302
Views
2
CrossRef citations to date
0
Altmetric
Biomarkers

Severe asthma in adult, inner-city predominantly African–American and latinx population: demographic, clinical and phenotypic characteristics

, MBBS, , MD, , MD, , MD, MPH, , DO, , MD, MSORCID Icon & , MD show all
Pages 2341-2351 | Received 09 Jun 2021, Accepted 21 Nov 2021, Published online: 02 Dec 2021

References

  • https://www.cdc.gov/asthma/most_recent_data_states.htm.
  • https://www.health.ny.gov/statistics/ny_asthma/data/2016eh/a19.htm.
  • https://www.health.ny.gov/statistics/ny_asthma/data/2016eh/a9.htm.
  • “New York State Asthma Surveillance Summary Report”. New York State Department of Health, Public Health Information Group Center for Community Health. 2013 Oct.
  • “An Economic Snapshot of the Bronx”. Office of the New York State Comptroller. 2018 Jul.
  • Rastogi D, Madhok N, Kipperman S. Caregiver asthma knowledge, aptitude, and practice in high healthcare utilizing children: effect of an educational intervention. Pediatr Allergy Immunol Pulmonol. 2013;26(3):128–139. doi:10.1089/ped.2013.0226.
  • Schlender A, Alperin PE, Grossman HL, Sutherland ER. Modeling the impact of increased adherence to asthma therapy. PLoS One. 2012;7(12):e51139. doi:10.1371/journal.pone.0051139.
  • Iyad Kheirbek KW, Walters S, Pezeshki G, Kass D. Air pollution and the health of New Yorkers: the impact of fine particles and ozone.
  • Nathan RA, Sorkness CA, Kosinski M, Schatz M, Li JT, Marcus P, Murray JJ, Pendergraft TB. Development of the asthma control test: a survey for assessing asthma control. J Allergy Clin Immunol. 2004;113(1):59–65. doi:10.1016/j.jaci.2003.09.008.
  • Kroenke K, Spitzer RL, Williams JB. The PHQ-9: validity of a brief depression severity measure. J Gen Intern Med. 2001;16(9):606–613. doi:10.1046/j.1525-1497.2001.016009606.x.
  • Asthma GRGSf, style="margin-left:19.65pt MaPAahgor-g-r-g-s-f-a-m-a-ppcM, mso-add-space:auto, text-indent:-19.65pt, line-height:200%, lfo2"> m-lll.
  • Heinzerling L, Mari A, Bergmann K-C, Bresciani M, Burbach G, Darsow U, Durham S, Fokkens W, Gjomarkaj M, Haahtela T, et al. The skin prick test - European standards. Clin Transl Allergy. 2013;3(1):3. doi:10.1186/2045-7022-3-3.
  • Oppenheimer J, Nelson HS. Skin testing. Ann Allergy Asthma Immunol. 2006;96(2):S6–S12. doi:10.1016/S1081-1206(10)60895-2.
  • Ciprandi G, Schiavetti I, Rindone E, Ricciardolo FL. The impact of anxiety and depression on outpatients with asthma. Ann Allergy Asthma Immunol. 2015;115(5):408–414. doi:10.1016/j.anai.2015.08.007.
  • Holguin F, Bleecker ER, Busse WW, Calhoun WJ, Castro M, Erzurum SC, Fitzpatrick AM, Gaston B, Israel E, Jarjour NN, et al. Obesity and asthma: an association modified by age of asthma onset. J Allergy Clin Immunol. 2011;127(6):1486–1493.e2. doi:10.1016/j.jaci.2011.03.036.
  • Moore WC, Bleecker ER, Curran-Everett D, Erzurum SC, Ameredes BT, Bacharier L, Calhoun WJ, Castro M, Chung KF, Clark MP, et al. Characterization of the severe asthma phenotype by the National Heart, Lung, and Blood Institute’s Severe Asthma Research Program. J Allergy Clin Immunol. 2007;119(2):405–413. doi:10.1016/j.jaci.2006.11.639.
  • Zein JG, Denson JL, Wechsler ME. Asthma over the adult life course: gender and hormonal influences. Clin Chest Med. 2019;40(1):149–161. doi:10.1016/j.ccm.2018.10.009.
  • Chipps BE, Zeiger RS, Borish L, Wenzel SE, Yegin A, Hayden ML, Miller DP, Bleecker ER, Simons FER, Szefler SJ, et al. Key findings and clinical implications from The Epidemiology and Natural History of Asthma: Outcomes and Treatment Regimens (TENOR) study. J Allergy Clin Immunol. 2012;130(2):332–342.e10. doi:10.1016/j.jaci.2012.04.014.
  • European Network for Understanding Mechanisms of Severe Asthma. The ENFUMOSA cross-sectional European multicentre study of the clinical phenotype of chronic severe asthma. Eur Respir J. 2003;22(3):470–477.
  • Rastogi D, Suzuki M, Greally JM. Differential epigenome-wide DNA methylation patterns in childhood obesity-associated asthma. Sci Rep. 2013;3:2164. doi:10.1038/srep02164.
  • Peters U, Dixon AE, Forno E. Obesity and asthma. J Allergy Clin Immunol. 2018;141(4):1169–1179. doi:10.1016/j.jaci.2018.02.004.
  • Bardach NS, Neel C, Kleinman LC, McCulloch CE, Thombley R, Zima BT, Grupp-Phelan J, Coker TR, Cabana MD. Depression, anxiety, and emergency department use for asthma. Pediatrics. 2019;144(4):e20190856. doi:10.1542/peds.2019-0856.
  • Galić K, Dodaj A, Ćorluka-Čerkez V, Lasic V, Pejić R, Šimić J, Vukojević M. Study of depression and anxiety in patients with asthma and chronic obstructive pulmonary disease. Psychiatr Danub. 2019;31(Suppl 1):112–117.
  • Boutin-Forzano S, Hammou Y, Gouitaa M, Charpin D. Air pollution and atopy. Eur Ann Allergy Clin Immunol. 2005;37(1):11–16.
  • Sbihi H, Allen RW, Becker A, Brook JR, Mandhane P, Scott JA, Sears MR, Subbarao P, Takaro TK, Turvey SE, et al. Perinatal exposure to traffic-related air pollution and atopy at 1 year of age in a multi-center Canadian birth cohort study. Environ Health Perspect. 2015;123(9):902–908. doi:10.1289/ehp.1408700.
  • A. WHOWBo. 2011-2012 Executive Summary. By Prof. Ruby Pawankar M, PhD, Prof. Giorgio, Walkter Canonica M, Prof. Stephen T. Holgate, BSc, MD, DSc, FMed Sci and, Prof. Richard F. Lockey M.
  • Burbank AJ, Grabich SC, Todorich K, Frye M, Loughlin C, Duncan K, Robinette C, Mills K, Peden DB, Diaz-Sanchez D, et al. Effect of aeroallergen sensitization on asthma control in African American teens with persistent asthma. Ann Allergy Asthma Immunol. 2016;117(4):442–444. doi:10.1016/j.anai.2016.07.041.
  • Hersh CP, Zacharia S, Prakash Arivu Chelvan R, Hayden LP, Mirtar A, Zarei S, Putcha N. Immunoglobulin E as a biomarker for the overlap of atopic asthma and chronic obstructive pulmonary disease. Chronic Obstr Pulm Dis. 2020;7(1):1–12. doi:10.15326/jcopdf.7.1.2019.0138.
  • Dogru M. Investigation of asthma comorbidity in children with different severities of allergic rhinitis. Am J Rhinol Allergy. 2016;30(3):186–189. doi:10.2500/ajra.2016.30.4315.
  • Leynaert B, Neukirch F, Demoly P, Bousquet J. Epidemiologic evidence for asthma and rhinitis comorbidity. J Allergy Clin Immunol. 2000;106(5 Suppl):S201–S5. doi:10.1067/mai.2000.110151.
  • Guerra S, Sherrill DL, Martinez FD, Barbee RA. Rhinitis as an independent risk factor for adult-onset asthma. J Allergy Clin Immunol. 2002;109(3):419–425. doi:10.1067/mai.2002.121701.
  • Higuchi O, Adachi Y, Itazawa T, Ito Y, Yoshida K, Ohya Y, Odajima H, Akasawa A, Miyawaki T. Rhinitis has an association with asthma in school children. Am J Rhinol Allergy. 2013;27(1):e22–5. doi:10.2500/ajra.2013.27.3846.
  • Mener DJ, Lin SY. Improvement and prevention of asthma with concomitant treatment of allergic rhinitis and allergen-specific therapy. Int Forum Allergy Rhinol. 2015;5(Suppl 1):S45–S50. doi:10.1002/alr.21569.
  • Spergel JM, Paller AS. Atopic dermatitis and the atopic march. J Allergy Clin Immunol. 2003;112(6 Suppl):S118–S27. doi:10.1016/j.jaci.2003.09.033.
  • Roberts G, Patel N, Levi-Schaffer F, Habibi P, Lack G. Food allergy as a risk factor for life-threatening asthma in childhood: a case-controlled study. J Allergy Clin Immunol. 2003;112(1):168–174. doi:10.1067/mai.2003.1569.
  • Priftis KN, Mermiri D, Papadopoulou A, Papadopoulos M, Fretzayas A, Lagona E. Asthma symptoms and bronchial reactivity in school children sensitized to food allergens in infancy. J Asthma. 2008;45(7):590–595. doi:10.1080/02770900802032941.
  • O’Byrne PM, Barnes PJ, Rodriguez-Roisin R, Runnerstrom E, Sandstrom T, Svensson K, Tattersfield A. Low dose inhaled budesonide and formoterol in mild persistent asthma: the OPTIMA randomized trial. Am J Respir Crit Care Med. 2001;164(8 Pt 1):1392–1397. doi:10.1164/ajrccm.164.8.2104102.
  • Pauwels RA, Pedersen S, Busse WW, Tan WC, Chen Y-Z, Ohlsson SV, Ullman A, Lamm CJ, O’Byrne PM. Early intervention with budesonide in mild persistent asthma: a randomised, double-blind trial. Lancet. 2003;361(9363):1071–1076. doi:10.1016/S0140-6736(03)12891-7.
  • Adams NP, Bestall JB, Malouf R, Lasserson TJ, Jones PW. Inhaled beclomethasone versus placebo for chronic asthma. Cochrane Database Syst Rev. 2005;(1):CD002738.
  • Suissa S, Ernst P, Benayoun S, Baltzan M, Cai B. Low-dose inhaled corticosteroids and the prevention of death from asthma. N Engl J Med. 2000;343(5):332–336. doi:10.1056/NEJM200008033430504.
  • Hosseini M, Almasi-Hashiani A, Sepidarkish M, Maroufizadeh S. Global prevalence of asthma-COPD overlap (ACO) in the general population: a systematic review and meta-analysis. Respir Res. 2019;20(1):229. doi:10.1186/s12931-019-1198-4.
  • Barbee RA, Halonen M, Lebowitz M, Burrows B. Distribution of IgE in a community population sample: correlations with age, sex, and allergen skin test reactivity. J Allergy Clin Immunol. 1981;68(2):106–111. doi:10.1016/0091-6749(81)90167-6.
  • Wittig HJ, Belloit J, De Fillippi I, Royal G. Age-related serum immunoglobulin E levels in healthy subjects and in patients with allergic disease. J Allergy Clin Immunol. 1980;66(4):305–313. doi:10.1016/0091-6749(80)90026-3.
  • Austin D, Pouliquen I, Keene O, Yancey S. Blood eosinophil dose response to oral corticosteroids in a population of patients with severe asthma. Eur Respir J. 2019;48(suppl 60):PA11102016.
  • Ortega H, Llanos J-P, Lafeuille M-H, Duh MS, Germain G, Lejeune D, Sama S, Bell C, Hahn B. Effects of systemic corticosteroids on blood eosinophil counts in asthma: real-world data. J Asthma. 2019;56(8):808–815. doi:10.1080/02770903.2018.1502301.
  • Buhl R, Humbert M, Bjermer L, Chanez P, Heaney LG, Pavord I, Quirce S, Virchow JC, Holgate S. Severe eosinophilic asthma: a roadmap to consensus. Eur Respir J. 2017;49(5):1700634. doi:10.1183/13993003.00634-2017.
  • Miranda C, Busacker A, Balzar S, Trudeau J, Wenzel SE. Distinguishing severe asthma phenotypes: role of age at onset and eosinophilic inflammation. J Allergy Clin Immunol. 2004;113(1):101–108. doi:10.1016/j.jaci.2003.10.041.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.