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Original Articles

Combined effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin and polychlorinated biphenyl congeners in rats

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Pages 71-87 | Received 26 May 2006, Accepted 26 Jul 2006, Published online: 03 Dec 2010

References

  • Haschek , Wanda M , Rousseaux , CG and Wallig , MA . 2002 . Handbook of toxicologic pathology. , 2nd Edn , San Diego, CA : Academic Press .
  • De Rosa , CT , El-Masri , HA , Pohl , H , Cibulus , W and Mumtaz , MM . 2004 . Implications of chemical mixtures in public health practice . J. Toxicol. Environ. Health Part B , 7 : 339 – 350 .
  • Anonymous . 1986 . Guidelines for chemical mixtures. Federal Register. ;51FR [September 25] 34014 – 34029 .
  • Yang , RS , el-Masri , HA , Thomas , RS , Constan , AA and Tessari , JD . 1995 . The application of physiologically based pharmacokinetic/pharmacodynamic (PBPK/PD) modeling for exploring risk assessment approaches of chemical mixtures . Toxicol. Lett. , 79 : 193 – 200 .
  • Harper , N , Connor , K , Steinberg , M and Safe , S . 1995 . Immunosuppressive activity of polychlorinated biphenyl mixtures and congeners: Non-additive (antagonistic) interactions . Fundam. Appl. Toxicol. , 27 : 131 – 139 .
  • Chu , I , Villeneuve , DC , Yagminas , A , Lecavalier , P , Håkansson , H , Ahlborg , UG , Valli , VE , Kennedy , SW , Bergman , A , Seegal , RF and Feeley , M . 1995a . Toxicity of PCP 77 (3,3′,4,4′-tetrachlorobiphenyl) and PCB 118 (2,3′,4,4′,5-pentachlorobiphenyl) in the rat following subchronic dietary exposure . Fundam. Appl. Toxicol. , 26 : 282 – 292 .
  • Chu , I , Villeneuve , DC , Yagminas , A , Lecavalier , PL , Poon , R , Feeley , M , Kennedy , SW , Seegal , RF , Kansson , H , Ahlborg , UG and Valli , VE . 1995b . Subchronic toxicity of 3,3′,4,4′,5-pentachlorobiphenyl in the rat. I. Clinical, biochemical, hematological, and histopathological changes . Fundam. Appl. Toxicol. , 22 : 457 – 468 .
  • Mes , JD , Davies , J , Doucet Weber , J and McMullen , E . 1993 . Specific polychlorinated biphenyl congeners distribution in breast milk of Canadian women . Environ. Technol. , 14 : 555 – 565 .
  • Newsome , WH and Andrews , P . 1993 . Organochlorine pesticides and polychlorinated biphenyl congeners in commercial fish from the Great Lakes . J. Assoc. Offic. Anal. Chem. , 76 : 707 – 710 .
  • Bergman , A , Nillson , A , Riego , A and Orn , U . 1990 . Synthesis of 14C labelled and unlabelled coplanar polychlorinated biphenyls (PCBs) . Acta Chem. Scand. , 44 : 1071 – 1076 .
  • Olfert , E , Cross , B and McWilliam , A . 1993 . Guide to the care and use of experimental animals , 2nd , Ottawa, ON : Canadian Council on Animal Care .
  • Burke , MD , Thompson , S , Elcombe , CR , Halpert , J , Haaparanta , T and Mayer , RT . 1985 . Ethoxy- pentoxy- and benzyloxy-phenoazones and homologues: A series of substrates to distinguish between different induced cytochrome P-450s . Biochem. Pharmacol. , 34 : 3337 – 3345 .
  • Lubet , RA , Nims , RW , Mayer , RT , Cameron , JW and Schechtman , LM . 1985 . Measurement of cytochrome P-450 dependent dealkylation of alkoxyphenoxazones in hepatic S9 and hepatocyte homogenate: Effects of dicumarol . Mutat. Res. , 142 : 127 – 131 .
  • Burchell , B and Wetherill , P . 1981 . “ 4-Nitrophenol UDP-glucuronyltransferase (rat liver) ” . In Methods in enzymology , Edited by: Jakoby , WB and William , B . Vol. 77 , 169 – 171 . New York, NY : Academic Press .
  • Habig , WH , Pabst , MJ and Jacoby , WB . 1974 . Glutathione-S-transferase: The first enzymatic step in mercapturic acid formation . J. Biol. Chem. , 248 : 7130 – 7139 .
  • Poon , R , Chu , I , Lecavalier , P , Bergman , A and Villeneuve , DC . 1994 . Urinary ascorbic acid-HPLC determination and application as a non-invasive biomarker of hepatic response . J. Biochem. Toxicol. , 9 : 297 – 304 .
  • Hakansson , H , Waern , F and Ahlborg , HG . 1987 . Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in the lactating rat on maternal and neonatal vitamin A status . J. Nutr. , 117 : 580 – 586 .
  • Chu , I , Lecavalier , P , Håkanson , H , Yagminas , A , Valli , VE , Poon , P and Feeley , M . 2001 . Combined Effects of 2,3,7,8-tetrachlorodibenzo-p-doxin and polychlorinated biphenyls congeners in rats . Chemosphere , 43 : 807 – 814 .
  • Kiernan , JA . 1999 . Histological and histochemical methods: Theory and practice. , New York, NY : Oxford University Press .
  • Bemis , JC , Nazarenko , DA and Gasiewicz , TA . 2005 . Coplanar polychlorinated biphenyls activate the aryl hydrocarbon receptor in developing tissues of two TCDD-responsive lacZ mouse lines . Toxicol. Sci. , 87 : 529 – 536 .
  • Van der Plas , S , de Jongh , J , Faassen-Peters , M , Scheu , G , van den Berg , M and Brouwer , A . 1998 . Toxicokinetics of an environmentally relevant mixture of dioxin-like PAHs with or without a non-dioxin like PCB in a semi-chronic exposure study in female Sprague Dawley rats . Chemosphere , 37 : 1941 – 1955 .
  • Van der Kolk , J , van Birgelen , APJM , Poiger , H and Schlatter , C . 1992 . Interactions of 2,2′,4,4′,5,5′-hexachlorobiphenyl and 2,3,7,8-tetrachlorodibenzo-p-dioxin in a subchronic feeding study in the rat . Chemosphere , 25 : 2023 – 2027 .
  • Bannister , R , Davis , D , Zacharewski , T , Tizard , I and Safe , S . 1987 . Aroclor 1254 as a 2,3,7,8-tetrachlorodibenzo-p-dioxin antagonist: Effects on enzyme induction and immunotoxicity . Toxicology , 46 : 29 – 42 .
  • Haake , JM , Safe , S , Mayura , K and Philips , TD . 1987 . Aroclor as an antagonist of the teratogenicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin . Toxicol. Lett. , 38 : 299 – 306 .
  • Morrisey , RE , Harris , MW , Diliberto , JJ and Birnbaum , LS . 1992 . Limited PCB antagonism of TCDD-induced malformations in mice . Toxicol. Lett. , 60 : 19 – 25 .
  • Van Birgelen , APJM , van der Kolk , J , Poiger , H , van den Berg , M and Brouwer , A . 1992 . Interactive effects of 2,2′,4,4′,5,5′-hexachlorobiphenyl 2,3,7,8-tetrachlorodibenzo-p-dioxin on thyroid hormone, vitamin A and vitamin K metabolism in rats . Chemosphere , 25 : 1239 – 1244 .
  • Van Birgelen , APJM , Fase , KM , Poiger , H , van der Kolk , J , Brouwer , A , Seinen , W and van der Berg , M . 1996 . Synergistic effect of 2,2′,4,4′,5,5′-hexachlorobiphenyl and 2,3,7,8-tetrachlorodibenzo-p-dioxin on porphyrin levels in the rat . Environ. Health Perspect. , 104 : 550 – 557 .
  • Albro , PW , Corbett , JT , Harris , M and Lawson , LD . 1978 . Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on lipid profiles in tissue of the Fischer rat . Chem. Biol. Interact. , 23 : 315 – 330 .
  • DiBatolomeis , MJ , Moore , RW , Peterson , RE and Jefcoate , CR . 1986 . Hypercholesterolemia and regulation of adrenal steroidogenesis in 2,3,7,8-tetrachlorodibenzo-p-dioxin treated rats . Toxicol. Appl. Pharmacol. , 85 : 313 – 323 .
  • Oda , H , Matsushita , N , Hirabayashi , A and Yoshida , A . 1990 . Hyperlipoproteinemia in rats fed polychlorinated biphenyls . J. Nutr. Sci. Vitamol. , 36 : 117 – 122 .
  • Olsen , H , Enan , E and Matsumura , F . 1998 . 2,3,7,8-Tetrachlorodibenzo-p-dioxin mechanism of action to reduce lipoprotein lipase activity in the 3T3-L1 preadipocyte cell line . J. Biochem. Mol. Toxicol. , 12 : 29 – 39 .
  • Munzel , PA , Bruck , M and Brock , KW . 1994 . Tissue-specific constitutive and inducible expression of rat phenol UDP-glucuronosyltransferase . Biochem. Pharmacol. , 47 : 1445 – 1448 .
  • Kociba , RJ , Keeler , PA , Park , CN and Gehring , PJ . 1976 . 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD): Results of a 13-week oral toxicity study in rats . Toxicol. Appl. Pharmacol. , 35 : 553 – 574 .
  • Grinwis , GC , Vethaak , AD , Wester , PW and Vos , JG . 2000 . Toxicology of environmental chemicals in the flounder (Platichthys flesus) with emphasis on the immune system: Field, semi-field (mesocosm) and laboratory studies . Toxicol. Lett. , 15 : 289 – 301 .
  • Niittynen , M , Tuomisto , JT , Auriola , S , Pohjanvirta , R , Syrjälä , P , Simanainen , U , Viluksela , M and Tuomisto , J . 2003 . 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD)-induced accumulation of biliverdin and hepatic peliosis in rats . Toxicol. Sci. , 71 : 112 – 123 .
  • Schuur , Ag , Boekhorst , FM , Brouwer , A and Visser , TJ . 1997 . Extrathyroidal effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on thyroid hormone turnover in male Sprague-Dawley rats . Endocrinology , 138 : 3727 – 3734 .
  • Kamath , AB , Xu , H , Nagarkatti , PS and Nagarkatti , M . 1997 . Evidence for the induction of apoptosis in thymocytes by 2,3,7,8-tetrachlorodibenzo-p-dioxin in vivo . Toxicol. Appl. Pharmacol. , 142 : 367 – 377 .
  • Fernandez-Salguero , PM , Hilbert , DM , Rudikoff , S , Ward , JM and Gonzalez , FJ . 1996 . Aryl-hydrocarbon receptor-deficient mice are resistant to 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced toxicity . Toxicol. Appl. Pharmacol. , 140 : 173 – 179 .
  • Bastomsky , CH . 1977 . Enhanced thyroxine metabolism and high uptake goiters in rats after a single dose of 2,3,7,8-tetrachlorodibenzo-p-dioxin . Endocrinology , 101 : 292 – 296 .
  • Petroff , BK , Gao , X , Rozman , KK and Terranova , PF . 2000 . Interaction of estradiol and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in an ovulation model: Evidence for systemic potentiation and local ovarian effects . Reprod. Toxicol. , 4 : 247 – 255 .
  • Balk , JL and Piper , WN . 1984 . Altered blood levels of corticosteroids in the rat after exposure to 2,3,7,8-tetra-chlorodibenzo-p-dioxin . Biochem. Pharmacol. , 33 : 2531 – 2534 .
  • Birnbaum , LS , Harris , MW , Miller , CP , Pratt , RM and Lamb , JC . 1986 . Synergistic interaction of 2,3,7,8-tetra-chlorodibenzo-p-dioxin and hydrocortisone in the induction of cleft palate in mice . Teratology , 33 : 29 – 35 .

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