exp Allergy 2012;42:112–122.
   PubMed Web of Science ®Google Scholar
• Niers L, Martín R, Rijkers G, Sengers F, Timmerman H, van Uden N, Smidt H, et al. The effects of selected probiotic strains on the development of eczema (the PandA study). Allergy 2009;64:1349–1358.
   PubMed Web of Science ®Google Scholar
• Hol J, van Leer EHG, Elink Schuurman BEE, de Ruiter LF, Samsom JN, Hop W, Neijens HJ, et al. The acquisition of tolerance toward cow’s milk through probiotic supplementation: a randomized, controlled trial. J Allergy Clin Immunol 2008;121:1448–1454. doi:10.1016/j.jaci.2008.03.018
   PubMed Web of Science ®Google Scholar
• Kalliomäki M, Salminen S, Arvilommi H, Kero P, Koskinen P, Isolauri E. Probiotics in primary prevention of atopic disease: a randomised placebo-controlled trial. Lancet 2001;357:1076–1079. doi:10.1016/S0140-6736(00)04259-8
   PubMed Web of Science ®Google Scholar
• Kauppi PK, Kuokkanen MK, Kukkonen KK, Laitinen TH, Kuitunen MK. Interaction of NPSR1 genotypes and probiotics in the manifestation of atopic eczema in early childhood. Allergol Immunopathol (Madr) 2014;42:560–567.
   PubMed Web of Science ®Google Scholar
• Kopp MV, Hennemuth I, Heinzmann A, Urbanek R. Randomized, double-blind, placebo-controlled trial of probiotics for primary prevention: no clinical effects of Lactobacillus GG supplementation. Pediatrics 2008;121:e850–e856.
   PubMed Web of Science ®Google Scholar
• Kukkonen K, Savilahti E, Haahtela T, Juntunen-Backman K, Korpela R, Poussa T, Tuure T, Kuitunen M. Probiotics and prebiotic galacto-oligosaccharides in the prevention of allergic diseases: a randomized, double-blind, placebo-controlled trial. J Allergy Clin Immunol 2007;119:192–198. doi:10.1016/j.jaci.2006.09.009
   PubMed Web of Science ®Google Scholar
• Loo EX, Llanora GV, Lu Q, Aw MM, Lee BW, Shek LP. Supplementation with probiotics in the first 6 months of life did not protect against eczema and allergy in at-risk Asian infants: a 5-year follow-up. Int Arch Allergy Immunol 2014;163:25–28.
   PubMed Web of Science ®Google Scholar
• Ou C-Y, Kuo H-C, Wang L, Hsu T-Y, Chuang H, Liu C-A, Chang J-C, et al. Prenatal and postnatal probiotics reduces maternal but not childhood allergic diseases: a randomized, double-blind, placebo-controlled trial. Clin Exp Allergy 2012;42:1386–1396. doi:10.1111/j.1365-2222.2012.04037.x
   PubMed Web of Science ®Google Scholar
• Taylor AL, Dunstan JA, Prescott SL. Probiotic supplementation for the first 6 months of life fails to reduce the risk of atopic dermatitis and increases the risk of allergen sensitization in high-risk children: a randomized controlled trial. J Allergy Clin Immunol 2007;119:184–191. doi:10.1016/j.jaci.2006.08.036
   PubMed Web of Science ®Google Scholar
• van der Aa LB, van Aalderen WMC, Heymans HSA, Henk Sillevis Smitt J, Nauta AJ, Knippels LMJ, Ben Amor K, et al. Synbiotics prevent asthma-like symptoms in infants with atopic dermatitis. Allergy 2011;66:170–177.
   PubMed Web of Science ®Google Scholar
• West CE, Hammarström ML, Hernell O. Probiotics during weaning reduce the incidence of eczema. Pediatr Allergy Immunol 2009;20:430–437. doi:10.1111/j.1399-3038.2009.00745.x
   PubMed Web of Science ®Google Scholar
• Wickens K, Black PN, Stanley TV, Mitchell E, Fitzharris P, Tannock GW, Purdie G, et al. A differential effect of 2 probiotics in the prevention of eczema and atopy: a double-blind, randomized, placebo-controlled trial. J Allergy Clin Immunol 2008;122:788–794. doi:10.1016/j.jaci.2008.07.011
   PubMed Web of Science ®Google Scholar
• Wickens K, Barthow C, Mitchell EA, Stanley TV, Purdie G, Rowden J, Kang J, et al. Maternal supplementation alone with Lactobacillus rhamnosus HN001 during pregnancy and breastfeeding does not reduce infant eczema. Pediatr Allergy Immunol 2018;29:296–302.
   PubMed Web of Science ®Google Scholar
• Abrahamsson TR, Jakobsson T, Björkstén B, Oldaeus G, Jenmalm MC. No effect of probiotics on respiratory allergies: a seven-year follow-up of a randomized controlled trial in infancy. Pediatr Allergy Immunol 2013;24:556–561. doi:10.1111/pai.12104
   PubMed Web of Science ®Google Scholar
• Simpson MR, Dotterud CK, Storrø O, Johnsen R, Øien T. Perinatal probiotic supplementation in the prevention of allergy related disease: 6 year follow up of a randomised controlled trial. BMC Dermatol 2015;15:13.
   PubMed Web of Science ®Google Scholar
• Gorissen DMW, Rutten NBMM, Oostermeijer CMJ, Niers LEM, Hoekstra MO, Rijkers GT, van der Ent CK, et al. Preventive effects of selected probiotic strains on the development of asthma and allergic rhinitis in childhood. The Panda study. Clin Exp Allergy 2014;44:1431–1433. doi:10.1111/cea.12413
   PubMed Web of Science ®Google Scholar
• Kalliomäki M, Salminen S, Poussa T, Arvilommi H, Isolauri E. Probiotics and prevention of atopic disease: 4-year follow-up of a randomised placebo-controlled trial. Lancet 2003;361:1869–1871. doi:10.1016/S0140-6736(03)13490-3
   PubMed Web of Science ®Google Scholar
• Kalliomäki M, Salminen S, Poussa T, Isolauri E. Probiotics during the first 7 years of life: a cumulative risk reduction of eczema in a randomized, placebo-controlled trial. J Allergy Clin Immunol 2007;119:1019–1021. doi:10.1016/j.jaci.2006.12.608
   PubMed Web of Science ®Google Scholar
• Kuitunen M, Kukkonen K, Juntunen-Backman K, Korpela R, Poussa T, Tuure T, Haahtela T, et al. Probiotics prevent IgE-associated allergy until age 5 years in cesarean-delivered children but not in the total cohort. J Allergy Clin Immunol 2009;123:335–341.
   PubMed Web of Science ®Google Scholar
• Prescott SL, Wiltschut J, Taylor A, Westcott L, Jung W, Currie H, Dunstan JA, et al. Early markers of allergic disease in a primary prevention study using probiotics: 2.5-year follow-up phase. Allergy 2008;63:1481–1490. doi:10.1111/j.1398-9995.2008.01778.x
   PubMed Web of Science ®Google Scholar
• Jensen MP, Meldrum S, Taylor AL, Dunstan JA, Prescott SL. Early probiotic supplementation for allergy prevention: long-term outcomes. J Allergy Clin Immunol 2012;130:1209–1211. doi:10.1016/j.jaci.2012.07.018
   PubMed Web of Science ®Google Scholar
• West CE, Hammarström ML, Hernell O. Probiotics in primary prevention of allergic disease-follow-up at 8-9 years of age. Allergy 2013;68:1015–1020.
   PubMed Web of Science ®Google Scholar
• Wickens K, Black P, Stanley TV, Mitchell E, Barthow C, Fitzharris P, Purdie G, et al. A protective effect of Lactobacillus rhamnosus HN001 against eczema in the first 2 years of life persists to age 4 years. Clin Exp Allergy 2012;42:1071–1079. doi:10.1111/j.1365-2222.2012.03975.x
   PubMed Web of Science ®Google Scholar
• Wickens K, Stanley TV, Mitchell EA, Barthow C, Fitzharris P, Purdie G, Siebers R, et al. Early supplementation with Lactobacillus rhamnosus HN001 reduces eczema prevalence to 6 years: does it also reduce atopic sensitization? Clin Exp Allergy 2013;43:1048–1057.
   PubMed Web of Science ®Google Scholar
• Azad MB, Coneys JG, Kozyrskyj AL, Field CJ, Ramsey CD, Becker AB, Friesen C, et al. Probiotic supplementation during pregnancy or infancy for the prevention of asthma and wheeze: systematic review and meta-analysis. BMJ 2013;347:f6471.
   PubMed Web of Science ®Google Scholar
• Boyle RJ, Robins-Browne RM, Tang ML. Probiotic use in clinical practice: what are the risks? Am J Clin Nutr 2006;83:1256–1264.
   PubMed Web of Science ®Google Scholar
• Lyons A, O'Mahony D, O'Brien F, MacSharry J, Sheil B, Ceddia M, et al. Bacterial strain-specific induction of Foxp3+ T regulatory cells is protective in murine allergy models. Clin Exp Allergy 2010;40:811–819.
   PubMed Web of Science ®Google Scholar
• Lee J, Bang J, Woo HJ. Immunomodulatory and anti-allergic effects of orally administered Lactobacillus species in ovalbumin-sensitized mice. J Microbiol Biotechnol 2013;23:724–730. doi:10.4014/jmb.1211.11079
   PubMed Web of Science ®Google Scholar
• Huang R, Ning H, Shen M, Li J, Zhang J, Chen X. Probiotics for the treatment of atopic dermatitis in children: a systematic review and meta-analysis of randomized controlled trials. Front Cell Infect Microbiol 2017;7:392.
   PubMed Web of Science ®Google Scholar
• Spacova I, Petrova MI, Fremau A, Pollaris L, Vanoirbeek J, Ceuppens JL, et al. Intranasal administration of probiotic Lactobacillus rhamnosus GG prevents birch pollen-induced allergic asthma in a murine model. Allergy 2018. [Epub ahead of print]. doi:10.1111/all.13502
   Web of Science ®Google Scholar
• Forsythe P, Inman MD, Bienenstock J. Oral treatment with live Lactobacillus reuteri inhibits the allergic airway response in mice. Am J Respir Crit Care Med 2007;175:561–569. doi:10.1164/rccm.200606-821OC
   PubMed Web of Science ®Google Scholar
• Hougee S, Vriesema AJM, Wijering SC, Knippels LMJ, Folkerts G, Nijkamp FP, Knol J, et al. Oral treatment with probiotics reduces allergic symptoms in ovalbumin-sensitized mice: a bacterial strain comparative study. Int Arch Allergy Immunol 2010;151:107–117. doi:10.1159/000236000
   PubMed Web of Science ®Google Scholar