45
Views
0
CrossRef citations to date
0
Altmetric
Original Articles

Feasibility of metabolic parameter estimation in pharmacokinetic models of carbon tetrachloride exposure in ratsFootnote1

, , , , , & show all
Pages 521-546 | Received 31 Jan 2008, Accepted 29 Apr 2008, Published online: 05 May 2009

References

  • Allen , BC and Fisher , JW . 1993 . Pharmacokinetic modeling of trichloroethylene and trichloroacetic acid in humans . Risk Analysis , 13 : 71 – 86 .
  • Banks , HT , Ma , Y and Potter , LK . 2005 . A simulation-based comparison between parametric and nonparametric estimation methods in PBPK models . Journal of Inverse and Ill-Posed Problems , 13 : 1 – 26 .
  • Borggaard , J and Verma , A . 2000 . On efficient solutions to the continuous sensitivity equation using automatic differentiation . SIAM Journal on Scientific Computing , 22 : 39 – 62 .
  • Brown , RP , Delp , MD , Lindstedt , SL , Rhomberg , LR and Beliles , RP . 1997 . Physiological parameter values for physiologically based pharmacokinetic models . Toxicology and Industrial Health , 13 : 407 – 84 .
  • Clewell , HJ III , Gentry , PR , Covington , TR and Gearhart , JM . 2000 . Development of a physiologically based pharmacokinetic model of trichloroethylene and its metabolites for use in risk assessment . Environmental Health Perspectives , 108 ( Suppl 2 ) : 283 – 305 .
  • Cole , CE , Tran , HT and Schlosser , PM . 2001 . Physiologically based pharmacokinetic modeling of benzene metabolism in mice through extrapolation from in vitro to in vivo . Journal of Toxicology and Environmental Health A , 62 : 439 – 65 .
  • David , JA . 2007 . “ Optimal control, estimation, and shape design: Analysis and applications ” . In PhD thesis , (etd-07262007-194726) North Carolina State University .
  • El-Masri , H and Portier , CJ . 1998 . Physiologically based pharmacokinetics model of primidone and its metabolites phenobarbital and phenylethylmalonamide in humans, rats, and mice . Drug Metabolism and Disposition , 26 : 585 – 94 .
  • Evans , MV , Crank , WD , Yang , H-M and Simmons , JE . 1994 . Applications of a sensitivity analysis to a physiologically based pharmacokinetic model for carbon tetrachloride in rats . Toxicology and Applied Pharmacology , 128 : 36 – 44 .
  • Faroon , O , Taylor , J , Roney , N , Fransen , ME , Bogaczyk , S and Diamond , G . 2005 . Toxicological profile for carbon tetrachloride . Agency for Toxic Substances and Disease Registry , http://www.atsdr.cdc.gov/toxprofiles/tp30.pdf
  • Fisher , JW , Gargas , ML , Allen , BC and Andersen , ME . 1991 . Physiologically based pharmacokinetic modeling with trichloroethylene and its metabolite, trichloroacetic acid, in the rat and mouse . Toxicology and Applied Pharmacology , 109 : 183 – 95 .
  • Fisher , JW , Mahle , D and Abbas , R . 1998 . A human physiologically based pharmacokinetic model for trichloroethylene and its metabolites, trichloroacetic acid and free trichloroethanol . Toxicology and Applied Pharmacology , 152 : 339 – 59 .
  • Gallo , JM , Cheung , LL , Kim , HJ , Bruckner , JV and Gillespie , WR . 1993 . A physiological and system analysis hybrid pharmacokinetic model to characterize carbon tetrachloride blood concentrations following administration in different oral vehicles . Journal of Pharmacokinetics and Pharmacodynamics , 21 : 551 – 74 .
  • Gargas , ML , Andersen , ME and Clewell , HJ III . 1986 . A physiologically based simulation approach for determining metabolic constants from gas uptake data . Toxicology and Applied Pharmacology , 86 : 341 – 52 .
  • IRIS . 2007 . Status report for integrated risk information system (IRIS) chemical assessments . http://cfint.rtpnc.epa.gov/iristrac/index.cfm?fuseaction=listChemicals.showList, (accessed October 2007)
  • Kedderis , GL , Teo , SK , Batra , R , Held , SD and Gargas , ML . 1996 . Refinement and verification of the physiologically based dosimetry description for acrylonitrite in rats . Toxicology and Applied Pharmacology , 140 : 422 – 35 .
  • Loizou , GD . 2001 . The application of physiologically based pharmacokinetic modelling in the analysis of occupational exposure to perchloroethylene . Toxicology Letters , 124 : 59 – 69 .
  • Manibusan , MK , Odin , M and Eastmond , DA . 2007 . Postulated carbon tetrachloride mode of action: A review . Journal of Environmental Science and Health C , 25 : 185 – 209 .
  • Paustenbach , DJ , Clewell , HJ III , Gargas , ML and Andersen , ME . 1988 . A physiologically based pharmacokinetic model for inhaled carbon tetrachloride . Toxicology and Applied Pharmacology , 96 : 191 – 211 .
  • Ramsey , JC and Andersen , ME . 1984 . A physiologically based description of the inhalation pharmacokinetics of styrene in rats and humans . Toxicology and Applied Pharmacology , 73 : 159 – 75 .
  • Sanzgiri , U , Srivatsan , V , Muralidhara , S , Dallas , CE and Bruckner , JV . 1997 . Uptake, distribution, and elimination of carbon tetrachloride in rat tissues following inhalation and ingestion exposures . Toxicology and Applied Pharmacology , 143 : 120 – 9 .
  • Tardif , R , Charest-Tardif , G , Brodeur , J and Krishnan , K . 1997 . Physiologically based pharmacokinetic modeling of a ternary mixture of alkyl benzenes in rats and humans . Toxicology and Applied Pharmacology , 144 : 120 – 34 .
  • Tardif , R , Lapare , S , Charest-Tardif , G , Brodeur , J and Krishnan , K . 1995 . Physiologically-based pharmacokinetic modeling of a mixture of toluene and xylene in humans . Risk Analysis , 15 : 335 – 42 .
  • Thrall , KD and Kenny , DV . 1996 . Evaluation of a carbon tetrachloride physiologically based pharmacokinetic model using real-time breath analysis monitoring of the rat . Inhalation Toxicology , 8 : 251 – 61 .
  • Thrall , KD , Vucelick , ME , Gies , RA , Zangar , RC , Weitz , KK , Poet , TS , Springer , DL , Grant , DM and Benson , JM . 2000 . Comparative metabolism of carbon tetrachloride in rats, mice, and hamsters using gas uptake and PBPK modeling . Journal of Toxicology and Environmental Health A , 60 : 531 – 48 .
  • Timchalk , C , Nolan , RJ , Mendrala , AL , Dittenber , DA , Brzak , KA and Mattsson , JL . 2002 . A physiologically based pharmacokinetic and pharmacodynamic (PBPK/PD) model for the organophosphate insecticide chlorpyrifos in rats and humans . Toxicological Sciences , 66 : 34 – 53 .
  • U.S. Environmental Protection Agency . 2006 . Integrated risk information system (IRIS); announcement of 2006 program . Federal Register , 71 ( 97 ) : 29149 – 52 .
  • Yokley , KA and Evans , MV . 2007 . An example of model structure differences using sensitivity analyses in physiologically based pharmacokinetic models of trichloroethylene in humans . Bulletin of Mathematical Biology , 69 : 2591 – 625 .
  • Yokley , KA , Tran , H and Schlosser , PM . 2008 . Sensory irritation response in rats: Modeling, analysis and validation . Bulletin of Mathematical Biology , 70 : 555 – 88 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.