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Research Article

Identification of two hub genes and miRNA‑mRNA interactions in chronic obstructive pulmonary disease (COPD) plasma

, MM, , BM, , BM & , BM
Received 02 Dec 2023, Accepted 25 Feb 2024, Published online: 07 Mar 2024

References

  • Agustí A, Hogg JC. Update on the pathogenesis of chronic obstructive pulmonary disease. N Engl J Med. 2019;381(13):1248–1256. doi:10.1056/NEJMra1900475.
  • Brightling C, Greening N. Airway inflammation in COPD: progress to precision medicine. Eur Respir J. 2019;54(2):1900651. doi:10.1183/13993003.00651-2019.
  • Zhu M, Ye M, Wang J, Ye L, Jin M. Construction of potential miRNA-mRNA regulatory network in COPD plasma by bioinformatics analysis. Int J Chron Obstruct Pulmon Dis. 2020;15:2135–2145. doi:10.2147/COPD.S255262.
  • Singh D, Roche N, Halpin D, Agusti A, Wedzicha JA, Martinez FJ. Current controversies in the pharmacological treatment of chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2016;194(5):541–549. doi:10.1164/rccm.201606-1179PP.
  • Lindberg A, Eriksson B, Larsson L-G, Rönmark E, Sandström T, Lundbäck B. Seven-year cumulative incidence of COPD in an age-stratified general population sample. CHEST. 2006;129(4):879–885. doi:10.1378/chest.129.4.879.
  • Lokke A, Lange P, Scharling H, Fabricius P, Vestbo J. Developing COPD: a 25 year follow up study of the general population. THORAX. 2006;61(11):935–939. doi:10.1136/thx.2006.062802.
  • Ambros V. The functions of animal microRNAs. Nature. 2004;431(7006):350–355. doi:10.1038/nature02871.
  • Lim LP, Lau NC, Garrett-Engele P, Grimson A, Schelter JM, Castle J, Bartel DP, Linsley PS, Johnson JM. Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs. Nature. 2005;433(7027):769–773. doi:10.1038/nature03315.
  • Bartel DP. MicroRNAs: target recognition and regulatory functions. CELL. 2009;136(2):215–233. doi:10.1016/j.cell.2009.01.002.
  • Wittstatt J, Weider M, Wegner M, Reiprich S. MicroRNA miR-204 regulates proliferation and differentiation of oligodendroglia in culture. GLIA. 2020;68(10):2015–2027. doi:10.1002/glia.23821.
  • Conickx G, Mestdagh P, Avila Cobos F, Verhamme FM, Maes T, Vanaudenaerde BM, Seys LJM, Lahousse L, Kim RY, Hsu AC, et al. MicroRNA profiling reveals a role for MicroRNA-218-5p in the pathogenesis of chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2017;195(1):43–56. doi:10.1164/rccm.201506-1182OC.
  • Schembri F, Sridhar S, Perdomo C, Gustafson AM, Zhang X, Ergun A, Lu J, Liu G, Zhang X, Bowers J, et al. MicroRNAs as modulators of smoking-induced gene expression changes in human airway epithelium. Proc Natl Acad Sci U S A. 2009;106(7):2319–2324. doi:10.1073/pnas.0806383106.
  • Sato T, Liu X, Nelson A, Nakanishi M, Kanaji N, Wang X, Kim M, Li Y, Sun J, Michalski J, et al. Reduced miR-146a increases prostaglandin E-2 in chronic obstructive pulmonary disease fibroblasts. Am J Respir Crit Care Med. 2010;182(8):1020–1029. doi:10.1164/rccm.201001-0055OC.
  • Castillo D, Burgos F, Guayta R, Giner J, Lozano P, Estrada M, Soriano JB, Flor X, Barau M, Casan P, et al. Airflow obstruction case finding in community-pharmacies: a novel strategy to reduce COPD underdiagnosis. Respir Med. 2015;109(4):475–482. doi:10.1016/j.rmed.2015.02.009.
  • Davis KJ, Landis SH, Oh Y-M, Mannino DM, Han MK, van der Molen T, Aisanov Z, Menezes AM, Ichinose M, Muellerova H, et al. Continuing to confront COPD international physician survey: physician knowledge and application of COPD management guidelines in 12 countries. Int J Chron Obstruct Pulmon Dis. 2015;10:39–55. doi:10.2147/COPD.S70162.
  • Burney P, Jarvis D, Perez-Padilla R. The global burden of chronic respiratory disease in adults. Int J Tuberc Lung Dis. 2015;19(1):10–20. doi:10.5588/ijtld.14.0446.
  • Halldin CN, Doney BC, Hnizdo E. Changes in prevalence of chronic obstructive pulmonary disease and asthma in the US population and associated risk factors. Chron Respir Dis. 2015;12(1):47–60. doi:10.1177/1479972314562409.
  • Anzueto A, Sethi S, Martinez FJ. Exacerbations of chronic obstructive pulmonary disease. Proc Am Thorac Soc. 2007;4(7):554–564. doi:10.1513/pats.200701-003FM.
  • Melville AM, Pless-Mulloli T, Afolabi OA, Stenton SC. COPD prevalence and its association with occupational exposures in a general population. Eur Respir J. 2010;36(3):488–493. doi:10.1183/09031936.00038309.
  • Jensen HH, Godtfredsen NS, Lange P, Vestbo J. Potential misclassification of causes of death from COPD. Eur Respir J. 2006;28(4):781–785. doi:10.1183/09031936.06.00152205.
  • Zhou Y, Zou Y, Li X, Chen S, Zhao Z, He F, Zou W, Luo Q, Li W, Pan Y, et al. Lung function and incidence of chronic obstructive pulmonary disease after improved cooking fuels and kitchen ventilation: a 9-year prospective cohort study. PLoS Med. 2014;11(3):e1001621. doi:10.1371/journal.pmed.1001621.
  • López-Campos JL, Ruiz-Ramos M, Soriano JB. Mortality trends in chronic obstructive pulmonary disease in Europe, 1994-2010: a joinpoint regression analysis. Lancet Respir Med. 2014;2(1):54–62. doi:10.1016/S2213-2600(13)70232-7.
  • Eisner MD, Anthonisen N, Coultas D, Kuenzli N, Perez-Padilla R, Postma D, Romieu I, Silverman EK, Balmes JR, Committee on Nonsmoking COPD, Environmental and Occupational Health Assembly An official American thoracic society public policy statement: novel risk factors and the global burden of chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2010;182(5):693–718. doi:10.1164/rccm.200811-1757ST.
  • Postma DS, Bush A, van den Berge M. Risk factors and early origins of chronic obstructive pulmonary disease. Lancet. 2015;385(9971):899–909. doi:10.1016/S0140-6736(14)60446-3.
  • Sun XJ, Chen L, He ZY. PI3K/Akt-Nrf2 and anti-inflammation effect of macrolides in chronic obstructive pulmonary disease. Curr Drug Metab. 2019;20(4):301–304. doi:10.2174/1389200220666190227224748.
  • Li YL. The role of the PI3K/AKT/mTOR protein synthesis pathway in the skeletal muscle atrophy induced by COPD. Int J Clin Exp Med. 2016;9(3):5677–5687.
  • Zhang HX, et al. HIF-1 alpha promotes inflammatory response of chronic obstructive pulmonary disease by activating EGFR/PI3K/AKT pathway. Eur Rev Med Pharmacol Sci. 2018;22(18):6077–6084.
  • Wang L, Jiang W, Wang J, Xie Y, Wang W. Puerarin inhibits FUNDC1-mediated mitochondrial autophagy and CSE-induced apoptosis of human bronchial epithelial cells by activating the PI3K/AKT/mTOR signaling pathway. Aging (Albany NY). 2022;14(3):1253–1264. doi:10.18632/aging.203317.
  • Shi J, Ye J, Fei H, Jiang S-H, Wu Z-Y, Chen Y-P, Zhang L-W, Yang X-M. YWHAZ promotes ovarian cancer metastasis by modulating glycolysis. Oncol Rep. 2019;41(2):1101–1112. doi:10.3892/or.2018.6920.
  • Liu W, Hu W, Hou K, Zhu S. Circular RNA paired-related homeobox 1 promotes gastric carcinoma cell progression via regulating microRNA-665/YWHAZ axis. Dig Dis Sci. 2021;66(11):3842–3853. doi:10.1007/s10620-020-06705-5.
  • Deng Y, Zheng JY, Ma JG. The clinical and prognostic significance of YWHAZ in non-small-cell lung cancer patients: immunohistochemical analysis. J Cell Biochem. 2019;120(4):6290–6298. doi:10.1002/jcb.27915.
  • Shen Z, Chai T, Luo F, Liu Z, Xu H, Zhang P, Kang M, Chen S. Loss of miR-204-5p promotes tumor proliferation, migration, and invasion through targeting YWHAZ/PI3K/AKT pathway in esophageal squamous cell carcinoma. Onco Targets Ther. 2020;13:4679–4690. doi:10.2147/OTT.S243215.
  • Guo C, Liu S, Wang J, Sun M-Z, Greenaway FT. ACTB in cancer. Clin Chim Acta. 2013;417:39–44. doi:10.1016/j.cca.2012.12.012.
  • Gu Y, Tang S, Wang Z, Cai L, Lian H, Shen Y, Zhou Y. A pan-cancer analysis of the prognostic and immunological role of beta-actin (ACTB) in human cancers. Bioengineered. 2021;12(1):6166–6185. doi:10.1080/21655979.2021.1973220.
  • Li Y, Ma H, Shi C, Feng F, Yang L. Mutant ACTB mRNA 3 ‘-UTR promotes hepatocellular carcinoma development by regulating miR-1 and miR-29a. Cell Signal. 2020;67:109479. doi:10.1016/j.cellsig.2019.109479.
  • Ito M, Hiwasa T, Yajima S, Suzuki T, Oshima Y, Nanami T, Sumazaki M, Shiratori F, Li S-Y, Iwadate Y, et al. Low anti-CFL1 antibody with high anti-ACTB antibody is a poor prognostic factor in esophageal squamous cell carcinoma. Esophagus. 2022;19(4):617–625. doi:10.1007/s10388-022-00939-0.
  • Sun C, Zhou T, Xie G, Fu S, Gao L, Liao J, Wu Y, Wang G. Proteomics of exhaled breath condensate in stable COPD and non-COPD controls using tandem mass tags (TMTs) quantitative mass spectrometry: a pilot study. J Proteomics. 2019;206:103392. doi:10.1016/j.jprot.2019.103392.
  • Liu T. miR-937 serves as an inflammatory inhibitor in cigarette smoke extract-induced human bronchial epithelial cells by targeting IL1B and regulating TNF-alpha/IL-17 signaling pathway. Tob Induc Dis. 2021;19(July). doi:10.18332/tid/138227.
  • Cao Z, et al. microRNA-183 down-regulates the expression of BKCa beta 1 protein that is related to the severity of chronic obstructive pulmonary disease. Hippokratia. 2014;18(4):328–332.
  • Wang XD, et al. Resveratrol inhibits dysfunction of dendritic cells from chronic obstructive pulmonary disease patients through promoting miR-34. Int J Clin Exp Path. 2015;8(5):5145–5152.
  • Wang C, Feng D, Dong S, He R, Fan B. Dysregulated circulating microRNA-126 in chronic obstructive pulmonary disease: linkage with acute exacerbation risk, severity degree, and inflammatory cytokines. J Clin Lab Anal. 2022;36(3):e24204. doi:10.1002/jcla.24204.

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