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Original Articles

Chemical characterization of nanoparticles and volatiles present in mainstream hookah smoke

ORCID Icon, ORCID Icon, ORCID Icon, ORCID Icon, ORCID Icon, , ORCID Icon, ORCID Icon & ORCID Icon show all
Pages 1023-1039 | Received 17 Jan 2019, Accepted 20 May 2019, Published online: 24 Jun 2019

References

  • Akl, E. A., S. Gaddam, S. K. Gunukula, R. Honeine, P. A. Jaoude, and J. Irani. 2010. The effects of waterpipe tobacco smoking on health outcomes: A systematic review. Int. J. Epidemiol. 39 (3):834–857. doi:10.1093/ije/dyq002.
  • Akl, E. A., M. Jawad, W. Y. Lam, C. N. Co, R. Obeid, and J. Irani. 2013. Motives, beliefs and attitudes towards waterpipe tobacco smoking: A systematic review. Harm Reduct. J. 10:1–9. doi:10.1186/1477-7517-10-12.
  • Al Rashidi, M., A. Shihadeh, and N. A. Saliba. 2008. Volatile aldehydes in the mainstream smoke of the narghile waterpipe. Food Chem. Toxicol. 46 (11):3546–3549. doi:10.1016/j.fct.2008.09.007.
  • Aljarrah, K., Z. Q. Ababneh, and W. K. Al-Delaimy. 2009. Perceptions of hookah smoking harmfulness: Predictors and characteristics among current hookah users. Tob. Induced Dis. 5 (1):16–22. doi:10.1186/1617-9625-5-16.
  • Aslam, H. M., S. Saleem, S. German, and W. A. Qureshi. 2014. Harmful effects of shisha: Literature review. Int. Arch. Med. 7 (1):16–24. doi:10.1186/1755-7682-7-16.
  • Baasandorj, M., D. B. Millet, L. Hu, D. Mitroo, and B. J. Williams. 2015. Measuring acetic and formic acid by proton-transfer-reaction mass spectrometry: Sensitivity, humidity dependence, and quantifying interferences. Atmos. Meas. Tech. 8 (3):1303–1321. doi:10.5194/amt-8-1303-2015.
  • Baker, R. R., and M. Dixon. 2006. The retention of tobacco smoke constituents in the human respiratory tract. Inhal. Toxicol. 18 (4):255–294. doi:10.1080/08958370500444163.
  • Betzer, O., M. Shilo, R. Opochinsky, E. Barnoy, M. Motiei, E. Okun, G. Yadid, and R. Popovtzer. 2017. The effect of nanoparticle size on the ability to cross the blood-brain barrier: An in vivo study. Nanomedicine-UK 12 (13):1533–1546. doi:10.2217/nnm-2017-0022.
  • Blair, S. L., S. A. Epstein, S. A. Nizkorodov, and N. Staimer. 2015. A real-time fast-flow tube study of VOC and particulate emissions from electronic, potentially reduced-harm, conventional, and reference cigarettes. Aerosol Sci. Tech. 49 (9):816–827. doi:10.1080/02786826.2015.1076156.
  • Breiev, K., K. M. M. Burseg, G. O'Connell, E. Hartungen, S. S. Biel, X. Cahours, S. Colard, T. D. Mark, and P. Sulzer. 2016. An online method for the analysis of volatile organic compounds in electronic cigarette aerosol based on proton transfer reaction mass spectrometry. Rapid Commun. Mass Spectrom. 30 (6):691–697. doi:10.1002/rcm.7487.
  • Brilli, F., B. Gioli, P. Ciccioli, D. Zona, F. Loreto, I. A. Janssens, and R. Ceulemans. 2014. Proton transfer reaction time-of-Flight mass spectrometric (PTR-TOF-MS) determination of volatile organic compounds (VOCs) emitted from a biomass fire developed under stable nocturnal conditions. Atmos. Environ. 97:54–67. doi:10.1016/j.atmosenv.2014.08.007.
  • Brinkman, M. C., H. Kim, S. S. Buehler, A. M. Adetona, S. M. Gordon, and P. I. Clark. 2018. Evidence of compensation among waterpipe smokers using harm reduction components. Tob. Control. 1–9. doi:10.1136/tobaccocontrol-2018-054502.
  • Brinkman, M. C., H. Kim, J. C. Chuang, R. R. Kroeger, D. Deojay, P. I. Clark, and S. M. Gordon. 2015. Comparison of true and smoothed puff profile replication on smoking behavior and mainstream smoke emissions. Chem. Res. Toxicol. 28 (2):182–190. doi:10.1021/tx500318h.
  • Bruns, E. A., J. G. Slowik, I. El Haddad, D. Kilic, F. Klein, J. Dommen, B. Temime-Roussel, N. Marchand, U. Baltensperger, and A. S. H. Prévôt. 2017. Characterization of gas-phase organics using proton transfer reaction time-of-flight mass spectrometry: Fresh and aged residential wood combustion emissions. Atmos. Chem. Phys. 17 (1):705–720. doi:10.5194/acp-17-705-2017.
  • Cavus, U. Y., Z. H. Rehber, O. Ozeke, and E. Ilkay. 2010. Carbon monoxide poisoning associated with narghile use. Emerg. Med. J. 27(5):406–406. doi:10.1136/emj.2009.077214.
  • Chaouachi, K. 2009. Hookah (shisha, narghile) smoking and environmental tobacco smoke (ETS). A critical review of the relevant literature and the public health consequences. IJERPH 6 (2):798–843. doi:10.3390/ijerph6020798.
  • Chow, J. C., and J. G. Watson. 2007. Overview of ultrafine particles and human health. WIT Trans. Ecol. Environ. 99:619–632. doi:10.2495/Rav060601.
  • Cobb, C., K. D. Ward, W. Maziak, A. L. Shihadeh, and T. Eissenberg. 2010. Waterpipe tobacco smoking: An emerging health crisis in the United States. Am. J. Health Behav. 34 (3):275–285. doi:10.5993/Ajhb.34.3.3.
  • Corma, A., G. Huber, L. Sauvanaud, and P. Oconnor. 2008. Biomass to chemicals: Catalytic conversion of glycerol/water mixtures into acrolein, reaction network. J. Catal. 257 (1):163–171. doi:10.1016/j.jcat.2008.04.016.
  • Dass, C. 1994. Gas-phase fragmentation reactions of protonated glycerol and its oligomers - Metastable and collision-induced dissociation reactions, associated deuterium-isotope effects and the structure of [C3H5O]+, [C2H5O]+, [C2H4O]+. and [C2H3O]+ ions. Org. Mass Spectrom. 29 (9):475–482. doi:10.1002/oms.1210290906.
  • de Gouw, J., and C. Warneke. 2007. Measurements of volatile organic compounds in the earths atmosphere using proton-transfer-reaction mass spectrometry. Mass Spectrom. Rev. 26(2):223–257. doi:10.1002/mas.20119.
  • Eichorn, L., D. Michaelis, M. Kemmerer, B. Juttner, and K. Tetzlaff. 2018. Carbon monoxide poisoning from waterpipe smoking: A retrospective cohort study. Clin. Toxicol. 56:264–272. doi:10.1080/15563650.2017.1375115.
  • El-Zaatari, Z. M., H. A. Chami, and G. S. Zaatari. 2015. Health effects associated with waterpipe smoking. Tob. Control 24:31–43. doi:10.1136/tobaccocontrol-2014-051908.
  • Eldridge, A., T. R. Betson, M. V. Gama, and K. McAdam. 2015. Variation in tobacco and mainstream smoke toxicant yields from selected commercial cigarette products. Regul. Toxicol. Pharm. 71 (3):409–427. doi:10.1016/j.yrtph.2015.01.006.
  • Fakhreddine, H. M. B., A. N. Kanj, and N. A. Kanj. 2014. The growing epidemic of water pipe smoking: Health effects and future needs. Resp. Med. 108:1241–1253. doi:10.1016/j.rmed.2014.07.014.
  • Feng, Z. H., W. W. Hu, Y. Hu, and M. S. Tang. 2006. Acrolein is a major cigarette-related lung cancer agent: Preferential binding at p53 mutational hotspots and inhibition of DNA repair. Proc. Natl. Acad. Sci. USA. 103 (42):15404–15409. doi:10.1073/pnas.0607031103.
  • Fitzpatrick, E. M., A. B. Ross, J. Bates, G. Andrews, J. M. Jones, H. Phylaktou, M. Pourkashanian, and A. Williams. 2007. Emission of oxygenated species from the combustion of pine wood and its relation to soot formation. Process Saf. Environ. 85 (5):430–440. doi:10.1205/psep07020.
  • Gordon, S. M., M. C. Brinkman, R. Q. Meng, G. M. Anderson, J. C. Chuang, R. R. Kroeger, I. L. Reyes, and P. I. Clark. 2011. Effect of cigarette menthol content on mainstream smoke emissions. Chem. Res. Toxicol. 24 (10):1744–1753. doi:10.1021/tx200285s.
  • Greaves, J., and J. Roboz. 2014. Mass spectromtry for the novice. Boca Raton, FL: CRC Press.
  • Grekin, E. R., and D. Ayna. 2008. Argileh use among college students in the United States: An emerging trend. J. Stud. Alcohol Drugs 69 (3):472–475. doi:10.15288/jsad.2008.69.472.
  • Grekin, E. R., and D. Ayna. 2012. Waterpipe smoking among college students in the United States: A review of the literature. J. Am. Coll. Health 60 (3):244–249. doi:10.1080/07448481.2011.589419.
  • Hammal, F., A. Chappell, T. C. Wild, W. Kindzierski, A. Shihadeh, A. Vanderhoek, C. K. Huynh, G. Plateel, and B. A. Finegan. 2015. Herbal' but potentially hazardous: An analysis of the constituents and smoke emissions of tobacco-free waterpipe products and the air quality in the cafes where they are served. Tob. Control 24 (3):290–297. doi:10.1136/tobaccocontrol-2013-051169.
  • Haase, K. B., W. C. Keene, A. A. P. Pszenny, H. R. Mayne, R. W. Talbot, and B. C. Sive. 2012. Calibration and intercomparison of acetic acid measurements using proton-transfer-reaction mass spectrometry (PTR-MS). Atmos. Meas. Tech. 5:2739–2750. doi:10.5194/amt-5-2739-2012.
  • Hemings, E. B., C. Cavallotti, A. Cuoci, T. Faravelli, and E. Ranzi. 2012. A detailed kinetic study of pyrolysis and oxidation of glycerol (propane-1,2,3-triol). Combust. Sci. Technol. 184 (7–8):1164–1178. doi:10.1080/00102202.2012.664006.
  • Hinds, W. C. 1999. Aerosol technology: Properties, behavior, and measurement of airborne particles. 2nd ed. New York: John Wiley & Sons.
  • Hogan, C. J., E. M. Kettleson, M. H. Lee, B. Ramaswami, L. T. Angenent, and P. Biswas. 2005. Sampling methodologies and dosage assessment techniques for submicrometre and ultrafine virus aerosol particles. J. Appl. Microbiol. 99 (6):1422–1434. doi:10.1111/j.1365-2672.2005.02720.x.
  • IARC. 1999. IARC monographs on the evaluation of carcinogenic risks to Humans - Re-Evaluation of some organic chemicals, hydrazine and hydrogen peroxide. Lyon, France: IARC Press.
  • Ingebrethsen, B. J., S. K. Cole, and S. L. Alderman. 2012. Electronic cigarette aerosol particle size distribution measurements. Inhal. Toxicol. 24 (14):976–984. doi:10.3109/08958378.2012.744781.
  • Jamal, A., A. Gentzke, S. S. Hu, K. A. Cullen, B. J. Apelberg, D. M. Homa, and B. A. King. 2017. Tobacco use among Middle and high school students - United States, 2011-2016. MMWR Morb. Mortal. Wkly Rep. 66 (23):597–603. doi:10.15585/mmwr.mm6623a1.
  • Jawad, M., T. Eissenberg, R. Salman, E. Soule, K. H. Alzoubi, O. F Khabour, N. Karaoghlanian, R. Baalbaki, R. El Hage, N. Saliba, and A. Shihadeh. 2019. Toxicant inhalation among singleton waterpipe tobacco users in natural settings. Tob. Control 28 (2):181–188. doi:10.1136/tobaccocontrol-2017-054230.
  • Jensen, R. P., R. M. Strongin, and D. H. Peyton. 2017. Solvent chemistry in the electronic cigarette reaction vessel. Sci Rep. 7:42549–42559. doi:10.1038/srep42549.
  • John, E., S. Coburn, C. Liu, J. McAughey, D. Mariner, K. G. McAdam, Z. Sebestyen, I. Bakos, and S. Dobe. 2018. Effect of temperature and humidity on the gas-particle partitioning of nicotine in mainstream cigarette smoke: A diffusion denuder study. J. Aerosol Sci. 117:100–117. doi:10.1016/j.jaerosci.2017.12.015.
  • Jordan, A., S. Haidacher, G. Hanel, E. Hartungen, L. Mark, H. Seehauser, R. Schottkowsky, P. Sulzer, and T. D. Mark. 2009. A high resolution and high sensitivity proton-transfer-reaction time-of-flight mass spectrometer (PTR-TOF-MS). Int. J. Mass Spectrom. 286 (2–3):122–128. doi:10.1016/j.ijms.2009.07.005.
  • Karl, T. G., T. J. Christian, R. J. Yokelson, P. Artaxo, W. M. Hao, and A. Guenther. 2007. The tropical Forest and fire emissions experiment: Method evaluation of volatile organic compound emissions measured by PTR-MS, FTIR, and GC from tropical biomass burning. Atmos. Chem. Phys. 7 (22):5883–5897. doi:10.5194/acp-7-5883-2007.
  • Katryniok, B., S. Paul, V. Belliere-Baca, P. Rey, and F. Dumeignil. 2010. Glycerol dehydration to acrolein in the context of new uses of glycerol. Green Chem. 12 (12):2079–2098. doi:10.1039/c0gc00307g.
  • Katurji, M., N. Daher, H. Sheheitli, R. Saleh, and A. Shihadeh. 2010. Direct measurement of toxicants inhaled by water pipe users in the natural environment using a real-time in situ sampling technique. Inhal. Toxicol. 22 (13):1101–1109. doi:10.3109/08958378.2010.524265.
  • Kim, H., M. C. Brinkman, E. Sharma, S. M. Gordon, and P. I. Clark. 2016. Variability in puff topography and exhaled CO in waterpipe tobacco smoking. Tob. Regul. Sci. 2 (4):301–308. doi:10.18001/TRS.2.4.2.
  • Kim, K. H., E. Kabir, and S. A. Jahan. 2016. Waterpipe tobacco smoking and its human health impacts. J. Hazard. Mater. 317:229–236. doi:10.1016/j.jhazmat.2016.05.075.
  • La Fauci, G., G. Weiser, I. P. Steiner, and I. Shavit. 2012. Carbon monoxide poisoning in narghile (waterpipe) tobacco smokers. Can. J. Emerg. Med. 14:57–59. doi:10.2310/8000.2011.110431.
  • Laskin, A., J. S. Smith, and J. Laskin. 2009. Molecular characterization of nitrogen-containing organic compounds in biomass burning aerosols using high-resolution mass spectrometry. Environ. Sci. Technol. 43 (10):3764–3771. doi:10.1021/es803456n.
  • Lawler, M. J., M. P. Rissanen, M. Ehn, R. L. Mauldin, N. Sarnela, M. Sipila, and J. N. Smith. 2018. Evidence for diverse biogeochemical drivers of boreal Forest new particle formation. Geophys. Res. Lett. 45 (4):2038–2046. doi:10.1002/2017gl076394.
  • Lim, B. L., G. H. Lim, and E. Seow. 2009. Case of carbon monoxide poisoning after smoking shisha. Int. J. Emerg. Med. 2 (2):121–122. doi:10.1007/s12245-009-0097-8.
  • Martinasek, M. P., R. J. McDermott, and L. Martini. 2011. Waterpipe (hookah) tobacco smoking among youth. Curr. Prob. Pediatr. Adolesc. Care. 41:34–57. doi:10.1016/j.cppeds.2010.10.001.
  • Martinuzzi, I., Y. Azizi, J. F. Devaux, S. Tretjak, O. Zahraa, and J. P. Leclerc. 2014. Reaction mechanism for glycerol dehydration in the gas phase over a solid acid catalyst determined with on-line gas chromatography. Chem. Eng. Sci. 116:118–127. doi:10.1016/j.ces.2014.04.030.
  • Maziak, W. 2011. The global epidemic of waterpipe smoking. Addict. Behav. 36 (1–2):1–5. doi:10.1016/j.addbeh.2010.08.030.
  • Maziak, W., S. Rastam, I. Ibrahim, K. D. Ward, A. Shihadeh, and T. Eissenberg. 2009. CO exposure, puff topography, and subjective effects in waterpipe tobacco smokers. Nicotine Tob. Res. 11 (7):806–811. doi:10.1093/ntr/ntp066.
  • Mikoviny, T., L. Kaser, and A. Wisthaler. 2010. Development and characterization of a high-temperature proton-transfer-reaction mass spectrometer (HT-PTR-MS). Atmos. Meas. Tech. 3 (3):537–544. doi:10.5194/amt-3-537-2010.
  • Moldoveannu, S., W. I. Coleman, and J. Wilkins. 2007. Determination of carbonyl compounds in exhaled cigarette smoke. Contrib. Tob. Res. 22:346–357. doi:10.2478/cttr-2013-0841.
  • Monn, C., P. Kindler, A. Meile, and O. Brandli. 2007. Ultrafine particle emissions from waterpipes. Tob. Control 16 (6):390–393. doi:10.1136/tc.2007.021097.
  • Monzer, B., E. Sepetdjian, N. Saliba, and A. Shihadeh. 2008. Charcoal emissions as a source of CO and carcinogenic PAH in mainstream narghile waterpipe smoke. Food Chem. Toxicol. 46 (9):2991–2995. doi:10.1016/j.fct.2008.05.031.
  • Muller, M., B. E. Anderson, A. J. Beyersdorf, J. H. Crawford, G. S. Diskin, P. Eichler, A. Fried, F. N. Keutsch, T. Mikoviny, K. L. Thornhill, et al. 2016. In situ measurements and modeling of reactive trace gases in a small biomass burning plume. Atmos. Chem. Phys. 16:3813–3824. doi:10.5194/acp-16-3813-2016.
  • Nimlos, M. R., S. J. Blanksby, X. H. Qian, M. E. Himmel, and D. K. Johnson. 2006. Mechanisms of glycerol dehydration. J. Phys. Chem. A 110 (18):6145–6156. doi:10.1021/jp060597q.
  • Oberdorster, G., Z. Sharp, V. Atudorei, A. Elder, R. Gelein, W. Kreyling, and C. Cox. 2004. Translocation of inhaled ultrafine particles to the brain. Inhal. Toxicol. 16:437–445. doi:10.1080/08958370490439597.
  • Oladhosseini, S., and G. Karimi. 2016. Mathematical modeling of transport phenomena during waterpipe smoking-a parametric study. Int. J. Multiphase Flow 85:314–325. doi:10.1016/j.ijmultiphaseflow.2016.06.022.
  • Pagonis, D., J. E. Krechmer, J. de Gouw, J. L. Jimenez, and P. J. Ziemann. 2017. Effect of gas-wall partitioning in teflon tubing and instrumentation on time-resolved measurements of gas-phase organic compounds. Atmos. Meas. Tech. 10 (12):4687–4696. doi:10.5194/amt-10-4687-2017.
  • Pankow, J. F. 2001. A consideration of the role of gas/particle partitioning in the deposition of nicotine and other tobacco smoke compounds in the respiratory tract. Chem. Res. Toxicol. 14 (11):1465–1481. doi:10.1021/tx0100901.
  • Pankow, J. F., A. D. Tavakoli, W. T. Luo, and L. M. Isabelle. 2003. Percent free base nicotine in the tobacco smoke particulate matter of selected commercial and reference cigarettes. Chem. Res. Toxicol. 16 (8):1014–1018. doi:10.1021/tx0340596.
  • Primack, B. A., J. Sidani, A. A. Agarwal, W. G. Shadel, E. C. Donny, and T. E. Eissenberg. 2008. Prevalence of and associations with waterpipe tobacco smoking among US university students. Ann. Behav. Med. 36 (1):81–86. doi:10.1007/s12160-008-9047-6.
  • Rainey, C. L., J. R. Shifflett, J. V. Goodpaster, and D. Z. Bezabeh. 2013. Quantitative analysis of humectants in tobacco products using gas chromatography (GC) with simultaneous mass spectrometry (MSD) and flame ionization detection (FID). Contrib. Tob. Res. 25:576–585. doi:10.2478/cttr-2013-0934.
  • Retzky, S. 2017. Carbon monoxide poisoning from hookah smoking: An emerging public health problem. J. Med. Toxicol. 13 (2):193–194. doi:10.1007/s13181-017-0617-5.
  • Rezk-Hanna, M., and N. L. Benowitz. 2018. Cardiovascular effects of hookah smoking: Potential implications forcardiovascular risk. Nicotine Tob. Res. 0:1–11. doi:10.1093/ntr/nty065.
  • Roemer, E., H. Schramke, H. Weiler, A. Buettner, S. Kausche, S. Weber, A. Berges, M. Stueber, M. Muench, E. Trelles-Sticken, et al. 2012. Mainstream smoke chemistry and in vitro and in vivo toxicity of the reference cigarettes 3R4F and 3R4F. Beitr. Tabakforsch. Int. 25:316–335. doi:10.2478/cttr-2013-0912.
  • Rogers, T. M., E. R. Grimsrud, S. C. Herndon, J. T. Jayne, C. E. Kolb, E. Allwine, H. Westberg, B. K. Lamb, M. Zavala, L. T. Molina, et al. 2006. On-road measurements of volatile organic compounds in the Mexico City metropolitan area using proton transfer reaction mass spectrometry. Int. J. Mass Spectrom. 252:26–37. doi:10.1016/j.ijms.2006.01.027.
  • Saleh, R., and A. Shihadeh. 2008. Elevated toxicant yields with narghile waterpipes smoked using a plastic hose. Food Chem. Toxicol. 46 (5):1461–1466. doi:10.1016/j.fct.2007.12.007.
  • Salloum, R. G., W. Maziak, D. Hammond, R. Nakkash, F. Islam, X. Cheng, and J. F. Thrasher. 2015. Eliciting preferences for waterpipe tobacco smoking using a discrete choice experiment: Implications for product regulation. BMJ Open 5:1–7. doi: 10.1136/bmjopen-2015-009497.
  • Sampson, M. M., D. M. Chambers, D. Y. Pazo, F. Moliere, B. C. Blount, and C. H. Watson. 2014. Simultaneous analysis of 22 volatile organic compounds in cigarette smoke using gas sampling bags for high-throughput solid-phase microextraction. Anal. Chem. 86 (14):7088–7095. doi:10.1021/ac5015518.
  • Sander, R. 2015. Compilation of Henry's law constants (version 4.0) for water as solvent. Atmos. Chem. Phys. 15:4399–4981. doi:10.5194/acp-15-4399-2015.
  • Schroder, D. 2008. Gaseous rust: Thermochemistry of neutral and ionic iron oxides and hydroxides in the gas phase. J. Phys. Chem. A. 112:13215–13224. doi:10.1021/jp8030804
  • Schubert, J., A. Luch, and T. G. Schulz. 2013. Waterpipe smoking: Analysis of the aroma profile of flavored waterpipe tobaccos. Talanta. 115:665–674. doi:10.1016/j.talanta.2013.06.022.
  • Schubert, J., J. Bewersdorff, A. Luch, and T. G. Schulz. 2012a. Waterpipe smoke: A considerable source of human exposure against furanic compounds. Anal. Chim. Acta. 709:105–112. doi:10.1016/j.aca.2011.10.012.
  • Schubert, J., J. Hahn, G. Dettbarn, A. Seidel, A. Luch, and T. G. Schulz. 2011a. Mainstream smoke of the waterpipe: Does this environmental matrix reveal as significant source of toxic compounds? Toxicol. Lett. 205 (3):279–284. doi:10.1016/j.toxlet.2011.06.017.
  • Schubert, J., V. Heinke, J. Bewersdorff, A. Luch, and T. G. Schulz. 2012b. Waterpipe smoking: The role of humectants in the release of toxic carbonyls. Arch. Toxicol. 86 (8):1309–1316. doi:10.1007/s00204-012-0884-5.
  • Schubert, J., O. Kappenstein, A. Luch, and T. G. Schulz. 2011b. Analysis of primary aromatic amines in the mainstream waterpipe smoke using liquid chromatography-electrospray ionization tandem mass spectrometry. J. Chromatogr. A. 1218 (33):5628–5637. doi:10.1016/j.chroma.2011.06.072.
  • Schubert, J., F. D. Muller, R. Schmidt, A. Luch, and T. G. Schulz. 2015. Waterpipe smoke: Source of toxic and carcinogenic VOCs, phenols and heavy metals? Arch. Toxicol. 89 (11):2129–2139. doi:10.1007/s00204-014-1372-x.
  • Sepetdjian, E., R. A. Halim, R. Salman, E. Jaroudi, A. Shihadeh, and N. A. Saliba. 2013. Phenolic compounds in particles of mainstream waterpipe smoke. Nicotine Tob. Res. 15 (6):1107–1112. doi:10.1093/ntr/nts255.
  • Sepetdjian, E., A. Shihadeh, and N. A. Saliba. 2008. Measurement of 16 polycyclic aromatic hydrocarbons in narghile waterpipe tobacco smoke. Food Chem. Toxicol. 46 (5):1582–1590. doi:10.1016/j.fct.2007.12.028.
  • Shihadeh, A. 2003. Investigation of mainstream smoke aerosol of the argileh water pipe. Food Chem. Toxicol. 41 (1):143–152. doi: Pii S0278-6915(02)00220-X
  • Shihadeh, A., S. Azar, C. Antonios, and A. Haddad. 2004. Towards a topographical model of narghile water-pipe cafe smoking: A pilot study in a high socioeconomic status neighborhood of Beirut, Lebanon. Pharmacol. Biochem. Behav. 79 (1):75–82. doi:10.1016/j.pbb.2004.06.005.
  • Shihadeh, A., T. Eissenberg, M. Rammah, R. Salman, E. Jaroudi, and M. El-Sabban. 2014. Comparison of tobacco-containing and tobacco-free waterpipe products: Effects on human alveolar cells. Nicotine Tob. Res. 16 (4):496–499. doi:10.1093/ntr/ntt193.
  • Shihadeh, A., and R. Saleh. 2005. Polycyclic aromatic hydrocarbons, carbon monoxide, "tar", and nicotine in the mainstream smoke aerosol of the narghile water pipe. Food Chem. Toxicol. 43 (5):655–661. doi:10.1016/j.fct.2004.12.013.
  • Shihadeh, A., R. Salman, E. Jaroudi, N. Saliba, E. Sepetdjian, M. D. Blank, C. O. Cobb, and T. Eissenberg. 2012. Does switching to a tobacco-free waterpipe product reduce toxicant intake? A crossover study comparing CO, NO, PAH, volatile aldehydes, "tar" and nicotine yields. Food Chem. Toxicol. 50 (5):1494–1498. doi:10.1016/j.fct.2012.02.041.
  • Shihadeh, A., J. Schubert, J. Klaiany, M. E. Sabban, A. Luch, and N. A. Saliba. 2015. Toxicant content, physical properties and biological activity of waterpipe tobacco smoke and its tobacco-free alternatives. Tob. Control 24:22–30. doi:10.1136/tobaccocontrol-2014-051907.
  • Smith, J. N., K. F. Moore, P. H. McMurry, and F. L. Eisele. 2004. Atmospheric measurements of Sub-20 nm diameter particle chemical composition by thermal desorption chemical ionization mass spectrometry. Aerosol Sci. Tech. 38 (2):100–110. doi:10.1080/02786820490249036.
  • Smith, J. R., S. D. Edland, T. E. Novotny, C. R. Hofstetter, M. M. White, S. P. Lindsay, and W. K. Al-Delaimy. 2011. Increasing hookah use in California. Am. J. Public Health 101 (10):1876–1879. doi:10.2105/Ajph.2011.300196.
  • Sovova, K., K. Dryahina, and P. Spanel. 2011. Selected ion flow tube (SIFT) studies of the reactions of H3O+, NO+ and O2+• with six volatile phytogenic esters. Int. J. Mass Spectrom. 300:31–38. doi:10.1016/j.ijms.2010.11.021.
  • Spanel, P., and D. Smith. 1997. SIFT studies of the reactions of H3O+, NO+ and O2+ with a series of alcohols. Int. J. Mass Spectrom. 167:375–388. doi:10.1016/S0168-1176(97)00085-2.
  • Spanne, M., P. Grzybowski, and M. Bohgard. 1999. Collection efficiency for submicron particles of a commonly used impinger. Am. Ind. Hyg. Assoc. J. 60 (4):540–544. doi:10.1202/0002-8894(1999)060 < 0540:CEFSPO>2.0.CO;2.
  • Stockwell, C. E., P. R. Veres, J. Williams, and R. J. Yokelson. 2015. Characterization of biomass burning emissions from cooking fires, peat, crop residue, and other fuels with high-resolution proton-transfer-reaction time-of-flight mass spectrometry. Atmos. Chem. Phys. 15 (2):845–865. doi:10.5194/acp-15-845-2015.
  • Sutfin, E. L., E. Y. Song, B. A. Reboussin, and M. Wolfson. 2014. What are young adults smoking in their hookahs? A latent class analysis of substances smoked. Addict. Behav. 39 (7):1191–1196. doi:10.1016/j.addbeh.2014.03.020.
  • Veen, M., 2016. Carbon monoxide poisoning caused by waterpipe smoking: A case series. J. Emerg. Med. 51 (3):E41–E44. doi:10.1016/j.jemermed.2016.05.046.
  • Warneke, C., J. M. Roberts, P. Veres, J. Gilman, W. C. Kuster, I. Burling, R. J. Yokelson, and J. de Gouw. 2011. VOC identification and inter-comparison from laboratory biomass burning using PTR-MS and PIT-MS. Int. J. Mass Spectrom. 303 (1):6–14. doi:10.1016/j.ijms.2010.12.002.
  • Wei, Z. C., R. C. Rosario, and L. D. Montoya. 2010. Collection efficiency of a midget impinger for nanoparticles in the range of 3-100 nm. Atmos. Environ. 44 (6):872–876. doi:10.1016/j.atmosenv.2009.11.037.
  • World Health Organization 2015. Advisory note - Waterpipe tobacco smoking: Health effects, research needs and recommended actions for regulators. Geneva, Switzerland: WHO document Production services.
  • Yuan, B., A. R. Koss, C. Warneke, M. Coggon, K. Sekimoto, and J. A. de Gouw. 2017. Proton-transfer-reaction mass spectrometry: Applications in atmospheric sciences. Chem. Rev. 117 (21):13187–13229. doi:10.1021/acs.chemrev.7b00325.