89
Views
0
CrossRef citations to date
0
Altmetric
Eco/Toxicology

Cytotoxic and proinflammatory response of RAW 264.7 cells to differentially fractionated fungal fragments

&
Pages 1386-1398 | Received 21 Feb 2011, Accepted 13 May 2011, Published online: 15 Jul 2011

References

  • Atalla , MM , Hassanein , NM , El-Beih , AA and Youssef , YA . 2003 . Mycotoxin production in wheat grains by different Aspergilli in relation to different relative humidities and storage periods . Nahrung , 47 : 6 – 10 .
  • Atoui , A , Mitchell , D , Mathieu , F , Magan , N and Lebrihi , A . 2007 . Partitioning of ochratoxin A in mycelium and conidia of Aspergillus carbonarius and the impact on toxin contamination of grapes and wine . Journal of Applied Microbiology , 103 : 961 – 8 .
  • Bae , HK and Pestka , JJ . 2008 . Deoxynivalenol induces p38 interaction with the ribosome in monocytes and macrophages . Toxicological Sciences , 105 : 59 – 66 .
  • Bennett , JW and Klich , M . 2003 . Mycotoxins . Clinical Microbiology Reviews , 16 : 497 – 516 .
  • Bloom , E , Bal , K , Nyman , E , Must , A and Larsson , L . 2007 . Mass spectrometry-based strategy for direct detection and quantification of some mycotoxins produced by Stachybotrys and Aspergillus spp. in indoor environments. . Applied and Environmental Microbiology , 73 : 4211 – 17 .
  • Bondy , GS and Pestka , JJ . 2000 . Immunomodulation by fungal toxins . Journal of Toxicology and Environmental Health, Part B: Critical Reviews , 3 : 109 – 43 .
  • Brasel , TL , Douglas , DR , Wilson , SC and Straus , DC . 2005 . Detection of airborne Stachybotrys chartarum macrocyclic trichothecene mycotoxins on particulates smaller than conidia . Applied and Environmental Microbiology , 71 : 114 – 22 .
  • Brasel , TL , Martin , JM , Carriker , CG , Wilson , SC and Straus , DC . 2005 . Detection of airborne Stachybotrys chartarum macrocyclic trichothecene mycotoxins in the indoor environment . Applied and Environmental Microbiology , 71 : 7376 – 88 .
  • Caivano , M and Cohen , P . 2000 . Role of mitogen-activated protein kinase cascades in mediating lipopolysaccharide-stimulated induction of cyclooxygenase-2 and IL-1 beta in RAW264 macrophages . Journal of Immunology , 164 : 3018 – 25 .
  • Carmichael , J , Degraff , WG , Gazdar , AF , Minna , JD and Mitchell , JB . 1987 . Evaluation of a tetrazolium-based semiautomated colorimetric assay – Assessment of radiosensitivity . Cancer Research , 47 : 943 – 6 .
  • Charpin-Kadouch , C , Maurel , G , Felipo , R , Queralt , J , Ramadour , M , Dumon , H , Garans , M , Botta , A and Charpin , D . 2006 . Mycotoxin identification in moldy dwellings . Journal of Applied Toxicology , 26 : 475 – 9 .
  • Chung , YJ , Jarvis , B and Pestka , J . 2003 . Modulation of lipopolysaccharide-induced proinflammatory cytokine production by satratoxins and other macrocyclic trichothecenes in the murine macrophage . Journal of Toxicology and Environmental Health, Part A: Current Issues , 66 : 379 – 91 .
  • Chung , YJ , Yang , GH , Islam , Z and Pestka , JJ . 2003 . Up-regulation of macrophage inflammatory protein-2 and complement 3A receptor by the trichothecenes deoxynivalenol and satratoxin G . Toxicology , 186 : 51 – 65 .
  • Chung , YJ , Zhou , HR and Pestka , JJ . 2003 . Transcriptional and posttranscriptional roles for p38 mitogen-activated protein kinase in upregulation of TNF-alpha expression by deoxynivalenol (vomitoxin) . Toxicology and Applied Pharmacology , 193 : 188 – 201 .
  • Clark , HA and Snedeker , SM . 2006 . Ochratoxin a: its cancer risk and potential for exposure . Journal of Toxicology and Environmental Health, Part B: Critical Reviews , 9 : 265 – 96 .
  • Cole , RJ and Cox , RH . 1981 . Handbook of toxic fungal metabolites , New York : Academic Press .
  • Dean , TR , Black , JA , Foardeb , K and Mentrez , M . 2008 . Analysis of fungal spore mycotoxin and the relationship between spore surface area and mycotoxin content utilizing a protein translation inhibition assay . The Open Mycology Journal , 2 : 55 – 60 .
  • Dresden-Osborne , C and Noblet , GP . 2002 . Fumonisin B1 affects viability and alters nitric oxide production of a murine macrophage cell line . International Immunopharmacology , 2 : 1087 – 93 .
  • El-Shanawany , AA , Mostafa , ME and Barakat , A . 2005 . Fungal populations and mycotoxins in silage in Assiut and Sohag governorates in Egypt, with a special reference to characteristic Aspergilli toxins . Mycopathologia , 159 : 281 – 9 .
  • Fog Nielsen , K . 2003 . Mycotoxin production by indoor molds . Fungal Genetics and Biology , 39 : 103 – 17 .
  • Gunsch , CK , Cheng , Q , Kinney , KA , Szaniszlo , PJ and Whitman , CP . 2005 . Identification of a homogentisate-1,2-dioxygenase gene in the fungus Exophiala lecanii-corni: Analysis and implications . Applied Microbiology and Biotechnology , 68 : 405 – 11 .
  • Heller , M , Rosner , H , Burkert , B , Moller , U , Hinsching , A , Rohrmann , B , Thierbach , S and Kohler , H . 2002 . [In vitro studies into the influence of ochratoxin A on the production of tumor necrosis factor alpha by the human monocytic cell line THP-1] . Dtsch Tierarztl Wochenschr , 109 : 200 – 5 .
  • Jarvis , BB , Sorenson , WG , Hintikka , EL , Nikulin , M , Zhou , Y , Jiang , J , Wang , S , Hinkley , S , Etzel , RA and Dearborn , D . 1998 . Study of toxin production by isolates of Stachybotrys chartarum and Memnoniella echinata isolated during a study of pulmonary hemosiderosis in infants . Applied and Environmental Microbiology , 64 : 3620 – 5 .
  • Li , M and Pestka , JJ . 2008 . Comparative induction of 28S ribosomal RNA cleavage by ricin and the trichothecenes deoxynivalenol and T-2 toxin in the macrophage . Toxicological Sciences , 105 : 67 – 78 .
  • Miller , JD , Sun , M , Gilyan , A , Roy , J and Rand , TG . 2010 . Inflammation-associated gene transcription and expression in mouse lungs induced by low molecular weight compounds from fungi from the built environment . Chemico-Biological Interactions , 183 : 113 – 24 .
  • Moon , Y and Pestka , JJ . 2002 . Vomitoxin-induced cyclooxygenase-2 gene expression in macrophages mediated by activation of ERK and p38 but not JNK mitogen-activated protein kinases . Toxicological Sciences , 69 : 373 – 82 .
  • Moon , Y and Pestka , JJ . 2003 . Cyclooxygenase-2 mediates interleukin-6 upregulation by vomitoxin (deoxynivalenol) in vitro and in vivo . Toxicology and Applied Pharmacology , 187 : 80 – 88 .
  • Muller , G , Rosner , H , Rohrmann , B , Erler , W , Geschwend , G , Grafe , U Burkert , B . 2003 . Effects of the mycotoxin ochratoxin A and some of its metabolites on the human cell line THP-1 . Toxicology , 184 : 69 – 82 .
  • Murthy , PK , Dennis , VA , Lasater , BL and Philipp , MT . 2000 . Interleukin-10 modulates proinflammatory cytokines in the human monocytic cell line THP-1 stimulated with Borrelia burgdorferi lipoproteins . Infection and Immunity , 68 : 6663 – 9 .
  • Pei , R and Gunsch , CK . 2011 . Inflammatory cytokine gene expression in THP-1 cells exposed to Stachybotrys chartarum and Aspergillus versicolor . Environmental Toxicology , in press (doi/10.1002/tox.20698)
  • Pestka , J and Zhou , HR . 2006 . Toll-like receptor priming sensitizes macrophages to proinflammatory cytokine gene induction by deoxynivalenol and other toxicants . Toxicological Sciences , 92 : 445 – 55 .
  • Pestka , JJ and Smolinski , AT . 2005 . Deoxynivalenol: Toxicology and potential effects on humans . Journal of Toxicology and Environmental Health, Part B: Critical Reviews , 8 : 39 – 69 .
  • Pestka , JJ , Yike , I , Dearborn , DG , Ward , MD and Harkema , JR . 2008 . Stachybotrys chartarum, trichothecene mycotoxins, and damp building-related illness: new insights into a public health enigma . Toxicological Sciences , 104 : 4 – 26 .
  • Rosenbaum , JT , Planck , SR , Huang , XN , Rich , L and Ansel , JC . 1995 . Detection of messenger-RNA for the cytokines, interleukin-1-alpha and interleukin-8, in corneas from patients with pseudophakic bullous keratopathy . Investigative Ophthalmology & Visual Science , 36 : 2151 – 5 .
  • Schoental , R . 1983 . Chronic, including teratogenic and carcinogenic effects of trichothecenes – A short review . Veterinary Research Communications , 7 : 165 – 70 .
  • Stadnyk , AW , Gillan , TL and Anderson , R . 1997 . Respiratory syncytial virus triggers synthesis of IL-6 in BALB/c mouse alveolar macrophages in the absence of virus replication . Cellular Immunology , 176 : 122 – 6 .
  • Strehlau , J , Pavlakis , M , Lipman , M , Shapiro , M , Vasconcellos , L , Harmon , W and Strom , TB . 1997 . Quantitative detection of immune activation transcripts as a diagnostic tool in kidney transplantation . Proceedings of the National Academy of Sciences of the United States of America , 94 : 695 – 700 .
  • Sudakin , D and Fallah , P . 2008 . Toxigenic fungi and mycotoxins in outdoor, recreational environments . Clinical Toxicology , 46 : 738 – 44 .
  • Sudakin , DL . 2003 . Trichothecenes in the environment: Relevance to human health . Toxicology Letters , 143 : 97 – 107 .
  • Ueno , Y . 1985 . The toxicology of mycotoxins . Critical Reviews in Toxicology , 14 : 99 – 132 .
  • Versilovskis , A and De Saeger , S . 2010 . Sterigmatocystin: Occurrence in foodstuffs and analytical methods – An overview . Molecular Nutrition & Food Research , 54 : 136 – 47 .
  • Wong , S , Schwartz , RC and Pestka , JJ . 2001 . Superinduction of TNF-alpha and IL-6 in macrophages by vomitoxin (deoxynivalenol) modulated by mRNA stabilization . Toxicology , 161 : 139 – 49 .
  • Wong , SS , Zhou , HR , Marin-Martinez , ML , Brooks , K and Pestka , JJ . 1998 . Modulation of IL-1beta, IL-6 and TNF-alpha secretion and mRNA expression by the trichothecene vomitoxin in the RAW 264.7 murine macrophage cell line . Food Chem Toxicol , 36 : 409 – 19 .
  • Wong , SS , Zhou , HR and Pestka , JJ . 2002 . Effects of vomitoxin (deoxynivalenol) on the binding of transcription factors AP-1, NF-kappaB, and NF-IL6 in raw 264.7 macrophage cells . Journal of Toxicology and Environmental Health, Part A: Current Issues , 65 : 1161 – 80 .
  • Xia , DY , Sanders , A , Shah , M , Bickerstaff , A and Orosz , C . 2001 . Real-time polymerase chain reaction analysis reveals an evolution of cytokine mRNA production in allograft acceptor mice . Transplantation , 72 : 907 – 14 .
  • Yang , GH , Jarvis , BB , Chung , YJ and Pestka , JJ . 2000 . Apoptosis induction by the satratoxins and other trichothecene mycotoxins: Relationship to ERK, p38 MAPK, and SAPK/JNK activation . Toxicology and Applied Pharmacology , 164 : 149 – 60 .
  • Zhou , HR , Islam , Z and Pestka , JJ . 2005 . Induction of competing apoptotic and survival signaling pathways in the macrophage by the ribotoxic trichothecene deoxynivalenol . Toxicological Sciences , 87 : 113 – 22 .
  • Zhou , HR , Jia , Q and Pestka , JJ . 2005 . Ribotoxic stress response to the trichothecene deoxynivalenol in the macrophage involves the SRC family kinase Hck . Toxicological Sciences , 85 : 916 – 26 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.