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Original Articles

Comparative in vitro metabolism of chloroxylenol, chlorophene, and triclosan with rat, mouse, and human hepatic microsomes

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Pages 1735-1747 | Received 22 Sep 2009, Accepted 11 Feb 2010, Published online: 13 Sep 2010

References

  • Adolfsson-Erici , M , Pettersson , M , Parkkonen , J and Sturve , J . 2002 . Triclosan, a commonly used bactericide found in human milk and in the aquatic environment in Sweden . Chemosphere , 46 : 1485 – 9 .
  • Bruch , MK . 1996 . “ Chloroxylenol: An old–new antimicrobial ” . In Handbook of disinfectants and antiseptics , Edited by: Ascenzi , JM . 265 – 94 . New York : Marcel Dekker, Inc .
  • Calafat , AM , Ye , X , Wong , LY , Reidy , JA and Needham , LL . 2008 . Urinary concentrations of triclosan in the U.S. population: 2003–2004 . Environmental Health Perspectives , 116 : 303 – 7 .
  • Dorantes , A and Stavchansky , S . 1992 . Pharmacokinetic and metabolic disposition of p-chloro-m-xylenol (PCMX) in dogs . Pharmaceutical Research , 9 : 677 – 82 .
  • Foran , CM , Bennett , ER and Benson , WH . 2000 . Developmental evaluation of a potential non-steroidal estrogen: Triclosan . Marine Environmental Research , 50 : 153 – 6 .
  • Groves , JT and Han , Y-Z . 1995 . “ Models and mechanisms of cytochrome P450 action ” . In Cytochrome P450: Structure, mechanism and biochemistry , Edited by: Ortiz de Montellano , PR . 3 – 48 . New York : Plenum Press .
  • Houtman , CJ , Van Oostveen , AM , Brouwer , A , Lamoree , MH and Legler , J . 2004 . Identification of estrogenic compounds in fish bile using bioassay-directed fractionation . Environmental Science and Technology , 38 : 6415 – 23 .
  • Kao , LR and Birnbaum , LS . 1986 . Disposition of o-benzyl-p-chlorophenol in male rats . Journal of Toxicology and Environmental Health , 18 : 441 – 58 .
  • Kolpin , DW , Furlong , ET , Meyer , MT , Thurman , EM , Zaugg , SD , Barber , LB and Buxton , HT . 2002 . Pharmaceuticals, hormones, and other wastewater contaminants in U.S. streams, 1999–2000: A national reconnaissance . Environmental Science and Technology , 36 : 1202 – 11 .
  • Kostas , PV and Minor , JC . 2002 . Ipso-substitution by cytochrome P450 with conversion of p-hydroxybenzene derivatives to hydroquinone: Evidence for hydroperoxo-iron as the active oxygen species . Archives of Biochemistry and Biophysics , 397 : 119 – 29 .
  • Lewis , DFV , Ioannides , C and Parke , DV . 1998 . Cytochrome P450 and species differences in xenobiotic metabolism and activation of carcinogen . Environmental Health Perspectives , 106 : 633 – 41 .
  • Lindstrom , A , Buerge , IJ , Poiger , T , Bergquist , PA , Muller , MD and Buser , HR . 2002 . Occurrence and environmental behavior of the bactericide triclosan and its methyl derivative in surface water and in wastewater . Environmental Science and Technology , 36 : 2322 – 9 .
  • Loraine , GA and Pettigrove , ME . 2006 . Seasonal variations in concentration of pharmaceuticals and personal care products in drinking water and reclaimed wastewater in southern California . Environmental Science and Technology , 40 : 687 – 95 .
  • Obach , RS . 1999 . Prediction of human clearance of twenty nine drugs from hepatic microsomal intrinsic clearance data: An examination of in vitro half-life approach and non specific binding to microsomes . Drug Metabolism and Disposition , 27 : 1350 – 9 .
  • Ohe , T , Mashino , T and Hirobe , M . 1996 . Substituent elimination from p-substituted phenols by cytochrome P450 . Drug Metabolism and Disposition , 25 : 116 – 22 .
  • Oros , DR , Jarman , WM , Lowe , T , David , N , Lowe , S and Davis , JA . 2003 . Surveillance for previously unmonitored organic contaminants in the San Francisco Estuary . Marine Pollution Bulletin , 46 : 1102 – 10 .
  • Orvos , DR , Versteeg , DJ , Inauen , J , Capdevielle , M , Rothenstein , A and Cunningham , V . 2002 . Aquatic toxicity of triclosan . Environmental Toxicology and Chemistry , 21 : 1338 – 49 .
  • Reiss , R , Mackay , N , Habig , C and Griffin , J . 2002 . An ecological risk assessment for triclosan in lotic systems following discharge from wastewater treatment plants in the United States . Environmental Toxicology and Chemistry , 21 : 2483 – 92 .
  • Ridley , WP , Sewall , MR and Dietrich , MW . 1986 . Metabolism and disposition of ortho-benzyl-para-chlorophenol in male rats . Journal of Toxicology and Environmental Health , 18 : 267 – 83 .
  • Tassaneeyakul , W , Birkett , DJ , Edwards , JW , Veronese , ME , Tassaneeyakul , W , Tukey , RH and Miners , JO . 1996 . Human cytochrome P450 isoform specificity in the regioselective metabolism of toluene and o-, m- and p-xylene . The Journal of Pharmacology and Experimental Therapeutics , 276 : 101 – 8 .
  • Tracy , TS and Hummel , MA . 2004 . Modeling kinetic data from in vitro drug metabolism enzyme experiments . Drug Metabolism Review , 36 : 231 – 42 .
  • Tulp , MTM , Sundstrom , G , Martron , LBJM and Huntzinger , O . 1979 . Metabolism of chlorodiphenyl ethers and Irgasan® DP300 . Xenobiotica , 9 : 65 – 77 .
  • Werner , AF , Taulli , TA , Michael , PR and Williams , MA . 1983 . Estimation and verification of the environmental fate of o-benzyl-p-chlorophenol . Archives of Environmental Contamination and Toxicology , 12 : 569 – 75 .
  • Yamarik , TA and Andersen , FA . 2004 . Safety assessment of dichlorophene and chlorophene . International Journal of Toxicology , 23 ( Suppl. no. 1 ) : 1 – 27 .
  • Zhao , J-L , Ying , G-G , Wang , L , Yang , J-F , Yang , X-B , Yang , L-H and Li , X . 2009 . Determination of phenolic endocrine disrupting chemicals and acidic pharmaceuticals in surface water of the Pearl Rivers in South China by gas chromatography–negative chemical ionization mass spectrometry . The Science of Total Environment , 407 : 962 – 74 .

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