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Original Articles

Substitution Pharmacotherapies for Opioid Addiction: From Methadone to LAAM and Buprenorphine

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Pages 119-128 | Published online: 23 Jan 2012

REFERENCES

  • Anglin , M. D. , Speckart , G. R. , Booth , M. W. and Ryan , T. M. 1989 . Consequences and costs of shutting off methadone . Addictive Behaviors , 14 : 307 – 26 .
  • Ball , J. C. , Lange , W. R. , Myers , C. P. and Friedman , S. R. 1988 . Reducing the risk of AIDS through methadone maintenance treatment . Journal of Health and Social Behavior , 29 : 214 – 26 .
  • Ball , J. C. and Ross , A. 1993 . The Effectiveness of Methadone Maintenance Treatment: Patients, Programs, Services and Outcome. New York : Springer-Verlag. .
  • Bickel , W. K. , Stitzer , M. L. , Bigelow , G. E. , Liebson , I. A. , Jasinski , D. R. and Johnson , R. E. 1988 . Buprenorphine: Dose-related blockade of opioid challenge effects in opioid dependent humans . Journal of Pharmacology and Experimental Therapeutics , 247 ( 1 ) : 47 – 53 .
  • Blaine , J. D. and Renault , P. F. 1978 . Clinical use of LAAM . Annals of the New York Academy of Sciences , 311 : 214 – 31 .
  • Blaine , J. D. and Renault , P. F. , eds. 1976 . Rx: 3x/week LAAM Alternative to Methadone. Washington , D.C. : U.S. GPO. . National Institute on Drug Abuse Research Monograph 8. DHEW Pub. No. (ADM)76–347
  • Chen , K. K. 1948 . Pharmacology of methadone and related compounds . Annals of the New York academy of Sciences , 51 : 83 – 97 .
  • Cooper , J. R. Methadone treatment and acquired immunodeficiency syndrome . Journal of the American Medical Association , 262 ( 12 ) 1664 – 68 .
  • Cowan , A. , Lewis , J. W. and MacFarlane , I. R. 1977 . Agonist and Antagonist properties of buprenorphine, a new antinociceptive agent . British Journal of Pharmacology , 60 ( 4 ) : 537 – 45 .
  • David , N. A. , Semler , H. J. and Burgner , P. R. 1956 . Control of chronic pain by D-ľ-alpha-acetylmethadol . Journal of the american Medical association , 161 ( 7 ) : 599 – 603 .
  • Des Jarlais , D. C. , Friedman , S. R. and Hopkins , W. 1985 . Risk reduction for acquired immunodeficiency syndrome among intravenous drug users . Annals of Internal Medicine , 103 : 755 – 59 .
  • Dole , V. P. 1989 . Methadone treatment and the acquired immunodeficiency syndrome epidemic . Journal of the american Medical association , 262 ( 12 ) : 1681 – 82 .
  • Dole , V. P. , Nyswander , M. E. and Kreek , M. J. 1966 . Narcotic Blockade . Archives of Internal Medicine , 118 : 304 – 09 .
  • Dole , V. P. , Robinson , J. W. , Orraga , J. , Towns , E. , Searcy , P. and Caine , E. 1969 . Methadone treatment of randomly selected criminal addicts . New England Journal of Medicine , 280 ( 25 ) : 1372 – 75 .
  • Drucker , E. 1986 . AIDS and addiction in New York City . American Jou null of Drug and alcohol abuse , 12 : 165 – 81 .
  • Food and Drug administration . 1993 . Levo-alpha-acetyl-methadol (LAAM) in maintenance: Revision of conditions for use in the treatment of narcotic addiction . Federal Register , 58 ( 137 ) : 38704 – 11 .
  • Fraser , H. F. and Isbell , H. 1952 . actions and addiction liabilities of alpha-acetylmethadols in man . Journal of Pharmacology and Experimental Therapeutics , 105 ( 4 ) : 458 – 62 .
  • Freedman , R. R. and Czertko , G. 1981 . acomparison of thrice weekly LAAM and daily methadone in employed heroin addicts . Drug and Alcohol Dependence , 8 : 215 – 22 .
  • Fudala , P. J. , Jaffe , J. H. , Dax , E. M. and Johnson , R. E. 1990 . Use of buprenorphine in the treatment of opioid addiction. II. Physiologic and behavioral effects of daily and alternate-day administration and abrupt withdrawal . Clinical Pharmacology and Therapeutics , 47 ( 4 ) : 525 – 34 .
  • Fudala , P. J. , Vocci , F. , Montgomery , A. and Collins , J. 1993 . Unpublished, LAAM New Drug application submission
  • Fullerton , T. , Timm , E. G. , Kolski , G. B. and Bertino , J. S. 1991 . Prolonged nausea and vomiting associated with buprenorphine . Pharmacotherapy , 11 ( 1 ) : 90 – 93 .
  • Gerstein , D. R. and Harwood , H. J. , eds. 1990 . Treating Drug abuse Problems, Volume I. Washington , D.C : National academy Press. .
  • Godshaw , G. , Koppel , R. and Pancoast , R. 1987 . anti-Drug LAW Enforcement Efforts and Their Impact. Washington , D.C. : U.S. Custom Services, Department of the Treasury. .
  • Goldstein , A. 1976 . “ Clinical experience with LAAM. ” . In Rx: 3x/week LAAM. Alternative to Methadone. , NIDA Research Monograph 8. Rockville Edited by: Blaine , J. D. and Renault , P. F. Maryland : National Institute on Drug abuse. .
  • Goldstein , A. and Judson , B. 1976 . “ Can the community be protected against the hazards of take-home methadone?. ” . In Rx: 3x/week LAAM. Alternative to Methadone. , NIDA Research Monograph 8 Edited by: Blaine , J. D. and Renault , P. F. Rockville , Maryland : National Institute on Drug abuse. .
  • Gröbladh , L. , Ohlund , J. S. and Gunne , J. M. 1990 . Mortality in heroin addiction: Impact of methadone treatment . Acta Psychiatrica Scandinavica , 82 : 223 – 27 .
  • Hough , G. , Washton , A. M. and Resnick , R. B. 1983 . “ Addressing the diversion of take-home methadone: LAAM as the sole treatment choice for patients seeking maintenance therapy. ” . In Problems of Drug Dependence. , NIDA Research Monograph 43 Edited by: Harris , L. S. Washington , D.C. : U.S. GPO. .
  • Hubbard , R. L. and French , M. T. 1991 . “ New perspectives on the benefit-cost and cost-effectiveness of drug abuse treatment. ” . In Economic Costs. Cost-effectiveness. Financing and Community-based Drug Treatment. , NIDA Research Monograph 113 Edited by: Cartwright , W. S. and Kaple , J. M. Rockville , Maryland : National Institute on Drug Abuse. .
  • Hubbard , R. L. and Marsden , M. E. 1986 . “ Relapse to use of heroin, cocaine and other drugs in the first year after treatment. ” . In Relapse and Recovery in Drug Abuse. , NIDA Research Monograph 72 Edited by: Tims , F. M. and Leukfeld , C. G. Washington , D.C. : U.S. GPO. . DHHS Pub. No. (ADM)89–151963
  • Hubbard , R. L. , Marsden , M. E. , Rachal , J. V. , Harwood , H. J. , Cavanaugh , E. R. and Ginzburg , H. M. 1989 . Drug Abuse Treatment: A National Study of Effectiveness. Chapel Hill : University of North Carolina Press. .
  • Hunt , D. E. , Lipton , D. S. , Goldsmith , D. S. , Strug , D. L. and Spunt , B. 1986 . “It takes your heart”: The image of methadone maintenance in the addict world and its effect on recruitment into treatment . International Journal of the addictions , 20 : 1751 – 71 .
  • Jaffe , J. H. and Senay , E. C. 1971 . Methadone and L-methadyl acetate: Use in management of narcotic addicts . Journal of the American Medical Association , 216 : 1303 – 05 .
  • Jaffe , J. H. , Senay , E. C. , Schuster , C. R. , Renault , P. R. , Smith , B. and DiMenza , S. 1972 . Methadyl acetate vs. methadone: double-blind study in heroin users . Journal of the american Medical Association , 222 : 437 – 42 .
  • Jasinski , D. R. , Pevnick , J. S. and Griffith , J. D. 1978 . Human pharmacology and abuse potential of the analgesic buprenorphine . Archives of General Psvchiatry , 35 : 501 – 16 .
  • Johnson , R. E. , Cone , E. J. , Henningfield , J. E. and Fudala , P. J. 1989 . Use of buprenorphine in the treatment of opioid addiction. I. Physiologic and behavioral effects during a rapid dose induction . Clinical Pharmacology and Therapeutics , 46 ( 3 ) : 335 – 42 .
  • Johnson , R. E. and Fudala , P. J. 1992 . “ Development of buprenorphine for the treatment of opioid dependence. ” . In Buprenorphine: An Alternative Treatment for Opioid Dependence. , NIDA Research Monograph 121 Edited by: Blaine , J. Washington , D.C : U.S. GPO. . DHHS Pub. No. (ADM)92–1912
  • Johnson , R. E. , Jaffe , J. H. and Fudala , P. J. 1992 . a controlled trial of buprenorphine treatment for opioid dependence . Journal of the American Medical Association , 267 ( 20 ) : 2750 – 55 .
  • Judson , B. A. and Goldstein , A. 1983 . Episodes of heroin use during maintenance treatment with stable dosage of levo-alpha-acetylmethadol . Drug and Alcohol Dependence , 11 : 271 – 78 .
  • Keats , A. S. and Beecher , H. K. 1952 . Analgesic activity and toxic effects of acetylmethadol isomers in man . Journal of Pharmacology and Experimental Therapeutics , 105 ( 2 ) : 210 – 15 .
  • Kosten , T. R. , Kleber , H. D. and Morgan , C. 1989 . Treatment of cocaine abuse with buprenorphine . Biological Psychiatry , 26 : 637 – 39 .
  • Kosten , T. K. , Morgan , C. and Kleber , H. D. 1992 . “ Phase II clinical trials of buprenorphine: Detoxification and induction onto naltrexone. ” . In Buprenorphine: An Alternative Treatment for Opioid Dependence. , NIDA Research Monograph 121 Edited by: Blaine , J. Washington , D.C. : U.S. GPO. . DHHS Pub. No. (ADM)92–1912
  • Kosten , T. R. , Morgan , C. and Kleber , H. D. 1991 . Treatment of heroin addicts using buprenorphine . American Journal of Drug and Alcohol Abuse , 17 ( 2 ) : 119 – 28 .
  • Kosten , T. R. , Schottenfeld , R. , Ziedonis , D. and Falcioni , J. 1993 . Buprenorphine versus methadone maintenance for opioid dependence . Journal of Nervous and Mental Disease , 181 ( 6 ) : 358 – 64 .
  • Kreek , M. J. 1991 . “ Using methadone effectively: Achieving goals by application of laboratory, clinical and evaluation research and by development of innovative programs. ” . In Improving Drug Abuse Treatment. , NIDA Research Monograph 106 Edited by: Pickens , R. W. , Leukfeld , C. G. and Schuster , C. R. Washington , D.C. : U.S. GPO. .
  • Lange , W. R. , Fudala , P. J. , Dax , E. M. and Johnson , R. E. 1990 . Safety and side effects of buprenorphine in the clinical management of heroin addiction . Drug and Alcohol Dependence , 26 : 19 – 28 .
  • Levine , R. , Zaks , A. , Fink , M. and Freedman , A. M. 1976 . “ Levomethadyl acetate: Prolonged duration of opioid effects, including cross-tolerance to heroin. ” . In Rx: 3x/week LAAM. Alternative to Methadone. , NIDA Research Monograph 8 Edited by: Blaine , J. D. and Renault , P. F. Rockville , Maryland : National Institute on Drug Abuse. .
  • Lewis , J. W. 1985 . Buprenorphine . Drug and Alcohol Dependence , 14 : 363 – 72 .
  • Lewis , J. W. and Walker , D. 1992 . “ Buprenorphine–Background to its development as a treatment for opioid dependence. ” . In Buprenorphine: An Alternative Treatment for Opioid Dependence. , NIDA Research Monograph 121 Edited by: Blaine , J. Washington , D.C. : U.S. GPO. . DHHS Pub. No. (ADM)92–1912
  • Ling , W. and Blaine , J. D. 1979 . “ The use of LAAM in treatment. ” . In Handbook on Drug Abuse. Edited by: Dupont , R. L. , Goldstein , A. and O'Donnell , J. Washington , D.C. : U.S. GPO. .
  • Ling , W. , Charuvastra , S. C. , Kaim , S. C. and Klett , J. 1976 . Methadyl acetate and methadone as maintenance treatments for heroin addicts: A Veterans Administration cooperative study . Archives of General Psychiatry , 33 : 709 – 20 .
  • Ling , W. , Klett , J. and Gillis , R. 1978 . A cooperative clinical study of methadyl acetate . Archives of General Psychiatry , 35 : 345 – 53 .
  • Marcovici , M. , O'Brien , C , McLellan , T. and Kacian , J. 1981 . A clinical controlled study of L-alpha-acetylmethadol in the treatment of narcotic addiction . American Journal of Psychiatry , 138 : 234 – 36 .
  • Mello , N. K. and Mendelson , J. H. 1980 . Buprenorphine suppresses heroin use by heroin addicts . Science , 207 : 657 – 59 .
  • Mello , N. K. , Mendelson , J. H. and Kuehnle , J. C. 1982 . Buprenorphine effects on human heroin self-administration: An operant analysis . Journal of Pharmacology and Experimental Therapeutics , 223 ( 1 ) : 30 – 39 .
  • Mello , N. K. , Mendelson , J. H. , Lukas , S. E. , Gastfriend , D. R. , Teoh , S. K. and Holman , B. L. 1993 . Buprenorphine treatment of opioid and cocaine abuse: Clinical and preclinical studies . Harvard Review of Psychiatry , 1 ( 3 ) : 168 – 83 .
  • Mendelson , J. H. and Mello , N. K . 1992 . “ Human laboratory studies of buprenorphine. ” . In Buprenorphine: An Alternative Treatment for Opioid Dependence. , NIDA Research Monograph 121 Edited by: Blaine , J. Washington , D.C : U.S. GPO. . DHHS Pub. No. (ADM)92–1912
  • Neil , A. 1984 . Affinities of some common opioid analgesics towards four binding sites in mouse brain . Naunyn-Schmiedebergs Archives of Pharmacology , 328 : 24 – 29 .
  • New York State, Division of Substance Abuse Services . 1985 . Estimated Social and Governmental Costs of an Untreated Drug Abuser. New York : Division of Substance Abuse Services. .
  • Rounsaville , B. J. and Kleber , H. D. 1985 . Untreated opioid addicts . Archives of General Psychiatry , 42 : 1072 – 77 .
  • San , L. , Cami , J. , Fernandez , T. , Olle , J. M. , Peri , J. M. and Torrens , M. 1992 . Assessment and management of opioid withdrawal symptoms in buprenorphine-dependent subjects . British Journal of Addiction , 87 : 55 – 62 .
  • Savage , C. , Karp , E. G. , Curran , S. F. , Hanlon , T. E. and McCabe , O. L. 1976 . Methadone/LAAM maintenance: A comparison study . Comprehensive Psychiatry , 17 ( 3 ) : 415 – 24 .
  • Segest , E. , Mygind , O. and Bay , H. 1990 . The influence of prolonged stable methadone maintenance treatment on mortality and employment: An 8-year follow-up . International Journal of the Addictions , 25 ( 1 ) : 53 – 63 .
  • Senay , E. C. , Dorus , W. and Renault , R. F. 1977 . Methadyl acetate and methadone: An open comparison . Journal of the American Medical Association , 237 : 138 – 42 .
  • Senay , E. C. and Uchtenhagen , A. 1990 . “ Methadone in the treatment of opioid dependence: A review of the world literature. ” . In Methadone Maintenance in the Management of Opioid Dependence-An International Review. Edited by: Westermeyer , J. and Arif , A. New York : Praeger. .
  • Tennant , F. S. , Rawson , R. A. , Pumphrey , E. and Seecof , R. 1986 . Clinical experience with 959 opioid-dependent patients treated with levo-alpha-acetylmethadol (LAAM) . Journal of Substance Abuse Treatment , 3 : 195 – 202 .
  • Trueblood , B. , Judson , B. A. and Goldstein , A. 1978 . Acceptability of methadyI acetate (LAAM) as compared with methadone in a treatment program for heroin addicts . Drug and Alcohol Dependence , 3 : 125 – 32 .
  • Whysner , J. A. 1976 . “ Phase III clinical study of levo-alpha-acetylmethadol. ” . In Rx: 3x/week LAAM, Alternative to Methadone , NIDA Research Monograph 8 Edited by: Blaine , J. D. and Renault , P. F. Washington , D.C. : U.S. GPO. .
  • Wilson , B. K. , Spannagel , V. and Thomson , C. P. 1976 . The use of l-alpha-acethymethadol in treatment of heroin addiction: An open study . International Journal of the Addictions , 11 ( 6 ) : 1091 – 100 .
  • Zaks , A. , Fink , M. and Freedman , A. M. 1972 . Levomethadyl in maintenance treatment of opioid dependence . Journal of the American Medical Association , 220 : 811 – 13 .

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