858
Views
19
CrossRef citations to date
0
Altmetric
Original Articles

Effect of Induced Charge on Deposition of Uniformly Charged Particles in a Pediatric Oral-Extrathoracic Airway

, , &
Pages 508-514 | Received 09 Nov 2013, Accepted 08 Feb 2014, Published online: 28 Mar 2014

REFERENCES

  • Ali , M. , Mazumder , M. K. and Martonen , T. B. 2009 . Measurements of Electrodynamic Effects on the Deposition of MDI and DPI Aerosols in a Replica Cast of Human Oral – Pharyngeal – Laryngeal Airways . J. Aerosol Med., , 22 : 35 – 44 .
  • Ali , M. , Reddy , R. N. and Mazumder , M. K. 2008 . Electrostatic Charge Effect on Respirable Aerosol Particle Deposition in a Cadaver Based Throat Cast Replica . J. Electrostat., , 66 : 401 – 406 .
  • Ashgriz , N. and Yarin , A. L. 2011 . Handbook of Atomization and Sprays Springer, New York
  • Azhdarzadeh , M. , Olfert , J. S. , Vehring , R. and Finlay , W. H. 2014 . Effect of Electrostatic Charge on Oral-Extrathoracic Deposition for Uniformly Charged Monodisperse Aerosols . J. Aerosol Sci., , 68 : 38 – 45 .
  • Bailey , A. G. , Hashish , A. H. and Williams , T. J. 1998 . Drug Delivery by Inhalation of Charged Particles . J. Electrostat., , 44 : 3 – 10 .
  • Balachandran , W. , Machowski , W. , Gaura , E. and Hudson , C. 1997 . Control of Drug Aerosol in Human Airways using Electrostatic Forces . J. Electrostat., , 40–41 : 579 – 584 .
  • Becquemin , M. , Swift , D. , Bouchikhi , A. , Roy , M. and Teillac , A. 1991 . Particle Deposition and Resistance in the Noses of Adults and Children . Eur. Respir. J., , 4 : 694 – 702 .
  • Below , A. , Bickmann , D. and Breitkreutz , J. 2013 . Assessing the Performance of Two Dry Powder Inhalers in Preschool Children using an Idealized Pediatric Upper Airway Model . Int. J.Pharm., , 444 : 169 – 174 .
  • Bennett , W. D. and Zeman , K. L. 2004 . Effect of body size on breathing pattern and fine-particle deposition in children . J. Appl. Physiol. , 97 : 821 – 826 .
  • Berglund , R. N. and Liu , B. Y. H. 1973 . Generation of Monodisperse Aerosol Standards . Environ. Sci. Technol., , 7 : 147 – 153 .
  • Bickmann , D. , Wachtel , H. , Kroger , R. and Langguth , P. 2008 . Examining Inhler Performance Using a Child's Throat Model, in Respiratory Drug Delivery . : 565 – 570 .
  • Borgström , L. 1999 . In vitro, ex vivo, in vivo Veritas . Allergy , 54 : 88 – 92 .
  • Borgström , L. , Olsson , B. and Thorsson , L. 2006 . Degree of Throat Deposition Can Explain the Variability in Lung Deposition of Inhaled Drugs . J. Aerosol Med., , 19 : 473 – 483 .
  • Bowes , S. M. and Swift , D. L. 1989 . Deposition of Inhaled Particles in the Oral Airway During Oronasal Breathing . Aerosol Sci. Technol., , 11 : 157 – 167 .
  • Brancatisano , T. , Collett , P. W. and Engel , L. A. 1983 . Respiratory Movements of the Vocal Cords . J. Appl. Physiol., , 54 : 1269 – 1276 .
  • Byron , P. R. , Peart , J. and Staniforth , J. N. 1997 . Aerosol Electrostatics I: Properties of Fine Powders Before and After Aerosolization by Dry Powder Inhalers . Pharm. Res., , 14 : 698 – 705 .
  • Cass , L. M. R. , Brown , J. , Pickford , M. , Fayinka , S. , Newman , S. P. Johansson , C. J. 1999 . Pharmacoscintigraphic Evaluation of Lung Deposition of Inhaled Zanamivir in Healthy Volunteers . Clin. Pharmacok., , 36 : 21 – 31 .
  • Chan , T. L. and Lippmann , M. 1980 . Experimental Measurements and Empirical Modelling of the Regional Deposition of Inhaled Particles in Humans . Am. Ind. Hyg. Assoc. J., , 41 : 399 – 409 .
  • DeHaan , W. H. and Finlay , W. H. 2001 . In vitro Monodisperse Aerosol Deposition in a Mouth and Throat with Six Different Inhalation Devices . J. Aerosol Med., , 14 : 361 – 367 .
  • DeHaan , W. H. and Finlay , W. H. 2004 . Predicting Extrathoracic Deposition from Dry Powder Inhalers . J. Aerosol Sci., , 35 : 309 – 331 .
  • Elajnaf , A. , Carter , P. and Rowley , G. 2007 . The Effect of Relative Humidity on Electrostatic Charge Decay of Drugs and Excipient used in Dry Powder Inhaler Formulation . Drug Dev. Ind. Pharm., , 33 : 967 – 974 .
  • Emmett , P. C. , Aitken , R. J. and Hannan , W. J. 1982 . Measurements of the Total and Regional Deposition of Inhaled Particles in the Human Respiratory Tract . J. Aerosol Sci., , 13 : 549 – 560 .
  • Finlay , W. H. 2001 . The Mechanics of Inhaled Pharmaceutical Aerosols: An Introduction . Academic Press, London
  • Foord , N. , Black , A. and Walsh , M. 1978 . Regional Deposition of 2.5–7.5 μm Diameter Inhaled Particles in Healthy Male Non-Smokers . J. Aerosol Sci., , 9 : 343 – 357 .
  • Golshahi , L. and Finlay , W. H. 2012 . An Idealized Child Throat That Mimics Average Pediatric Oropharyngeal Deposition . Aerosol Sci. Technol., , 46 : i – iv .
  • Golshahi , L. , Noga , M. L. and Finlay , W. H. 2012 . Deposition of Inhaled Micrometer-Sized Particles in Oropharyngeal Airway Replicas of Children at Constant Flow Rates . J. Aerosol Sci., , 49 : 21 – 31 .
  • Golshahi , L. , Vehring , R. , Noga , M. L. and Finlay , W. H. 2013 . In vitro Deposition of Micrometer-Sized Particles in the Extrathoracic Airways of Children During Tidal Oral Breathing . J. Aerosol Sci., , 57 : 14 – 21 .
  • Grgic , B. , Finlay , W. H. , Burnell , P. K. P. and Heenan , A. F. 2004 . In vitro Intersubject and Intrasubject Deposition Measurements in Realistic Mouth–Throat Geometries . J. Aerosol Sci., , 35 : 1025 – 1040 .
  • Hall , J. E. 2010 . “ Guyton and Hall Textbook of Medical Physiology ” . Saunders/Elsevier, Philadelphia, PA
  • Hashish , A. H. 1992 . Selective Deposition of Pulsed Aerosols in the Human Lung . J. Aerosol Sci., , 23 : 473 – 476 .
  • Hashish , A. H. , Bailey , A. G. and Williams , T. J. 1994 . Modelling the Effect of Charge on Selective Deposition of Particles in a Diseased Lung using Aerosol Boli . Phys. Med. Biol., , 39 : 2247 – 2262 .
  • Hinds , W. C. 1999 . Aerosol Technology: Properties, Behavior, and Measurement of Airborne Particles . Wiley Interscience, New York
  • Hoe , S. , Traini , D. , Chan , H. K. and Young , P. M. 2009 . Measuring Charge and Mass Distributions in Dry Powder Inhalers using the Electrical Next Generation Impactor (eNGI) . Eur. J. Pharm. Sci., , 38 : 88 – 94 .
  • Kwok , P. C. L. and Chan , H. K. 2009 . Electrostatics of Pharmaceutical Inhalation Aerosols . J. Pharm. Pharm., , 61 : 1587 – 1599 .
  • Kwok , P. C. L. , Glover , W. and Chan , H. K. 2005 . Electrostatic Charge Characteristics of Aerosols Produced from Metered Dose Inhalers . J. Pharm. Sci., , 94 : 2789 – 2799 .
  • Majid , H. , Madl , P. , Hofmann , W. and Alam , K. 2012 . Implementation of Charged Particles Deposition in Stochastic Lung Model and Calculation of Enhanced Deposition . Aerosol Sci. Technol., , 46 : 547 – 554 .
  • Melandri , C. , Tarroni , G. , Prodi , V. , De Zaiacomo , T. , Formignani , M. and Lombardi , C. C. 1983 . Deposition of charged particles in the human airways . J. Aerosol Sci., , 14 : 657 – 669 .
  • Mitchell , J. P. and Nagel , M. 1997 . In Vitro Performance Testing of Three Small Volume-Holding Chambers under Conditions That Correspond with use by Infants and Small Children . J. Aerosol Med., , 10 : 341 – 349 .
  • Moore , A. D. 1973 . “ Electrostatics and Its Applications ” . Wiley, New York
  • Rayleigh , L. 1879 . On the Instability of Jets . Proc. London Math. Soc., , 10 : 3 – 14 .
  • Reischl , G. , John , W. and Devor , W. 1977 . Uniform Electrical Charging of Monodisperse Aerosols . J. Aerosol Sci., , 8 : 55 – 65 .
  • Saini , D. , Gunamgari , J. , Zulaloglu , C. , Sims , R. A. and Mazumder , M. K. 2004 . Effect of Electrostatic Charge and Size Distributions on Respirable Aerosol Deposition in Lung Model . : 948 – 952 . IEEE Industry Applications Conference. 39th IAS Annual Meeting, Seattle
  • Saini , D. , Yurteri , C. U. , Grable , N. , Sims , R. A. and Mazumder , M. K. 2002 . Drug delivery studies on electrostatically charged dry powder inhaler aerosols using a glass bead lung model . : 2451 – 2453 . EEE Industry Applications Conference. 37th IAS Annual Meeting, Pittsburgh, PA
  • Schueepp , K. G. , Devadason , S. G. , Roller , C. , Minocchieri , S. , Moeller , A. Hamacher , J. 2009 . Aerosol Delivery of Nebulised Budesonide in Young Children with Asthma . Respirat. Med., , 103 : 1738 – 1745 .
  • Stahlhofen , W. , Gebhart , J. , Heyder , J. and Scheuch , G. 1983 . New Regional Deposition Data of the Human Respiratory Tract . J. Aerosol Sci., , 14 : 186 – 188 .
  • Stapleton , K. W. , Guentsch , E. , Hoskinson , M. K. and Finlay , W. H. 2000 . On the Suitability of k–ϵ Turbulence Modeling for Aerosol Deposition in the Mouth and Throat: A Comparison with Experiment . J. Aerosol Sci., , 31 : 739 – 749 .
  • Zhou , Y. , Sun , J. and Cheng , Y. S. 2011 . Comparison of Deposition in the USP and Physical Mouth-Throat Models with Solid and Liquid Particles . J. Aerosol Med. Pulm. Drug Deliv., , 24 : 277 – 284 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.